E2F Activation of S Phase Promoters via Association with HCF-1 and the MLL Family of Histone H3K4 Methyltransferases

Molecular Cell

Volumn 27, Issue 1, 2007, Pages 107-119

  Tyagi, Shweta ^a,b   Chabes, Anna Lena ^b   Wysocka, Joanna ^b   Herr, Winship ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

CELLCYCLE; DNA

Indexed keywords

HISTONE DEACETYLASE; HISTONE H3K4 METHYLTRANSFERASE; METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL PROLIFERATION; DNA VIRUS; HELA CELL; HUMAN; HUMAN CELL; INSECT CELL; MOLECULAR INTERACTION; PROTEIN BINDING;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; E2F TRANSCRIPTION FACTORS; EVOLUTION, MOLECULAR; G1 PHASE; HELA CELLS; HISTONE DEACETYLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HOST CELL FACTOR C1; HUMANS; LYSINE; MOLECULAR SEQUENCE DATA; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P130; S PHASE; TWO-HYBRID SYSTEM TECHNIQUES;

HEXAPODA;

EID: 34250823511     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.05.030     Document Type: Article

References (53)

1. Balciunaite E., Spektor A., Lents N.H., Cam H., Te Riele H., Scime A., Rudnicki M.A., Young R., and Dynlacht B.D. Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells. Mol. Cell. Biol. 25 (2005) 8166-8178
2. Bandara L.R., Buck V.M., Zamanian M., Johnston L.H., and La Thangue N.B. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J. 12 (1993) 4317-4324
3. Blais A., and Dynlacht B.D. Hitting their targets: an emerging picture of E2F and cell cycle control. Curr. Opin. Genet. Dev. 14 (2004) 527-532
4. de Bruyn Kops A., and Knipe D.M. Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell 55 (1988) 857-868
5. Dignam J.D., Lebovitz R.M., and Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11 (1983) 1475-1489
6. Dimova D.K., and Dyson N.J. The E2F transcriptional network: old acquaintances with new faces. Oncogene 24 (2005) 2810-2826
7. Dou Y., Milne T.A., Tackett A.J., Smith E.R., Fukuda A., Wysocka J., Allis C.D., Chait B.T., Hess J.L., and Roeder R.G. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121 (2005) 873-885
8. Dreijerink K.M., Mulder K.W., Winkler G.S., Hoppener J.W., Lips C.J., and Timmers H.T. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer Res. 66 (2006) 4929-4935
9. Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 12 (1998) 2245-2262
10. El Messaoudi S., Fabbrizio E., Rodriguez C., Chuchana P., Fauquier L., Cheng D., Theillet C., Vandel L., Bedford M.T., and Sardet C. Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene. Proc. Natl. Acad. Sci. USA 103 (2006) 13351-13356
11. Freiman R.N., and Herr W. Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP. Genes Dev. 11 (1997) 3122-3127
12. Gerster T., and Roeder R.G. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc. Natl. Acad. Sci. USA 85 (1988) 6347-6351
13. Goto H., Motomura S., Wilson A.C., Freiman R.N., Nakabeppu Y., Fukushima K., Fujishima M., Herr W., and Nishimoto T. A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function. Genes Dev. 11 (1997) 726-737
14. Guelman S., Suganuma T., Florens L., Swanson S.K., Kiesecker C.L., Kusch T., Anderson S., Yates III J.R., Washburn M.P., Abmayr S.M., and Workman J.L. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Mol. Cell. Biol. 26 (2006) 871-882
15. Guenther M.G., Jenner R.G., Chevalier B., Nakamura T., Croce C.M., Canaani E., and Young R.A. Global and Hox-specific roles for the MLL1 methyltransferase. Proc. Natl. Acad. Sci. USA 102 (2005) 8603-8608
16. Harbour J.W., and Dean D.C. Rb function in cell-cycle regulation and apoptosis. Nat. Cell Biol. 2 (2000) E65-E67
17. Hess J.L. MLL: a histone methyltransferase disrupted in leukemia. Trends Mol. Med. 10 (2004) 500-507
18. Hsu S.I., Yang C.M., Sim K.G., Hentschel D.M., O'Leary E., and Bonventre J.V. TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. EMBO J. 20 (2001) 2273-2285
19. Julien E., and Herr W. Proteolytic processing is necessary to separate and ensure proper cell growth and cytokinesis functions of HCF-1. EMBO J. 22 (2003) 2360-2369
20. Julien E., and Herr W. A switch in mitotic histone H4 lysine 20 methylation status is linked to M phase defects upon loss of HCF-1. Mol. Cell 14 (2004) 713-725
21. Knez J., Piluso D., Bilan P., and Capone J.P. Host cell factor-1 and E2F4 interact via multiple determinants in each protein. Mol. Cell. Biochem. 288 (2006) 79-90
22. Krek W., Ewen M.E., Shirodkar S., Arany Z., Kaelin Jr. W.G., and Livingston D.M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78 (1994) 161-172
23. Kristie T.M., Pomerantz J.L., Twomey T.C., Parent S.A., and Sharp P.A. The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides. J. Biol. Chem. 270 (1995) 4387-4394
24. Lai A., Lee J.M., Yang W.M., DeCaprio J.A., Kaelin Jr. W.G., Seto E., and Branton P.E. RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins. Mol. Cell. Biol. 19 (1999) 6632-6641
