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Volumn 8, Issue 12, 2006, Pages 1327-1336

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 9;

EID: 33751551466     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1500     Document Type: Article
Times cited : (518)

References (46)
  • 1
    • 0034780639 scopus 로고    scopus 로고
    • Interaction of bacterial pathogens with polarized epithelium
    • Kazmierczak, B. I., Mostov, K. & Engel, J. N. Interaction of bacterial pathogens with polarized epithelium. Annu. Rev. Microbiol. 55, 407-435 (2001).
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 407-435
    • Kazmierczak, B.I.1    Mostov, K.2    Engel, J.N.3
  • 3
    • 0036831301 scopus 로고    scopus 로고
    • Critical role of NF-κB and stress-activated protein kinases in steroid unresponsiveness
    • Bantel, H., Schmitz, M. L., Raible, A., Gregor, M. & Schulze-Osthoff, K. Critical role of NF-κB and stress-activated protein kinases in steroid unresponsiveness. FASEB. J. 16, 1832-1834 (2002).
    • (2002) FASEB. J. , vol.16 , pp. 1832-1834
    • Bantel, H.1    Schmitz, M.L.2    Raible, A.3    Gregor, M.4    Schulze-Osthoff, K.5
  • 4
    • 10744233159 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
    • Rachmilewitz, D. et al. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology 126, 520-528 (2004).
    • (2004) Gastroenterology , vol.126 , pp. 520-528
    • Rachmilewitz, D.1
  • 5
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S. & Medzhitov, R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241 (2004).
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 6
    • 0036241068 scopus 로고    scopus 로고
    • Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis
    • Rachmilewitz, D. et al. Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis. Gastroenterology 122, 1428-1441 (2002).
    • (2002) Gastroenterology , vol.122 , pp. 1428-1441
    • Rachmilewitz, D.1
  • 7
    • 20244372724 scopus 로고    scopus 로고
    • Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
    • Fukata, M. et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 288, G1055-G1065 (2005).
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.288
    • Fukata, M.1
  • 8
    • 14644403009 scopus 로고    scopus 로고
    • Toll-like receptor 9-induced type I IFN protects mice from experimental colitis
    • Katakura, K. et al. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J. Clin. Invest. 115, 695-702 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 695-702
    • Katakura, K.1
  • 9
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira, S. & Hemmi, H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85, 85-95 (2003).
    • (2003) Immunol. Lett. , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 10
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S. & Takeda, K. Toll-like receptor signalling. Nature Rev. Immunol. 4, 499-511 (2004).
    • (2004) Nature Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 11
    • 0036144233 scopus 로고    scopus 로고
    • Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium
    • Cario, E. et al. Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium. Am. J. Pathol. 160, 165-173 (2002).
    • (2002) Am. J. Pathol. , vol.160 , pp. 165-173
    • Cario, E.1
  • 12
    • 0037446528 scopus 로고    scopus 로고
    • Strategic compartmentalization of Toll-like receptor 4 in the mouse gut
    • Ortega-Cava, C. F. et al. Strategic compartmentalization of Toll-like receptor 4 in the mouse gut. J. Immunol. 170, 3977-3985 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 3977-3985
    • Ortega-Cava, C.F.1
  • 13
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed tlr5 to induce epithelial proinflammatory gene expression
    • Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J. & Madara, J. L. Cutting edge: Bacterial flagellin activates basolaterally expressed tlr5 to induce epithelial proinflammatory gene expression. J. Immunol. 167, 1882-1885 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 14
    • 0038604293 scopus 로고    scopus 로고
    • Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-κB-independent pathway
    • Akhtar, M., Watson, J. L., Nazli, A. & McKay, D. M. Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-κB-independent pathway. FASEB J. 17, 1319-1321 (2003).
    • (2003) FASEB J. , vol.17 , pp. 1319-1321
    • Akhtar, M.1    Watson, J.L.2    Nazli, A.3    McKay, D.M.4
  • 15
    • 1842583729 scopus 로고    scopus 로고
    • Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells
    • Otte, J. M., Cario, E. & Podolsky, D. K. Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. Gastroenterology 126, 1054-1070 (2004).
    • (2004) Gastroenterology , vol.126 , pp. 1054-1070
    • Otte, J.M.1    Cario, E.2    Podolsky, D.K.3
  • 16
    • 22344440495 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium
    • Pedersen, G., Andresen, L., Matthiessen, M. W., Rask-Madsen, J. & Brynskov, J. Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium. Clin. Exp. Immunol. 141, 298-306 (2005).
    • (2005) Clin. Exp. Immunol. , vol.141 , pp. 298-306
    • Pedersen, G.1    Andresen, L.2    Matthiessen, M.W.3    Rask-Madsen, J.4    Brynskov, J.5
  • 17
    • 0024462586 scopus 로고
    • Intestinal permeability in patients with Crohn's disease and their healthy relatives
    • Katz, K. D. et al. Intestinal permeability in patients with Crohn's disease and their healthy relatives. Gastroenterology 97, 927-931 (1989).
