메뉴 건너뛰기




Volumn 7, Issue 10, 2012, Pages

SIRT1 Regulates Dendritic Development in Hippocampal Neurons

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; HISTONE DEACETYLASE; PROTEIN; RESVERATROL; ROCK PROTEIN; SIRTUIN 1; UNCLASSIFIED DRUG;

EID: 84867131638     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047073     Document Type: Article
Times cited : (69)

References (53)
  • 2
    • 69249235740 scopus 로고    scopus 로고
    • Calorie restriction and the exercise of chromatin
    • Vaquero A, Reinberg D, (2009) Calorie restriction and the exercise of chromatin. Genes & Dev 23: 1849-1869.
    • (2009) Genes & Dev , vol.23 , pp. 1849-1869
    • Vaquero, A.1    Reinberg, D.2
  • 3
    • 4944245398 scopus 로고    scopus 로고
    • Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
    • Vaquero A, Scher M, Lee D, Erdjument-Bromage H, Tempst P, et al. (2004) Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell 16: 93-105.
    • (2004) Mol Cell , vol.16 , pp. 93-105
    • Vaquero, A.1    Scher, M.2    Lee, D.3    Erdjument-Bromage, H.4    Tempst, P.5
  • 5
    • 55749095213 scopus 로고    scopus 로고
    • Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
    • Hisahara S, Chiba S, Matsumoto H, Tanno M, Yagi H, et al. (2008) Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. PNAS 105: 15599-15604.
    • (2008) PNAS , vol.105 , pp. 15599-15604
    • Hisahara, S.1    Chiba, S.2    Matsumoto, H.3    Tanno, M.4    Yagi, H.5
  • 6
    • 33751113602 scopus 로고    scopus 로고
    • Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction
    • Haigis MC, Guarente LP, (2006) Mammalian sirtuins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 20: 2913-2921.
    • (2006) Genes Dev , vol.20 , pp. 2913-2921
    • Haigis, M.C.1    Guarente, L.P.2
  • 7
    • 34447308268 scopus 로고    scopus 로고
    • SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
    • Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, et al. (2007) SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 26: 3169-3179.
    • (2007) EMBO J , vol.26 , pp. 3169-3179
    • Kim, D.1    Nguyen, M.D.2    Dobbin, M.M.3    Fischer, A.4    Sananbenesi, F.5
  • 8
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • Araki T, Sasaki Y, Milbrandt J, (2004) Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305: 1010-1013.
    • (2004) Science , vol.305 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 9
    • 45849121349 scopus 로고    scopus 로고
    • Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
    • Pallàs M, Pizarro JG, Gutierrez-Cuesta J, Crespo-Biel N, Alvira D, et al. (2008) Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience 154: 1388-1397.
    • (2008) Neuroscience , vol.154 , pp. 1388-1397
    • Pallàs, M.1    Pizarro, J.G.2    Gutierrez-Cuesta, J.3    Crespo-Biel, N.4    Alvira, D.5
  • 10
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao J, Wang W-Y, Mao Y-W, Gräff J, Guan J-S, et al. (2010) A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466: 1105-1109.
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.-Y.2    Mao, Y.-W.3    Gräff, J.4    Guan, J.-S.5
  • 11
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • Michán S, Li Y, Chou MM-H, Parrella E, Ge H, et al. (2010) SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci 30: 9695-9707.
    • (2010) J Neurosci , vol.30 , pp. 9695-9707
    • Michán, S.1    Li, Y.2    Chou, M.M.-H.3    Parrella, E.4    Ge, H.5
  • 12
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
    • Marambaud P, Zhao H, Davies P, (2005) Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem 280: 37377-37382.
