-
1
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
Strober, W., Fuss, I. & Mannon, P. The fundamental basis of inflammatory bowel disease. J. Clin. Invest. 117, 514-521 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
2
-
-
79959201412
-
Human nutrition, the gut microbiome and the immune system
-
Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L.&Gordon, J. I. Human nutrition, the gut microbiome and the immune system. Nature 474, 327-336 (2011).
-
(2011)
Nature
, vol.474
, pp. 327-336
-
-
Kau, A.L.1
Ahern, P.P.2
Griffin, N.W.3
Goodman, A.L.4
Gordon, J.I.5
-
3
-
-
77952316009
-
Inflammatory bowel disease
-
Kaser, A., Zeissig, S. & Blumberg, R. S. Inflammatory bowel disease. Annu. Rev. Immunol. 28, 573-621 (2010).
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 573-621
-
-
Kaser, A.1
Zeissig, S.2
Blumberg, R.S.3
-
4
-
-
79952929840
-
Gene-environment interactions in chronic inflammatory disease
-
Renz, H. et al. Gene-environment interactions in chronic inflammatory disease. Nature Immunol. 12, 273-277 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 273-277
-
-
Renz, H.1
-
5
-
-
84857437426
-
Minireview: Epigenetics of obesity and diabetes in humans
-
Slomko, H., Heo, H. J. & Einstein, F. H. Minireview: Epigenetics of obesity and diabetes in humans. Endocrinology 153, 1025-1030 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 1025-1030
-
-
Slomko, H.1
Heo, H.J.2
Einstein, F.H.3
-
6
-
-
80053030747
-
Allergic asthma: Influence of genetic and environmental factors
-
Mukherjee, A. B. & Zhang, Z. Allergic asthma: influence of genetic and environmental factors. J. Biol. Chem. 286, 32883-32889 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32883-32889
-
-
Mukherjee, A.B.1
Zhang, Z.2
-
7
-
-
84876402979
-
Challenges in IBD research: Update on progress and prioritization of the CCFA's research agenda
-
Denson, L. A. et al. Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda. Inflamm. Bowel Dis. 19, 677-682 (2013).
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 677-682
-
-
Denson, L.A.1
-
8
-
-
84867658789
-
Intestinal commensal microbes as immune modulators
-
Ivanov, I. I. & Honda, K. Intestinal commensal microbes as immune modulators. Cell Host Microbe 12, 496-508 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 496-508
-
-
Ivanov, I.I.1
Honda, K.2
-
9
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
Cadwell, K. et al. Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell 141, 1135-1145 (2010).
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
-
10
-
-
84862862332
-
Epithelial antimicrobial defence of the skin and intestine
-
Gallo, R. L.&Hooper, L. V. Epithelial antimicrobial defence of the skin and intestine. Nature Rev. Immunol. 12, 503-516 (2012).
-
(2012)
Nature Rev. Immunol.
, vol.12
, pp. 503-516
-
-
Gallo, R.L.1
Hooper, L.V.2
-
11
-
-
44349132270
-
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
-
Artis, D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nature Rev. Immunol. 8, 411-420 (2008).
-
(2008)
Nature Rev. Immunol.
, vol.8
, pp. 411-420
-
-
Artis, D.1
-
12
-
-
84862060628
-
Metaboloepigenetics: Interrelationships between energymetabolismand epigenetic control of gene expression
-
Donohoe, D. R. & Bultman, S. J. Metaboloepigenetics: interrelationships between energymetabolismand epigenetic control of gene expression. J. Cell. Physiol. 227, 3169-3177 (2012).
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 3169-3177
-
-
Donohoe, D.R.1
Bultman, S.J.2
-
13
-
-
21744435965
-
Controlling nuclear receptors: The circular logic of cofactor cycles
-
Perissi, V. & Rosenfeld, M. G. Controlling nuclear receptors: the circular logic of cofactor cycles. Nature Rev. Mol. Cell Biol. 6, 542-554 (2005).
-
(2005)
Nature Rev. Mol. Cell Biol.
, vol.6
, pp. 542-554
-
-
Perissi, V.1
Rosenfeld, M.G.2
-
14
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
Haberland, M., Montgomery, R. L. & Olson, E. N. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nature Rev. Genet. 10, 32-42 (2009).
-
(2009)
Nature Rev. Genet.
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
15
-
-
78349260122
-
Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery
-
Kim, G. W., Gocevski, G., Wu, C. J. & Yang, X. J. Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery. Int. J. Cell Biol. 2010, 632739 (2010).
-
(2010)
Int. J. Cell Biol. 2
, vol.10
, pp. 632739
-
-
Kim, G.W.1
Gocevski, G.2
Wu, C.J.3
Yang, X.J.4
-
16
-
-
34548456881
-
Dietary histone deacetylase inhibitors: From cells to mice to man
-
Dashwood, R. H. & Ho, E. Dietary histone deacetylase inhibitors: from cells to mice to man. Semin. Cancer Biol. 17, 363-369 (2007).
-
(2007)
Semin. Cancer Biol.
, vol.17
, pp. 363-369
-
-
Dashwood, R.H.1
Ho, E.2
-
17
-
-
84867652835
-
Requirement for the histone deacetylaseHdac3for the inflammatory gene expression program in macrophages
-
Chen, X. et al. Requirement for the histone deacetylaseHdac3for the inflammatory gene expression program in macrophages. Proc. Natl Acad. Sci. USA 109, E2865-E2874 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
-
-
Chen, X.1
-
18
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary, C. et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-840 (2009).