    • (1989) Gastroenterology , vol.97 , pp. 927-931
    • Katz, K.D.1
  • 18
    • 0025314386 scopus 로고
    • Cellular basis for defective electrolyte transport in inflamed human colon
    • Sandle, G. I. et al. Cellular basis for defective electrolyte transport in inflamed human colon. Gastroenterology 99, 97-105 (1990).
    • (1990) Gastroenterology , vol.99 , pp. 97-105
    • Sandle, G.I.1
  • 19
    • 10744219675 scopus 로고    scopus 로고
    • TLR9 signals after translocating from the ER to CpG DNA in the lysosome
    • Latz, E. et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunol. 5, 190-198 (2004).
    • (2004) Nature Immunol. , vol.5 , pp. 190-198
    • Latz, E.1
  • 20
    • 3142697714 scopus 로고    scopus 로고
    • TLR9 is localized in the endoplasmic reticulum prior to stimulation
    • Leifer, C. A. et al. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J. Immunol. 173, 1179-1183 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 1179-1183
    • Leifer, C.A.1
  • 21
    • 27944453599 scopus 로고    scopus 로고
    • Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
    • Okabe, Y., Kawane, K., Akira, S., Taniguchi, T. & Nagata, S. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med. 202, 1333-1339 (2005).
    • (2005) J. Exp. Med. , vol.202 , pp. 1333-1339
    • Okabe, Y.1    Kawane, K.2    Akira, S.3    Taniguchi, T.4    Nagata, S.5
  • 22
    • 0347624589 scopus 로고    scopus 로고
    • Dual effects of IκB kinase β-mediated phosphorylation on p105 Fate: SCF(β-TrCP)-dependent degradation and SCF(β-TrCP)- independent processing
    • Cohen, S., Achbert-Weiner, H. & Ciechanover, A. Dual effects of IκB kinase β-mediated phosphorylation on p105 Fate: SCF(β-TrCP)-dependent degradation and SCF(β-TrCP)-independent processing. Mol. Cell. Biol. 24, 475-486 (2004).
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 475-486
    • Cohen, S.1    Achbert-Weiner, H.2    Ciechanover, A.3
  • 23
    • 6344264987 scopus 로고    scopus 로고
    • Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of NF-κB1 p105
    • Beinke, S., Robinson, M. J., Hugunin, M. & Ley, S. C. Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of NF-κB1 p105. Mol. Cell. Biol. 24, 9658-9667 (2004).
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9658-9667
    • Beinke, S.1    Robinson, M.J.2    Hugunin, M.3    Ley, S.C.4
  • 24
    • 0037349601 scopus 로고    scopus 로고
    • NF-κB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase
    • Waterfield, M. R., Zhang, M., Norman, L. P. & Sun, S. C. NF-κB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase. Mol. Cell 11, 685-694 (2003).
    • (2003) Mol. Cell , vol.11 , pp. 685-694
    • Waterfield, M.R.1    Zhang, M.2    Norman, L.P.3    Sun, S.C.4
  • 25
    • 20244364236 scopus 로고    scopus 로고
    • Wnt signalling induces maturation of Paneth cells in intestinal crypts
    • van Es, J. H. et al. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nature Cell Biol. 7, 381-386 (2005).
    • (2005) Nature Cell Biol. , vol.7 , pp. 381-386
    • van Es, J.H.1
  • 26
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper, H. S., Murthy, S. N., Shah, R. S. & Sedergran, D. J. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab. Invest. 69, 238-249 (1993).
    • (1993) Lab. Invest. , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 28
    • 26444440067 scopus 로고    scopus 로고
    • Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation
    • Rhee, S. H. et al. Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc. Nat Acad. Sci. USA 102, 13610-13615 (2005).
    • (2005) Proc. Nat Acad. Sci. USA , vol.102 , pp. 13610-13615
    • Rhee, S.H.1
  • 29
    • 2542510727 scopus 로고    scopus 로고
    • Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection
    • Schmausser, B. et al. Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection. Clin. Exp. Immunol. 136, 521-526 (2004).
    • (2004) Clin. Exp. Immunol. , vol.136 , pp. 521-526
    • Schmausser, B.1
  • 30
    • 33746960721 scopus 로고    scopus 로고
    • A critical role for endocytosis in Wnt signaling
    • Blitzer, J. T. & Nusse, R. A critical role for endocytosis in Wnt signaling. BMC. Cell Biol. 7, 28 (2006).
    • (2006) BMC. Cell Biol. , vol.7 , pp. 28
    • Blitzer, J.T.1    Nusse, R.2
  • 31
    • 0033917216 scopus 로고    scopus 로고
    • The subapical compartment and its role in intracellular trafficking and cell polarity
    • Van, I. S. C., Maier, O., Van Der Wouden, J. M. & Hoekstra, D. The subapical compartment and its role in intracellular trafficking and cell polarity. J. Cell Physiol. 184, 151-160 (2000).
