Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis

Neuroscience Letters

Volumn 503, Issue 3, 2011, Pages 250-255

  Wang, Jing ^a   Zhang, Yun ^a   Tang, Lu ^a   Zhang, Nan ^a   Fan, Dongsheng ^a  

^a PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

Amyotrophic lateral sclerosis; Mitochondria biogenesis; Nicotinamide; Resveratrol; Sirtuin

Indexed keywords

ADENOSINE TRIPHOSPHATE; NICOTINAMIDE; RESVERATROL; SIRTUIN 1; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; ARTICLE; BIOGENESIS; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; DRUG EFFICACY; DRUG INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; MOTONEURON; NEUROPATHOLOGY; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; UPREGULATION;

AMYOTROPHIC LATERAL SCLEROSIS; ANNEXIN A5; BLOTTING, WESTERN; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MITOCHONDRIA; MOTOR NEURONS; MUTATION; NEUROPROTECTIVE AGENTS; NIACINAMIDE; PROPIDIUM; REAL-TIME POLYMERASE CHAIN REACTION; SIRTUIN 1; STILBENES; SUPEROXIDE DISMUTASE; TETRAZOLIUM SALTS; THIAZOLES; UP-REGULATION;

EID: 80053223811     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.08.047     Document Type: Article

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