    • (2005) J Biol Chem , vol.280 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 13
    • 84878091489 scopus 로고    scopus 로고
    • Program No 6409 2010 Neuroscience Meeting Planner San Diego, CA: Society for Neuroscience, 2010. OASIS web site. Available
    • Allard CA, Inestrosa NC, Codocedo JF, Varela-Nallar L (2010) SIRT1 protein modulates dendritic arborization in hippocampal neurons. Program No 6409 2010 Neuroscience Meeting Planner San Diego, CA: Society for Neuroscience, 2010. OASIS web site. Available:http://www.abstractsonline.com/Plan/ViewAbstract.aspx?mID=2554&sKey=f3ce95ee-02ad-4c1f-8871-c673e6f6e717&cKey=d366ca02-fb95-4a6a-ac13-73c8c91ceac8&mKey=%7bE5D5C83F-CE2D-4D71-9DD6-FC7231E090FB%7d#. Accessed 13 September 2012.
    • (2010) SIRT1 protein modulates dendritic arborization in hippocampal neurons
    • Allard, C.A.1    Inestrosa, N.C.2    Codocedo, J.F.3    Varela-Nallar, L.4
  • 14
    • 35549008884 scopus 로고    scopus 로고
    • SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
    • Mattagajasingh I, Kim C-S, Naqvi A, Yamamori T, Hoffman T a, et al. (2007) SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase. PNAS 104: 14855-14860.
    • (2007) PNAS , vol.104 , pp. 14855-14860
    • Mattagajasingh, I.1    Kim, C.-S.2    Naqvi, A.3    Yamamori, T.4    Hoffman, T.5
  • 15
    • 0017350927 scopus 로고
    • Rat hippocampal neurons in dispersed cell culture
    • Banker GA, Cowan WM, (1977) Rat hippocampal neurons in dispersed cell culture. Brain Res 126: 397-42.
    • (1977) Brain Res , vol.126 , pp. 342-397
    • Banker, G.A.1    Cowan, W.M.2
  • 16
    • 0344806277 scopus 로고    scopus 로고
    • Fast, convenient, and effective method to transiently transfect primary hippocampal neurons
    • Köhrmann M, Haubensak W, Hemraj I, Kaether C, Lessmann VJ, et al. (1999) Fast, convenient, and effective method to transiently transfect primary hippocampal neurons. J Neurosci Res 58: 831-835.
    • (1999) J Neurosci Res , vol.58 , pp. 831-835
    • Köhrmann, M.1    Haubensak, W.2    Hemraj, I.3    Kaether, C.4    Lessmann, V.J.5
  • 17
    • 28844467909 scopus 로고    scopus 로고
    • Peroxisomal proliferation protects from beta-amyloid neurodegeneration
    • Santos MJ, Quintanilla RA, Toro A, Grandy R, Dinamarca MC, et al. (2005) Peroxisomal proliferation protects from beta-amyloid neurodegeneration. J Biol Chem 280: 41057-41068.
    • (2005) J Biol Chem , vol.280 , pp. 41057-41068
    • Santos, M.J.1    Quintanilla, R.A.2    Toro, A.3    Grandy, R.4    Dinamarca, M.C.5
  • 18
    • 77249136019 scopus 로고    scopus 로고
    • Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease
    • Dinamarca MC, Sagal JP, Quintanilla RA, Godoy JA, Arrázola MS, et al. (2010) Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease. Mol Neurodegener 5: 4.
    • (2010) Mol Neurodegener , vol.5 , pp. 4
    • Dinamarca, M.C.1    Sagal, J.P.2    Quintanilla, R.A.3    Godoy, J.A.4    Arrázola, M.S.5
  • 19
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T, (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 20
    • 34249108600 scopus 로고    scopus 로고
    • Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons
    • Farías GG, Vallés AS, Colombres M, Godoy JA, Toledo EM, et al. (2007) Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons. J Neurosci 27: 5313-5325.
    • (2007) J Neurosci , vol.27 , pp. 5313-5325
    • Farías, G.G.1    Vallés, A.S.2    Colombres, M.3    Godoy, J.A.4    Toledo, E.M.5
  • 21
    • 33749522711 scopus 로고    scopus 로고
    • Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95
    • Charych EI, Akum BF, Goldberg JS, Jörnsten RJ, Rongo C, et al. (2006) Activity-independent regulation of dendrite patterning by postsynaptic density protein PSD-95. J Neurosci 26: 10164-10176.
