The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

Cell Metabolism

Volumn 15, Issue 6, 2012, Pages 838-847

  Cantó, Carles ^a,e   Houtkooper, Riekelt H ^a,f   Pirinen, Eija ^a,b   Youn, Dou Y ^c   Oosterveer, Maaike H ^a   Cen, Yana ^c   Fernandez Marcos, Pablo J ^a   Yamamoto, Hiroyasu ^a   Andreux, Pénélope A ^a   Cettour Rose, Philippe ^a   Gademann, Karl ^d   Rinsch, Chris ^a   Schoonjans, Kristina ^a   Sauve, Anthony A ^c   Auwerx, Johan ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF BASEL   (Switzerland)

^e NESTLÉ RESEARCH CENTER   (Switzerland)

^f ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE RIBOSIDE; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN 1; SIRTUIN 3;

AEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL FUNCTION; DIET SUPPLEMENTATION; ENERGY EXPENDITURE; GENE FUNCTION; GENE SILENCING; LIFESPAN; LIPID DIET; MAMMAL CELL; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SKELETAL MUSCLE; YEAST;

ACETYLATION; ADIPOSE TISSUE, BROWN; ANIMALS; BRAIN; DIET, HIGH-FAT; DIETARY SUPPLEMENTS; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; HEK293 CELLS; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLE, SKELETAL; NAD; NIACINAMIDE; OBESITY; ORGAN SPECIFICITY; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NICOTINIC; SIRTUIN 1; SIRTUIN 3; SUPEROXIDE DISMUTASE; WEIGHT GAIN;

MAMMALIA;

EID: 84862022077     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.04.022     Document Type: Article

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