-
1
-
-
34249933089
-
Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications
-
Mankertz, J. & Schulzke, J.-D. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr. Opin. Gastroenterol. 23, 379-383 (2007).
-
(2007)
Curr. Opin. Gastroenterol
, vol.23
, pp. 379-383
-
-
Mankertz, J.1
Schulzke, J.-D.2
-
2
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley, J. M. et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Med. 12, 1365-1371 (2006).
-
(2006)
Nature Med
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
-
3
-
-
80053606297
-
Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection
-
Sandler, N. G. et al. Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection. Gastroenterology 141, 1220-1230 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 1220-1230
-
-
Sandler, N.G.1
-
4
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
Cani, P. D. et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56, 1761-1772 (2007).
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
-
5
-
-
80052278497
-
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: Molecular mechanisms and probiotic treatment
-
Amar, J. et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol. Med. 3, 559-572 (2011).
-
(2011)
EMBO Mol. Med
, vol.3
, pp. 559-572
-
-
Amar, J.1
-
6
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of type 1 diabetes
-
Wen, L. et al. Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 455, 1109-1113 (2008).
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
-
7
-
-
79952748674
-
Colloquium paper: Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
-
Lee, Y. K., Menezes, J. S., Umesaki, Y. & Mazmanian, S. K. Colloquium paper: Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl Acad. Sci. USA 108, 4615-4622 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4615-4622
-
-
Lee, Y.K.1
Menezes, J.S.2
Umesaki, Y.3
Mazmanian, S.K.4
-
8
-
-
81855167104
-
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
-
Berer, K. et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479, 538-541 (2011).
-
(2011)
Nature
, vol.479
, pp. 538-541
-
-
Berer, K.1
-
9
-
-
77953913586
-
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
-
Wu, H.-J. et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32, 815-827 (2010).
-
(2010)
Immunity
, vol.32
, pp. 815-827
-
-
Wu, H.-J.1
-
10
-
-
84876913132
-
Role of the gut microbiota in immunity and inflammatory disease
-
Kamada, N., Seo, S.-U., Chen, G. Y. & Nez, G. Role of the gut microbiota in immunity and inflammatory disease. Nature Rev. Immunol. 13, 321-335 (2013).
-
(2013)
Nature Rev. Immunol
, vol.13
, pp. 321-335
-
-
Kamada, N.1
Seo, S.-U.2
Chen, G.Y.3
Nez, G.4
-
11
-
-
84861980130
-
Interactions between the microbiota and the immune system
-
Hooper, L. V., Littman, D. R. & Macpherson, A. J. Interactions between the microbiota and the immune system. Science 336, 1268-1273 (2012).
-
(2012)
Science
, vol.336
, pp. 1268-1273
-
-
Hooper, L.V.1
Littman, D.R.2
Macpherson, A.J.3
-
12
-
-
84859389254
-
The microbiome in infectious disease and inflammation
-
Honda, K. & Littman, D. R. The microbiome in infectious disease and inflammation. Annu. Rev. Immunol. 30, 759-795 (2012).
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 759-795
-
-
Honda, K.1
Littman, D.R.2
-
13
-
-
84866167497
-
Reciprocal interactions of the intestinal microbiota and immune system
-
Maynard, C. L., Elson, C. O., Hatton, R. D. & Weaver, C. T. Reciprocal interactions of the intestinal microbiota and immune system. Nature 489, 231-241 (2012).
-
(2012)
Nature
, vol.489
, pp. 231-241
-
-
Maynard, C.L.1
Elson, C.O.2
Hatton, R.D.3
Weaver, C.T.4
-
14
-
-
84865278789
-
Viral interactions with the host and microbiota in the intestine
-
Moon, C. & Stappenbeck, T. S. Viral interactions with the host and microbiota in the intestine. Curr. Opin. Immunol. 24, 405-410 (2012).
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 405-410
-
-
Moon, C.1
Stappenbeck, T.S.2
-
15
-
-
33646182727
-
Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control
-
Crosnier, C., Stamataki, D. & Lewis, J. Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nature Rev. Genet. 7, 349-359 (2006).
-
(2006)
Nature Rev. Genet
, vol.7
, pp. 349-359
-
-
Crosnier, C.1
Stamataki, D.2
Lewis, J.3
-
16
-
-
67651159312
-
Stem cells, self-renewal, and differentiation in the intestinal epithelium
-
Van der Flier, L. G. & Clevers, H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71, 241-260 (2009).
-
(2009)
Annu. Rev. Physiol
, vol.71
, pp. 241-260
-
-
Van Der Flier, L.G.1
Clevers, H.2
-
17
-
-
77958170401
-
Intestinal goblet cells and mucins in health and disease: Recent insights and progress
-
Kim, Y. S. & Ho, S. B. Intestinal goblet cells and mucins in health and disease: recent insights and progress. Curr. Gastroenterol. Rep. 12, 319-330 (2010).
-
(2010)
Curr. Gastroenterol. Rep
, vol.12
, pp. 319-330
-
-
Kim, Y.S.1
Ho, S.B.2
-
18
-
-
84862862332
-
Epithelial antimicrobial defence of the skin and intestine
-
Gallo, R. L. & Hooper, L. V. Epithelial antimicrobial defence of the skin and intestine. Nature Rev. Immunol. 12, 503-516 (2012).
-
(2012)
Nature Rev. Immunol
, vol.12
, pp. 503-516
-
-
Gallo, R.L.1
Hooper, L.V.2
-
19
-
-
54449083567
-
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
-
Johansson, M. E. V. et al. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc. Natl Acad. Sci. USA 105, 15064-15069 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 15064-15069
-
-
Johansson, M.E.V.1
-
20
-
-
0036500996
-
Colorectal cancer in mice genetically deficient in the mucin Muc2
-
Velcich, A. et al. Colorectal cancer in mice genetically deficient in the mucin Muc2. Science 295, 1726-1729 (2002).
-
(2002)
Science
, vol.295
, pp. 1726-1729
-
-
Velcich, A.1
-
21
-
-
33745746660
-
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection
-
Van der Sluis, M. et al. Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection. Gastroenterology 131, 117-129 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 117-129
-
-
Van Der Sluis, M.1
-
22
-
-
0034681162
-
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis
-
Taupin, D. R., Kinoshita, K. & Podolsky, D. K. Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc. Natl Acad. Sci. USA 97, 799-804 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 799-804
-
-
Taupin, D.R.1
Kinoshita, K.2
Podolsky, D.K.3
-
23
-
-
0028360991
-
Trefoil peptides promote epithelial migration through a transforming growth factor ?-independent pathway
-
Dignass, A., Lynch-Devaney, K., Kindon, H., Thim, L. & Podolsky, D. K. Trefoil peptides promote epithelial migration through a transforming growth factor ?-independent pathway. J. Clin. Invest. 94, 376-383 (1994).
