-
1
-
-
33645128917
-
Progression of airway dysplasia and C-reactive protein in smokers at high risk of lung cancer
-
Sin D.D., Man S.F., McWilliams A., et al. Progression of airway dysplasia and C-reactive protein in smokers at high risk of lung cancer. Am J Respir Crit Care Med 173 (2006) 535-539
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 535-539
-
-
Sin, D.D.1
Man, S.F.2
McWilliams, A.3
-
2
-
-
33747481384
-
Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice
-
Rao V.P., Poutahidis T., Ge Z., et al. Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice. Cancer Res 66 (2006) 7395-7400
-
(2006)
Cancer Res
, vol.66
, pp. 7395-7400
-
-
Rao, V.P.1
Poutahidis, T.2
Ge, Z.3
-
3
-
-
33644533143
-
A prospective study of serum C-reactive protein and colorectal cancer risk in men
-
Gunter M.J., Stolzenberg-Solomon R., Cross A.J., et al. A prospective study of serum C-reactive protein and colorectal cancer risk in men. Cancer Res 66 (2006) 2483-2487
-
(2006)
Cancer Res
, vol.66
, pp. 2483-2487
-
-
Gunter, M.J.1
Stolzenberg-Solomon, R.2
Cross, A.J.3
-
4
-
-
36549075344
-
-
Surveillance, Epidemiology, and End Results (SEER) Program and the National Center for Health Statistics. Available at: http://seer.cancer.gov/cgi-bin/twbsearch?pr-seer&query-colorect& template-%2Fsearch%2Findex.htm.
-
-
-
-
5
-
-
3042599473
-
Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation
-
Itzkowitz S.H., and Yio X. Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol 287 (2004) G7-G17
-
(2004)
Am J Physiol
, vol.287
-
-
Itzkowitz, S.H.1
Yio, X.2
-
6
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: a meta-analysis
-
Eaden J.A., Abrams K.R., and Mayberry J.F. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 48 (2001) 526-535
-
(2001)
Gut
, vol.48
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
7
-
-
10744221150
-
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
-
Rutter M., Saunders B., Wilkinson K., et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 126 (2004) 451-459
-
(2004)
Gastroenterology
, vol.126
, pp. 451-459
-
-
Rutter, M.1
Saunders, B.2
Wilkinson, K.3
-
8
-
-
34848893583
-
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study
-
Gupta R.B., Harpaz N., Itzkowitz S., et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 133 (2007) 1099-1105
-
(2007)
Gastroenterology
, vol.133
, pp. 1099-1105
-
-
Gupta, R.B.1
Harpaz, N.2
Itzkowitz, S.3
-
9
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten F.R., Eckmann L., Greten T.F., et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118 (2004) 285-296
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
10
-
-
13844310155
-
Sporadic colorectal cancer-role of the commensal microbiota
-
Hope M.E., Hold G.L., Kain R., et al. Sporadic colorectal cancer-role of the commensal microbiota. FEMS Microbiol Lett 244 (2005) 1-7
-
(2005)
FEMS Microbiol Lett
, vol.244
, pp. 1-7
-
-
Hope, M.E.1
Hold, G.L.2
Kain, R.3
-
11
-
-
33847037554
-
Extracellular superoxide production by Enterococcus faecalis promotes chromosomal instability in mammalian cells
-
Wang X., and Huycke M.M. Extracellular superoxide production by Enterococcus faecalis promotes chromosomal instability in mammalian cells. Gastroenterology 132 (2007) 551-561
-
(2007)
Gastroenterology
, vol.132
, pp. 551-561
-
-
Wang, X.1
Huycke, M.M.2
-
12
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon R.K., Tonkonogy S., Schultz M., et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66 (1998) 5224-5231
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
-
13
-
-
0035866802
-
Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice
-
Kado S., Uchida K., Funabashi H., et al. Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice. Cancer Res 61 (2001) 2395-2398
-
(2001)
Cancer Res
, vol.61
, pp. 2395-2398
-
-
Kado, S.1
Uchida, K.2
Funabashi, H.3
-
14
-
-
0035424901
-
Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu M.T., Vora P., Faure E., et al. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol 167 (2001) 1609-1616
-
(2001)
J Immunol
, vol.167
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
-
15
-
-
1842583729
-
Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
-
Otte J.M., Cario E., and Podolsky D.K. Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 126 (2004) 1054-1070
-
(2004)
Gastroenterology
, vol.126
, pp. 1054-1070
-
-
Otte, J.M.1
Cario, E.2
Podolsky, D.K.3
-
16
-
-
0036080092
-
Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation
-
Hausmann M., Kiessling S., Mestermann S., et al. Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. Gastroenterology 122 (2002) 1987-2000
-
(2002)
Gastroenterology
, vol.122
, pp. 1987-2000
-
-
Hausmann, M.1
Kiessling, S.2
Mestermann, S.3
-
17
-
-
3242692641
-
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
-