25. Lang S.E., McMahon S.B., Cole M.D., and Hearing P. E2F transcriptional activation requires TRRAP and GCN5 cofactors. J. Biol. Chem. 276 (2001) 32627-32634
26. Lee C., Chang J.H., Lee H.S., and Cho Y. Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor. Genes Dev. 16 (2002) 3199-3212
27. Lindeman G.J., Gaubatz S., Livingston D.M., and Ginsberg D. The subcellular localization of E2F-4 is cell-cycle dependent. Proc. Natl. Acad. Sci. USA 94 (1997) 5095-5100
28. Louie M.C., Zou J.X., Rabinovich A., and Chen H.W. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol. Cell. Biol. 24 (2004) 5157-5171
29. Lowe E.D., Tews I., Cheng K.Y., Brown N.R., Gul S., Noble M.E., Gamblin S.J., and Johnson L.N. Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. Biochemistry 41 (2002) 15625-15634
30. Lu R., Yang P., Padmakumar S., and Misra V. The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF. J. Virol. 72 (1998) 6291-6297
31. Luciano R.L., and Wilson A.C. HCF-1 functions as a coactivator for the zinc finger protein Krox20. J. Biol. Chem. 278 (2003) 51116-51124
32. Mahajan S.S., Johnson K.M., and Wilson A.C. Molecular cloning of Drosophila HCF reveals proteolytic processing and self-association of the encoded protein. J. Cell. Physiol. 194 (2003) 117-126
33. Milne T.A., Dou Y., Martin M.E., Brock H.W., Roeder R.G., and Hess J.L. MLL associates specifically with a subset of transcriptionally active target genes. Proc. Natl. Acad. Sci. USA 102 (2005) 14765-14770
34. Milne T.A., Hughes C.M., Lloyd R., Yang Z., Rozenblatt-Rosen O., Dou Y., Schnepp R.W., Krankel C., Livolsi V.A., Gibbs D., et al. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proc. Natl. Acad. Sci. USA 102 (2005) 749-754
35. Rayman J.B., Takahashi Y., Indjeian V.B., Dannenberg J.H., Catchpole S., Watson R.J., te Riele H., and Dynlacht B.D. E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev. 16 (2002) 933-947
36. Reilly P.T., Wysocka J., and Herr W. Inactivation of the retinoblastoma protein family can bypass the HCF-1 defect in tsBN67 cell proliferation and cytokinesis. Mol. Cell. Biol. 22 (2002) 6767-6778
37. Rubin S.M., Gall A.L., Zheng N., and Pavletich N.P. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell 123 (2005) 1093-1106
38. Ruthenburg A.J., Allis C.D., and Wysocka J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol. Cell 25 (2007) 15-30
39. Shilatifard A. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu. Rev. Biochem. 75 (2006) 243-269
40. Sierra J., Yoshida T., Joazeiro C.A., and Jones K.A. The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 20 (2006) 586-600
41. Smith E.R., Cayrou C., Huang R., Lane W.S., Cote J., and Lucchesi J.C. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Mol. Cell. Biol. 25 (2005) 9175-9188
42. Takahashi Y., Rayman J.B., and Dynlacht B.D. Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev. 14 (2000) 804-816
43. Takeda S., Chen D.Y., Westergard T.D., Fisher J.K., Rubens J.A., Sasagawa S., Kan J.T., Korsmeyer S.J., Cheng E.H., and Hsieh J.J. Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. Genes Dev. 20 (2006) 2397-2409
44. Trimarchi J.M., and Lees J.A. Sibling rivalry in the E2F family. Nat. Rev. Mol. Cell Biol. 3 (2002) 11-20
45. Wells J., Boyd K.E., Fry C.J., Bartley S.M., and Farnham P.J. Target gene specificity of E2F and pocket protein family members in living cells. Mol. Cell. Biol. 20 (2000) 5797-5807
46. Wilson A.C., LaMarco K., Peterson M.G., and Herr W. The VP16 accessory protein HCF-1 is a family of polypeptides processed from a large precursor protein. Cell 74 (1993) 115-125
47. Wilson A.C., Peterson M.G., and Herr W. The HCF repeat is an unusual proteolytic cleavage signal. Genes Dev. 9 (1995) 2445-2458
48. Wysocka J., and Herr W. The herpes simplex virus VP16-induced complex: the makings of a regulatory switch. Trends Biochem. Sci. 28 (2003) 294-304
49. Wysocka J., Reilly P.T., and Herr W. Loss of HCF-1-chromatin association precedes temperature-induced growth arrest of tsBN67 cells. Mol. Cell. Biol. 21 (2001) 3820-3829
50. Wysocka J., Myers M.P., Laherty C.D., Eisenman R.N., and Herr W. Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev. 17 (2003) 896-911
51. Wysocka J., Swigut T., Xiao H., Milne T.A., Kwon S.Y., Landry J., Kauer M., Tackett A.J., Chait B.T., Badenhorst P., et al. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442 (2006) 86-90
52. Xu M., Sheppard K.A., Peng C.Y., Yee A.S., and Piwnica-Worms H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol. 14 (1994) 8420-8431
53. Yokoyama A., Wang Z., Wysocka J., Sanyal M., Aufiero D.J., Kitabayashi I., Herr W., and Cleary M.L. Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol. Cell. Biol. 24 (2004) 5639-5649