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Volumn 142, Issue 5, 2012, Pages

Gastric sonic hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori

Author keywords

Bacteria; Gastric Cancer; Monocyte; Signaling

Indexed keywords

CD11B ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 1BETA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN;

EID: 84862824410     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.01.029     Document Type: Article
Times cited : (89)

References (51)
  • 1
    • 0033959945 scopus 로고    scopus 로고
    • A predominant Th1 type of immune response is induced early during acute Helicobacter pylori infection in rhesus macaques
    • J.J. Mattapallil, S. Dandekar, D.R. Canfield A predominant Th1 type of immune response is induced early during acute Helicobacter pylori infection in rhesus macaques Gastroenterology 118 2000 307 315
    • (2000) Gastroenterology , vol.118 , pp. 307-315
    • Mattapallil, J.J.1    Dandekar, S.2    Canfield, D.R.3
  • 2
    • 0035877051 scopus 로고    scopus 로고
    • The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice
    • K.A. Eaton, M. Mefford, T. Thevenot The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice J Immunol 166 2001 7456 7461
    • (2001) J Immunol , vol.166 , pp. 7456-7461
    • Eaton, K.A.1    Mefford, M.2    Thevenot, T.3
  • 3
    • 16444361865 scopus 로고    scopus 로고
    • Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma
    • Y. Zavros, K.A. Eaton, W. Kang Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma Oncogene 24 2005 2354 2366
    • (2005) Oncogene , vol.24 , pp. 2354-2366
    • Zavros, Y.1    Eaton, K.A.2    Kang, W.3
  • 4
    • 0242363135 scopus 로고    scopus 로고
    • Treatment of Helicobacter gastritis with IL-4 requires somatostatin
    • Y. Zavros, S. Rathinavelu, J.Y. Kao Treatment of Helicobacter gastritis with IL-4 requires somatostatin Proc Natl Acad Sci U S A 100 2003 12944 12949
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12944-12949
    • Zavros, Y.1    Rathinavelu, S.2    Kao, J.Y.3
  • 5
    • 35948942752 scopus 로고    scopus 로고
    • Host response to Helicobacter pylori infection before initiation of the adaptive immune response
    • H.M. Algood, J. Gallo-Romero, K.T. Wilson Host response to Helicobacter pylori infection before initiation of the adaptive immune response FEMS Immunol Med Microbiol 51 2007 577 586
    • (2007) FEMS Immunol Med Microbiol , vol.51 , pp. 577-586
    • Algood, H.M.1    Gallo-Romero, J.2    Wilson, K.T.3
  • 6
    • 39149133212 scopus 로고    scopus 로고
    • NF-kappaB activation during acute Helicobacter pylori infection in mice
    • R.L. Ferrero, P. Avé, D. Ndiaye NF-kappaB activation during acute Helicobacter pylori infection in mice Infect Immun 76 2008 551 561
    • (2008) Infect Immun , vol.76 , pp. 551-561
    • Ferrero, R.L.1    Avé, P.2    Ndiaye, D.3
  • 7
    • 33947312885 scopus 로고    scopus 로고
    • The inflammatory and immune response to Helicobacter pylori infection
    • K.A.R. Robinson, J.C. Atherton The inflammatory and immune response to Helicobacter pylori infection Best Pract Res Clin Gastroenterol 21 2007 237 259
    • (2007) Best Pract Res Clin Gastroenterol , vol.21 , pp. 237-259
    • Robinson, K.A.R.1    Atherton, J.C.2
  • 8
    • 0037289832 scopus 로고    scopus 로고
    • Role of NF-kappaB and AP-1 on Helicobater pylori-induced IL-8 expression in AGS cells
    • S.H. Chu, H. Kim, J.Y. Seo Role of NF-kappaB and AP-1 on Helicobater pylori-induced IL-8 expression in AGS cells Dig Dis Sci 48 2003 257 265
    • (2003) Dig Dis Sci , vol.48 , pp. 257-265
    • Chu, S.H.1    Kim, H.2    Seo, J.Y.3
  • 9
    • 34447092208 scopus 로고    scopus 로고
    • Immunology of Helicobacter pylori: Insights into the failure of the immune response and perspectives on vaccine studies
    • K.T. Wilson, J.E. Crabtree Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies Gastroenterology 133 2007 288 308
    • (2007) Gastroenterology , vol.133 , pp. 288-308