-
(1994)
J. Clin. Invest
, vol.94
, pp. 376-383
-
-
Dignass, A.1
Lynch-Devaney, K.2
Kindon, H.3
Thim, L.4
Podolsky, D.K.5
-
24
-
-
4544300682
-
RELM?/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract
-
Artis, D. et al. RELM?/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract. Proc. Natl Acad. Sci. USA 101, 13596-13600 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 13596-13600
-
-
Artis, D.1
-
25
-
-
58149286587
-
Goblet cell-derived resistin-like molecule ? Augments CD4+ T cell production of IFN-? And infection-induced intestinal inflammation
-
Nair, M. G. et al. Goblet cell-derived resistin-like molecule ? augments CD4+ T cell production of IFN-? and infection-induced intestinal inflammation. J. Immunol. 181, 4709-4715 (2008).
-
(2008)
J. Immunol
, vol.181
, pp. 4709-4715
-
-
Nair, M.G.1
-
26
-
-
79954915318
-
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
-
Bevins, C. L. & Salzman, N. H. Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. Nature Rev. Microbiol. 9, 356-368 (2011).
-
(2011)
Nature Rev. Microbiol
, vol.9
, pp. 356-368
-
-
Bevins, C.L.1
Salzman, N.H.2
-
27
-
-
84892373963
-
Antibacterial membrane attack by a pore-forming intestinal C-type lectin
-
Mukherjee, S. et al. Antibacterial membrane attack by a pore-forming intestinal C-type lectin. Nature 505, 103-107 (2014).
-
(2014)
Nature
, vol.505
, pp. 103-107
-
-
Mukherjee, S.1
-
28
-
-
33745343647
-
Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine
-
Darmoul, D. & Ouellette, A. J. Positional specificity of defensin gene expression reveals Paneth cell heterogeneity in mouse small intestine. Am. J. Physiol. 271, G68-G74 (1996).
-
(1996)
Am. J. Physiol
, vol.271
-
-
Darmoul, D.1
Ouellette, A.J.2
-
29
-
-
80054122238
-
The antibacterial lectin RegIII? Promotes the spatial segregation of microbiota and host in the intestine
-
Vaishnava, S. et al. The antibacterial lectin RegIII? promotes the spatial segregation of microbiota and host in the intestine. Science 334, 255-258 (2011).
-
(2011)
Science
, vol.334
, pp. 255-258
-
-
Vaishnava, S.1
-
30
-
-
44149126798
-
Secreted enteric antimicrobial activity localises to the mucus surface layer
-
Meyer-Hoffert, U. et al. Secreted enteric antimicrobial activity localises to the mucus surface layer. Gut 57, 764-771 (2008).
-
(2008)
Gut
, vol.57
, pp. 764-771
-
-
Meyer-Hoffert, U.1
-
31
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe, J. et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nature Genet. 39, 207-211 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
-
32
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux, J. D. et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nature Genet. 39, 596-604 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
-
33
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell, K. et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456, 259-263 (2008).
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
-
34
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser, A. et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 134, 743-756 (2008).
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
-
35
-
-
62549129560
-
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
-
Brandl, K. et al. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response. Proc. Natl Acad. Sci. USA 106, 3300-3305 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 3300-3305
-
-
Brandl, K.1
-
36
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohns disease gene Atg16L1 phenotypes in intestine
-
Cadwell, K. et al. Virus-plus-susceptibility gene interaction determines Crohns disease gene Atg16L1 phenotypes in intestine. Cell 141, 1135-1145 (2010).
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
-
37
-
-
79959216005
-
Genetics and pathogenesis of inflammatory bowel disease
-
Khor, B., Gardet, A. & Xavier, R. J. Genetics and pathogenesis of inflammatory bowel disease. Nature 474, 307-317 (2011).
-
(2011)
Nature
, vol.474
, pp. 307-317
-
-
Khor, B.1
Gardet, A.2
Xavier, R.J.3
-
38
-
-
84879107779
-
Intestinal epithelial autophagy is essential for host defense against invasive bacteria
-
Benjamin, J. L., Sumpter, R. Jr, Levine, B. & Hooper, L. V. Intestinal epithelial autophagy is essential for host defense against invasive bacteria. Cell Host Microbe 13, 723-734 (2013).
-
(2013)
Cell Host Microbe
, vol.13
, pp. 723-734
-
-
Benjamin, J.L.1
Sumpter Jr., R.2
Levine, B.3
Hooper, L.V.4
-
39
-
-
84887621906
-
Paneth cells as a site of origin for intestinal inflammation
-
Adolph, T. E. et al. Paneth cells as a site of origin for intestinal inflammation. Nature 503, 272-276 (2013).
-
(2013)
Nature
, vol.503
, pp. 272-276
-
-
Adolph, T.E.1
-
40
-
-
80054963764
-
Regulation of the polymeric immunoglobulin receptor and IgA transport: New advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity
-
Johansen, F.-E. & Kaetzel, C. S. Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity. Mucosal Immunol. 4, 598-602 (2011).
-
(2011)
Mucosal Immunol
, vol.4
, pp. 598-602
-
-
Johansen, F.-E.1
Kaetzel, C.S.2
-
41
-
-
0033523608
-
Absence of epithelial immunoglobulin a transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/ secretory component-deficient mice
-
Johansen, F.-E. et al. Absence of epithelial immunoglobulin a transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/ secretory component-deficient mice. J. Exp. Med. 190, 915-922 (1999).
-
(1999)
J. Exp. Med
, vol.190
, pp. 915-922
-
-
Johansen, F.-E.1
-
42
-
-
84856083002
-
Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut
-
Shulzhenko, N. et al. Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nature Med. 17, 1585-1593 (2011).
-
(2011)
Nature Med
, vol.17
, pp. 1585-1593
-
-
Shulzhenko, N.1
-
43
-
-
1242296822
-
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
-
Suzuki, K. et al. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc. Natl Acad. Sci. USA 101, 1981-1986 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 1981-1986
-
-
Suzuki, K.1
-
44
-
-
84879336857
-
Microfold (M) cells: Important immunosurveillance posts in the intestinal epithelium
-
Mabbott, N. A., Donaldson, D. S., Ohno, H., Williams, I. R. & Mahajan, A. Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 6, 666-677 (2013).
-
(2013)
Mucosal Immunol
, vol.6
, pp. 666-677
-
-
Mabbott, N.A.1
Donaldson, D.S.2
Ohno, H.3
Williams, I.R.4
Mahajan, A.5
-
45
-
-
0038316325
-
Anatomical basis of tolerance and immunity to intestinal antigens
-
Mowat, A. M. Anatomical basis of tolerance and immunity to intestinal antigens. Nature Rev. Immunol. 3, 331-341 (2003).
-
(2003)
Nature Rev. Immunol
, vol.3
, pp. 331-341
-
-
Mowat, A.M.1
-
46
-
-
70449653428
-
Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response
-
Hase, K. et al. Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response. Nature 462, 226-230 (2009).
