-
1
-
-
0034614576
-
Stem cells: Units of development, units of regeneration, and units in evolution
-
Weissman, I. L. Stem cells: units of development, units of regeneration, and units in evolution. Cell 100, 157-168 (2000).
-
(2000)
Cell
, vol.100
, pp. 157-168
-
-
Weissman, I.L.1
-
2
-
-
75749146169
-
Coexistence of quiescent and active adult stem cells in mammals
-
Li, L. & Clevers, H. Coexistence of quiescent and active adult stem cells in mammals. Science 327, 542-545 (2010).
-
(2010)
Science
, vol.327
, pp. 542-545
-
-
Li, L.1
Clevers, H.2
-
3
-
-
38349132624
-
Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation
-
Orford, K. W. & Scadden, D. T. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nature Rev. Genet. 9, 115-128 (2008).
-
(2008)
Nature Rev. Genet.
, vol.9
, pp. 115-128
-
-
Orford, K.W.1
Scadden, D.T.2
-
4
-
-
0000607018
-
Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage
-
Howard, A. & Pelc, S. R. Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage. Hered. (Lond.) [Suppl.] 6, 261-273 (1953).
-
(1953)
Hered. (Lond.) [Suppl.]
, vol.6
, pp. 261-273
-
-
Howard, A.1
Pelc, S.R.2
-
5
-
-
84981755696
-
Biochemistry of the cell cycle: A review
-
Baserga, R. Biochemistry of the cell cycle: a review. Cell Prolifer. 1, 167-191 (1968).
-
(1968)
Cell Prolifer.
, vol.1
, pp. 167-191
-
-
Baserga, R.1
-
6
-
-
0001428312
-
Radiation effects on cell renewal and related systems
-
Patt, H. M. & Quastler, H. Radiation effects on cell renewal and related systems. Physiol. Rev. 43, 357-396 (1963).
-
(1963)
Physiol. Rev.
, vol.43
, pp. 357-396
-
-
Patt, H.M.1
Quastler, H.2
-
7
-
-
0015514709
-
The Leeuwenhoek Lecture, 1971: Tumour viruses and the sociology of fibroblasts
-
Stoker, M. G. P. The Leeuwenhoek Lecture, 1971: tumour viruses and the sociology of fibroblasts. Proc. R. Soc. Series B, Biol. Sci. 181, 1-17 (1972).
-
(1972)
Proc. R. Soc. Series B, Biol. Sci.
, vol.181
, pp. 1-17
-
-
Stoker, M.G.P.1
-
8
-
-
0015136814
-
Stimulation by serum of multiplication of stationary chicken cells
-
Temin, H. M. Stimulation by serum of multiplication of stationary chicken cells. J. Cell. Physiol. 78, 161-170 (1971).
-
(1971)
J. Cell. Physiol.
, vol.78
, pp. 161-170
-
-
Temin, H.M.1
-
9
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
Pardee, A. B. A restriction point for control of normal animal cell proliferation. Proc. Natl Acad. Sci. USA 71, 1286-1290 (1974).
-
(1974)
Proc. Natl Acad. Sci. USA
, vol.71
, pp. 1286-1290
-
-
Pardee, A.B.1
-
10
-
-
0021855166
-
Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
-
Zetterberg, A. & Larsson, O. Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl Acad. Sci. USA 82, 5365-5369 (1985).
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 5365-5369
-
-
Zetterberg, A.1
Larsson, O.2
-
11
-
-
2942584864
-
'Sleeping beauty': Quiescence in Saccharomyces cerevisiae
-
Gray, J. V. et al. 'Sleeping beauty': quiescence in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 68, 187-206 (2004).
-
(2004)
Microbiol. Mol. Biol. Rev.
, vol.68
, pp. 187-206
-
-
Gray, J.V.1
-
12
-
-
0005680712
-
A model of seed dormancy
-
Amen, R. D. A model of seed dormancy. Bot. Rev. 34, 1-31 (1968).
-
(1968)
Bot. Rev.
, vol.34
, pp. 1-31
-
-
Amen, R.D.1
-
13
-
-
2542601615
-
Liver regeneration and repair: Hepatocytes, progenitor cells, and stem cells
-
Fausto, N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology 39, 1477-1487 (2004).
-
(2004)
Hepatology
, vol.39
, pp. 1477-1487
-
-
Fausto, N.1
-
15
-
-
35348875982
-
Molecular signature of quiescent satellite cells in adult skeletal muscle
-
Fukada, S. et al. Molecular signature of quiescent satellite cells in adult skeletal muscle. Stem Cells 25, 2448-2459 (2007).
-
(2007)
Stem Cells
, vol.25
, pp. 2448-2459
-
-
Fukada, S.1
-
16
-
-
0020694123
-
Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
-
Gerdes, J., Schwab, U., Lemke, H. & Stein, H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int. J. Cancer 31, 13-20 (1983).
-
(1983)
Int. J. Cancer
, vol.31
, pp. 13-20
-
-
Gerdes, J.1
Schwab, U.2
Lemke, H.3
Stein, H.4
-
17
-
-
34249056493
-
High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny
-
Conboy, M. J., Karasov, A. O. & Rando, T. A. High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol. 5, e102 (2007).
-
(2007)
PLoS Biol.
, vol.5
-
-
Conboy, M.J.1
Karasov, A.O.2
Rando, T.A.3
-
18
-
-
33745762804
-
Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
-
Shinin, V., Gayraud-Morel, B., Gomès, D. & Tajbakhsh, S. Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nature Cell Biol. 8, 677-687 (2006).
-
(2006)
Nature Cell Biol.
, vol.8
, pp. 677-687
-
-
Shinin, V.1
Gayraud-Morel, B.2
Gomès, D.3
Tajbakhsh, S.4
-
19
-
-
0025313294
-
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
-
Cotsarelis, G., Sun, T. T. & Lavker, R. M. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337 (1990).
