Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae

Molecular Biology of the Cell

Volumn 10, Issue 10, 1999, Pages 3125-3136

  Kim, Sangkyu ^a   Benguria, Alberto ^a   Lai, Chi Yung ^a   Jazwinski, S Michal ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; HISTONE DEACETYLASE; RIBOSOME DNA;

ARTICLE; CELL AGING; FUNGAL GENETICS; GENE EXPRESSION; GENE LOCUS; LIFESPAN; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0032831936     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.10.10.3125     Document Type: Article

References (63)

1. Allsopp, R., Vaziri, H., Patterson, C., Goldstein, S., Younglai, E.V., Futcher, A.B., Greider, C.W., and Harley, C.B. (1992). Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10114-10118.
2. Aparicio, O.M., Billington, B.L., and Gottschling, D.E. (1991). Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66, 1279-1287.
3. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K. (1993). Current Protocols in Molecular Biology, New York: John Wiley & Sons.
4. Bodnar, A.G., Ouellette, M., Frolkis, M., Holt, S.E., Chiu, C.-P., Morin, G.B., Harley, C.B., Shay, J.W., Lichtsteiner, S., and Wright, W.E. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
5. Bryk, M., Banerjee, M., Murphy, M., Knudsen, K.E., Garfinkel, D.J., and M.J. Curcio. (1997). Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11, 225-269.
6. Chen, J.B., Sun, J., and Jazwinski, S.M. (1990). Prolongation of the yeast life span by the v-Ha-RAS oncogene. Mol. Microbiol. 4, 2081-2086.
7. Conrad-Webb, H., and Butow, R.A. (1995). A polymerase switch in the synthesis of rRNA in Saccharomyces cerevisiae. Mol. Cell. Biol. 15, 2420-2428.
8. Cost, G.J., and Boeke, J.D. (1996). A useful colony color phenotype associated with the yeast selectable/counterselectable marker MET15. Yeast 12, 939-941.
9. D'mello, N.P., and Jazwinski, S.M. (1991). Telomere length constancy during aging of Saccharomyces cerevisiae. J. Bacteriol. 173, 6709-6713.
10. Egilmez, N.K., Chen, J.B., and Jazwinski, S.M. (1989). Specific alterations in transcript prevalence during the yeast life span. J. Biol. Chem. 264, 14312-14317.
11. Egilmez, N.K., Chen, J.B., and Jazwinski, S.M. (1990). Preparation and partial characterization of old yeast cells. J. Gerontol. 45, B9-B17.
12. Egilmez, N.K., and Jazwinski, S.M. (1989). Evidence for the involvement of a cytoplasmic factor in the aging of the yeast Saccharomyces cerevisiae. J. Bacteriol. 171, 37-42.
13. Feng, J., et al. (1995). The RNA component of human telomerase. Science 269, 1236-1241.
14. Fritze, C.E., Verschueren, K., Strich, R., and Easton Esposito, R. (1997). Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA. EMBO J. 16, 6495-6509.
15. Gottlieb, S., and Esposito, R.E. (1989). A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 56, 771-776.
16. Gottschling, D.E., Aparicio, O.M., Billington, B.L., and Zakian, V.A. (1990). Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63, 751-762.
17. Grunstein, M. (1997). Histone acetylation in chromatin structure and transcription. Nature 389, 349-352.
18. Harley, C.B. (1991). Telomere loss: mitotic clock or genetic time bomb? Mutat. Res. 256, 271-282.
19. Harley, C.B., Futcher, A.B., and Greider, G.W. (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460.
20. Hecht, A., Laroche, T., Strahl-Bolsinger, S., Gasser, S.M., and Grunstein, M. (1995). Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80, 583-592.
21. Hecht, A., Strahl-Bolsinger, S., and Grunstein, M. (1996). Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383, 92-96.
22. Henikoff, S. (1990). Position effect variegation after 60 years. Trends Genet. 6, 422-426.
23. Herskowitz, I., and Jensen, R.E. (1991). Putting the HO gene to work: practical uses for mating-type switching. Methods Enzymol. 194, 132-146.
24. Jazwinski, S.M. (1996). Longevity-assurance genes and mitochondrial DNA alterations: yeast and filamentous fungi. In: Handbook of the Biology of Aging, 4th ed., ed. E.L. Schneider and J.W. Rowe, San Diego: Academic Press, 39-54.
25. Jazwinski, S.M., Kim S., Lai, C.-Y., and Benguria, A. (1998). Epigenetic stratification: the role of individual change in the biological aging process. Exp. Gerontol. 33, 571-580.
26. Jiang, Y.W., and Stillman, D.J. (1996). Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus. Genes Dev. 10, 604-619.
27. Johnson, L.M., Fisher-Adams, G., and Grunstein, M. (1992). Identification of a nonbasic domain in the histone H4 N-terminus required for repression of the yeast silent mating loci. EMBO J. 11, 2201-2209.
28. Johnson, L.M., Kayne, P.S., Kahn, E.S., and Grunstein, M. (1990). Genetic evidence for an interaction between SIR3 and histone H4 in the repression of the silent mating loci in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 87:6286-6290.
29. Kennedy, B.K., Austriaco, N.R., Jr., Zhang, J., and Guarente, L. (1995). Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80: 485-496.