-
(2009)
Nature
, vol.462
, pp. 226-230
-
-
Hase, K.1
-
47
-
-
84863230541
-
Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
-
McDole, J. R. et al. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature 483, 345-349 (2012).
-
(2012)
Nature
, vol.483
, pp. 345-349
-
-
McDole, J.R.1
-
48
-
-
0035321325
-
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
-
Rescigno, M. et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nature Immunol. 2, 361-367 (2001).
-
(2001)
Nature Immunol
, vol.2
, pp. 361-367
-
-
Rescigno, M.1
-
49
-
-
33845910419
-
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
-
Chieppa, M., Rescigno, M., Huang, A. Y. C. & Germain, R. N. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement. J. Exp. Med. 203, 2841-2852 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 2841-2852
-
-
Chieppa, M.1
Rescigno, M.2
Huang, A.Y.C.3
Germain, R.N.4
-
50
-
-
84886280379
-
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
-
Shan, M. et al. Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science 342, 447-453 (2013).
-
(2013)
Science
, vol.342
, pp. 447-453
-
-
Shan, M.1
-
51
-
-
75649093343
-
Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function
-
Abreu, M. T. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nature Rev. Immunol. 10, 131-144 (2010).
-
(2010)
Nature Rev. Immunol
, vol.10
, pp. 131-144
-
-
Abreu, M.T.1
-
52
-
-
81855228056
-
Inflammasomes in intestinal inflammation and cancer
-
Chen, G. Y. & Nez, G. Inflammasomes in intestinal inflammation and cancer. Gastroenterology 141, 1986-1999 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 1986-1999
-
-
Chen, G.Y.1
Nez, G.2
-
53
-
-
84874028928
-
Integrative inflammasome activity in the regulation of intestinal mucosal immune responses
-
Elinav, E., Henao-Mejia, J. & Flavell, R. A. Integrative inflammasome activity in the regulation of intestinal mucosal immune responses. Mucosal Immunol. 6, 4-13 (2013).
-
(2013)
Mucosal Immunol
, vol.6
, pp. 4-13
-
-
Elinav, E.1
Henao-Mejia, J.2
Flavell, R.A.3
-
54
-
-
80054810643
-
Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis
-
Li, X.-D. et al. Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis. Proc. Natl Acad. Sci. USA 108, 17390-17395 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 17390-17395
-
-
Li, X.-D.1
-
55
-
-
79251564770
-
RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium
-
Broquet, A. H., Hirata, Y., McAllister, C. S. & Kagnoff, M. F. RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium. J. Immunol. 186, 1618-1626 (2011).
-
(2011)
J. Immunol
, vol.186
, pp. 1618-1626
-
-
Broquet, A.H.1
Hirata, Y.2
McAllister, C.S.3
Kagnoff, M.F.4
-
56
-
-
3242664636
-
Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S. & Medzhitov, R. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241 (2004).
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
57
-
-
78650548872
-
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
-
Brandl, K. et al. MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proc. Natl Acad. Sci. USA 107, 19967-19972 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 19967-19972
-
-
Brandl, K.1
-
58
-
-
67649231565
-
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency
-
Podolsky, D. K., Gerken, G., Eyking, A. & Cario, E. Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency. Gastroenterology 137, 209-220 (2009).
-
(2009)
Gastroenterology
, vol.137
, pp. 209-220
-
-
Podolsky, D.K.1
Gerken, G.2
Eyking, A.3
Cario, E.4
-
59
-
-
3242692641
-
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
-
Cario, E., Gerken, G. & Podolsky, D. K. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology 127, 224-238 (2004).
-
(2004)
Gastroenterology
, vol.127
, pp. 224-238
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
60
-
-
4043088499
-
IKK? Links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten, F. R. et al. IKK? links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118, 285-296 (2004).
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
-
61
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
Nenci, A. et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 446, 557-561 (2007).
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
-
62
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohns disease
-
Hugot, J.-P. et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohns disease. Nature 411, 599-603 (2001).
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.-P.1
-
63
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohns disease
-
Ogura, Y. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohns disease. Nature 411, 603-606 (2001).
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
-
64
-
-
79953084107
-
The Nlrp3 inflammasome: Contributions to intestinal homeostasis
-
Zaki, M. H., Lamkanfi, M. & Kanneganti, T.-D. The Nlrp3 inflammasome: contributions to intestinal homeostasis. Trends Immunol. 32, 171-179 (2011).
-
(2011)
Trends Immunol
, vol.32
, pp. 171-179
-
-
Zaki, M.H.1
Lamkanfi, M.2
Kanneganti, T.-D.3
-
65
-
-
79957670765
-
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases
-
Swanson, P. A. et al. Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc. Natl Acad. Sci. USA 108, 8803-8808 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 8803-8808
-
-
Swanson, P.A.1
-
66
-
-
84873816901
-
Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair
-
Leoni, G. et al. Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair. J. Clin. Invest. 123, 443-454 (2012).
-
(2012)
J. Clin. Invest
, vol.123
, pp. 443-454
-
-
Leoni, G.1
-
67
-
-
70349617474
-
Bacterial-modulated host immunity and stem cell activation for gut homeostasis
-
Lee, W.-J. Bacterial-modulated host immunity and stem cell activation for gut homeostasis. Genes Dev. 23, 2260-2265 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 2260-2265
-
-
Lee, W.-J.1
-
68
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in
-
Hochmuth, C. E., Biteau, B., Bohmann, D. & Jasper, H. Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8, 188-199 (2011).
-
(2011)
Drosophila. Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
69
-
-
84888864785
-
Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species
-
Jones, R. M. et al. Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species. EMBO J. 32, 3017-3028 (2013).
-
(2013)
EMBO J
, vol.32
, pp. 3017-3028
-
-
Jones, R.M.1
-
70
-
-
34447296425
-
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
-
Rakoff-Nahoum, S. & Medzhitov, R. Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science 317, 124-127 (2007).
-
(2007)
Science
, vol.317
, pp. 124-127
-
-
Rakoff-Nahoum, S.1
Medzhitov, R.2
-
71
-
-
77953196709
-
ERK activation drives intestinal tumorigenesis in Apcmin/+ mice
-
Lee, S. H. et al. ERK activation drives intestinal tumorigenesis in Apcmin/+ mice. Nature Med. 16, 665-670 (2010).
-
(2010)
Nature Med
, vol.16
, pp. 665-670
-
-
Lee, S.H.1
-
72
-
-
79959944892
-
Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice
-
Vlantis, K. et al. Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice. J. Clin. Invest. 121, 2781-2793 (2011).
-
(2011)
J. Clin. Invest
, vol.121
, pp. 2781-2793
-
-
Vlantis, K.1
-
73
-
-
84872600554
-
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
-
Schwitalla, S. et al. Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell 152, 25-38 (2013).