-
(1990)
Cell
, vol.61
, pp. 1329-1337
-
-
Cotsarelis, G.1
Sun, T.T.2
Lavker, R.M.3
-
20
-
-
0018034237
-
The segregation of DNA in epithelial stem cells
-
Potten, C. S., Hume, W. J., Reid, P. & Cairns, J. The segregation of DNA in epithelial stem cells. Cell 15, 899-906 (1978).
-
(1978)
Cell
, vol.15
, pp. 899-906
-
-
Potten, C.S.1
Hume, W.J.2
Reid, P.3
Cairns, J.4
-
21
-
-
0347634454
-
Defining the epithelial stem cell niche in skin
-
Tumbar, T. et al. Defining the epithelial stem cell niche in skin. Science 303, 359-363 (2004).
-
(2004)
Science
, vol.303
, pp. 359-363
-
-
Tumbar, T.1
-
22
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
Wilson, A. et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135, 1118-1129 (2008).
-
(2008)
Cell
, vol.135
, pp. 1118-1129
-
-
Wilson, A.1
-
23
-
-
60149104597
-
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
-
Foudi, A. et al. Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nature Biotechnol. 27, 84-90 (2008).
-
(2008)
Nature Biotechnol.
, vol.27
, pp. 84-90
-
-
Foudi, A.1
-
24
-
-
84867676626
-
The aged niche disrupts muscle stem cell quiescence
-
Chakkalakal, J. V., Jones, K. M., Basson, M. A. & Brack, A. S. The aged niche disrupts muscle stem cell quiescence. Nature 490, 355-360 (2012).
-
(2012)
Nature
, vol.490
, pp. 355-360
-
-
Chakkalakal, J.V.1
Jones, K.M.2
Basson, M.A.3
Brack, A.S.4
-
25
-
-
84874730918
-
Intestinal label-retaining cells are secretory precursors expressing Lgr5
-
Buczacki, S. J. A. et al. Intestinal label-retaining cells are secretory precursors expressing Lgr5. Nature 495, 65-69 (2013).
-
(2013)
Nature
, vol.495
, pp. 65-69
-
-
Buczacki, S.J.A.1
-
26
-
-
0019599627
-
Identification and behavior of label-retaining cells in oral mucosa and skin
-
Bickenbach, J. R. Identification and behavior of label-retaining cells in oral mucosa and skin. J. Dent. Res. 60, 1611-1620 (1981).
-
(1981)
J. Dent. Res.
, vol.60
, pp. 1611-1620
-
-
Bickenbach, J.R.1
-
27
-
-
84862527941
-
Tissue stem cells: New tools and functional diversity
-
Grompe, M. Tissue stem cells: new tools and functional diversity. Cell Stem Cell 10, 685-689 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 685-689
-
-
Grompe, M.1
-
28
-
-
83255193921
-
Interconversion between intestinal stem cell populations in distinct niches
-
Takeda, N. et al. Interconversion between intestinal stem cell populations in distinct niches. Science 334, 1420-1424 (2011).
-
(2011)
Science
, vol.334
, pp. 1420-1424
-
-
Takeda, N.1
-
29
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003-1007 (2007).
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
-
30
-
-
73049116186
-
+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6, 25-36 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
-
31
-
-
1842529559
-
Capturing and profiling adult hair follicle stem cells
-
Morris, R. J. et al. Capturing and profiling adult hair follicle stem cells. Nature Biotechol. 22, 411-417 (2004).
-
(2004)
Nature Biotechol.
, vol.22
, pp. 411-417
-
-
Morris, R.J.1
-
32
-
-
55049112939
-
Lgr5 marks cycling, yet long-lived, hair follicle stem cells
-
Jaks, V. et al. Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nature Genet. 40, 1291-1299 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 1291-1299
-
-
Jaks, V.1
-
33
-
-
84864280567
-
Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration
-
Rompolas, P. et al. Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration. Nature 487, 496-499 (2012).
-
(2012)
Nature
, vol.487
, pp. 496-499
-
-
Rompolas, P.1
-
34
-
-
33947104197
-
A single type of progenitor cell maintains normal epidermis
-
Clayton, E. et al. A single type of progenitor cell maintains normal epidermis. Nature 446, 185-189 (2007).
-
(2007)
Nature
, vol.446
, pp. 185-189
-
-
Clayton, E.1
-
35
-
-
28644451449
-
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
-
Ito, M. et al. Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nature Med. 11, 1351-1354 (2005).
-
(2005)
Nature Med.
, vol.11
, pp. 1351-1354
-
-
Ito, M.1
-
36
-
-
80855130470
-
Distinct stem cells contribute to mammary gland development and maintenance
-
Van Keymeulen, A. et al. Distinct stem cells contribute to mammary gland development and maintenance. Nature 479, 189-193 (2011).
-
(2011)
Nature
, vol.479
, pp. 189-193
-
-
Van Keymeulen, A.1
-
37
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton, M. et al. Generation of a functional mammary gland from a single stem cell. Nature 439, 84-88 (2006).
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
-
38
-
-
84869084046
-
Multipotent and unipotent progenitors contribute to prostate postnatal development
-
Ousset, M. et al. Multipotent and unipotent progenitors contribute to prostate postnatal development. Nature Cell Biol. 14, 1131-1138 (2012).
-
(2012)
Nature Cell Biol.
, vol.14
, pp. 1131-1138
-
-
Ousset, M.1
-
39
-
-
75949096894
-
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
-
Joe, A. W. B. et al. Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nature Cell Biol. 12, 153-163 (2010).
-
(2010)
Nature Cell Biol.
, vol.12
, pp. 153-163
-
-
Joe, A.W.B.1
-
40
-
-
75949130333
-
Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
-
Uezumi, A., Fukada, S., Yamamoto, N., Takeda, S. & Tsuchida, K. Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle. Nature Cell Biol. 12, 143-152 (2010).
