-
1
-
-
0033529124
-
Instabilities in phosphorylation-dephosphorylation cascades and cell cycle checkpoints
-
AGUDA BD. (1999) Instabilities in phosphorylation-dephosphorylation cascades and cell cycle checkpoints. Oncogene 18, 2846.
-
(1999)
Oncogene
, vol.18
, pp. 2846
-
-
Aguda, B.D.1
-
3
-
-
0029050533
-
Deficiency of pRb leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
-
ALMASAN A, YIN Y, KELLY RE et al. (1995) Deficiency of pRb leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92, 5436.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5436
-
-
Almasan, A.1
Yin, Y.2
Kelly, R.E.3
-
4
-
-
0030561571
-
The retinoblastoma protein pathway and the restriction point
-
BARTER J, BARTKOVA J, LUKAS J. (1996) The retinoblastoma protein pathway and the restriction point. Curr. Opin. Cell Biol. 8, 805.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 805
-
-
Barter, J.1
Bartkova, J.2
Lukas, J.3
-
5
-
-
0031586604
-
The retinoblastoma protein pathway in cell cycle control and cancer
-
BARTER J, BARTKOVA J, LUKAS J. (1997) The retinoblastoma protein pathway in cell cycle control and cancer. Exptl. Cell Res. 237, 1.
-
(1997)
Exptl. Cell Res.
, vol.237
, pp. 1
-
-
Barter, J.1
Bartkova, J.2
Lukas, J.3
-
6
-
-
0031561477
-
E2F: A nodal point in cell cycle regulation
-
BERNARDS R. (1997) E2F: a nodal point in cell cycle regulation. Biochim. Biophys. Acta 1333, M33.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Bernards, R.1
-
7
-
-
0030903750
-
Regulation of E2F through ubiquitin-proteosome-dependent degradation: Stabilization by the pRB tumor suppressor protein
-
CAMPANERO MR, FLEMINGTON EK. (1997) Regulation of E2F through ubiquitin-proteosome-dependent degradation: stabilization by the pRB tumor suppressor protein. Proc. Natl. Acad. Sci. USA 94, 2221.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2221
-
-
Campanero, M.R.1
Flemington, E.K.2
-
8
-
-
0029664461
-
Requirement of p27Kip1 for R point control of the fibroblast cell cycle
-
COATS S, FLANAGAN WM, NOURSE J, ROBERTS JM. (1996) Requirement of p27Kip1 for R point control of the fibroblast cell cycle. Science 272, 877.
-
(1996)
Science
, vol.272
, pp. 877
-
-
Coats, S.1
Flanagan, W.M.2
Nourse, J.3
Roberts, J.M.4
-
9
-
-
15144341364
-
Expression of p16 induces transcriptional downregulation of the RB gene
-
FANG X, JIN X, XU H-J et al. (1998) Expression of p16 induces transcriptional downregulation of the RB gene. Oncogene 16, 1.
-
(1998)
Oncogene
, vol.16
, pp. 1
-
-
Fang, X.1
Jin, X.2
Xu, H.-J.3
-
10
-
-
0016038059
-
Dynamics of open chemical systems and the algebraic structure of the underlying reaction network
-
FEINBERG M, HORN FJM. (1974) Dynamics of open chemical systems and the algebraic structure of the underlying reaction network. Chem. Eng. Sci. 29, 775.
-
(1974)
Chem. Eng. Sci.
, vol.29
, pp. 775
-
-
Feinberg, M.1
Horn, F.J.M.2
-
11
-
-
0029779280
-
Cdc25 cell-cycle phosphatase as a target of c-myc
-
GALAKTIONOV K, CHEN X, BEACH D. (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382, 511.
-
(1996)
Nature
, vol.382
, pp. 511
-
-
Galaktionov, K.1
Chen, X.2
Beach, D.3
-
12
-
-
0029986337
-
Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
-
GENG Y, Ng EATON E, PICON M et al. (1996) Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12, 1173.
-
(1996)
Oncogene
, vol.12
, pp. 1173
-
-
Geng, Y.1
Ng Eaton, E.2
Picon, M.3
-
13
-
-
0029670477
-
Translational control of p27Kip1 accumulation during the cell cycle
-
HENGST L, REED SI. (1996) Translational control of p27Kip1 accumulation during the cell cycle. Science 271, 1861.
-
(1996)
Science
, vol.271
, pp. 1861
-
-
Hengst, L.1
Reed, S.I.2
-
14
-
-
0029863840
-
Altered cell cycle kinetics. gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
-
HERRERA RE, SAH VP, WILLIAMS BO, MAKELA TP, WEINBERG RA, JACKS T. (1996) Altered cell cycle kinetics. gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts. Mol. Cell. Biol. 16, 2402.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2402
-
-
Herrera, R.E.1
Sah, V.P.2
Williams, B.O.3
Makela, T.P.4
Weinberg, R.A.5
Jacks, T.6
-
15
-
-
0024670325
-
E1A-dependent transctivation of the human MYC promoter is mediated by the E2F factor
-
HIEBERT SW, LIPP M, NEVINS JR. (1989) E1A-dependent transctivation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci. USA 86, 3594.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 3594
-
-
Hiebert, S.W.1
Lipp, M.2
Nevins, J.R.3
-
16
-
-
0028022034
-
Activation of the phosphatase activity of human cdc25a by a cdk2-cyclin E dependent phosphorylation at the G1/S transition
-
HOFFMANN I, DRAETTA G, KARSENTI E. (1994) Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition. EMBO J. 13, 4302.
