RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 52, 2012, Pages 21426-21431

  Lipinski, Simone ^a   Grabe, Nils ^a   Jacobs, Gunnar ^a   Billmann Born, Susanne ^a   Till, Andreas ^a,b   Has̈ler, Robert ^a   Aden, Konrad ^a   Paulsen, Maren ^a   Arlt, Alexander ^c   Kraemer, Lars ^a   Hagemann, Nina ^d   Erdmann, Kai Sven ^d   Schreiber, Stefan ^a,c   Rosenstiel, Philip ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Innate immune responses; Intestinal epithelium; Nuclear factor kappaB

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; FRMPD2 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUCINE; MEMBRANE ASSOCIATED ERBB2IP PROTEIN; MEMBRANE PROTEIN; MURAMYL DIPEPTIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PDZ PROTEIN; PDZ PROTEIN 2; PROTEIN; RIPK2 PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTIGEN RECOGNITION; ARTICLE; CELL POLARITY; CROHN DISEASE; DOWN REGULATION; ENTERITIS; EPITHELIUM CELL; GENE STRUCTURE; GENETIC TRUNCATION; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; CACO-2 CELLS; CELL MEMBRANE; CROHN DISEASE; ENTEROCYTES; HEK293 CELLS; HUMANS; MODELS, BIOLOGICAL; MUTANT PROTEINS; NF-KAPPA B; NOD2 SIGNALING ADAPTOR PROTEIN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; REPRODUCIBILITY OF RESULTS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TIGHT JUNCTION PROTEINS;

BACTERIA (MICROORGANISMS);

EID: 84871837817     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209673109     Document Type: Article

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