Spherical and cylindrical microencapsulation of living cells using microfluidic devices

Korea Australia Rheology Journal

Volumn 19, Issue 3, 2007, Pages 157-164

  Hong, Joung Sook ^a   Shin, Su Jung ^a   Lee, SangHoon ^a   Wong, Edeline ^b   Cooper White, Justin ^b  

^a Korea University   (South Korea)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Bead; Calcium alginate gel; Fibre; Microencapsulation; Microfluidics

Indexed keywords

EID: 43449117216     PISSN: 1226119X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Anna, S.L., N. Bontoux and H.A. Stone, 2003, Formation of dispersions using "flow focusing" in microchannels, App. Phy. Lett. 82(3), 364-366.
2. Chang, T.M.S., 1964, Semipermeable microcapsule, Science 146, 524-525.
3. Fan, M.Y., Z.P. Lum, X.W Fu, L. Levesque, I.T. Tai and A.M. Sun, 1990, Reversal of diabetes in BB rats by transplantation of encapsulated pancreatic islets, Diabetes 39, 519-522.
4. Hong, J.S. and Cooper-White, J.J., 2007, Drop formation of anon-Newtonian fluid in a flow-focusing microfluidic channel, in preparation.
5. Jeong, W.J., J.Y. Kim, S.J. Kim, S.H. Lee, G. Mensing, and D.J. Beebe, 2004, Lab Chip 4, 576-580.
6. Jeong, W.J., J.Y. Kim, J. Choo, E.K. Lee, C.S. Han, D.J. Beebe, G.H. Seong and S.H. Lee, 2005, Langmuir 21, 3738-3741.
7. Khattak, S.F., S.R. Bhatia and S.C Roberts, 2005, Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents, Tissue Engineering 11(5/6), 974-983.
8. Lacy, P.E. and M. Kostianovsky, 1967, Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16, 35-39.
9. Li, C.H., 2006, Microfluidic Lab-on a-chip for chemical and biological analysis and discovery, CRC press.
10. Lim, F. and A.M. Sun, 1980, Microencapsulated islets as bioartificial endocrine pancreas, Science 210, 908-910.
11. Microprobes, Product information MP07013, LIVE/DEAD Reduced Biohazard Viability/Cytotoxicity Kit#1 (L-7013).
12. Microprobes, Product information MP03224, LIVE/DEAD Viability/ Cytotoxicity Kit for mammalian cells.
13. Rayleigh, L., 1879, On the capillary phenomena of jets, Proc. R. Soc. 29, 71-97.
14. Strand, B.L., 2001, Poly-L-lysine induces fibrosis on alginate microcapsules via the induction of cytokines, Cell Transplant. 10, 263-275.
15. Sun, Y.L., X.J. Ma, D.B. Zhou, I. Vacek and A.M. Sun, 1996, Normalization of diabetes in spontaneously diabetic cynomologous monkeys by xenografts of microencapsulated porcine islets without immunosuppression, J. Clin. Invest. 98, 1417-1422.
16. Sugiura, S., T. Oda, Y. Izumida, Y. Aoyagi, M. Satake, A. Ochiai, N. Ohkohchi and M. Nakajima, 2005, Size control of calcium alginate beads containing living cells using micro-nozzle array, Biomaterials 26, 3327-3331,
17. Utada, A.S., E. Lorenceau, D.R. Link, P.D. Kaplan, H.A. Stone and DA. Weitz, 2005, Monodisperse double emulsions generated from a microcapillary device, Science 308, 537-541,
18. Xu, Q., M. Nakajima, 2004, The generation of highly monodisperse droplets through the breakup of hydrodynamically focused microthread in a microfluidic device, App. Phy. Lett. 85(17), 3726-3728.