-
(2010)
Nature Cell Biol.
, vol.12
, pp. 143-152
-
-
Uezumi, A.1
Fukada, S.2
Yamamoto, N.3
Takeda, S.4
Tsuchida, K.5
-
41
-
-
0023922373
-
Purification and characterization of mouse hematopoietic stem cells
-
Spangrude, G. J., Heimfeld, S. & Weissman, I. L. Purification and characterization of mouse hematopoietic stem cells. Science 241, 58-62 (1988).
-
(1988)
Science
, vol.241
, pp. 58-62
-
-
Spangrude, G.J.1
Heimfeld, S.2
Weissman, I.L.3
-
42
-
-
84864131103
-
The Lgr5 intestinal stem cell signature: Robust expression of proposed quiescent '+4' cell markers
-
Muñoz, J. et al. The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers. EMBO J. 31, 3079-3091 (2012).
-
(2012)
EMBO J.
, vol.31
, pp. 3079-3091
-
-
Muñoz, J.1
-
43
-
-
4444290010
-
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
-
Blanpain, C., Lowry, W. E., Geoghegan, A., Polak, L. & Fuchs, E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118, 635-648 (2004).
-
(2004)
Cell
, vol.118
, pp. 635-648
-
-
Blanpain, C.1
Lowry, W.E.2
Geoghegan, A.3
Polak, L.4
Fuchs, E.5
-
44
-
-
65549112127
-
Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny
-
Pastrana, E., Cheng, L.-C. & Doetsch, F. Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny. Proc. Natl Acad. Sci. USA 106, 6387-6392 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 6387-6392
-
-
Pastrana, E.1
Cheng, L.-C.2
Doetsch, F.3
-
45
-
-
77649335651
-
Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells
-
Forsberg, E. C. et al. Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. PLoS ONE 5, e8785 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Forsberg, E.C.1
-
46
-
-
0026583746
-
Cyclin A is required at two points in the human cell cycle
-
Pagano, M., Pepperkok, R., Verde, F., Ansorge, W. & Draetta, G. Cyclin A is required at two points in the human cell cycle. EMBO J. 11, 961-971 (1992).
-
(1992)
EMBO J.
, vol.11
, pp. 961-971
-
-
Pagano, M.1
Pepperkok, R.2
Verde, F.3
Ansorge, W.4
Draetta, G.5
-
47
-
-
0032547954
-
Cyclin E2: A novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle
-
Lauper, N. et al. Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle. Oncogene 17, 2637-2643 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 2637-2643
-
-
Lauper, N.1
-
48
-
-
67650638697
-
Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells
-
Kalaszczynska, I. et al. Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells. Cell 138, 352-365 (2009).
-
(2009)
Cell
, vol.138
, pp. 352-365
-
-
Kalaszczynska, I.1
-
50
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
Li, F. et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396, 580-584 (1998).
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
-
51
-
-
84863115641
-
Maintenance of muscle stem-cell quiescence by microRNA-489
-
Cheung, T. H. et al. Maintenance of muscle stem-cell quiescence by microRNA-489. Nature 482, 524-528 (2012).
-
(2012)
Nature
, vol.482
, pp. 524-528
-
-
Cheung, T.H.1
-
52
-
-
79955570371
-
MicroRNA programs in normal and aberrant stem and progenitor cells
-
Arnold, C. P. et al. microRNA programs in normal and aberrant stem and progenitor cells. Genome Res. 21, 798-810 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 798-810
-
-
Arnold, C.P.1
-
53
-
-
79952126479
-
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment
-
Zhang, L., Stokes, N., Polak, L. & Fuchs, E. Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell 8, 294-308 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, pp. 294-308
-
-
Zhang, L.1
Stokes, N.2
Polak, L.3
Fuchs, E.4
-
54
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B. E., Meissner, A. & Lander, E. S. The mammalian epigenome. Cell 128, 669-681 (2007).
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
55
-
-
76749083433
-
Jarid2 and PRC2, partners in regulating gene expression
-
Li, G. et al. Jarid2 and PRC2, partners in regulating gene expression. Genes Dev. 24, 368-380 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 368-380
-
-
Li, G.1
-
56
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006).
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
57
-
-
79952220410
-
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
-
Ezhkova, E. et al. EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev. 25, 485-498 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 485-498
-
-
Ezhkova, E.1
-
58
-
-
79955459714
-
Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells
-
Juan, A. H. et al. Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Genes Dev. 25, 789-794 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 789-794
-
-
Juan, A.H.1
-
59
-
-
33344469959
-
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga, L. M. et al. The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107, 2170-2179 (2006).
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
-
60
-
-
84868340057
-
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest
-
Hidalgo, I. et al. Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest. Cell Stem Cell 11, 649-662 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 649-662
-
-
Hidalgo, I.1
-
61
-
-
80052298366
-
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage
-
Lien, W.-H. et al. Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage. Cell Stem Cell 9, 219-232 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 219-232
-
-
Lien, W.-H.1
-
62
-
-
84876076090
-
Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation
-
Woodhouse, S., Pugazhendhi, D., Brien, P. & Pell, J. M. Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation. J. Cell. Sci. 126, 565-579 (2013).
-
(2013)
J. Cell. Sci.
, vol.126
, pp. 565-579
-
-
Woodhouse, S.1
Pugazhendhi, D.2
Brien, P.3
Pell, J.M.4
-
63
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther, M. G., Levine, S. S., Boyer, L. A., Jaenisch, R. & Young, R. A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130, 77-88 (2007).
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
64
-
-
58049216794
-
P53 regulates hematopoietic stem cell quiescence
-
Liu, Y. et al. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 4, 37-48 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 37-48
-
-
Liu, Y.1
-
65
-
-
0034629129
-
cip1/waf1
-
cip1/waf1. Science 287, 1804-1808 (2000).