-
(2013)
Cell
, vol.152
, pp. 25-38
-
-
Schwitalla, S.1
-
74
-
-
36549082403
-
Toll-Like receptor-4 promotes the development of colitis-associated colorectal tumors
-
Fukata, M. et al. Toll-Like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology 133, 1869-1869 (2007).
-
(2007)
Gastroenterology
, vol.133
, pp. 1869-1869
-
-
Fukata, M.1
-
75
-
-
34247175428
-
The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
-
Xiao, H. et al. The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity 26, 461-475 (2007).
-
(2007)
Immunity
, vol.26
, pp. 461-475
-
-
Xiao, H.1
-
76
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
Dupaul-Chicoine, J. et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity 32, 367-378 (2010).
-
(2010)
Immunity
, vol.32
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
-
77
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Hu, B. et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. PNAS 107, 21635-21640 (2010).
-
(2010)
PNAS
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
-
78
-
-
81255189478
-
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis
-
Zaki, M. H. et al. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell 20, 649-660 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 649-660
-
-
Zaki, M.H.1
-
79
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
Normand, S. et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc. Natl Acad. Sci. USA 108, 9601-9606 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 9601-9606
-
-
Normand, S.1
-
80
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-?B signaling
-
Allen, I. C. et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-?B signaling. Immunity 36, 742-754 (2012).
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
-
81
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18
-
Salcedo, R. et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J. Exp. Med. 207, 1625-1636 (2010).
-
(2010)
J. Exp. Med
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
-
82
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Huber, S. et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 491, 259-263 (2012).
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
-
83
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
-
Otte, J.-M., Cario, E. & Podolsky, D. K. Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 126, 1054-1070 (2004).
-
(2004)
Gastroenterology
, vol.126
, pp. 1054-1070
-
-
Otte, J.-M.1
Cario, E.2
Podolsky, D.K.3
-
84
-
-
33645843063
-
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
-
Lotz, M. et al. Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells. J. Exp. Med. 203, 973-984 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 973-984
-
-
Lotz, M.1
-
85
-
-
77954391573
-
Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
-
Vereecke, L. et al. Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. J. Exp. Med. 207, 1513-1523 (2010).
-
(2010)
J. Exp. Med
, vol.207
, pp. 1513-1523
-
-
Vereecke, L.1
-
86
-
-
77958105934
-
MiR-146a mediates protective innate immune tolerance in the neonate intestine
-
Chassin, C. et al. miR-146a mediates protective innate immune tolerance in the neonate intestine. Cell Host Microbe 8, 358-368 (2010).
-
(2010)
Cell Host Microbe
, vol.8
, pp. 358-368
-
-
Chassin, C.1
-
87
-
-
80054842204
-
Constitutive intestinal NF-?B does not trigger destructive inflammation unless accompanied by MAPK activation
-
Guma, M. et al. Constitutive intestinal NF-?B does not trigger destructive inflammation unless accompanied by MAPK activation. J. Exp. Med. 208, 1889-1900 (2011).
-
(2011)
J. Exp. Med
, vol.208
, pp. 1889-1900
-
-
Guma, M.1
-
88
-
-
0034284803
-
Prokaryotic regulation of epithelial responses by inhibition of I?B-? Ubiquitination
-
Neish, A. S. et al. Prokaryotic regulation of epithelial responses by inhibition of I?B-? ubiquitination. Science 289, 1560-1563 (2000).
-
(2000)
Science
, vol.289
, pp. 1560-1563
-
-
Neish, A.S.1
-
89
-
-
59849113820
-
The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation
-
Kumar, A. et al. The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation. J. Immunol. 182, 538-546 (2009).
-
(2009)
J. Immunol
, vol.182
, pp. 538-546
-
-
Kumar, A.1
-
90
-
-
84865298775
-
Dissecting negative regulation of Toll-like receptor signaling
-
Kondo, T., Kawai, T. & Akira, S. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol. 33, 449-458 (2012).
-
(2012)
Trends Immunol
, vol.33
, pp. 449-458
-
-
Kondo, T.1
Kawai, T.2
Akira, S.3
-
91
-
-
84857546470
-
Beyond pattern recognition: Five immune checkpoints for scaling the microbial threat
-
Blander, J. M. & Sander, L. E. Beyond pattern recognition: five immune checkpoints for scaling the microbial threat. Nature Rev. Immunol. 12, 215-225 (2012).
-
(2012)
Nature Rev. Immunol
, vol.12
, pp. 215-225
-
-
Blander, J.M.1
Sander, L.E.2
-
92
-
-
0035881675
-
Cutting edge: Bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
-
Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J. & Madara, J. L. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J. Immunol. 167, 1882-1885 (2001).
-
(2001)
J. Immunol
, vol.167
, pp. 1882-1885
-
-
Gewirtz, A.T.1
Navas, T.A.2
Lyons, S.3
Godowski, P.J.4
Madara, J.L.5
-
93
-
-
26444440067
-
Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation
-
Rhee, S. H. et al. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc. Natl Acad. Sci. USA 102, 13610-13615 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 13610-13615
-
-
Rhee, S.H.1
-
94
-
-
33751551466
-
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
-
Lee, J. et al. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nature Cell Biol. 8, 1327-1336 (2006).
-
(2006)
Nature Cell Biol
, vol.8
, pp. 1327-1336
-
-
Lee, J.1
-
95
-
-
22244465576
-
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-?B activation in muramyl dipeptide recognition
-
Barnich, N., Aguirre, J. E., Reinecker, H.-C., Xavier, R. & Podolsky, D. K. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-?B activation in muramyl dipeptide recognition. J. Cell Biol. 170, 21-26 (2005).
-
(2005)
J. Cell Biol
, vol.170
, pp. 21-26
-
-
Barnich, N.1
Aguirre, J.E.2
Reinecker, H.-C.3
Xavier, R.4
Podolsky, D.K.5
-
96
-
-
84871837817
-
RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition
-
Lipinski, S. et al. RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition. Proc. Natl Acad. Sci. USA 109, 21426-21431 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 21426-21431
-
-
Lipinski, S.1
-
97
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger, P. The danger model: A renewed sense of self. Science 296, 301-305 (2002).
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
98
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander, L. E. et al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 474, 385-389 (2011).
-
(2011)
Nature
, vol.474
, pp. 385-389
-
-
Sander, L.E.1
-
99
-
-
0037340434
-
Angiogenins: A new class of microbicidal proteins involved in innate immunity
-
Hooper, L. V., Stappenbeck, T. S., Hong, C. V. & Gordon, J. I. Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nature Immunol. 4, 269-273 (2003).
-
(2003)
Nature Immunol
, vol.4
, pp. 269-273
-
-
Hooper, L.V.1
Stappenbeck, T.S.2
Hong, C.V.3
Gordon, J.I.4
-
100
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi, K. S. et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307, 731-734 (2005).
