The acetylation of tau inhibits its function and promotes pathological tau aggregation

Nature Communications

Volumn 2, Issue 1, 2011, Pages

  Cohen, Todd J ^a   Guo, Jing L ^a   Hurtado, David E ^a   Kwong, Linda K ^a   Mills, Ian P ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE; TAU PROTEIN; THIOFLAVINE; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; TAU 40 PROTEIN, HUMAN;

ACETYLATION; ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; MICROTUBULE; MOUSE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN FUNCTION; TAU ACETYLATION; TAUOPATHY; AGED; ANIMAL; BRAIN; CELL STRAIN HEK293; FEMALE; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; MICROTOMY; MIDDLE AGED; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING; TRANSGENIC MOUSE;

MUS MUSCULUS;

ACETYLATION; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; BRAIN; FEMALE; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LYSINE; MALE; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MICROTOMY; MICROTUBULES; MIDDLE AGED; NEURONS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 79953087890     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1255     Document Type: Article

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