    • Wilson, K.T.1    Crabtree, J.E.2
  • 10
    • 77954853797 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 is generated via TGF-beta by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection
    • H. Mutoh, M. Sashikawa, H. Hayakawa Monocyte chemoattractant protein-1 is generated via TGF-beta by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection Cancer Sci 101 2010 1783 1789
    • (2010) Cancer Sci , vol.101 , pp. 1783-1789
    • Mutoh, H.1    Sashikawa, M.2    Hayakawa, H.3
  • 11
    • 0031056837 scopus 로고    scopus 로고
    • Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta
    • T. Watanabe, T. Arakawa, T. Fukuda Role of neutrophils in a rat model of gastric ulcer recurrence caused by interleukin-1 beta Am J Pathol 150 1997 971 979
    • (1997) Am J Pathol , vol.150 , pp. 971-979
    • Watanabe, T.1    Arakawa, T.2    Fukuda, T.3
  • 12
    • 77953747962 scopus 로고    scopus 로고
    • Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages
    • M. Asim, R. Chaturvedi, S. Hoge Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages J Biol Chem 285 2010 20343 20357
    • (2010) J Biol Chem , vol.285 , pp. 20343-20357
    • Asim, M.1    Chaturvedi, R.2    Hoge, S.3
  • 13
    • 42949138869 scopus 로고    scopus 로고
    • Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice
    • M. Kaparakis, A.K. Walduck, J.D. Price Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice Infect Immun 76 2008 2235 2239
    • (2008) Infect Immun , vol.76 , pp. 2235-2239
    • Kaparakis, M.1    Walduck, A.K.2    Price, J.D.3
  • 14
    • 75149149098 scopus 로고    scopus 로고
    • Loss of parietal cell expression of Sonic Hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells
    • C. Xiao, S.A. Ogle, M.A. Schumacher Loss of parietal cell expression of Sonic Hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells Gastroenterology 138 2010 550 561
    • (2010) Gastroenterology , vol.138 , pp. 550-561
    • Xiao, C.1    Ogle, S.A.2    Schumacher, M.A.3
  • 15
    • 0036839405 scopus 로고    scopus 로고
    • Sonic Hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract
    • G.R. van den Brink, J.C. Hardwick, C. Nielsen Sonic Hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract Gut 51 2002 628 633
    • (2002) Gut , vol.51 , pp. 628-633
    • Van Den Brink, G.R.1    Hardwick, J.C.2    Nielsen, C.3
  • 16
    • 51149106366 scopus 로고    scopus 로고
    • Sonic Hedgehog is associated with H+,K+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation
    • Y. Zavros, M.A. Orr, C. Xiao Sonic Hedgehog is associated with H+,K+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation Am J Physiol 295 2008 G99 G111
    • (2008) Am J Physiol , vol.295
    • Zavros, Y.1    Orr, M.A.2    Xiao, C.3
  • 17
    • 38149120774 scopus 로고    scopus 로고
    • Commercially available recombinant Sonic Hedgehog up-regulates Ptc and modulates the cytokine and chemokine expression of human macrophages: An effect mediated by endotoxin contamination?
    • S.J. Wakelin, J.L. Forsythe, O.J. Garden Commercially available recombinant Sonic Hedgehog up-regulates Ptc and modulates the cytokine and chemokine expression of human macrophages: an effect mediated by endotoxin contamination? Immunobiology 213 2008 25 38
    • (2008) Immunobiology , vol.213 , pp. 25-38
    • Wakelin, S.J.1    Forsythe, J.L.2    Garden, O.J.3
  • 18
    • 0037103336 scopus 로고    scopus 로고
    • Sonic Hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes
    • J.A. Lowrey, G.A. Stewart, S. Lindey Sonic Hedgehog promotes cell cycle progression in activated peripheral CD4(+) T lymphocytes J Immunol 169 2002 1869 1875
    • (2002) J Immunol , vol.169 , pp. 1869-1875
    • Lowrey, J.A.1    Stewart, G.A.2    Lindey, S.3
  • 19
    • 0037111420 scopus 로고    scopus 로고
    • Sonic Hedgehog signaling modulates activation of and cytokine production by human peripheral CD4+ T cells
    • G.A. Stewart, J.A. Lowrey, S.J. Wakelin Sonic Hedgehog signaling modulates activation of and cytokine production by human peripheral CD4+ T cells J Immunol 169 2002 5451 5457