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
-
101
-
-
58549111588
-
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
-
Vaishnava, S., Behrendt, C. L., Ismail, A. S., Eckmann, L. & Hooper, L. V. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc. Natl Acad. Sci. USA 105, 20858-20863 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 20858-20863
-
-
Vaishnava, S.1
Behrendt, C.L.2
Ismail, A.S.3
Eckmann, L.4
Hooper, L.V.5
-
102
-
-
79959459365
-
Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-?B pathways in intestinal epithelial cells
-
Bruno, M. E. C., Frantz, A. L., Rogier, E. W., Johansen, F.-E. & Kaetzel, C. S. Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-?B pathways in intestinal epithelial cells. Mucosal Immunol. 4, 468-478 (2011).
-
(2011)
Mucosal Immunol
, vol.4
, pp. 468-478
-
-
Bruno, M.E.C.1
Frantz, A.L.2
Rogier, E.W.3
Johansen, F.-E.4
Kaetzel, C.S.5
-
103
-
-
18244387204
-
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
-
Rimoldi, M. et al. Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nature Immunol. 6, 507-514 (2005).
-
(2005)
Nature Immunol
, vol.6
, pp. 507-514
-
-
Rimoldi, M.1
-
104
-
-
37849032964
-
Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-?
-
Zeuthen, L. H., Fink, L. N. & Frokiaer, H. Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-?. Immunology 123, 197-208 (2008).
-
(2008)
Immunology
, vol.123
, pp. 197-208
-
-
Zeuthen, L.H.1
Fink, L.N.2
Frokiaer, H.3
-
105
-
-
33947573767
-
Epithelial-cell-intrinsic IKK? Expression regulates intestinal immune homeostasis
-
Zaph, C. et al. Epithelial-cell-intrinsic IKK? expression regulates intestinal immune homeostasis. Nature 446, 552-556 (2007).
-
(2007)
Nature
, vol.446
, pp. 552-556
-
-
Zaph, C.1
-
106
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
Atarashi, K. et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 331, 337-341 (2011).
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
-
107
-
-
53349120339
-
Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine
-
Zaph, C. et al. Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine. J. Exp. Med. 205, 2191-2198 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 2191-2198
-
-
Zaph, C.1
-
108
-
-
34250205694
-
Intestinal bacteria trigger T cell-independent immunoglobulin A2 class switching by inducing epithelial-cell secretion of the cytokine APRIL
-
He, B. et al. Intestinal bacteria trigger T cell-independent immunoglobulin A2 class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 26, 812-826 (2007).
-
(2007)
Immunity
, vol.26
, pp. 812-826
-
-
He, B.1
-
109
-
-
34247181001
-
Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI
-
Xu, W. et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nature Immunol. 8, 294-303 (2007).
-
(2007)
Nature Immunol
, vol.8
, pp. 294-303
-
-
Xu, W.1
-
110
-
-
63449112387
-
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis
-
Taylor, B. C. et al. TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J. Exp. Med. 206, 655-667 (2009).
-
(2009)
J. Exp. Med
, vol.206
, pp. 655-667
-
-
Taylor, B.C.1
-
111
-
-
77956112107
-
The puzzle of intestinal lamina propria dendritic cells and macrophages
-
Pabst, O. & Bernhardt, G. The puzzle of intestinal lamina propria dendritic cells and macrophages. Eur. J. Immunol. 40, 2107-2111 (2010).
-
(2010)
Eur. J. Immunol
, vol.40
, pp. 2107-2111
-
-
Pabst, O.1
Bernhardt, G.2
-
112
-
-
70049098070
-
Origin of the lamina propria dendritic cell network
-
Bogunovic, M. et al. Origin of the lamina propria dendritic cell network. Immunity 31, 513-525 (2009).
-
(2009)
Immunity
, vol.31
, pp. 513-525
-
-
Bogunovic, M.1
-
113
-
-
70049099836
-
Intestinal lamina propria dendritic cell subsets have different origin and functions
-
Varol, C. et al. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 31, 502-512 (2009).
-
(2009)
Immunity
, vol.31
, pp. 502-512
-
-
Varol, C.1
-
114
-
-
84856815290
-
Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon
-
Rivollier, A., He, J., Kole, A., Valatas, V. & Kelsall, B. L. Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J. Exp. Med. 209, 139-155 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 139-155
-
-
Rivollier, A.1
He, J.2
Kole, A.3
Valatas, V.4
Kelsall, B.L.5
-
115
-
-
84875830139
-
Intestinal macrophages: Well educated exceptions from the rule
-
Zigmond, E. & Jung, S. Intestinal macrophages: well educated exceptions from the rule. Trends Immunol. 34, 162-168 (2013).
-
(2013)
Trends Immunol
, vol.34
, pp. 162-168
-
-
Zigmond, E.1
Jung, S.2
-
116
-
-
73949107838
-
Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
-
Schulz, O. et al. Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 206, 3101-3114 (2009).
-
(2009)
J. Exp. Med
, vol.206
, pp. 3101-3114
-
-
Schulz, O.1
-
117
-
-
1542618118
-
Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
-
Macpherson, A. J. & Uhr, T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 303, 1662-1665 (2004).
-
(2004)
Science
, vol.303
, pp. 1662-1665
-
-
Macpherson, A.J.1
Uhr, T.2
-
118
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-?- and retinoic acid- dependent mechanism
-
Coombes, J. L. et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-?- and retinoic acid- dependent mechanism. J. Exp. Med. 204, 1757-1764 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
-
119
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun, C.-M. et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204, 1775-1785 (2007).
-
(2007)
J. Exp. Med
, vol.204
, pp. 1775-1785
-
-
Sun, C.-M.1
-
120
-
-
0038264036
-
Selective imprinting of gut-homing T cells by Peyers patch dendritic cells
-
Mora, J. R. et al. Selective imprinting of gut-homing T cells by Peyers patch dendritic cells. Nature 424, 88-93 (2003).
-
(2003)
Nature
, vol.424
, pp. 88-93
-
-
Mora, J.R.1
-
121
-
-
26844538936
-
Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
-
Johansson-Lindbom, B. et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J. Exp. Med. 202, 1063-1073 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1063-1073
-
-
Johansson-Lindbom, B.1
-
122
-
-
5644300399
-
Retinoic acid imprints gut-homing specificity on T cells
-
Iwata, M. et al. Retinoic acid imprints gut-homing specificity on T cells. Immunity 21, 527-538 (2004).
-
(2004)
Immunity
, vol.21
, pp. 527-538
-
-
Iwata, M.1
-
123
-
-
51049092467
-
Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans
-
Jaensson, E. et al. Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. J. Exp. Med. 205, 2139-2149 (2008).
-
(2008)
J. Exp. Med
, vol.205
, pp. 2139-2149
-
-
Jaensson, E.1
-
124
-
-
48849115839
-
Differentiation and homing of IgA-secreting cells
-
Mora, J. R. & von Andrian, U. H. Differentiation and homing of IgA-secreting cells. Mucosal Immunol. 1, 96-109 (2008).
