Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling

Journal of Neuroscience Research

Volumn 89, Issue 11, 2011, Pages 1723-1736

  Guo, Wenjing ^a,b   Qian, Lei ^b   Zhang, Jing ^b   Zhang, Wei ^b   Morrison, Alastair ^c   Hayes, Philip ^c   Wilson, Steve ^c   Chen, Tongsheng ^a   Zhao, Jie ^b  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b GLAXOSMITHKLINE   (China)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid; Dendrites; Neurotoxicity; Phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; S6 KINASE; SIRTUIN 1; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DENDRITE; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; MOUSE; NERVE CELL; NERVE FIBER GROWTH; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; MICE; MICE, TRANSGENIC; NEURITES; NEURONS; SIGNAL TRANSDUCTION; SIRTUIN 1; TOR SERINE-THREONINE KINASES;

EID: 80052645243     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22725     Document Type: Article

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