Cario E., Gerken G., and Podolsky D.K. Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology 127 (2004) 224-238
-
(2004)
Gastroenterology
, vol.127
, pp. 224-238
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
18
-
-
33748271299
-
Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine
-
Fukata M., Chen A., Klepper A., et al. Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine. Gastroenterology 131 (2006) 862-877
-
(2006)
Gastroenterology
, vol.131
, pp. 862-877
-
-
Fukata, M.1
Chen, A.2
Klepper, A.3
-
19
-
-
20444432334
-
Toll-like receptors on tumor cells facilitate evasion of immune surveillance
-
Huang B., Zhao J., Li H., et al. Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res 65 (2005) 5009-5014
-
(2005)
Cancer Res
, vol.65
, pp. 5009-5014
-
-
Huang, B.1
Zhao, J.2
Li, H.3
-
20
-
-
19044390942
-
The role of prostaglandins and other eicosanoids in the gastrointestinal tract
-
Wang D., Mann J.R., and DuBois R.N. The role of prostaglandins and other eicosanoids in the gastrointestinal tract. Gastroenterology 128 (2005) 1445-1461
-
(2005)
Gastroenterology
, vol.128
, pp. 1445-1461
-
-
Wang, D.1
Mann, J.R.2
DuBois, R.N.3
-
21
-
-
13744254574
-
Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention
-
Dannenberg A.J., Lippman S.M., Mann J.R., et al. Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention. J Clin Oncol 23 (2005) 254-266
-
(2005)
J Clin Oncol
, vol.23
, pp. 254-266
-
-
Dannenberg, A.J.1
Lippman, S.M.2
Mann, J.R.3
-
22
-
-
0029942998
-
Promotion of colorectal neoplasia in experimental murine ulcerative colitis
-
Okayasu I., Ohkusa T., Kajiura K., et al. Promotion of colorectal neoplasia in experimental murine ulcerative colitis. Gut 39 (1996) 87-92
-
(1996)
Gut
, vol.39
, pp. 87-92
-
-
Okayasu, I.1
Ohkusa, T.2
Kajiura, K.3
-
23
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
Fukata M., Michelsen K.S., Eri R., et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol 288 (2005) G1055-G1065
-
(2005)
Am J Physiol
, vol.288
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
-
24
-
-
0034052970
-
Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, B-catenin and p53 expression and the role of inflammation
-
Cooper H.S., Murthy S., Kido K., et al. Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, B-catenin and p53 expression and the role of inflammation. Carcinogenesis 21 (2000) 757-768
-
(2000)
Carcinogenesis
, vol.21
, pp. 757-768
-
-
Cooper, H.S.1
Murthy, S.2
Kido, K.3
-
25
-
-
0033997088
-
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
-
Morteau O., Morham S.G., Sellon R., et al. Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2. J Clin Invest 105 (2000) 469-478
-
(2000)
J Clin Invest
, vol.105
, pp. 469-478
-
-
Morteau, O.1
Morham, S.G.2
Sellon, R.3
-
26
-
-
0035424901
-
Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide
-
Abreu M.T., Vora P., Faure E., et al. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide. J Immunol 167 (2001) 1609-1616
-
(2001)
J Immunol
, vol.167
, pp. 1609-1616
-
-
Abreu, M.T.1
Vora, P.2
Faure, E.3
-
27
-
-
0037036469
-
TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells
-
Abreu M.T., Arnold E.T., Thomas L.S., et al. TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J Biol Chem 277 (2002) 20431-20437
-
(2002)
J Biol Chem
, vol.277
, pp. 20431-20437
-
-
Abreu, M.T.1
Arnold, E.T.2
Thomas, L.S.3
-
28
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E., and Podolsky D.K. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 68 (2000) 7010-7017
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
29
-
-
29744461120
-
Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice
-
Suzuki R., Kohno H., Sugie S., et al. Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice. Carcinogenesis 27 (2006) 162-169
-
(2006)
Carcinogenesis
, vol.27
, pp. 162-169
-
-
Suzuki, R.1
Kohno, H.2
Sugie, S.3
-
30
-
-
2442600137
-
Diagnosis and management of dysplasia in patients with inflammatory bowel diseases
-
Itzkowitz S.H., and Harpaz N. Diagnosis and management of dysplasia in patients with inflammatory bowel diseases. Gastroenterology 126 (2004) 1634-1648
-
(2004)
Gastroenterology
, vol.126
, pp. 1634-1648
-
-
Itzkowitz, S.H.1
Harpaz, N.2
-
31
-
-
33744938436
-
Activation of smooth muscle and myenteric plexus cells of jejunum via Toll-like receptor 4
-
Rumio C., Besusso D., Arnaboldi F., et al. Activation of smooth muscle and myenteric plexus cells of jejunum via Toll-like receptor 4. J Cell Physiol 208 (2006) 47-54
-
(2006)
J Cell Physiol
, vol.208
, pp. 47-54
-
-
Rumio, C.1
Besusso, D.2
Arnaboldi, F.3
-
32
-
-
0033568358
-
Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice
-
Suganuma M., Okabe S., Marino M.W., et al. Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice. Cancer Res 59 (1999) 4516-4518
-
(1999)
Cancer Res
, vol.59
, pp. 4516-4518
-
-
Suganuma, M.1
Okabe, S.2