-
(2008)
Mucosal Immunol
, vol.1
, pp. 96-109
-
-
Mora, J.R.1
Von Andrian, U.H.2
-
125
-
-
12244297799
-
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
-
Niess, J. H. et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307, 254-258 (2005).
-
(2005)
Science
, vol.307
, pp. 254-258
-
-
Niess, J.H.1
-
126
-
-
79951772860
-
Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria
-
Hadis, U. et al. Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria. Immunity 34, 237-246 (2011).
-
(2011)
Immunity
, vol.34
, pp. 237-246
-
-
Hadis, U.1
-
127
-
-
70350464351
-
Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
-
Murai, M. et al. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nature Immunol. 10, 1178-1184 (2009).
-
(2009)
Nature Immunol
, vol.10
, pp. 1178-1184
-
-
Murai, M.1
-
128
-
-
84859452120
-
Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis
-
Kayama, H. et al. Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis. Proc. Natl Acad. Sci. USA 109, 5010-5015 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 5010-5015
-
-
Kayama, H.1
-
129
-
-
84856584612
-
Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via ?v?1 integrin
-
Kang, S. et al. Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via ?v?1 integrin. J. Immunol. 188, 1108-1116 (2012).
-
(2012)
J. Immunol
, vol.188
, pp. 1108-1116
-
-
Kang, S.1
-
130
-
-
77951817294
-
IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses
-
Saenz, S. A. et al. IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses. Nature 464, 1362-1366 (2010).
-
(2010)
Nature
, vol.464
, pp. 1362-1366
-
-
Saenz, S.A.1
-
131
-
-
80052582016
-
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
-
Siracusa, M. C. et al. TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature 477, 229-233 (2011).
-
(2011)
Nature
, vol.477
, pp. 229-233
-
-
Siracusa, M.C.1
-
132
-
-
84886630206
-
IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells
-
Saenz, S. A. et al. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J. Exp. Med. 210, 1823-1837 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 1823-1837
-
-
Saenz, S.A.1
-
133
-
-
84890150269
-
Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation
-
Siracusa, M. C. et al. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity 39, 1158-1170 (2013).
-
(2013)
Immunity
, vol.39
, pp. 1158-1170
-
-
Siracusa, M.C.1
-
134
-
-
84859384082
-
Innate lymphoid cells: Emerging insights in development, lineage relationships, and function
-
Spits, H. & Cupedo, T. Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 30, 647-675 (2012).
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 647-675
-
-
Spits, H.1
Cupedo, T.2
-
135
-
-
84862688241
-
Innate lymphoid cells: Critical regulators of allergic inflammation and tissue repair in the lung
-
Monticelli, L. A., Sonnenberg, G. F. & Artis, D. Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung. Curr. Opin. Immunol. 24, 284-289 (2012).
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 284-289
-
-
Monticelli, L.A.1
Sonnenberg, G.F.2
Artis, D.3
-
136
-
-
84874055169
-
TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation
-
Kim, B. S. et al. TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation. Sci. Transl. Med. 5, 170ra16 (2013).
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Kim, B.S.1
-
137
-
-
84867636023
-
Innate lymphoid cells: Balancing immunity, inflammation, and tissue repair in the intestine
-
Tait Wojno, E. D. & Artis, D. Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine. Cell Host Microbe 12, 445-457 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 445-457
-
-
Tait Wojno, E.D.1
Artis, D.2
-
138
-
-
84872968300
-
Innate lymphoid cells - How did we miss them?
-
Walker, J. A., Barlow, J. L. & McKenzie, A. N. J. Innate lymphoid cells - how did we miss them? Nature Rev. Immunol. 13, 75-87 (2013).
-
(2013)
Nature Rev. Immunol
, vol.13
, pp. 75-87
-
-
Walker, J.A.1
Barlow, J.L.2
McKenzie, A.N.J.3
-
139
-
-
84862690161
-
Development and function of intestinal innate lymphoid cells
-
Cherrier, M., Ohnmacht, C., Cording, S. & Eberl, G. Development and function of intestinal innate lymphoid cells. Curr. Opin. Immunol. 24, 277-283 (2012).
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 277-283
-
-
Cherrier, M.1
Ohnmacht, C.2
Cording, S.3
Eberl, G.4
-
140
-
-
84872977452
-
Innate lymphoid cells - A proposal for uniform nomenclature
-
Spits, H. et al. Innate lymphoid cells - a proposal for uniform nomenclature. Nature Rev. Immunol. 13, 145-149 (2013).
-
(2013)
Nature Rev. Immunol
, vol.13
, pp. 145-149
-
-
Spits, H.1
-
141
-
-
85027945857
-
Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
-
Bernink, J. H. et al. Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues. Nature Immunol. 14, 221-229 (2013).
-
(2013)
Nature Immunol
, vol.14
, pp. 221-229
-
-
Bernink, J.H.1
-
142
-
-
84876780238
-
Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-?-producing cells
-
Fuchs, A. et al. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-?-producing cells. Immunity 38, 769-781 (2013).
-
(2013)
Immunity
, vol.38
, pp. 769-781
-
-
Fuchs, A.1
-
143
-
-
75749122181
-
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
-
Moro, K. et al. Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells. Nature 463, 540-544 (2009).
-
(2009)
Nature
, vol.463
, pp. 540-544
-
-
Moro, K.1
-
144
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill, D. R. et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464, 1367-1370 (2010).
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
-
145
-
-
77954926597
-
Systemically dispersed innate IL-13-expressing cells in type 2 immunity
-
Price, A. E. et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc. Natl Acad. Sci. USA 107, 11489-11494 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 11489-11494
-
-
Price, A.E.1
-
146
-
-
85027948313
-
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
-
Monticelli, L. A. et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nature Immunol. 12, 1045-1054 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 1045-1054
-
-
Monticelli, L.A.1
-
147
-
-
79959380307
-
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
-
Chang, Y.-J. et al. Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nature Immunol. 12, 631-638 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 631-638
-
-
Chang, Y.-J.1
-
148
-
-
80054927155
-
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
-
Wilhelm, C. et al. An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nature Immunol. 12, 1071-1077 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 1071-1077
-
-
Wilhelm, C.1
-
149
-
-
84858775590
-
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
-
Halim, T. Y. F., Krau?, R. H., Sun, A. C. & Takei, F. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 36, 451-463 (2012).
-
(2012)
Immunity
, vol.36
, pp. 451-463
-
-
Halim, T.Y.F.1
Krau, R.H.2
Sun, A.C.3
Takei, F.4
-
150
-
-
84867773093
-
The transcription factor GATA3 Is essential for the function of human type 2 innate lymphoid cells
-
Mj?sberg, J. et al. The transcription factor GATA3 Is essential for the function of human type 2 innate lymphoid cells. Immunity 37, 649-659 (2012).
