-
1
-
-
0041837509
-
Trefoil factors: initiators of mucosal healing
-
Taupin D., and Podolsky D.K. Trefoil factors: initiators of mucosal healing. Nat Rev Mol Cell Biol 4 (2003) 721-732
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 721-732
-
-
Taupin, D.1
Podolsky, D.K.2
-
2
-
-
0029828745
-
Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
-
Mashimo H., Wu D.C., Podolsky D.K., et al. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 274 (1996) 262-265
-
(1996)
Science
, vol.274
, pp. 262-265
-
-
Mashimo, H.1
Wu, D.C.2
Podolsky, D.K.3
-
3
-
-
0035821249
-
Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
-
Furuta G.T., Turner J.R., Taylor C.T., et al. Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med 193 (2001) 1027-1034
-
(2001)
J Exp Med
, vol.193
, pp. 1027-1034
-
-
Furuta, G.T.1
Turner, J.R.2
Taylor, C.T.3
-
4
-
-
1542287384
-
Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor
-
Beck P.L., Wong J.F., Li Y., et al. Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor. Gastroenterology 126 (2004) 796-808
-
(2004)
Gastroenterology
, vol.126
, pp. 796-808
-
-
Beck, P.L.1
Wong, J.F.2
Li, Y.3
-
5
-
-
0028360991
-
Trefoil peptides promote epithelial migration through a transforming growth factor β-independent pathway
-
Dignass A., Lynch-Devaney K., Kindon H., et al. Trefoil peptides promote epithelial migration through a transforming growth factor β-independent pathway. J Clin Invest 94 (1994) 376-383
-
(1994)
J Clin Invest
, vol.94
, pp. 376-383
-
-
Dignass, A.1
Lynch-Devaney, K.2
Kindon, H.3
-
6
-
-
0035793372
-
Molecular analysis of commensal host-microbial relationships in the intestine
-
Hooper L.V., Wong M.H., Thelin A., et al. Molecular analysis of commensal host-microbial relationships in the intestine. Science 291 (2001) 881-884
-
(2001)
Science
, vol.291
, pp. 881-884
-
-
Hooper, L.V.1
Wong, M.H.2
Thelin, A.3
-
7
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier R.J., and Podolsky D.K. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448 (2007) 427-434
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
8
-
-
55749096587
-
Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction
-
Cario E. Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction. Curr Opin Gastroenterol 24 (2008) 725-732
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 725-732
-
-
Cario, E.1
-
9
-
-
34548608447
-
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
-
Jin M.S., Kim S.E., Heo J.Y., et al. Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell 130 (2007) 1071-1082
-
(2007)
Cell
, vol.130
, pp. 1071-1082
-
-
Jin, M.S.1
Kim, S.E.2
Heo, J.Y.3
-
10
-
-
0034650930
-
Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors
-
Cario E., Rosenberg I.M., Brandwein S.L., et al. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J Immunol 164 (2000) 966-972
-
(2000)
J Immunol
, vol.164
, pp. 966-972
-
-
Cario, E.1
Rosenberg, I.M.2
Brandwein, S.L.3
-
11
-
-
33947667036
-
Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion
-
Palazzo M., Balsari A., Rossini A., et al. Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol 178 (2007) 4296-4303
-
(2007)
J Immunol
, vol.178
, pp. 4296-4303
-
-
Palazzo, M.1
Balsari, A.2
Rossini, A.3
-
12
-
-
3242692641
-
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
-
Cario E., Gerken G., and Podolsky D.K. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology 127 (2004) 224-238
-
(2004)
Gastroenterology
, vol.127
, pp. 224-238
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
13
-
-
34247235029
-
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
-
Cario E., Gerken G., and Podolsky D.K. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 132 (2007) 1359-1374
-
(2007)
Gastroenterology
, vol.132
, pp. 1359-1374
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
14
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., et al. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118 (2004) 229-241
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
-
15
-
-
29744448927
-
Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases
-
Pierik M., Joossens S., Van Steen K., et al. Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases. Inflamm Bowel Dis 12 (2006) 1-8
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 1-8
-
-
Pierik, M.1
Joossens, S.2
Van Steen, K.3
-
16
-
-
0033454060
-
A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells
-
Itoh H., Beck P.L., Inoue N., et al. A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells. J Clin Invest 104 (1999) 1539-1547
-
(1999)
J Clin Invest
, vol.104
, pp. 1539-1547
-
-
Itoh, H.1
Beck, P.L.2
Inoue, N.3
-
17
-
-
0036134858
-
Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi
-
Wooten R.M., Ma Y., Yoder R.A., et al. Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi. J Immunol 168 (2002) 348-355
-
(2002)
J Immunol
, vol.168
, pp. 348-355
-
-
Wooten, R.M.1
Ma, Y.2
Yoder, R.A.3
-
18
-
-
33646933064
-
TLR1- and TLR6-independent recognition of bacterial lipopeptides
-
Buwitt-Beckmann U., Heine H., Wiesmuller K.H., et al. TLR1- and TLR6-independent recognition of bacterial lipopeptides. J Biol Chem 281 (2006) 9049-9057
-
(2006)
J Biol Chem
, vol.281
, pp. 9049-9057
-
-
Buwitt-Beckmann, U.1
Heine, H.2
Wiesmuller, K.H.3
-
19
-
-
0033134603
-
The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation
-
Taupin D., Wu D.C., Jeon W.K., et al. The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation. J Clin Invest 103 (1999) R31-R38
-
(1999)
J Clin Invest
, vol.103
-
-
Taupin, D.1
Wu, D.C.2
Jeon, W.K.3
-
20
-
-
45149097431
-
Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds
-
Paulsen F.P., Woon C.W., Varoga D., et al. Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds. J Biol Chem 283 (2008) 13418-13427
-
(2008)
J Biol Chem
, vol.283
, pp. 13418-13427
-
-
Paulsen, F.P.1
Woon, C.W.2
Varoga, D.3
-
21
-
-
0034681162
-
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis
-
Taupin D.R., Kinoshita K., and Podolsky D.K. Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci U S A 97 (2000) 799-804
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 799-804
-
-
Taupin, D.R.1
Kinoshita, K.2
Podolsky, D.K.3
-
22
-
-
0034042831
-
Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor
-
Kinoshita K., Taupin D.R., Itoh H., et al. Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor. Mol Cell Biol 20 (2000) 4680-4690
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4680-4690
-
-
Kinoshita, K.1
Taupin, D.R.2
Itoh, H.3
-
23
-
-
26844509194
-
Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro
-
Gustafsson A.C., Kupershmidt I., Edlundh-Rose E., et al. Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro. BMC Cancer 5 (2005) 75
-
(2005)
BMC Cancer
, vol.5
, pp. 75
-
-
Gustafsson, A.C.1
Kupershmidt, I.2
Edlundh-Rose, E.3
-
24
-
-
9444252934
-
Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-κB activation
-
Chang Y.J., Wu M.S., Lin J.T., et al. Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-κB activation. Mol Pharmacol 66 (2004) 1465-1477
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1465-1477
-
-
Chang, Y.J.1
Wu, M.S.2
Lin, J.T.3
-
25
-
-
23844480058
-
Expression of human TFF3 in relation to growth of HT-29 cell subpopulations: involvement of PI3-K but not STAT6
-
Durual S., Blanchard C., Estienne M., et al. Expression of human TFF3 in relation to growth of HT-29 cell subpopulations: involvement of PI3-K but not STAT6. Differentiation 73 (2005) 36-44
-
(2005)
Differentiation
, vol.73
, pp. 36-44
-
-
Durual, S.1
Blanchard, C.2
Estienne, M.3
-
26
-
-
0034972162
-
A silencer inhibitor confers specific expression of intestinal trefoil factor in gobletlike cell lines
-
Iwakiri D., and Podolsky D.K. A silencer inhibitor confers specific expression of intestinal trefoil factor in gobletlike cell lines. Am J Physiol Gastrointest Liver Physiol 280 (2001) G1114-G1123
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.280
-
-
Iwakiri, D.1
Podolsky, D.K.2
-
27
-
-
54349106465
-
Barrier-protective function of intestinal epithelial Toll-like receptor 2
-
Cario E. Barrier-protective function of intestinal epithelial Toll-like receptor 2. Mucosal Immunol Suppl 1 (2008) S62-S66
-
(2008)
Mucosal Immunol
, Issue.SUPPL. 1
-
-
Cario, E.1
-
28
-
-
0035053278
-
Keratinocyte growth factor promotes goblet cell differentiation through regulation of goblet cell silencer inhibitor
-
Iwakiri D., and Podolsky D.K. Keratinocyte growth factor promotes goblet cell differentiation through regulation of goblet cell silencer inhibitor. Gastroenterology 120 (2001) 1372-1380
-
(2001)
Gastroenterology
, vol.120
, pp. 1372-1380
-
-
Iwakiri, D.1
Podolsky, D.K.2
-
29
-
-
0036340041
-
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
-
Katz J.P., Perreault N., Goldstein B.G., et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129 (2002) 2619-2628
-
(2002)
Development
, vol.129
, pp. 2619-2628
-
-
Katz, J.P.1
Perreault, N.2
Goldstein, B.G.3
-
30
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
Yang Q., Bermingham N.A., Finegold M.J., et al. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294 (2001) 2155-2158
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
-
31
-
-
26944474424
-
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation
-
Shroyer N.F., Wallis D., Venken K.J., et al. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev 19 (2005) 2412-2417
-
(2005)
Genes Dev
, vol.19
, pp. 2412-2417
-
-
Shroyer, N.F.1
Wallis, D.2
Venken, K.J.3
-
32
-
-
11844279745
-
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
-
Pull S.L., Doherty J.M., Mills J.C., et al. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc Natl Acad Sci U S A 102 (2005) 99-104
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 99-104
-
-
Pull, S.L.1
Doherty, J.M.2
Mills, J.C.3
-
33
-
-
0028080029
-
Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract
-
Housley R.M., Morris C.F., Boyle W., et al. Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract. J Clin Invest 94 (1994) 1764-1777
-
(1994)
J Clin Invest
, vol.94
, pp. 1764-1777
-
-
Housley, R.M.1
Morris, C.F.2
Boyle, W.3
-
34
-
-
0036796060
-
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
-
Tebbutt N.C., Giraud A.S., Inglese M., et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nat Med 8 (2002) 1089-1097
-
(2002)
Nat Med
, vol.8
, pp. 1089-1097
-
-
Tebbutt, N.C.1
Giraud, A.S.2
Inglese, M.3
-
35
-
-
33645237577
-
Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex
-
Twiddy D., Cohen G.M., Macfarlane M., et al. Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex. J Biol Chem 281 (2006) 3876-3888
-
(2006)
J Biol Chem
, vol.281
, pp. 3876-3888
-
-
Twiddy, D.1
Cohen, G.M.2
Macfarlane, M.3
-
36
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E., and Podolsky D.K. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 68 (2000) 7010-7017
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
37
-
-
34249677845
-
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
-
Kanzler H., Barrat F.J., Hessel E.M., et al. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists. Nat Med 13 (2007) 552-559
-
(2007)
Nat Med
, vol.13
, pp. 552-559
-
-
Kanzler, H.1
Barrat, F.J.2
Hessel, E.M.3
|