    • (2002) J Immunol , vol.169 , pp. 5451-5457
    • Stewart, G.A.1    Lowrey, J.A.2    Wakelin, S.J.3
  • 20
    • 68949194359 scopus 로고    scopus 로고
    • Repair-related activation of Hedgehog signaling promotes cholangiocyte chemokine production
    • A. Omenetti, W.K. Syn, Y. Jung Repair-related activation of Hedgehog signaling promotes cholangiocyte chemokine production Hepatology 50 2009 518 527
    • (2009) Hepatology , vol.50 , pp. 518-527
    • Omenetti, A.1    Syn, W.K.2    Jung, Y.3
  • 21
    • 75149191890 scopus 로고    scopus 로고
    • Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog
    • M. Waghray, Y. Zavros, M. Saqui-Salces Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog Gastrotenterology 138 2010 562 572
    • (2010) Gastrotenterology , vol.138 , pp. 562-572
    • Waghray, M.1    Zavros, Y.2    Saqui-Salces, M.3
  • 22
    • 10044287361 scopus 로고    scopus 로고
    • Hh pathway expression in human gut tissues and in inflammatory gut diseases
    • C.M. Nielsen, J. Williams, G.R. van den Brink Hh pathway expression in human gut tissues and in inflammatory gut diseases Lab Invest 84 2004 1631 1642
    • (2004) Lab Invest , vol.84 , pp. 1631-1642
    • Nielsen, C.M.1    Williams, J.2    Van Den Brink, G.R.3
  • 23
    • 0037385280 scopus 로고    scopus 로고
    • Expression of the developmental Sonic Hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes
    • G.A. Stewart, G.F. Hoyne, S.A. Ahmad Expression of the developmental Sonic Hedgehog (Shh) signalling pathway is up-regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes J Pathol 199 2003 488 495
    • (2003) J Pathol , vol.199 , pp. 488-495
    • Stewart, G.A.1    Hoyne, G.F.2    Ahmad, S.A.3
  • 24
    • 72449209673 scopus 로고    scopus 로고
    • Sonic Hedgehog is a potent chemoattractant for human monocytes: Diabetes mellitus inhibits Sonic Hedgehog-induced monocyte chemotaxis
    • M. Dunaeva, S. Voo, C. van Oosterhoud Sonic Hedgehog is a potent chemoattractant for human monocytes: diabetes mellitus inhibits Sonic Hedgehog-induced monocyte chemotaxis Basic Res Cardiol 105 2010 61 71
    • (2010) Basic Res Cardiol , vol.105 , pp. 61-71
    • Dunaeva, M.1    Voo, S.2    Van Oosterhoud, C.3
  • 25
    • 0031948701 scopus 로고    scopus 로고
    • Impaired gastric acid secretion in gastrin-deficient mice
    • L. Friis-Hansen, F. Sundler, Y. Li Impaired gastric acid secretion in gastrin-deficient mice Am J Physiol 274 1998 G561 G568
    • (1998) Am J Physiol , vol.274
    • Friis-Hansen, L.1    Sundler, F.2    Li, Y.3
  • 26
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • B.E. Clausen, C. Burkhardt, W. Reith Conditional gene targeting in macrophages and granulocytes using LysMcre mice Transgenic Res 8 1999 265 277
    • (1999) Transgenic Res , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3
  • 27
    • 0035691559 scopus 로고    scopus 로고
    • Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
    • F. Long, X.M. Zhang, S. Karp Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation Development 128 2001 5099 5108
    • (2001) Development , vol.128 , pp. 5099-5108
    • Long, F.1    Zhang, X.M.2    Karp, S.3
  • 28
    • 0030941212 scopus 로고    scopus 로고
    • A standardized mouse model of Helicobacter pylori infection: Introducing the Sydney strain
    • A. Lee, J. O'Rourke, M.C. De Ungria A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain Gastroenterology 112 1997 1386 1397
    • (1997) Gastroenterology , vol.112 , pp. 1386-1397
    • Lee, A.1    O'Rourke, J.2    De Ungria, M.C.3
  • 29
    • 0036142330 scopus 로고    scopus 로고
    • Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice
    • Y. Zavros, G. Rieder, A. Ferguson Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice Gastroenterology 122 2002 119 133
    • (2002) Gastroenterology , vol.122 , pp. 119-133
    • Zavros, Y.1    Rieder, G.2    Ferguson, A.3
  • 30