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
-
19
-
-
84873571381
-
Nuclear receptor co-repressors are required for the histonedeacetylase activity ofHDAC3 in vivo
-
You, S. H. et al. Nuclear receptor co-repressors are required for the histonedeacetylase activity ofHDAC3 in vivo. Nature Struct. Mol. Biol. 20, 182-187 (2013).
-
(2013)
Nature Struct. Mol. Biol.
, vol.20
, pp. 182-187
-
-
You, S.H.1
-
20
-
-
57749195091
-
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
-
Alenghat, T. et al. Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature 456, 997-1000 (2008).
-
(2008)
Nature
, vol.456
, pp. 997-1000
-
-
Alenghat, T.1
-
21
-
-
0036161439
-
Enzymatic activity associated with class IIHDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR
-
Fischle, W. et al. Enzymatic activity associated with class IIHDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Mol. Cell 9, 45-57 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 45-57
-
-
Fischle, W.1
-
22
-
-
55849084700
-
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice
-
Montgomery, R. L. et al. Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice. J. Clin. Invest. 118, 3588-3597 (2008).
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3588-3597
-
-
Montgomery, R.L.1
-
23
-
-
79952529158
-
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
-
Feng, D. et al. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science 331, 1315-1319 (2011).
-
(2011)
Science
, vol.331
, pp. 1315-1319
-
-
Feng, D.1
-
24
-
-
82955247088
-
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
-
Mullican, S. E. et al. Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev. 25, 2480-2488 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 2480-2488
-
-
Mullican, S.E.1
-
25
-
-
11844279745
-
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
-
Pull, S. L., Doherty, J. M., Mills, J. C., Gordon, J. I. & Stappenbeck, T. S. Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury. Proc. Natl Acad. Sci. USA 102, 99-104 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 99-104
-
-
Pull, S.L.1
Doherty, J.M.2
Mills, J.C.3
Gordon, J.I.4
Stappenbeck, T.S.5
-
26
-
-
84874688283
-
Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells
-
Diehl, G. E. et al. Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells. Nature 494, 116-120 (2013).
-
(2013)
Nature
, vol.494
, pp. 116-120
-
-
Diehl, G.E.1
-
27
-
-
77956569409
-
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis
-
Garrett, W. S. et al. Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis. Cell Host Microbe 8, 292-300 (2010).
-
(2010)
Cell Host Microbe
, vol.8
, pp. 292-300
-
-
Garrett, W.S.1
-
28
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav, E. et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145, 745-757 (2011).
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
-
29
-
-
84863436944
-
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il102/2 mice
-
Devkota, S. et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il102/2 mice. Nature 487, 104-108 (2012).
-
(2012)
Nature
, vol.487
, pp. 104-108
-
-
Devkota, S.1
-
30
-
-
84872688583
-
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFNc-dependent elimination of Paneth cells
-
Raetz,M. et al. Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFNc-dependent elimination of Paneth cells. Nature Immunol. 14, 136-142 (2013).
-
(2013)
Nature Immunol.
, vol.14
, pp. 136-142
-
-
Raetz, M.1
-
31
-
-
33748713890
-
UniFrac-an online tool for comparing microbial community diversity in a phylogenetic context
-
Lozupone, C., Hamady, M. & Knight, R. UniFrac-an online tool for comparing microbial community diversity in a phylogenetic context. BMC Bioinformatics 7, 371 (2006).
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 371
-
-
Lozupone, C.1
Hamady, M.2
Knight, R.3
-
32
-
-
0037031856
-
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
-
Madison, B. B. et al. Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J. Biol. Chem. 277, 33275-33283 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33275-33283
-
-
Madison, B.B.1
-
33
-
-
4043059169
-
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
-
El Marjou, F. et al. Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis 39, 186-193 (2004).
-
(2004)
Genesis
, vol.39
, pp. 186-193
-
-
El Marjou, F.1
-
34
-
-
33845432928
-
Adjusting batch effects in microarray expressiondata usingempiricalBayesmethods
-
Johnson, W. E., Li, C. & Rabinovic, A. Adjusting batch effects in microarray expressiondata usingempiricalBayesmethods. Biostatistics 8,118-127(2007).
-
(2007)
Biostatistics
, vol.8
, pp. 118-127
-
-
Johnson, W.E.1
Li, C.2
Rabinovic, A.3
-
35
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
36
-
-
62349130698
-
Ultrafastandmemory-efficient alignmentof shortDNAsequencestothehumangenome
-
Langmead,B.,Trapnell, C.,Pop,M.&Salzberg,S. L.Ultrafastandmemory- efficient alignmentof shortDNAsequencestothehumangenome.GenomeBiol.10,R25(2009).
-
(2009)
GenomeBiol.
, vol.10
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
37
-
-
77952243141
-
QIIME allows analysis of high-throughput community sequencing data
-
Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nature Methods 7, 335-336 (2010).
-
(2010)
Nature Methods
, vol.7
, pp. 335-336
-
-
Caporaso, J.G.1
-
38
-
-
29144464937
-
UniFrac: A new phylogenetic method for comparing microbial communities
-
Lozupone, C. & Knight, R. UniFrac: a new phylogenetic method for comparing microbial communities. Appl. Environ. Microbiol. 71, 8228-8235 (2005).
-
(2005)
Appl. Environ. Microbiol.
, vol.71
, pp. 8228-8235
-
-
Lozupone, C.1
Knight, R.2
-
39
-
-
0034252293
-
Secretion of microbicidal a-defensins by intestinal Paneth cells in response to bacteria
-
Ayabe, T. et al. Secretion of microbicidal a-defensins by intestinal Paneth cells in response to bacteria. Nature Immunol. 1, 113-118 (2000).
-
(2000)
Nature Immunol.
, vol.1
, pp. 113-118
-
-
Ayabe, T.1
|