-
(2000)
Science
, vol.287
, pp. 1804-1808
-
-
Cheng, T.1
-
66
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell 81, 323-330 (1995).
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
67
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
Harbour, J. W. & Dean, D. C. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 14, 2393-2409 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
68
-
-
75649109727
-
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes
-
Jacques, T. S. et al. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. EMBO J. 29, 222-235 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 222-235
-
-
Jacques, T.S.1
-
69
-
-
0033635597
-
1 control causing immortalization and increased cell turnover under growth-restricting conditions
-
1 control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev. 14, 3051-3064 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
Van Rossum, A.2
Schuijff, L.3
Te Riele, H.4
-
70
-
-
79957608573
-
Rb1 gene inactivation expands satellite cell and postnatal myoblast pools
-
Hosoyama, T., Nishijo, K., Prajapati, S. I., Li, G. & Keller, C. Rb1 gene inactivation expands satellite cell and postnatal myoblast pools. J. Biol. Chem. 286, 19556-19564 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19556-19564
-
-
Hosoyama, T.1
Nishijo, K.2
Prajapati, S.I.3
Li, G.4
Keller, C.5
-
71
-
-
52949114971
-
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
-
Viatour, P. et al. Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell 3, 416-428 (2008).
-
(2008)
Cell Stem Cell
, vol.3
, pp. 416-428
-
-
Viatour, P.1
-
72
-
-
15444377643
-
P21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
-
Kippin, T. E. & Martens, D. J. & van der Kooy, D. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. Genes Dev. 19, 756-767 (2005).
-
(2005)
Genes Dev.
, vol.19
, pp. 756-767
-
-
Kippin, T.E.1
Martens, D.J.2
Van Der Kooy, D.3
-
74
-
-
80052289298
-
P57 is required for quiescence and maintenance of adult hematopoietic stem cells
-
Matsumoto, A. et al. p57 is required for quiescence and maintenance of adult hematopoietic stem cells. Cell Stem Cell 9, 262-271 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 262-271
-
-
Matsumoto, A.1
-
75
-
-
80052281899
-
Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
-
Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 9, 247-261 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 247-261
-
-
Zou, P.1
-
76
-
-
24344443668
-
The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis
-
Luo, D., Renault, V. M. & Rando, T. A. The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin. Cell Dev. Biol. 16, 612-622 (2005).
-
(2005)
Semin. Cell Dev. Biol.
, vol.16
, pp. 612-622
-
-
Luo, D.1
Renault, V.M.2
Rando, T.A.3
-
77
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S., Rand, M. D. & Lake, R. J. Notch signaling: cell fate control and signal integration in development. Science 284, 770-776 (1999).
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
78
-
-
84862942273
-
Notch signaling is necessary to maintain quiescence in adult muscle stem cells
-
Bjornson, C. R. R. et al. Notch signaling is necessary to maintain quiescence in adult muscle stem cells. Stem Cells 30, 232-242 (2012).
-
(2012)
Stem Cells
, vol.30
, pp. 232-242
-
-
Bjornson, C.R.R.1
-
79
-
-
84856118451
-
A critical requirement for Notch signaling in maintenance of the quiescent skeletal muscle stem cell state
-
Mourikis, P. et al. A critical requirement for Notch signaling in maintenance of the quiescent skeletal muscle stem cell state. Stem Cells 30, 243-252 (2012).
-
(2012)
Stem Cells
, vol.30
, pp. 243-252
-
-
Mourikis, P.1
-
80
-
-
77953511847
-
Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells
-
Chapouton, P. et al. Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells. J. Neurosci. 30, 7961-7974 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 7961-7974
-
-
Chapouton, P.1
-
81
-
-
41449089457
-
Canonical Notch signaling is dispensable for the maintenance of adult hematopoietic stem cells
-
Maillard, I. et al. Canonical Notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell 2, 356-366 (2008).
-
(2008)
Cell Stem Cell
, vol.2
, pp. 356-366
-
-
Maillard, I.1
-
82
-
-
40649107714
-
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis
-
Estrach, S., Cordes, R., Hozumi, K., Gossler, A. & Watt, F. M. Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J. Invest. Dermatol. 128, 825-832 (2007).
-
(2007)
J. Invest. Dermatol.
, vol.128
, pp. 825-832
-
-
Estrach, S.1
Cordes, R.2
Hozumi, K.3
Gossler, A.4
Watt, F.M.5
-
83
-
-
79951784680
-
Asymmetric cell divisions promote Notch-dependent epidermal differentiation
-
Williams, S. E., Beronja, S., Pasolli, H. A. & Fuchs, E. Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature 470, 353-358 (2011).
-
(2011)
Nature
, vol.470
, pp. 353-358
-
-
Williams, S.E.1
Beronja, S.2
Pasolli, H.A.3
Fuchs, E.4
-
84
-
-
0036744815
-
The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
-
Conboy, I. M. & Rando, T. A. The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev. Cell 3, 397-409 (2002).
-
(2002)
Dev. Cell
, vol.3
, pp. 397-409
-
-
Conboy, I.M.1
Rando, T.A.2
-
85
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
86
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim, L. P., Glasner, M. E., Yekta, S., Burge, C. B. & Bartel, D. P. Vertebrate microRNA genes. Science 299, 1540-1540 (2003).
-
(2003)
Science
, vol.299
, pp. 1540-1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
87
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D. P. microRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
88
-
-
84870894496
-
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
-
Lechman, E. R. et al. Attenuation of miR-126 activity expands HSC in vivo without exhaustion. Cell Stem Cell 11, 799-811 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 799-811
-
-
Lechman, E.R.1
-
89
-
-
77956270732
-
MicroRNA miR-125a controls hematopoietic stem cell number
-
Guo, S. et al. microRNA miR-125a controls hematopoietic stem cell number. Proc. Natl Acad. Sci. USA 107, 14229-14234 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14229-14234
-
-
Guo, S.1
-
90
-
-
33644525948
-
The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK
-
Ageberg, M., Gullberg, U. & Lindmark, A. The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK. Haematologica 91, 268-269 (2006).