    • (2006) J Neurosci , vol.26 , pp. 10164-10176
    • Charych, E.I.1    Akum, B.F.2    Goldberg, J.S.3    Jörnsten, R.J.4    Rongo, C.5
  • 22
    • 36248935670 scopus 로고    scopus 로고
    • Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription
    • Ghosh HS, Spencer JV, Ng B, McBurney MW, Robbins PD, (2007) Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription. Biochem J 408: 105-111.
    • (2007) Biochem J , vol.408 , pp. 105-111
    • Ghosh, H.S.1    Spencer, J.V.2    Ng, B.3    McBurney, M.W.4    Robbins, P.D.5
  • 23
    • 58149339917 scopus 로고    scopus 로고
    • Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity
    • Pfister JA, Ma C, Morrison BE, D'Mello SR, (2008) Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity. PloS One 3: e4090.
    • (2008) PloS One , vol.3
    • Pfister, J.A.1    Ma, C.2    Morrison, B.E.3    D'Mello, S.R.4
  • 24
    • 66749102871 scopus 로고    scopus 로고
    • Histone H3-K56 acetylation is important for genomic stability in mammals
    • Yuan J, Pu M, Zhang Z, Lou Z, (2009) Histone H3-K56 acetylation is important for genomic stability in mammals. Cell cycle 8: 1747-1753.
    • (2009) Cell Cycle , vol.8 , pp. 1747-1753
    • Yuan, J.1    Pu, M.2    Zhang, Z.3    Lou, Z.4
  • 25
    • 65549113750 scopus 로고    scopus 로고
    • CBP/p300-mediated acetylation of histone H3 on lysine 56
    • Das C, Lucia MS, Hansen KC, Tyler JK, (2009) CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 459: 113-117.
    • (2009) Nature , vol.459 , pp. 113-117
    • Das, C.1    Lucia, M.S.2    Hansen, K.C.3    Tyler, J.K.4
  • 26
    • 0036467369 scopus 로고    scopus 로고
    • The JNK signal transduction pathway
    • Weston CR, Davis RJ, (2002) The JNK signal transduction pathway. Curr Opin Genet Dev 12: 14-21.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 14-21
    • Weston, C.R.1    Davis, R.J.2
  • 27
    • 0031956449 scopus 로고    scopus 로고
    • Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway
    • Kita Y, Kimura KD, Kobayashi M, Ihara S, Kaibuchi K, et al. (1998) Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. J Cell Sci 111: 907-915.
    • (1998) J Cell Sci , vol.111 , pp. 907-915
    • Kita, Y.1    Kimura, K.D.2    Kobayashi, M.3    Ihara, S.4    Kaibuchi, K.5
  • 28
    • 67650136764 scopus 로고    scopus 로고
    • Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons
    • Farías GG, Alfaro IE, Cerpa W, Grabowski CP, Godoy JA, et al. (2009) Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons. J Biol Chem 284: 15857-15866.
    • (2009) J Biol Chem , vol.284 , pp. 15857-15866
    • Farías, G.G.1    Alfaro, I.E.2    Cerpa, W.3    Grabowski, C.P.4    Godoy, J.A.5
  • 29
    • 0034017744 scopus 로고    scopus 로고
    • Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases
    • Ishizaki T, Uehata M, Tamechika I, Keel J, Nonomura K, et al. (2000) Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol 57: 976-983.
    • (2000) Mol Pharmacol , vol.57 , pp. 976-983
    • Ishizaki, T.1    Uehata, M.2    Tamechika, I.3    Keel, J.4    Nonomura, K.5
  • 30
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P, (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 31
    • 79958753913 scopus 로고    scopus 로고
    • The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ
    • Grassie ME, Moffat LD, Walsh MP, MacDonald JA, (2011) The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ. Arch Biochem Biophys 510: 147-159.
    • (2011) Arch Biochem Biophys , vol.510 , pp. 147-159
    • Grassie, M.E.1    Moffat, L.D.2    Walsh, M.P.3    MacDonald, J.A.4
  • 32
    • 34249825465 scopus 로고    scopus 로고
    • Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons
    • Yamashita K, Kotani Y, Nakajima Y, Shimazawa M, Yoshimura S, et al. (2007) Fasudil, a Rho kinase (ROCK) inhibitor, protects against ischemic neuronal damage in vitro and in vivo by acting directly on neurons. Brain Res 1154: 215-224.
