Paracrine sonic hedgehog signaling derived from tumor epithelial cells: A key regulator in the pancreatic tumor microenvironment

Critical Reviews in Eukaryotic Gene Expression

Volumn 22, Issue 2, 2012, Pages 97-108

  Li, Xuqi ^a   Ma, Qingyong ^a   Duan, Wanxing ^a   Liu, Han ^a   Xu, Hongqin ^a   Wu, Eexi ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Pancreatic cancer; Sonic hedgehog; Stroma; Tumor microenvironment

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; CUR 199691; CYCLOPAMINE; GEMCITABINE; LPE 225; N (3 METHOXYBENZYL) 3,3 DIMETHYL N [1 (3,4 METHYLENEDIOXYBENZYL) 2 (1 PIPERAZINYLCARBONYL) 4 PYRROLIDINYL]BUTYRAMIDE; PROTEIN PATCHED 1; RAPAMYCIN; SARIDEGIB; SMOOTHENED PROTEIN; SMOOTHENED PROTEIN ANTAGONIST; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; VISMODEGIB; XL 139;

ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CELL PROLIFERATION; DISEASE FREE SURVIVAL; DRUG POTENTIATION; EPITHELIUM CELL; FIBROBLAST; GENE CONTROL; GENE EXPRESSION; HUMAN; METASTASIS; NERVE CELL PLASTICITY; NONHUMAN; PANCREAS CANCER; PANCREATITIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

CARCINOMA, PANCREATIC DUCTAL; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DEOXYCYTIDINE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; NEURONAL PLASTICITY; PARACRINE COMMUNICATION; TUMOR MICROENVIRONMENT;

ERINACEIDAE;

EID: 84865626128     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevEukarGeneExpr.v22.i2.20     Document Type: Article

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