-
(1994)
EMBO J.
, vol.13
, pp. 4302
-
-
Hoffmann, I.1
Draetta, G.2
Karsenti, E.3
-
17
-
-
0029868367
-
A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation
-
IKEDA M, JAKOI L, NEVINS JR. (1996) A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl. Acad. Sci. USA 93, 3215.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3215
-
-
Ikeda, M.1
Jakoi, L.2
Nevins, J.R.3
-
18
-
-
0026649165
-
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
-
KOFF A, GIORDANO A, DESAI D et al. (1992) Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257, 1689.
-
(1992)
Science
, vol.257
, pp. 1689
-
-
Koff, A.1
Giordano, A.2
Desai, D.3
-
19
-
-
0032568043
-
Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition
-
KOHN KW. (1998) Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition. Oncogene 16, 1065.
-
(1998)
Oncogene
, vol.16
, pp. 1065
-
-
Kohn, K.W.1
-
20
-
-
0028362359
-
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
-
KREK W, EWEN ME, SHIRODKAR S, ARANY Z, KAELIN WG, LIVINGSTON DM. (1994) Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78, 161.
-
(1994)
Cell
, vol.78
, pp. 161
-
-
Krek, W.1
Ewen, M.E.2
Shirodkar, S.3
Arany, Z.4
Kaelin, W.G.5
Livingston, D.M.6
-
21
-
-
0030995824
-
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
LEONE G, DEGREGORI J, SEARS R, JAKOI L, NEVINS JR. (1997) Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387, 422.
-
(1997)
Nature
, vol.387
, pp. 422
-
-
Leone, G.1
Degregori, J.2
Sears, R.3
Jakoi, L.4
Nevins, J.R.5
-
22
-
-
0033536059
-
Collaborative role of E2F transcriptional activity and G1 cyclin-dependent kinase activity in the induction of S phase
-
LEONE G, DEGREGORI J, JAKOI L, COOK JG, NEVINS JR. (1999) Collaborative role of E2F transcriptional activity and G1 cyclin-dependent kinase activity in the induction of S phase. Proc. Natl. Acad. Sci. USA 96, 6626.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6626
-
-
Leone, G.1
Degregori, J.2
Jakoi, L.3
Cook, J.G.4
Nevins, J.R.5
-
23
-
-
0028034775
-
Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb
-
LI Y, NICHOLS MA, SHAY JW, XIONG Y. (1994) Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb. Cancer Res. 54, 6078.
-
(1994)
Cancer Res.
, vol.54
, pp. 6078
-
-
Li, Y.1
Nichols, M.A.2
Shay, J.W.3
Xiong, Y.4
-
24
-
-
0031008465
-
Cyclin E-induced S phase without activation of the pRb/E2F pathway
-
LUKAS J, HERZINGER T, HANSEN K et al. (1997) Cyclin E-induced S phase without activation of the pRb/E2F pathway. Genes Dev. 11, 1479.
-
(1997)
Genes Dev.
, vol.11
, pp. 1479
-
-
Lukas, J.1
Herzinger, T.2
Hansen, K.3
-
25
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
LUNDBERG AS, WEINBERG RA. (1998) Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Molec. Cell. Biol. 18, 753.
-
(1998)
Molec. Cell. Biol.
, vol.18
, pp. 753
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
26
-
-
0031935648
-
Control of pRB phosphorylation
-
MITTNACHT S. (1998) Control of pRB phosphorylation. Curr. Opin. Gen. Dev. 8, 21.
-
(1998)
Curr. Opin. Gen. Dev.
, vol.8
, pp. 21
-
-
Mittnacht, S.1
-
27
-
-
0031758421
-
Restriction point control in human cancer
-
MOROY T. (1998) Restriction point control in human cancer. Tumordiagn. U. Ther. 19, 93.
-
(1998)
Tumordiagn. U. Ther.
, vol.19
, pp. 93
-
-
Moroy, T.1
-
28
-
-
0028136903
-
Transcription of the E2F1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter
-
NEUMAN E, FLEMINGTON EK, SELLERS WR, KAELIN WG JR. (1994) Transcription of the E2F1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter. Mol. Cell. Biol. 14, 6607.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6607
-
-
Neuman, E.1
Flemington, E.K.2
Sellers, W.R.3
Kaelin Jr., W.G.4
-
29
-
-
0030731071
-
A mathematical model of the regulation of the G1 phase of Rb+/+ and Rb-/- mouse embryonic fibroblasts and an osteosarcoma cell line
-
OBEYESEKERE MN, KNUDSEN ES, WANG JYJ, ZIMMERMAN SO. (1997) A mathematical model of the regulation of the G1 phase of Rb+/+ and Rb-/- mouse embryonic fibroblasts and an osteosarcoma cell line. Cell Prolif. 30, 171.