-
(2012)
Immunity
, vol.37
, pp. 649-659
-
-
Mjsberg, J.1
-
151
-
-
0030710079
-
Developing lymph nodes collect, CD4+CD3? LT?+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells
-
Mebius, R. E., Rennert, P. & Weissman, I. L. Developing lymph nodes collect, CD4+CD3? LT?+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 7, 493-504 (1997).
-
(1997)
Immunity
, vol.7
, pp. 493-504
-
-
Mebius, R.E.1
Rennert, P.2
Weissman, I.L.3
-
152
-
-
57449090428
-
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease
-
Zenewicz, L. A. et al. Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity 29, 947-957 (2008).
-
(2008)
Immunity
, vol.29
, pp. 947-957
-
-
Zenewicz, L.A.1
-
153
-
-
78751706261
-
CD4+ lymphoid tissue-inducer cells promote innate immunity in the gut
-
Sonnenberg, G. F., Monticelli, L. A., Elloso, M. M., Fouser, L. A. & Artis, D. CD4+ lymphoid tissue-inducer cells promote innate immunity in the gut. Immunity 34, 122-134 (2011).
-
(2011)
Immunity
, vol.34
, pp. 122-134
-
-
Sonnenberg, G.F.1
Monticelli, L.A.2
Elloso, M.M.3
Fouser, L.A.4
Artis, D.5
-
154
-
-
84861989207
-
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
-
Sonnenberg, G. F. et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 336, 1321-1325 (2012).
-
(2012)
Science
, vol.336
, pp. 1321-1325
-
-
Sonnenberg, G.F.1
-
155
-
-
84865401664
-
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease
-
Hanash, A. M. et al. Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease. Immunity 37, 339-350 (2012).
-
(2012)
Immunity
, vol.37
, pp. 339-350
-
-
Hanash, A.M.1
-
156
-
-
84879571464
-
Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model
-
Kirchberger, S. et al. Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. J. Exp. Med. 210, 917-931 (2013).
-
(2013)
J. Exp. Med
, vol.210
, pp. 917-931
-
-
Kirchberger, S.1
-
157
-
-
73949103213
-
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17
-
Muoz, M. et al. Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J. Exp. Med. 206, 3047-3059 (2009).
-
(2009)
J. Exp. Med
, vol.206
, pp. 3047-3059
-
-
Muoz, M.1
-
158
-
-
77951878587
-
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
-
Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464, 1371-1375 (2010).
-
(2010)
Nature
, vol.464
, pp. 1371-1375
-
-
Buonocore, S.1
-
159
-
-
79958277385
-
IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease
-
Geremia, A. et al. IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease. J. Exp. Med. 208, 1127-1133 (2011).
-
(2011)
J. Exp. Med
, vol.208
, pp. 1127-1133
-
-
Geremia, A.1
-
160
-
-
84866362664
-
IL-1? Mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
-
Coccia, M. et al. IL-1? mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells. J. Exp. Med. 209, 1595-1609 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 1595-1609
-
-
Coccia, M.1
-
161
-
-
79952986650
-
ROR?t+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
-
Sawa, S. et al. ROR?t+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nature Immunol. 12, 320-326 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 320-326
-
-
Sawa, S.1
-
162
-
-
78649360369
-
Regulated expression of nuclear receptor ROR?t confers distinct functional fates to NK cell receptor-expressing ROR?t+ innate lymphocytes
-
Vonarbourg, C. et al. Regulated expression of nuclear receptor ROR?t confers distinct functional fates to NK cell receptor-expressing ROR?t+ innate lymphocytes. Immunity 33, 736-751 (2010).
-
(2010)
Immunity
, vol.33
, pp. 736-751
-
-
Vonarbourg, C.1
-
163
-
-
57449118239
-
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
-
Satoh-Takayama, N. et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008).
-
(2008)
Immunity
, vol.29
, pp. 958-970
-
-
Satoh-Takayama, N.1
-
164
-
-
33646466776
-
MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 TCR and TCR intestinal intraepithelial lymphocytes
-
Yu, Q. et al. MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 TCR and TCR intestinal intraepithelial lymphocytes. J. Immunol. 176, 6180-6185 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 6180-6185
-
-
Yu, Q.1
-
165
-
-
79959664629
-
The light and dark sides of intestinal intraepithelial lymphocytes
-
Cheroutre, H., Lambolez, F. & Mucida, D. The light and dark sides of intestinal intraepithelial lymphocytes. Nature Rev. Immunol. 11, 445-456 (2011).
-
(2011)
Nature Rev. Immunol
, vol.11
, pp. 445-456
-
-
Cheroutre, H.1
Lambolez, F.2
Mucida, D.3
-
166
-
-
84860807200
-
Dynamic migration of intraepithelial lymphocytes requires occludin
-
Edelblum, K. L. et al. Dynamic migration of intraepithelial lymphocytes requires occludin. Proc. Natl Acad. Sci. USA 109, 7097-7102 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 7097-7102
-
-
Edelblum, K.L.1
-
167
-
-
79957701773
-
Intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface
-
Ismail, A. S. et al. intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface. Proc. Natl Acad. Sci. USA 108, 8743-8748 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 8743-8748
-
-
Ismail, A.S.1
-
168
-
-
85027952412
-
Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes
-
Mucida, D. et al. Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nature Immunol. 14, 281-289 (2013).
-
(2013)
Nature Immunol
, vol.14
, pp. 281-289
-
-
Mucida, D.1
-
169
-
-
84871713120
-
Peripheral tissue surveillance and residency by memory T cells
-
Gebhardt, T., Mueller, S. N., Heath, W. R. & Carbone, F. R. Peripheral tissue surveillance and residency by memory T cells. Trends Immunol. 34, 27-32 (2013).
-
(2013)
Trends Immunol
, vol.34
, pp. 27-32
-
-
Gebhardt, T.1
Mueller, S.N.2
Heath, W.R.3
Carbone, F.R.4
-
170
-
-
84872772721
-
Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets
-
Sathaliyawala, T. et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity 38, 187-197 (2013).
-
(2013)
Immunity
, vol.38
, pp. 187-197
-
-
Sathaliyawala, T.1
-
171
-
-
0033151953
-
Mucosal T lymphocyte numbers are selectively reduced in integrin ?E (CD103)-deficient mice
-
Sch?n, M. P. et al. Mucosal T lymphocyte numbers are selectively reduced in integrin ?E (CD103)-deficient mice. J. Immunol. 162, 6641-6649 (1999).
-
(1999)
J. Immunol
, vol.162
, pp. 6641-6649
-
-
Schn, M.P.1
-
172
-
-
19344361971
-
TGF-?-dependent CD103 expression by CD8+ T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease
-
El-Asady, R. et al. TGF-?-dependent CD103 expression by CD8+ T cells promotes selective destruction of the host intestinal epithelium during graft-versus-host disease. J. Exp. Med. 201, 1647-1657 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 1647-1657
-
-
El-Asady, R.1
-
173
-
-
80054897931
-
Mucosal memory CD8+ T cells are selected in the periphery by an MHC class i molecule
-
Huang, Y. et al. Mucosal memory CD8+ T cells are selected in the periphery by an MHC class I molecule. Nature Immunol. 12, 1086-1095 (2011).