-
(2006)
Haematologica
, vol.91
, pp. 268-269
-
-
Ageberg, M.1
Gullberg, U.2
Lindmark, A.3
-
91
-
-
84863623509
-
Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules
-
Crist, C. G., Montarras, D. & Buckingham, M. Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules. Cell Stem Cell 11, 118-126 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 118-126
-
-
Crist, C.G.1
Montarras, D.2
Buckingham, M.3
-
92
-
-
84863230221
-
Alternative polyadenylation mediates microRNA regulation of muscle stem cell function
-
Boutet, S. C. et al. Alternative polyadenylation mediates microRNA regulation of muscle stem cell function. Cell Stem Cell 10, 327-336 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 327-336
-
-
Boutet, S.C.1
-
93
-
-
84155163076
-
Brain-derived neurotrophic factor expression is repressed during myogenic differentiation by miR-206
-
Miura, P., Amirouche, A., Clow, C., Bélanger, G. & Jasmin, B. J. Brain-derived neurotrophic factor expression is repressed during myogenic differentiation by miR-206. J. Neurochem. 120, 230-238 (2012).
-
(2012)
J. Neurochem.
, vol.120
, pp. 230-238
-
-
Miura, P.1
Amirouche, A.2
Clow, C.3
Bélanger, G.4
Jasmin, B.J.5
-
94
-
-
46249092601
-
Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites
-
Sandberg, R., Neilson, J. R., Sarma, A., Sharp, P. A. & Burge, C. B. Proliferating cells express mRNAs with shortened 3′ untranslated regions and fewer microRNA target sites. Science 320, 1643-1647 (2008).
-
(2008)
Science
, vol.320
, pp. 1643-1647
-
-
Sandberg, R.1
Neilson, J.R.2
Sarma, A.3
Sharp, P.A.4
Burge, C.B.5
-
95
-
-
68749113985
-
Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
-
Mayr, C. & Bartel, D. P. Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 138, 673-684 (2009).
-
(2009)
Cell
, vol.138
, pp. 673-684
-
-
Mayr, C.1
Bartel, D.P.2
-
96
-
-
70350569286
-
Mechanisms of alternative splicing regulation: Insights from molecular and genomics approaches
-
Chen, M. & Manley, J. L. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nature Rev. Mol. Cell. Biol. 10, 741-754 (2009).
-
(2009)
Nature Rev. Mol. Cell. Biol.
, vol.10
, pp. 741-754
-
-
Chen, M.1
Manley, J.L.2
-
97
-
-
80052979140
-
Mechanisms and consequences of alternative polyadenylation
-
Di Giammartino, D. C., Nishida, K. & Manley, J. L. Mechanisms and consequences of alternative polyadenylation. Mol. Cell 43, 853-866 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 853-866
-
-
Di Giammartino, D.C.1
Nishida, K.2
Manley, J.L.3
-
98
-
-
84877929784
-
All's well that ends well: Alternative polyadenylation and its implications for stem cell biology
-
Mueller, A. A., Cheung, T. H. & Rando, T. A. All's well that ends well: alternative polyadenylation and its implications for stem cell biology. Curr. Opin. Cell Biol. 25, 22-32 (2013).
-
(2013)
Curr. Opin. Cell Biol.
, vol.25
, pp. 22-32
-
-
Mueller, A.A.1
Cheung, T.H.2
Rando, T.A.3
-
99
-
-
77949538391
-
Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types
-
Ji, Z. & Tian, B. Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types. PLoS ONE 4, e8419 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Ji, Z.1
Tian, B.2
-
100
-
-
80052266532
-
MicroRNAs can generate thresholds in target gene expression
-
Mukherji, S. et al. microRNAs can generate thresholds in target gene expression. Nature Genet. 43, 854-859 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 854-859
-
-
Mukherji, S.1
-
101
-
-
28944439309
-
Animal microRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution
-
Stark, A., Brennecke, J., Bushati, N., Russell, R. B. & Cohen, S. M. Animal microRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell 123, 1133-1146 (2005).
-
(2005)
Cell
, vol.123
, pp. 1133-1146
-
-
Stark, A.1
Brennecke, J.2
Bushati, N.3
Russell, R.B.4
Cohen, S.M.5
-
102
-
-
29144505309
-
The widespread impact of mammalian microRNAs on mRNA repression and evolution
-
Farh, K. K.-H. et al. The widespread impact of mammalian microRNAs on mRNA repression and evolution. Science 310, 1817-1821 (2005).
-
(2005)
Science
, vol.310
, pp. 1817-1821
-
-
Farh, K.K.-H.1
-
103
-
-
33745614062
-
Stem cells, ageing and the quest for immortality
-
Rando, T. A. Stem cells, ageing and the quest for immortality. Nature 441, 1080-1086 (2006).
-
(2006)
Nature
, vol.441
, pp. 1080-1086
-
-
Rando, T.A.1
-
104
-
-
33846243745
-
An integrated view of oxidative stress in aging: Basic mechanisms, functional effects, and pathological considerations
-
Kregel, K. C. & Zhang, H. J. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R18-R36 (2007).
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.292
-
-
Kregel, K.C.1
Zhang, H.J.2
-
105
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
Rossi, D. J., Jamieson, C. H. M. & Weissman, I. L. Stems cells and the pathways to aging and cancer. Cell 132, 681-696 (2008).
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.M.2
Weissman, I.L.3
-
106
-
-
34547660196
-
FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
-
Tothova, Z. & Gilliland, D. G. FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system. Cell Stem Cell 1, 140-152 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 140-152
-
-
Tothova, Z.1
Gilliland, D.G.2
-
107
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova, Z. et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128, 325-339 (2007).