-
(1997)
Cell Prolif.
, vol.30
, pp. 171
-
-
Obeyesekere, M.N.1
Knudsen, E.S.2
Wang, J.Y.J.3
Zimmerman, S.O.4
-
31
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
PARDEE AB. (1974) A restriction point for control of normal animal cell proliferation. Proc. Natl. Acad. Sci. USA 71, 1286.
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 1286
-
-
Pardee, A.B.1
-
32
-
-
0024473604
-
G1 events and regulation of cell proliferation
-
PARDEE AB (1989). G1 events and regulation of cell proliferation. Science 246, 603.
-
(1989)
Science
, vol.246
, pp. 603
-
-
Pardee, A.B.1
-
33
-
-
0030665150
-
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
-
POON RYC, CHAU MS, YAMASHITA K, HUNTER T. (1997) The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res. 57, 5168.
-
(1997)
Cancer Res.
, vol.57
, pp. 5168
-
-
Poon, R.Y.C.1
Chau, M.S.2
Yamashita, K.3
Hunter, T.4
-
34
-
-
0030573463
-
Cyclin E: In mid-cycle
-
REED SI. (1996) Cyclin E: in mid-cycle. Biochim. Biophys. Acta 1287, 151.
-
(1996)
Biochim. Biophys. Acta
, vol.1287
, pp. 151
-
-
Reed, S.I.1
-
35
-
-
0031948741
-
Key effectors of signal transduction and G1 progression
-
ROUSSEL MF. (1998) Key effectors of signal transduction and G1 progression. Adv. Cancer Res. 74, 1.
-
(1998)
Adv. Cancer Res.
, vol.74
, pp. 1
-
-
Roussel, M.F.1
-
37
-
-
0033590632
-
A rate limiting function of Cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2
-
SEXL V, DIEHL JA, SHERR CJ, ASHMUN R, BEACH D, ROUSSEL MF. (1999) A rate limiting function of Cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2. Oncogene 18, 573.
-
(1999)
Oncogene
, vol.18
, pp. 573
-
-
Sexl, V.1
Diehl, J.A.2
Sherr, C.J.3
Ashmun, R.4
Beach, D.5
Roussel, M.F.6
-
38
-
-
0030855138
-
Regulation of mammalian cyclin-dependent kinase 2
-
Dunphy WG, ed. New York: Academic Press
-
SHEAFF RJ. (1997) Regulation of mammalian cyclin-dependent kinase 2. In: Dunphy WG, ed. Cell Cycle Control (Methods in Enzymology, Vol 283). New York: Academic Press, 173.
-
(1997)
Cell Cycle Control Methods in Enzymology
, vol.283
, pp. 173
-
-
Sheaff, R.J.1
-
39
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27
-
SHEAFF RJ, GROUDINE M, GORDON M, ROBERTS JM, CLURMAN BE. (1997) Cyclin E-CDK2 is a regulator of p27. Genes Dev. 11, 1464.
-
(1997)
Genes Dev.
, vol.11
, pp. 1464
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
40
-
-
0030434467
-
Signal transduction of cell-cycle regulation: Its temporospacial architecture
-
TAKUWA N, TAKUWA Y. (1996) Signal transduction of cell-cycle regulation: its temporospacial architecture. Jap. J. Physiol. 46, 431.
-
(1996)
Jap. J. Physiol.
, vol.46
, pp. 431
-
-
Takuwa, N.1
Takuwa, Y.2
-
41
-
-
0030740210
-
Ras activity late in G1 phase required for p27Kip1 downregulation, passage through the Restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
-
TAKUWA N, TAKUWA Y. (1997) Ras activity late in G1 phase required for p27Kip1 downregulation, passage through the Restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell. Biol. 17, 5348.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5348
-
-
Takuwa, N.1
Takuwa, Y.2
-
42
-
-
0024651359
-
Nuclear factor E2F mediates basic transcription and transactivation by E1A of the human MYC promoter
-
THALMEIER K, SYNOVZIK H, MERTZ R, WINNACKER EL, LIPP M. (1989) Nuclear factor E2F mediates basic transcription and transactivation by E1A of the human MYC promoter. Genes Dev. 3, 527.
-
(1989)
Genes Dev.
, vol.3
, pp. 527
-
-
Thalmeier, K.1
Synovzik, H.2
Mertz, R.3
Winnacker, E.L.4
Lipp, M.5
-
43
-
-
0032980308
-
The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer
-
TSIHLIAS J, KAPUSTA L, SLINGERLAND J. (1999) The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. Annu. Rev. Med. 50, 401.
-
(1999)
Annu. Rev. Med.
, vol.50
, pp. 401
-
-
Tsihlias, J.1
Kapusta, L.2
Slingerland, J.3
-
45
-
-
0021855166
-
Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells
-
ZETTERBERO A, LARSSON O. (1985) Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA 82, 5365.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 5365
-
-
Zetterbero, A.1
Larsson, O.2
|