    • (2000) J. Cell Physiol. , vol.184 , pp. 151-160
    • Van, I.S.C.1    Maier, O.2    Van Der Wouden, J.M.3    Hoekstra, D.4
  • 32
    • 0000752197 scopus 로고
    • Junctional complexes in various epithelia
    • Farquhar, M. G. & Palade, G. E. Junctional complexes in various epithelia. J. Cell Biol. 17, 375-412 (1963).
    • (1963) J. Cell Biol. , vol.17 , pp. 375-412
    • Farquhar, M.G.1    Palade, G.E.2
  • 33
    • 0038112098 scopus 로고    scopus 로고
    • NF-κB1 p105 negatively regulates TPL-2 MEK kinase activity
    • Beinke, S. et al. NF-κB1 p105 negatively regulates TPL-2 MEK kinase activity. Mol. Cell Biol. 23, 4739-4752 (2003).
    • (2003) Mol. Cell Biol. , vol.23 , pp. 4739-4752
    • Beinke, S.1
  • 34
    • 20144373683 scopus 로고    scopus 로고
    • Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation
    • Shang, F. et al. Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. J. Biol. Chem. 280, 20365-20374 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 20365-20374
    • Shang, F.1
  • 35
    • 0034284803 scopus 로고    scopus 로고
    • Prokaryotic regulation of epithelial responses by inhibition of IκBα ubiquitination
    • Neish, A. S. et al. Prokaryotic regulation of epithelial responses by inhibition of IκBα ubiquitination. Science 289, 1560-1563 (2000).
    • (2000) Science , vol.289 , pp. 1560-1563
    • Neish, A.S.1
  • 36
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-a and RelA
    • Kelly, D. et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-a and RelA. Nature Immunol. 5, 104-112 (2004).
    • (2004) Nature Immunol. , vol.5 , pp. 104-112
    • Kelly, D.1
  • 37
    • 0027968034 scopus 로고
    • Comparative molecular biology of lambdoid phages
    • Campbell, A. Comparative molecular biology of lambdoid phages. Annu. Rev. Microbiol. 48, 193-222 (1994).
    • (1994) Annu. Rev. Microbiol. , vol.48 , pp. 193-222
    • Campbell, A.1
  • 38
    • 0026566361 scopus 로고
    • The Rex system of bacteriophage lambda: Tolerance and altruistic cell death
    • Parma, D. H. et al. The Rex system of bacteriophage lambda: Tolerance and altruistic cell death. Genes Dev. 6, 497-510 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 497-510
    • Parma, D.H.1
  • 39
    • 0025292766 scopus 로고
    • λ-prophage induction in repair-deficient and wild type E. coli strains by γ-rays and heavy ions
    • Bonev, M. N., Kozubek, S., Krasavin, E. A. & Amirtajev, K. G. λ-prophage induction in repair-deficient and wild type E. coli strains by γ-rays and heavy ions. Int. J. Radiat. Biol. 57, 993-1005 (1990).
    • (1990) Int. J. Radiat. Biol. , vol.57 , pp. 993-1005
    • Bonev, M.N.1    Kozubek, S.2    Krasavin, E.A.3    Amirtajev, K.G.4
  • 40
    • 0038651180 scopus 로고    scopus 로고
    • Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
    • Lee, J. et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7. Proc. Natl Acad. Sci. USA 100, 6646-6651 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 6646-6651
    • Lee, J.1
  • 41
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten, F. R. et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118, 285-296 (2004).
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1
  • 43
    • 0033669743 scopus 로고    scopus 로고
    • TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide
    • Lee, J., Mira-Arbibe, L. & Ulevitch, R. J. TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide. J. Leukoc. Biol. 68, 909-915 (2000).
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 909-915
    • Lee, J.1    Mira-Arbibe, L.2    Ulevitch, R.J.3
  • 44
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium
    • O'Neil, D. A. et al. Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium. J. Immunol. 163, 6718-6724 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 6718-6724
    • O'Neil, D.A.1
  • 45
    • 1342303735 scopus 로고    scopus 로고
    • Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray
    • Bozdech, Z. et al. Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray. Genome Biol 4, R9 (2003).
    • (2003) Genome Biol , vol.4
    • Bozdech, Z.1
  • 46
    • 0038486795 scopus 로고    scopus 로고
    • Spotted long oligonucleotide arrays for human gene expression ana sis
    • Barczak, A. et al. Spotted long oligonucleotide arrays for human gene expression ana sis. Genome Res 13, 1775-1785 (2003).
    • (2003) Genome Res , vol.13 , pp. 1775-1785
    • Barczak, A.1


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