PLGA-mPEG nanoparticles of cisplatin: In vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties

Journal of Controlled Release

Volumn 79, Issue 1-3, 2002, Pages 123-135

  Avgoustakis, K ^a   Beletsi, A ^a   Panagi, Z ^a   Klepetsanis, P ^a   Karydas, A G ^b   Ithakissios, D S ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b INSTITUTE OF NUCLEAR PHYSICS   (Greece)

Author keywords

Blood profile; Cisplatin; Degradation; Drug release; Poly(lactide co glycolide) polyethyleneglycol nanoparticles

Indexed keywords

CISPLATIN; MACROGOL; NANOPARTICLE; PHOSPHATE; POLYGLACTIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG RELEASE; DRUG TARGETING; EMULSION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; SYSTEMIC CIRCULATION; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOCOMPATIBLE MATERIALS; CISPLATIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG EVALUATION, PRECLINICAL; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, SCANNING; NANOTECHNOLOGY; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910;

EID: 0037133087     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00530-2     Document Type: Article

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