-
(2011)
Nature Immunol
, vol.12
, pp. 1086-1095
-
-
Huang, Y.1
-
174
-
-
84860788997
-
Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation
-
Mackay, L. K. et al. Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation. Proc. Natl Acad. Sci. USA 109, 7037-7042 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 7037-7042
-
-
Mackay, L.K.1
-
175
-
-
84869082967
-
A vaccine strategy that protects against genital herpes by establishing local memory T cells
-
Shin, H. & Iwasaki, A. A vaccine strategy that protects against genital herpes by establishing local memory T cells. Nature 491, 463-467 (2012).
-
(2012)
Nature
, vol.491
, pp. 463-467
-
-
Shin, H.1
Iwasaki, A.2
-
176
-
-
79957618772
-
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
-
Hansen, S. G. et al. Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473, 523-527 (2011).
-
(2011)
Nature
, vol.473
, pp. 523-527
-
-
Hansen, S.G.1
-
177
-
-
44349195660
-
The regulation of IgA class switching
-
Cerutti, A. The regulation of IgA class switching. Nature Rev. Immunol. 8, 421-434 (2008).
-
(2008)
Nature Rev. Immunol
, vol.8
, pp. 421-434
-
-
Cerutti, A.1
-
178
-
-
33751223544
-
Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
-
Mora, J. R. et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 314, 1157-1160 (2006).
-
(2006)
Science
, vol.314
, pp. 1157-1160
-
-
Mora, J.R.1
-
179
-
-
0036732753
-
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
-
Litinskiy, M. B. et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nature Immunol. 3, 822-829 (2002).
-
(2002)
Nature Immunol
, vol.3
, pp. 822-829
-
-
Litinskiy, M.B.1
-
180
-
-
12344297875
-
TACI and BAFF-R mediate isotype switching in B cells
-
Castigli, E. et al. TACI and BAFF-R mediate isotype switching in B cells. J. Exp. Med. 201, 35-39 (2005).
-
(2005)
J. Exp. Med
, vol.201
, pp. 35-39
-
-
Castigli, E.1
-
181
-
-
23044443492
-
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
-
Salzer, U. et al. Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans. Nature Genet. 37, 820-828 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 820-828
-
-
Salzer, U.1
-
182
-
-
23044463627
-
TACI is mutant in common variable immunodeficiency and IgA deficiency
-
Castigli, E. et al. TACI is mutant in common variable immunodeficiency and IgA deficiency. Nature Genet. 37, 829-834 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 829-834
-
-
Castigli, E.1
-
183
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003-1007 (2007).
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
-
184
-
-
83255193921
-
Interconversion between intestinal stem cell populations in distinct niches
-
Takeda, N. et al. Interconversion between intestinal stem cell populations in distinct niches. Science 334, 1420-1424 (2011).
-
(2011)
Science
, vol.334
, pp. 1420-1424
-
-
Takeda, N.1
-
185
-
-
84862946094
-
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
-
Yan, K. S. et al. The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proc. Natl Acad. Sci. USA 109, 466-471 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 466-471
-
-
Yan, K.S.1
-
186
-
-
84867660831
-
IFN-? and TNF-?-induced GBP-1 inhibits epithelial cell proliferation through suppression of ?-catenin/TCF signaling
-
Capaldo, C. T. et al. IFN-? and TNF-?-induced GBP-1 inhibits epithelial cell proliferation through suppression of ?-catenin/TCF signaling. Mucosal Immunol. 5, 681-690 (2012).
-
(2012)
Mucosal Immunol
, vol.5
, pp. 681-690
-
-
Capaldo, C.T.1
-
187
-
-
77949937466
-
Interferon-? Regulates intestinal epithelial homeostasis through converging ?-Catenin signaling pathways
-
Nava, P. et al. Interferon-? regulates intestinal epithelial homeostasis through converging ?-catenin signaling pathways. Immunity 32, 392-402 (2010).
-
(2010)
Immunity
, vol.32
, pp. 392-402
-
-
Nava, P.1
-
188
-
-
84889565117
-
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis
-
Alenghat, T. et al. Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis. Nature 504, 153-157 (2013).
-
(2013)
Nature
, vol.504
, pp. 153-157
-
-
Alenghat, T.1
-
189
-
-
30944443377
-
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
-
Blair, S. A., Kane, S. V., Clayburgh, D. R. & Turner, J. R. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab. Invest. 86, 191-201 (2006).
-
(2006)
Lab. Invest
, vol.86
, pp. 191-201
-
-
Blair, S.A.1
Kane, S.V.2
Clayburgh, D.R.3
Turner, J.R.4
-
190
-
-
77950585581
-
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
-
Marchiando, A. M. et al. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J. Cell Biol. 189, 111-126 (2010).
-
(2010)
J. Cell Biol
, vol.189
, pp. 111-126
-
-
Marchiando, A.M.1
-
191
-
-
79952089399
-
Active deformation of apoptotic intestinal epithelial cells with adhesion-restricted polarity contributes to apoptotic clearance
-
Wang, F. et al. Active deformation of apoptotic intestinal epithelial cells with adhesion-restricted polarity contributes to apoptotic clearance. Lab. Invest. 91, 462-471 (2011).
-
(2011)
Lab. Invest
, vol.91
, pp. 462-471
-
-
Wang, F.1
-
192
-
-
84860109015
-
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
-
Eisenhoffer, G. T. et al. Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature 484, 546-549 (2012).
-
(2012)
Nature
, vol.484
, pp. 546-549
-
-
Eisenhoffer, G.T.1
-
193
-
-
0032871326
-
Intestinal permeability test as a predictor of clinical course in Crohns disease
-
DInc, R. et al. Intestinal permeability test as a predictor of clinical course in Crohns disease. Am. J. Gastroenterol. 94, 2956-2960 (1999).
-
(1999)
Am. J. Gastroenterol
, vol.94
, pp. 2956-2960
-
-
Dinc, R.1
-
194
-
-
0027217379
-
Intestinal permeability and the prediction of relapse in Crohns disease
-
Wyatt, J. & Vogelsang, H. Intestinal permeability and the prediction of relapse in Crohns disease. Lancet 341, 1437 (1993).
-
(1993)
Lancet
, vol.341
, pp. 1437
-
-
Wyatt, J.1
Vogelsang, H.2
-
195
-
-
84866523733
-
Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis
-
Khounlotham, M. et al. Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitis. Immunity 37, 563-573 (2012).
-
(2012)
Immunity
, vol.37
, pp. 563-573
-
-
Khounlotham, M.1
-
196
-
-
58649090901
-
Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
-
Su, L. et al. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 136, 551-563 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 551-563
-
-
Su, L.1
|