    • 77955621885 scopus 로고    scopus 로고
    • Role of innate immunity in Helicobacter pylori-induced gastric malignancy
    • R.M. Peek, C. Fiske, K.T. Wilson Role of innate immunity in Helicobacter pylori-induced gastric malignancy Physiol Rev 90 2010 831 858
    • (2010) Physiol Rev , vol.90 , pp. 831-858
    • Peek, R.M.1    Fiske, C.2    Wilson, K.T.3
  • 31
    • 38149027631 scopus 로고    scopus 로고
    • Cyclopamine inhibition of the Sonic Hedgehog pathway in the stomach requires concomitant acid inhibition
    • M. El-Zaatari, A.M. Grabowska, A.J. McKenzie Cyclopamine inhibition of the Sonic Hedgehog pathway in the stomach requires concomitant acid inhibition Regul Pept 146 2008 131 139
    • (2008) Regul Pept , vol.146 , pp. 131-139
    • El-Zaatari, M.1    Grabowska, A.M.2    McKenzie, A.J.3
  • 32
    • 36349013850 scopus 로고    scopus 로고
    • Reduced pepsin A processing of Sonic Hedgehog in parietal cells precedes gastric atrophy and transformation
    • Y. Zavros, M. Waghray, A. Tessier Reduced pepsin A processing of Sonic Hedgehog in parietal cells precedes gastric atrophy and transformation J Biol Chem 282 2007 33265 33274
    • (2007) J Biol Chem , vol.282 , pp. 33265-33274
    • Zavros, Y.1    Waghray, M.2    Tessier, A.3
  • 33
    • 0027518383 scopus 로고
    • Gastric interleukin-8 and IgA IL-8 autoantibodies in Helicobacter pylori infection
    • J.E. Crabtree, P. Peichl, J.I. Wyatt Gastric interleukin-8 and IgA IL-8 autoantibodies in Helicobacter pylori infection Scand J Gastroenterol 37 1993 65 70
    • (1993) Scand J Gastroenterol , vol.37 , pp. 65-70
    • Crabtree, J.E.1    Peichl, P.2    Wyatt, J.I.3
  • 34
    • 79959790271 scopus 로고    scopus 로고
    • Novel regulators of the systemic response to lipopolysaccharide
    • I.V. Yang, S. Alper, B. Lackford Novel regulators of the systemic response to lipopolysaccharide Am J Respir Cell Mol Biol 45 2011 393 402
    • (2011) Am J Respir Cell Mol Biol , vol.45 , pp. 393-402
    • Yang, I.V.1    Alper, S.2    Lackford, B.3
  • 35
    • 79961221518 scopus 로고    scopus 로고
    • Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium
    • A. Callejo, A. Bilioni, E. Mollica Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium Proc Natl Acad Sci U S A 108 2011 12591 12598
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12591-12598
    • Callejo, A.1    Bilioni, A.2    Mollica, E.3
  • 36
    • 0035822098 scopus 로고    scopus 로고
    • A freely diffusible form of Sonic Hedgehog mediates long-range signalling
    • X. Zeng, J.A. Goetz, L.M. Suber A freely diffusible form of Sonic Hedgehog mediates long-range signalling Nature 411 2001 716 720
    • (2001) Nature , vol.411 , pp. 716-720
    • Zeng, X.1    Goetz, J.A.2    Suber, L.M.3
  • 37
    • 33748556776 scopus 로고    scopus 로고
    • Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens
    • M.C. Martnez, F. Larbret, F. Zobairi Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens Blood 108 2006 3012 3020
    • (2006) Blood , vol.108 , pp. 3012-3020
    • Martnez, M.C.1    Larbret, F.2    Zobairi, F.3
  • 38
    • 58249124375 scopus 로고    scopus 로고
    • Characterization of Sonic Hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo
    • H. Kasperczyk, B. Baumann, K.M. Debatin Characterization of Sonic Hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo FASEB J 23 2009 21 33
    • (2009) FASEB J , vol.23 , pp. 21-33
    • Kasperczyk, H.1    Baumann, B.2    Debatin, K.M.3
  • 39
    • 34250336769 scopus 로고    scopus 로고
    • De-regulation of the Sonic Hedgehog pathway in the InsGas mouse model of gastric carcinogenesis
    • M. El-Zaatari, A. Tobias, A.M. Grabowska De-regulation of the Sonic Hedgehog pathway in the InsGas mouse model of gastric carcinogenesis Br J Cancer 96 2007 1855 1861
    • (2007) Br J Cancer , vol.96 , pp. 1855-1861
    • El-Zaatari, M.1    Tobias, A.2    Grabowska, A.M.3
  • 40
    • 0036259861 scopus 로고    scopus 로고
    • Role of gamma interferon in Helicobacter pylori induction of inflammatory mediators during murine infection