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
-
108
-
-
70350506802
-
FoxO3 regulates neural stem cell homeostasis
-
Renault, V. M. et al. FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5, 527-539 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, pp. 527-539
-
-
Renault, V.M.1
-
109
-
-
84863316388
-
Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity
-
Latil, M. et al. Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity. Nature Commun. 3, 903 (2012).
-
(2012)
Nature Commun.
, vol.3
, pp. 903
-
-
Latil, M.1
-
110
-
-
79957534554
-
Blood vessels and the satellite cell niche
-
Mounier, R., Chrétien, F. & Chazaud, B. Blood vessels and the satellite cell niche. Curr. Top. Dev. Biol. 96, 121-138 (2011).
-
(2011)
Curr. Top. Dev. Biol.
, vol.96
, pp. 121-138
-
-
Mounier, R.1
Chrétien, F.2
Chazaud, B.3
-
111
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
Simsek, T. et al. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell 7, 380-390 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 380-390
-
-
Simsek, T.1
-
112
-
-
34248359065
-
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
-
Parmar, K., Mauch, P., Vergilio, J.-A., Sackstein, R. & Down, J. D. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl Acad. Sci. USA 104, 5431-5436 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 5431-5436
-
-
Parmar, K.1
Mauch, P.2
Vergilio, J.-A.3
Sackstein, R.4
Down, J.D.5
-
113
-
-
78549254160
-
0 state by CD34-positive cord blood cells after bone marrow transplantation
-
0 state by CD34-positive cord blood cells after bone marrow transplantation. Exp. Hematol. 38, 1231-1240 (2010).
-
(2010)
Exp. Hematol.
, vol.38
, pp. 1231-1240
-
-
Shima, H.1
-
115
-
-
80053916176
-
Metabolic regulation of hematopoietic stem cells in the hypoxic niche
-
Suda, T., Takubo, K. & Semenza, G. L. Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Cell Stem Cell 9, 298-310 (2011).
-
(2011)
Cell Stem Cell
, vol.9
, pp. 298-310
-
-
Suda, T.1
Takubo, K.2
Semenza, G.L.3
-
116
-
-
77956217067
-
Regulation of the HIF-1α level is essential for hematopoietic stem cells
-
Takubo, K. et al. Regulation of the HIF-1α level is essential for hematopoietic stem cells. Cell Stem Cell 7, 391-402 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 391-402
-
-
Takubo, K.1
-
117
-
-
84865289879
-
LKB1 and AMPK: Central regulators of lymphocyte metabolism and function
-
Blagih, J., Krawczyk, C. M. & Jones, R. G. LKB1 and AMPK: central regulators of lymphocyte metabolism and function. Immunol. Rev. 249, 59-71 (2012).
-
(2012)
Immunol. Rev.
, vol.249
, pp. 59-71
-
-
Blagih, J.1
Krawczyk, C.M.2
Jones, R.G.3
-
118
-
-
78649851511
-
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
-
Gurumurthy, S. et al. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468, 659-663 (2010).
-
(2010)
Nature
, vol.468
, pp. 659-663
-
-
Gurumurthy, S.1
-
119
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
Gan, B. et al. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468, 701-704 (2010).
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
-
120
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada, D., Saunders, T. L. & Morrison, S. J. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468, 653-658 (2010).
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
121
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky, D. J. & Emr, S. D. Autophagy as a regulated pathway of cellular degradation. Science 290, 1717-1721 (2000).
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
122
-
-
79952728102
-
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
-
Mortensen, M. et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J. Exp. Med. 208, 455-467 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 455-467
-
-
Mortensen, M.1
-
123
-
-
13944249618
-
DNA repair, genome stability, and aging
-
Lombard, D. B. et al. DNA repair, genome stability, and aging. Cell 120, 497-512 (2005).
-
(2005)
Cell
, vol.120
, pp. 497-512
-
-
Lombard, D.B.1
-
124
-
-
3943107573
-
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
-
Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K. & Linn, S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73, 39-85 (2004).
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 39-85
-
-
Sancar, A.1
Lindsey-Boltz, L.A.2
Ünsal-Kaçmaz, K.3
Linn, S.4
-
125
-
-
38049155945
-
Regulation of DNA double-strand break repair pathway choice
-
Shrivastav, M., Haro, L. P. D. & Nickoloff, J. A. Regulation of DNA double-strand break repair pathway choice. Cell Res. 18, 134-147 (2008).
-
(2008)
Cell Res.
, vol.18
, pp. 134-147
-
-
Shrivastav, M.1
Haro, L.P.D.2
Nickoloff, J.A.3
-
126
-
-
77956251480
-
Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis
-
Mohrin, M. et al. Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell 7, 174-185 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 174-185
-
-
Mohrin, M.1
-
127
-
-
0016692602
-
Mutation selection and the natural history of cancer
-
Cairns, J. Mutation selection and the natural history of cancer. Nature 255, 197-200 (1975).
-
(1975)
Nature
, vol.255
, pp. 197-200
-
-
Cairns, J.1
-
128
-
-
79251479414
-
Stem cell ageing and non-random chromosome segregation
-
Charville, G. W. & Rando, T. A. Stem cell ageing and non-random chromosome segregation. Phil. Trans. R. Soc., B, Biol. Sci. 366, 85-93 (2011).
-
(2011)
Phil. Trans. R. Soc., B, Biol. Sci.
, vol.366
, pp. 85-93
-
-
Charville, G.W.1
Rando, T.A.2
-
129
-
-
84856096903
-
A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division
-
Rocheteau, P., Gayraud-Morel, B., Siegl-Cachedenier, I., Blasco, M. A. & Tajbakhsh, S. A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division. Cell 148, 112-125 (2012).