Marino, M.W.3
-
33
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
-
Castellone M.D., Teramoto H., Williams B.O., et al. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 310 (2005) 1504-1510
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
-
34
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
Pai R., Soreghan B., Szabo I.L., et al. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 8 (2002) 289-293
-
(2002)
Nat Med
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
-
35
-
-
0041816104
-
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
-
Buchanan F.G., Wang D., Bargiacchi F., et al. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 278 (2003) 35451-35457
-
(2003)
J Biol Chem
, vol.278
, pp. 35451-35457
-
-
Buchanan, F.G.1
Wang, D.2
Bargiacchi, F.3
-
36
-
-
0141593676
-
Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin
-
Shao J., Lee S.B., Guo H., et al. Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulin. Cancer Res 63 (2003) 5218-5223
-
(2003)
Cancer Res
, vol.63
, pp. 5218-5223
-
-
Shao, J.1
Lee, S.B.2
Guo, H.3
-
37
-
-
19944432973
-
Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands
-
Moraitis D., Du B., De Lorenzo M.S., et al. Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer Res 65 (2005) 664-670
-
(2005)
Cancer Res
, vol.65
, pp. 664-670
-
-
Moraitis, D.1
Du, B.2
De Lorenzo, M.S.3
-
38
-
-
0034977290
-
Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells
-
Kawahara T., Teshima S., Oka A., et al. Type I Helicobacter pylori lipopolysaccharide stimulates Toll-like receptor 4 and activates mitogen oxidase 1 in gastric pit cells. Infect Immun 69 (2001) 4382-4389
-
(2001)
Infect Immun
, vol.69
, pp. 4382-4389
-
-
Kawahara, T.1
Teshima, S.2
Oka, A.3
-
39
-
-
0037033364
-
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4
-
Termeer C., Benedix F., Sleeman J., et al. Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 195 (2002) 99-111
-
(2002)
J Exp Med
, vol.195
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
-
40
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
de Visser K.E., Eichten A., and Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6 (2006) 24-37
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 24-37
-
-
de Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
41
-
-
11144353913
-
Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1
-
Subbaramaiah K., Yoshimatsu K., Scherl E., et al. Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1. J Biol Chem 279 (2004) 12647-12658
-
(2004)
J Biol Chem
, vol.279
, pp. 12647-12658
-
-
Subbaramaiah, K.1
Yoshimatsu, K.2
Scherl, E.3
-
42
-
-
33644857709
-
Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha
-
Otani T., Yamaguchi K., Scherl E., et al. Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha. Am J Physiol 290 (2006) G361-G368
-
(2006)
Am J Physiol
, vol.290
-
-
Otani, T.1
Yamaguchi, K.2
Scherl, E.3
-
43
-
-
33846017279
-
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury
-
Brown S.L., Riehl T.E., Walker M.R., et al. Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury. J Clin Invest 117 (2007) 258-269
-
(2007)
J Clin Invest
, vol.117
, pp. 258-269
-
-
Brown, S.L.1
Riehl, T.E.2
Walker, M.R.3
-
44
-
-
12644261426
-
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells
-
Coffey R.J., Hawkey C.J., Damstrup L., et al. Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc Natl Acad Sci U S A 94 (1997) 657-662
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 657-662
-
-
Coffey, R.J.1
Hawkey, C.J.2
Damstrup, L.3
-
45
-
-
25144490062
-
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands
-
Kohno H., Suzuki R., Sugie S., et al. Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. BMC Cancer 5 (2005) 46
-
(2005)
BMC Cancer
, vol.5
, pp. 46
-
-
Kohno, H.1
Suzuki, R.2
Sugie, S.3
-
46
-
-
33645097021
-
A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylat e (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling
-
Ii M., Matsunaga N., Hazeki K., et al. A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylat e (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling. Mol Pharmacol 69 (2006) 1288-1295
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1288-1295
-
-
Ii, M.1
Matsunaga, N.2
Hazeki, K.3
-
47
-
-
33748180713
-
Celecoxib for the prevention of colorectal adenomatous polyps
-
Arber N., Eagle C.J., Spicak J., et al. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med 355 (2006) 885-895
-
(2006)
N Engl J Med
, vol.355
, pp. 885-895
-
-
Arber, N.1
Eagle, C.J.2
Spicak, J.3
-
48
-
-
33748196958
-
Celecoxib for the prevention of sporadic colorectal adenomas
-
Bertagnolli M.M., Eagle C.J., Zauber A.G., et al. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med 355 (2006) 873-884
-
(2006)
N Engl J Med
, vol.355
, pp. 873-884
-
-
Bertagnolli, M.M.1
Eagle, C.J.2
Zauber, A.G.3
|