    • M. Obonyo, D.G. Guiney, J. Harwood Role of gamma interferon in Helicobacter pylori induction of inflammatory mediators during murine infection Infect Immun 70 2002 3295 3299
    • (2002) Infect Immun , vol.70 , pp. 3295-3299
    • Obonyo, M.1    Guiney, D.G.2    Harwood, J.3
  • 41
    • 0021259505 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • B.J. Marshall, J.R. Warren Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration Lancet 1 1984 1311 1315
    • (1984) Lancet , vol.1 , pp. 1311-1315
    • Marshall, B.J.1    Warren, J.R.2
  • 42
    • 0025885785 scopus 로고
    • Mucosal tumour necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis
    • J.E. Crabtree, T.M. Shallcross, R.V. Heatley Mucosal tumour necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis Gut 62 1991 1473 1477
    • (1991) Gut , vol.62 , pp. 1473-1477
    • Crabtree, J.E.1    Shallcross, T.M.2    Heatley, R.V.3
  • 43
    • 75149149098 scopus 로고    scopus 로고
    • Loss of parietal cell expression of Sonic Hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells
    • C. Xiao, S.A. Ogle, M.A. Schumacher Loss of parietal cell expression of Sonic Hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells Gastroenterology 138 2010 550 561
    • (2010) Gastroenterology , vol.138 , pp. 550-561
    • Xiao, C.1    Ogle, S.A.2    Schumacher, M.A.3
  • 44
    • 0031948701 scopus 로고    scopus 로고
    • Impaired gastric acid secretion in gastrin-deficient mice
    • L. Friis-Hansen, F. Sundler, Y. Li Impaired gastric acid secretion in gastrin-deficient mice Am J Physiol 274 1998 G561 G568
    • (1998) Am J Physiol , vol.274
    • Friis-Hansen, L.1    Sundler, F.2    Li, Y.3
  • 45
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • B.E. Clausen, C. Burkhardt, W. Reith Conditional gene targeting in macrophages and granulocytes using LysMcre mice Transgenic Res 8 1999 265 277
    • (1999) Transgenic Res , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3
  • 46
    • 0035691559 scopus 로고    scopus 로고
    • Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
    • F. Long, X.M. Zhang, S. Karp Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation Development 128 2001 5099 5108
    • (2001) Development , vol.128 , pp. 5099-5108
    • Long, F.1    Zhang, X.M.2    Karp, S.3
  • 47
    • 0030941212 scopus 로고    scopus 로고
    • A standardized mouse model of Helicobacter pylori infection: Introducing the Sydney Strain
    • A. Lee, J. O'Rourke, M.C. De Ungria A standardized mouse model of Helicobacter pylori infection: introducing the Sydney Strain Gastroenterology 112 1997 1386 1397
    • (1997) Gastroenterology , vol.112 , pp. 1386-1397
    • Lee, A.1    O'Rourke, J.2    De Ungria, M.C.3
  • 48
    • 0035500298 scopus 로고    scopus 로고
    • IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis
    • J. Lehmann, S. Bellmann, C. Werner IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis J Immunol 167 2001 5304 5315
    • (2001) J Immunol , vol.167 , pp. 5304-5315
    • Lehmann, J.1    Bellmann, S.2    Werner, C.3
  • 49
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • K. Livak, T. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.1    Schmittgen, T.2
  • 50
    • 0036142330 scopus 로고    scopus 로고
    • Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice
    • Y. Zavros, G. Rieder, A. Ferguson Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice Gastroenterology 122 2002 119 133
    • (2002) Gastroenterology , vol.122 , pp. 119-133
    • Zavros, Y.1    Rieder, G.2    Ferguson, A.3
  • 51
    • 0025875478 scopus 로고
    • The secretory kinetics of the G cell in omeprazole-treated rats
    • H.C. Dockray GJ, D. Evans, A. Varro The secretory kinetics of the G cell in omeprazole-treated rats Gastroenterology 100 1991 1187 1194
    • (1991) Gastroenterology , vol.100 , pp. 1187-1194
    • Dockray Gj, H.C.1    Evans, D.2    Varro, A.3


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