-
(2012)
Cell
, vol.148
, pp. 112-125
-
-
Rocheteau, P.1
Gayraud-Morel, B.2
Siegl-Cachedenier, I.3
Blasco, M.A.4
Tajbakhsh, S.5
-
130
-
-
73849129204
-
Identification of sister chromatids by DNA template strand sequences
-
Falconer, E. et al. Identification of sister chromatids by DNA template strand sequences. Nature 463, 93-97 (2009).
-
(2009)
Nature
, vol.463
, pp. 93-97
-
-
Falconer, E.1
-
131
-
-
0036591968
-
Intestinal stem cells protect their genome by selective segregation of template DNA strands
-
Potten, C. S., Owen, G. & Booth, D. Intestinal stem cells protect their genome by selective segregation of template DNA strands. J. Cell. Sci. 115, 2381-2388 (2002).
-
(2002)
J. Cell. Sci.
, vol.115
, pp. 2381-2388
-
-
Potten, C.S.1
Owen, G.2
Booth, D.3
-
132
-
-
24144490682
-
Support for the immortal strand hypothesis: Neural stem cells partition DNA asymmetrically in vitro
-
Karpowicz, P. et al. Support for the immortal strand hypothesis: neural stem cells partition DNA asymmetrically in vitro. J. Cell Biol. 170, 721-732 (2005).
-
(2005)
J. Cell Biol.
, vol.170
, pp. 721-732
-
-
Karpowicz, P.1
-
133
-
-
34250740943
-
The immortal strand hypothesis: Segregation and reconstruction
-
Rando, T. A. The immortal strand hypothesis: segregation and reconstruction. Cell 129, 1239-1243 (2007).
-
(2007)
Cell
, vol.129
, pp. 1239-1243
-
-
Rando, T.A.1
-
134
-
-
34250728609
-
Immortal strands? Give me a break
-
Lansdorp, P. M. Immortal strands? Give me a break. Cell 129, 1244-1247 (2007).
-
(2007)
Cell
, vol.129
, pp. 1244-1247
-
-
Lansdorp, P.M.1
-
135
-
-
34548601610
-
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
-
Kiel, M. J. et al. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449, 238-242 (2007).
-
(2007)
Nature
, vol.449
, pp. 238-242
-
-
Kiel, M.J.1
-
136
-
-
56249107718
-
The majority of multipotent epidermal stem cells do not protect their genome by asymmetrical chromosome segregation
-
Sotiropoulou, P. A., Candi, A. & Blanpain, C. The majority of multipotent epidermal stem cells do not protect their genome by asymmetrical chromosome segregation. Stem Cells 26, 2964-2973 (2008).
-
(2008)
Stem Cells
, vol.26
, pp. 2964-2973
-
-
Sotiropoulou, P.A.1
Candi, A.2
Blanpain, C.3
-
137
-
-
0024797066
-
Random segregation of DNA strands in epidermal basal cells
-
Kuroki, T. & Murakami, Y. Random segregation of DNA strands in epidermal basal cells. Jpn J. Cancer Res. 80, 637-642 (1989).
-
(1989)
Jpn J. Cancer Res.
, vol.80
, pp. 637-642
-
-
Kuroki, T.1
Murakami, Y.2
-
138
-
-
79952751557
-
Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes
-
Schepers, A. G., Vries, R., van den Born, M., van de Wetering, M. & Clevers, H. Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes. EMBO J. 30, 1104-1109 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 1104-1109
-
-
Schepers, A.G.1
Vries, R.2
Van Den Born, M.3
Van De Wetering, M.4
Clevers, H.5
-
139
-
-
33947224690
-
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
-
Linsley, P. S. et al. Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol. Cell. Biol. 27, 2240-2252 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2240-2252
-
-
Linsley, P.S.1
-
140
-
-
70249104647
-
Defining mechanisms that regulate RNA polymerase II transcription in vivo
-
Fuda, N. J., Ardehali, M. B. & Lis, J. T. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 461, 186-192 (2009).
-
(2009)
Nature
, vol.461
, pp. 186-192
-
-
Fuda, N.J.1
Ardehali, M.B.2
Lis, J.T.3
-
141
-
-
14444275279
-
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
-
Wada, T. et al. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev. 12, 343-356 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 343-356
-
-
Wada, T.1
-
142
-
-
0033515521
-
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
-
Yamaguchi, Y. et al. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97, 41-51 (1999).
-
(1999)
Cell
, vol.97
, pp. 41-51
-
-
Yamaguchi, Y.1
-
143
-
-
0029959881
-
Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase
-
Marshall, N. F., Peng, J., Xie, Z. & Price, D. H. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase. J. Biol. Chem. 271, 27176-27183 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27176-27183
-
-
Marshall, N.F.1
Peng, J.2
Xie, Z.3
Price, D.H.4
-
144
-
-
77951920690
-
C-Myc regulates transcriptional pause release
-
Rahl, P. B. et al. c-Myc regulates transcriptional pause release. Cell 141, 432-445 (2010).
-
(2010)
Cell
, vol.141
, pp. 432-445
-
-
Rahl, P.B.1
-
145
-
-
44349116852
-
The transition from transcriptional initiation to elongation
-
Wade, J. T. & Struhl, K. The transition from transcriptional initiation to elongation. Curr. Opin. Genet. Dev. 18, 130-136 (2008).
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 130-136
-
-
Wade, J.T.1
Struhl, K.2
-
146
-
-
79955795581
-
Paused RNA polymerase II as a developmental checkpoint
-
Levine, M. Paused RNA polymerase II as a developmental checkpoint. Cell 145, 502-511 (2011).
