Inhibition of Hedgehog signaling in the gastrointestinal tract: Targeting the cancer microenvironment

Cancer Treatment Reviews

Volumn 40, Issue 1, 2014, Pages 12-21

  Merchant, Juanita L ^a   Saqui Salces, Milena ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Gli1; MDSCs; Primary cilia; Stomach; Stroma

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ALPHA TUBULIN; ANGIOPOIETIN 1; BMI1 PROTEIN; CANCER GROWTH FACTOR; CASEIN KINASE I; CYCLIC AMP DEPENDENT PROTEIN KINASE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN PATCHED; PROTEIN PATCHED 1; PROTEIN PATCHED 2; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; VASCULOTROPIN; VIMENTIN;

BASAL CELL NEVUS SYNDROME; BILE DUCT CANCER; BILE DUCT CARCINOMA; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL PROLIFERATION; CHRONIC GASTRITIS; COLON CANCER; DIGESTIVE SYSTEM CANCER; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; ESOPHAGUS CANCER; GASTROINTESTINAL CARCINOMA; GASTROINTESTINAL DYSPLASIA; GENE TARGETING; HEDGEHOG SIGNALING PATHWAY; HELICOBACTER; HELICOBACTER INFECTION; HUMAN; INTESTINE CANCER; INTESTINE METAPLASIA; LIVER CANCER; LIVER CELL CARCINOMA; MALIGNANT TRANSFORMATION; MAMMAL CELL; MESENCHYME; NONHUMAN; ONCOGENE; ONCOGENE C MYB; PANCREAS CANCER; PARACRINE SIGNALING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; STOMACH CANCER; STROMA CELL; T LYMPHOCYTE; TUMOR MICROENVIRONMENT;

EID: 84887034107     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2013.08.003     Document Type: Review

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