    • (2007) Brain Res , vol.1154 , pp. 215-224
    • Yamashita, K.1    Kotani, Y.2    Nakajima, Y.3    Shimazawa, M.4    Yoshimura, S.5
  • 33
    • 34249933552 scopus 로고    scopus 로고
    • Anatomical and physiological plasticity of dendritic spines
    • Alvarez VA, Sabatini BL, (2007) Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci 30: 79-97.
    • (2007) Annu Rev Neurosci , vol.30 , pp. 79-97
    • Alvarez, V.A.1    Sabatini, B.L.2
  • 34
    • 0026734317 scopus 로고
    • Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation
    • Harris KM, Jensen FE, Tsao B, (1992) Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. J Neurosci 12: 2685-2705.
    • (1992) J Neurosci , vol.12 , pp. 2685-2705
    • Harris, K.M.1    Jensen, F.E.2    Tsao, B.3
  • 35
    • 5344281149 scopus 로고    scopus 로고
    • Multiple functions for the cadherin/catenin complex during neuronal development
    • Yu X, Malenka RC, (2004) Multiple functions for the cadherin/catenin complex during neuronal development. Neuropharmacology 47: 779-786.
    • (2004) Neuropharmacology , vol.47 , pp. 779-786
    • Yu, X.1    Malenka, R.C.2
  • 36
    • 0033761838 scopus 로고    scopus 로고
    • Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines
    • Rao A, Craig AM, (2000) Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines. Hippocampus 10: 527-541.
    • (2000) Hippocampus , vol.10 , pp. 527-541
    • Rao, A.1    Craig, A.M.2
  • 37
    • 3843136369 scopus 로고    scopus 로고
    • A morphological correlate of synaptic scaling in visual cortex
    • Wallace W, Bear MF, (2004) A morphological correlate of synaptic scaling in visual cortex. J Neurosci 24: 6928-6938.
    • (2004) J Neurosci , vol.24 , pp. 6928-6938
    • Wallace, W.1    Bear, M.F.2
  • 38
    • 50249109475 scopus 로고    scopus 로고
    • Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens
    • Shen H, Sesack SR, Toda S, Kalivas PW, (2008) Automated quantification of dendritic spine density and spine head diameter in medium spiny neurons of the nucleus accumbens. Brain Struct Funct 213: 149-157.
    • (2008) Brain Struct Funct , vol.213 , pp. 149-157
    • Shen, H.1    Sesack, S.R.2    Toda, S.3    Kalivas, P.W.4
  • 39
    • 0035252823 scopus 로고    scopus 로고
    • The role of Notch and Rho GTPase signaling in the control of dendritic development
    • Redmond L, Ghosh A, (2001) The role of Notch and Rho GTPase signaling in the control of dendritic development. Curr Opin Neurobiol 11: 111-117.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 111-117
    • Redmond, L.1    Ghosh, A.2
  • 40
    • 11844304062 scopus 로고    scopus 로고
    • The role of the Rho GTPases in neuronal development
    • Govek E-E, Newey SE, Van Aelst L, (2005) The role of the Rho GTPases in neuronal development. Genes & Dev 19: 1-49.
    • (2005) Genes & Dev , vol.19 , pp. 1-49
    • Govek, E.-E.1    Newey, S.E.2    van Aelst, L.3
  • 41
    • 9444242736 scopus 로고    scopus 로고
    • Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
    • Kimura K, Ito M, Amano M, Chihara K, Fukata Y, et al. (1996) Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245-248.
    • (1996) Science , vol.273 , pp. 245-248
    • Kimura, K.1    Ito, M.2    Amano, M.3    Chihara, K.4    Fukata, Y.5
  • 42
    • 0033615977 scopus 로고    scopus 로고
    • Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
    • Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, et al. (1999) Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol 147: 1023-1038.