-
(2011)
Cell
, vol.145
, pp. 502-511
-
-
Levine, M.1
-
147
-
-
77956309058
-
Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation
-
Freter, R., Osawa, M. & Nishikawa, S. Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation. Stem cells 28, 1571-1580 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1571-1580
-
-
Freter, R.1
Osawa, M.2
Nishikawa, S.3
-
148
-
-
79551683487
-
Cellular senescence: Putting the paradoxes in perspective
-
Campisi, J. Cellular senescence: putting the paradoxes in perspective. Curr. Opin. Genet. Dev. 21, 107-112 (2011).
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 107-112
-
-
Campisi, J.1
-
149
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppé, J.-P. et al. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6, e301 (2008).
-
(2008)
PLoS Biol.
, vol.6
-
-
Coppé, J.-P.1
-
150
-
-
80855138775
-
Ink4a-positive senescent cells delays ageing-associated disorders
-
Ink4a-positive senescent cells delays ageing-associated disorders. Nature 479, 232-236 (2011).
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
-
151
-
-
0036346608
-
Plasticity and reprogramming of differentiated cells in amphibian regeneration
-
Brockes, J. P. & Kumar, A. Plasticity and reprogramming of differentiated cells in amphibian regeneration. Nature Rev. Mol. Cell Biol. 3, 566-574 (2002).
-
(2002)
Nature Rev. Mol. Cell Biol.
, vol.3
, pp. 566-574
-
-
Brockes, J.P.1
Kumar, A.2
-
152
-
-
0034651994
-
Plasticity of retrovirus-labelled myotubes in the newt limb regeneration blastema
-
Kumar, A., Velloso, C. P., Imokawa, Y. & Brockes, J. P. Plasticity of retrovirus-labelled myotubes in the newt limb regeneration blastema. Dev. Biol. 218, 125-136 (2000).
-
(2000)
Dev. Biol.
, vol.218
, pp. 125-136
-
-
Kumar, A.1
Velloso, C.P.2
Imokawa, Y.3
Brockes, J.P.4
-
153
-
-
0035923683
-
Mammalian myotube dedifferentiation induced by newt regeneration extract
-
McGann, C. J., Odelberg, S. J. & Keating, M. T. Mammalian myotube dedifferentiation induced by newt regeneration extract. Proc. Natl Acad. Sci. USA 98, 13699-13704 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 13699-13704
-
-
McGann, C.J.1
Odelberg, S.J.2
Keating, M.T.3
-
154
-
-
0028819587
-
Differential expression of myogenic regulatory genes and Msx-1 during dedifferentiation and redifferentiation of regenerating amphibian limbs
-
Simon, H.-G. et al. Differential expression of myogenic regulatory genes and Msx-1 during dedifferentiation and redifferentiation of regenerating amphibian limbs. Dev. Dynam. 202, 1-12 (1995).
-
(1995)
Dev. Dynam.
, vol.202
, pp. 1-12
-
-
Simon, H.-G.1
-
155
-
-
0034703978
-
Dedifferentiation of mammalian myotubes induced by msx1
-
Odelberg, S. J., Kollhoff, A. & Keating, M. T. Dedifferentiation of mammalian myotubes induced by msx1. Cell 103, 1099-1109 (2000).
-
(2000)
Cell
, vol.103
, pp. 1099-1109
-
-
Odelberg, S.J.1
Kollhoff, A.2
Keating, M.T.3
-
156
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beauséjour, C. M. et al. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J. 22, 4212-4222 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 4212-4222
-
-
Beauséjour, C.M.1
-
157
-
-
77956247987
-
Transient Inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle
-
Pajcini, K. V., Corbel, S. Y., Sage, J., Pomerantz, J. H. & Blau, H. M. Transient Inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell Stem Cell 7, 198-213 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 198-213
-
-
Pajcini, K.V.1
Corbel, S.Y.2
Sage, J.3
Pomerantz, J.H.4
Blau, H.M.5
-
158
-
-
84856078085
-
A family business: Stem cell progeny join the niche to regulate homeostasis
-
Hsu, Y.-C. & Fuchs, E. A family business: stem cell progeny join the niche to regulate homeostasis. Nature Rev. Mol. Cell Biol. 13, 103-114 (2012).
-
(2012)
Nature Rev. Mol. Cell Biol.
, vol.13
, pp. 103-114
-
-
Hsu, Y.-C.1
Fuchs, E.2
-
159
-
-
0018102359
-
The relationship between the spleen colony-forming cell and the haemopoietic stem cell
-
Schofield, R. The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4, 7-25 (1978).
-
(1978)
Blood Cells
, vol.4
, pp. 7-25
-
-
Schofield, R.1
-
160
-
-
84857985977
-
What does the concept of the stem cell niche really mean today?
-
Lander, A. D. et al. What does the concept of the stem cell niche really mean today? BMC Biol. 10, 19 (2012).
-
(2012)
BMC Biol.
, vol.10
, pp. 19
-
-
Lander, A.D.1
-
161
-
-
34547924424
-
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
Brack, A. S. et al. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317, 807-810 (2007).
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
-
162
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy, I. M. et al. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433, 760-764 (2005).
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
-
163
-
-
84856147560
-
Endothelial and perivascular cells maintain haematopoietic stem cells
-
Ding, L., Saunders, T. L., Enikolopov, G. & Morrison, S. J. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481, 457-462 (2012).
-
(2012)
Nature
, vol.481
, pp. 457-462
-
-
Ding, L.1
Saunders, T.L.2
Enikolopov, G.3
Morrison, S.J.4
-
164
-
-
0344827208
-
Notch-mediated restoration of regenerative potential to aged muscle
-
Conboy, I. M., Conboy, M. J., Smythe, G. M. & Rando, T. A. Notch-mediated restoration of regenerative potential to aged muscle. Science 302, 1575-1577 (2003).
-
(2003)
Science
, vol.302
, pp. 1575-1577
-
-
Conboy, I.M.1
Conboy, M.J.2
Smythe, G.M.3
Rando, T.A.4
|