30. Kennedy, B.K., Gotta, M., Sinclair, D.A., Mills, K., McNabb, D.S., Murthy, M., Pak, S.M., Laroche, T., Gasser, S.M., and Guarente, L. (1997). Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell 89, 381-391.
31. Kim, S., Kirchman, P.A., Benguria, A., and Jazwinski, S.M. (1998). Experimentation with the yeast model. In: Methods in Aging Research, ed. B.P. Yu, Boca Raton: CRC Press, 191-213.
32. Kim, S., Villeponteau, B., and Jazwinski, S.M. (1996). Effect of replicative age on transcriptional silencing near telomeres in Saccharomyces cerevisiae. Biochem. Biophy. Res. Comm. 219, 370-376.
33. Kirchman, P.A., Kim, S., Lai, C.-Y., and Jazwinski, S.M. (1999). Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. Genetics 252, 179-190.
34. Klar, A.J.S., Strathern, J.N., Broach, J.R., and Hicks, J.B. (1981). Regulation of transcription in expressed and unexpressed mating type cassettes of yeast. Nature 289, 239-244.
35. Laurenson, P., and Rine, J. (1992). Silencers, silencing, and heritable transcriptional states. Microbiol. Rev. 56, 543-560.
36. Loo, S., and Rine, J. (1995). Silencing and heritable domains of gene expression. Annu. Rev. Cell Dev. Biol. 22, 519-548.
37. Mortimer, R.K., and Johnston, J.R. (1959). Life span of individual yeast cells. Nature 183, 1751-1752.
38. Motizuki, M., and Tsurugi, K. (1992). The effect of aging on protein synthesis in the yeast Saccharomyces cerevisiae. Mech. Ageing Dev. 64, 235-245.
39. Muller, I. (1985). Parental age and the life span of zygotes of Saccharomyces cerevisiae. Antonie Leeuwenhoek J. Microbiol. Serol. 51, 1-10.
40. Muller, I., Zimmermann, M., Becker, D., and Flomer, M. (1980). Calendar life span versus budding life span of Saccharomyces cerevisiae. Mech. Ageing Dev. 12, 47-52.
41. Nasmyth, K.A., Tatchell, K., Hall, B.D., Astell, C.R., and Smith, M. (1981). A position effect in the control of transcription at yeast mating type loci. Nature 289, 244-250.
42. Park, E.C., and Szostak, J.W. (1990). Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML. Mol. Cell. Biol. 10, 4932-4934.
43. Renauld, H., Aparicio, O.M., Zierath, P., Billington, B.L., Chhablani, S.K., and Gottschling, D.E. (1993). Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev. 7, 1133-1145.
44. Rose, M.D., Winston, F., and Hieter, P. (1990). Methods in Yeast Genetics. A Laboratory Course Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
45. Rundlett, S.E., Carmen, A.A., Kobayashi, R., Bavykin, S., Turner, B.M., and Grunstein, M. (1996). HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. USA 93, 14503-14508.
46. Sikorski, R.S., and Hieter, P. (1989). A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122, 19-27.
47. Sinclair, D.A., and Guarente, L. (1997). Extrachromosomal rDNA circles: a cause of aging in yeast. Cell 91, 1033-1042.
48. Singer, M.S., and Gottschling, D.E. (1994). TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266, 404-409.
49. Smeal, T., Claus, J., Kennedy, B., Cole, F., and Guarente, L. (1996). Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae. Cell 84, 633-642.
50. Smith, J.S., and Boeke, J.D. (1997). An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11, 241-254.
51. Smith, J.S., Brachmann, C.B., Pillus, L., and Boeke, J.D. (1998). Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p. Genetics 149, 1205-1219.
52. Smith, J.S., Caputo, E., and Boeke, J.D. (1999). A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol. Cell. Biol. 19, 3184-3197.
53. Spofford, J.B. (1976). Position-effect variegation. In: The Genetics and Biology of Drosophila, Vol. 1C, ed. M. Ashburner and E. Novitski, New York: Academic Press, 955-1018.
54. Strahl-Bolsinger, S., Hecht, A., Luo, K., and Grunstein, M. (1997). SIR2 and S1R4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11, 83-93.
55. Struhl, K. (1998). Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12, 599-606.
56. Sun, J., Kale, S.P., Childress, A.M., Pinswasdi, C., and Jazwinski, S.M. (1994). Divergent roles of RAS1 and RAS2 in yeast longevity. J. Biol. Chem. 269, 18638-18645.
57. Sussel, L., Vannier, D., and Shore, D. (1995). Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure. Genetics 141, 873-888.
58. Taunton, J., Hassig, C.A., and Schreiber, S.L. (1996). A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272, 408-411.
59. Thompson, J.S., Ling, X., and Grunstein, M. (1994). The histone H3 amino terminus is required for both telomeric and silent mating locus repression in yeast. Nature 369, 245-247.
60. Vannier, D., Balderes, D., and Shore, D. (1996). Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae. Genetics 144, 1343-1353.
61. Vidal, M., and Gaber, R.F. (1991). RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol. 11, 6317-6327.
62. Wolffe, A.P. (1996). Histone deacetylase: a regulator of transcription. Science 272, 371-372.
63. Yang, W.M., Inouye, C., Zeng, Y., Bearss, D., and E. Seto. (1996). Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc. Natl. Acad. Sci. USA 93, 12845-12850.