Evidence for a common mechanism of SIRT1 regulation by allosteric activators

Science

Volumn 339, Issue 6124, 2013, Pages 1216-1219

  Hubbard, Basil P ^a   Gomes, Ana P ^a,b   Dai, Han ^c   Li, Jun ^a   Case, April W ^c   Considine, Thomas ^c   Riera, Thomas V ^c   Lee, Jessica E ^d   Yen E, Sook ^d   Lamming, Dudley W ^a,j   Pentelute, Bradley L ^e   Schuman, Eli R ^c   Stevens, Linda A ^f   Ling, Alvin J Y ^a   Armour, Sean M ^a   Michan, Shaday ^a,k   Zhao, Huizhen ^c   Jiang, Yong ^c   Sweitzer, Sharon M ^c   Blum, Charles A ^c   Disch, Jeremy S ^c   Ng, Pui Yee ^c   Howitz, Konrad T ^g,l   Rolo, Anabela P ^b,h   Hamuro, Yoshitomo ^d   Moss, Joel ^f   Perni, Robert B ^c   Ellis, James L ^c   Vlasuk, George P ^c   Sinclair, David A ^a,i   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c GLAXOSMITHKLINE   (United States)

^d ExSAR Corporation   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^g BIOMOL Research Laboratories Inc   (United States)

^h UNIVERSITY OF AVEIRO   (Portugal)

ⁱ UNIVERSITY OF NEW SOUTH WALES   (Australia)

^j WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^k INSTITUTO NACIONAL DE GERIATRÍA   (Mexico)

^l REACTION BIOLOGY CORPORATION   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR SCAFFOLD; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RESVERATROL; SIRTUIN 1; TRANSCRIPTION FACTOR FKHRL1;

DRUG; HYDROPHOBICITY; MOLECULAR ANALYSIS; SUBSTRATE;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DENATURATION; ENZYME LOCALIZATION; ENZYME REGULATION; ISOTHERMAL TITRATION CALORIMETRY; MICHAELIS CONSTANT; PRIORITY JOURNAL; WILD TYPE;

EID: 84874721105     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1231097     Document Type: Article

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