    • (1999) J Cell Biol , vol.147 , pp. 1023-1038
    • Kawano, Y.1    Fukata, Y.2    Oshiro, N.3    Amano, M.4    Nakamura, T.5
  • 43
    • 14644421534 scopus 로고    scopus 로고
    • Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models
    • Patel NV, Gordon MN, Connor KE, Good RA, Engelman RW, et al. (2005) Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models. Neurobiol Aging 26: 995-1000.
    • (2005) Neurobiol Aging , vol.26 , pp. 995-1000
    • Patel, N.V.1    Gordon, M.N.2    Connor, K.E.3    Good, R.A.4    Engelman, R.W.5
  • 44
    • 0033566286 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease
    • Duan W, Mattson MP, (1999) Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J Neurosci Res 57: 195-206.
    • (1999) J Neurosci Res , vol.57 , pp. 195-206
    • Duan, W.1    Mattson, M.P.2
  • 45
    • 16844375290 scopus 로고    scopus 로고
    • Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
    • Parker JA, Arango M, Abderrahmane S, Lambert E, Tourette C, et al. (2005) Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat Genet 37: 349-350.
    • (2005) Nat Genet , vol.37 , pp. 349-350
    • Parker, J.A.1    Arango, M.2    Abderrahmane, S.3    Lambert, E.4    Tourette, C.5
  • 46
    • 33746824192 scopus 로고    scopus 로고
    • Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
    • Qin W, Yang T, Ho L, Zhao Z, Wang J, et al. (2006) Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281: 21745-21754.
    • (2006) J Biol Chem , vol.281 , pp. 21745-21754
    • Qin, W.1    Yang, T.2    Ho, L.3    Zhao, Z.4    Wang, J.5
  • 47
    • 79951686964 scopus 로고    scopus 로고
    • The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations
    • Bonda DJ, Lee H-G, Camins A, Pallàs M, Casadesus G, et al. (2011) The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol 10: 275-279.
    • (2011) Lancet Neurol , vol.10 , pp. 275-279
    • Bonda, D.J.1    Lee, H.-G.2    Camins, A.3    Pallàs, M.4    Casadesus, G.5
  • 48
    • 13644271368 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling
    • Inestrosa NC, Godoy JA, Quintanilla RA, Koenig CS, Bronfman M, (2005) Peroxisome proliferator-activated receptor gamma is expressed in hippocampal neurons and its activation prevents beta-amyloid neurodegeneration: role of Wnt signaling. Exp Cell Res 304: 91-104.
    • (2005) Exp Cell Res , vol.304 , pp. 91-104
    • Inestrosa, N.C.1    Godoy, J.A.2    Quintanilla, R.A.3    Koenig, C.S.4    Bronfman, M.5
  • 49
    • 18544372447 scopus 로고    scopus 로고
    • Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity
    • Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, et al. (2005) Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. J Cell Biol 169: 331-339.
    • (2005) J Cell Biol , vol.169 , pp. 331-339
    • Smith, W.W.1    Norton, D.D.2    Gorospe, M.3    Jiang, H.4    Nemoto, S.5
  • 50
    • 36348974168 scopus 로고    scopus 로고
    • The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation
    • Zhang J, (2007) The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation. J Biol Chem 282: 34356-34364.
    • (2007) J Biol Chem , vol.282 , pp. 34356-34364
    • Zhang, J.1
  • 51
    • 45549096918 scopus 로고    scopus 로고
    • SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons
    • Li Y, Xu W, McBurney MW, Longo VD, (2008) SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab 8: 38-48.
    • (2008) Cell Metab , vol.8 , pp. 38-48
    • Li, Y.1    Xu, W.2    McBurney, M.W.3    Longo, V.D.4
  • 53
    • 34447299716 scopus 로고    scopus 로고
    • The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN
    • Papakonstanti E a, Ridley AJ, Vanhaesebroeck B, (2007) The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. EMBO J 26: 3050-3061.
    • (2007) EMBO J , vol.26 , pp. 3050-3061
    • Papakonstanti, E.1    Ridley, A.J.2    Vanhaesebroeck, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.