Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

Nature

Volumn 431, Issue 7011, 2004, Pages 1002-1007

  Hock, Hanno ^a,b   Hamblen, Melanie J ^a,c   Rooke, Heather M ^a,c   Schindler, Jeffrey W ^a   Saleque, Shireen ^a   Fujiwara, Yuko ^a,c   Orkin, Stuart H ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOTECHNOLOGY; BONE; IRRADIATION; TRANSPLANTS;

FUNCTIONAL INTEGRITY; SELF-RENEWAL CAPACITY;

CELL CULTURE;

BROXURIDINE; COMPLEMENTARY DNA; PROTEIN GFI 1; REPRESSOR PROTEIN; RNA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

MEDICINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL CYCLE; CELL FUNCTION; CELL PROLIFERATION; CELL RENEWAL; CHIMERA; CONTROLLED STUDY; EX VIVO STUDY; HEMATOPOIETIC STEM CELL; IMMUNOPHENOTYPING; IN VIVO STUDY; LETHAL MUTANT; LYMPHOID CELL; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; STEADY STATE; TRANSCRIPTION REGULATION; TRANSPLANTATION;

ANIMALS; ANTIGENS, CD45; BONE MARROW TRANSPLANTATION; BROMODEOXYURIDINE; CELL CYCLE; CELL DIVISION; DNA-BINDING PROTEINS; GENE DELETION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; IMMUNOPHENOTYPING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TRANSCRIPTION FACTORS;

ANIMALIA; CHIMAERIFORMES;

EID: 7244231429     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02994     Document Type: Article

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