Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to G i proteins

Science Signaling

Volumn 4, Issue 200, 2011, Pages

  Polizio, Ariel H ^a   Chinchilla, Pilar ^a   Chen, Xiaolen ^a   Manning, David R ^b   Riobo, Natalia A ^a,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATASE; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SONIC HEDGEHOG PROTEIN; CELL SURFACE RECEPTOR; GLI1 PROTEIN, HUMAN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PATCHED RECEPTORS; RAC1 PROTEIN, HUMAN; REPRESSOR PROTEIN; RHOA PROTEIN, HUMAN; SHH PROTEIN, HUMAN; SMO PROTEIN, HUMAN; SUFU PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

CELL MIGRATION; CONFERENCE PAPER; ENDOTHELIUM CELL; FIBROBLAST; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; TRANSCRIPTION INITIATION; ANIMAL; CELL DEATH; CELL MOTION; CYTOLOGY; CYTOSKELETON; ENZYME ACTIVATION; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVIEW; SIGNAL TRANSDUCTION;

ERINACEIDAE; VERTEBRATA;

ANIMALS; CELL DEATH; CELL MOVEMENT; CYTOSKELETON; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FIBROBLASTS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEDGEHOG PROTEINS; HUMANS; PROTEIN STRUCTURE, TERTIARY; RAC1 GTP-BINDING PROTEIN; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; REPRESSOR PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 81855183838     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002396     Document Type: Conference Paper

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