Non-canonical activation of GLI transcription factors: Implications for targeted anti-cancer therapy

Cell Cycle

Volumn 6, Issue 20, 2007, Pages 2458-2463

  Lauth, Matthias ^a   Toftgård, Rune ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cancer formation; Cyclopamine; Drug development; GLI; GLI antagonists; Hedgehog signaling; Metastasis; Ras; Sonic hedgehog; TGF

Indexed keywords

CYCLOPAMINE; G PROTEIN COUPLED RECEPTOR; LIGAND; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI INHIBITOR; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

CANCER CHEMOTHERAPY; CARCINOGENESIS; CLINICAL TRIAL; DOWNSTREAM PROCESSING; GLIOMA; HEDGEHOG; HUMAN; MAMMALIAN GENETICS; MEDULLOBLASTOMA; METASTASIS; NONHUMAN; PARACRINE SIGNALING; REVIEW; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL;

ERINACEIDAE;

EID: 35848938488     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.6.20.4808     Document Type: Review

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