Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery

Advanced Drug Delivery Reviews

Volumn 65, Issue 11-12, 2013, Pages 1626-1663

  Vladisavljević, Goran T ^a   Khalid, Nauman ^b,c   Neves, Marcos A ^b,d   Kuroiwa, Takashi ^b,e   Nakajima, Mitsutoshi ^b,d   Uemura, Kunihiko ^b   Ichikawa, Sosaku ^d   Kobayashi, Isao ^b  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

^e TOKYO CITY UNIVERSITY   (Japan)

Author keywords

Biological processing; Device fabrication; Functional materials; Microfluidics; Monodisperse droplets; Parallel flow; Scale up; Unit operation

Indexed keywords

BIOLOGICAL PROCESSING; DEVICE FABRICATIONS; HIGH-THROUGHPUT ANALYSIS; INTERDISCIPLINARY TECHNOLOGIES; MICRO FLUIDIC APPLICATIONS; MONODISPERSE DROPLETS; NOVEL FUNCTIONAL MATERIALS; SCALE-UP;

BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; CHEMICAL CONTAMINATION; DROPS; DRUG DELIVERY; EMULSIONS; FUNCTIONAL MATERIALS; MOLECULES; PARALLEL FLOW; SYNTHESIS (CHEMICAL); UNIT OPERATIONS (OIL WELLS);

MICROFLUIDICS;

DIMETICONE; MACROGOL; NANOPARTICLE; POLY(METHYL METHACRYLATE); POLYGLACTIN; SILICON;

ACCURACY; ADSORPTION; BIOCOMPATIBILITY; CRYSTALLIZATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG MIXTURE; EMULSION; FLOW RATE; GELATION; HYDRODYNAMICS; HYDROPHILICITY; HYDROPHOBICITY; LAB ON A CHIP; MATERIAL STATE; METABOLOMICS; MICROFLUIDICS; NUCLEIC ACID ANALYSIS; PARTICLE SIZE; PRIORITY JOURNAL; PROTEOMICS; REVIEW; SINGLE CELL ANALYSIS; SURFACE PROPERTY; TOXICITY TESTING; VISCOSITY; ZETA POTENTIAL;

BIOLOGICAL PROCESSING; DEVICE FABRICATION; FUNCTIONAL MATERIALS; MICROFLUIDICS; MONODISPERSE DROPLETS; PARALLEL FLOW; SCALE-UP; UNIT OPERATION;

ANIMALS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG DISCOVERY; EMULSIONS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LAB-ON-A-CHIP DEVICES; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; NANOPARTICLES;

EID: 84887608703     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2013.07.017     Document Type: Review

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