Nos2 inactivation promotes the development of medulloblastoma in ptch1 +/- mice by deregulation of Gap43-dependent granule cell precursor migration

PLoS Genetics

Volumn 8, Issue 3, 2012, Pages

  Haag, Daniel ^a   Zipper, Petra ^b   Westrich, Viola ^b   Karra, Daniela ^b   Pfleger, Karin ^a   Toedt, Grischa ^a   Blond, Frederik ^a   Delhomme, Nicolas ^a   Hahn, Meinhard ^a   Reifenberger, Julia ^b   Reifenberger, Guido ^b   Lichter, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROMODULIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; CELL SURFACE RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; PATCHED RECEPTORS; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL MIGRATION; CELL PROLIFERATION; CEREBELLUM; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; ENZYME INACTIVATION; GENE EXPRESSION PROFILING; GENOTYPE; GRANULE CELL; GRANULE CELL PRECURSOR; IMMUNOFLUORESCENCE; MEDULLOBLASTOMA; MOLECULAR MECHANICS; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PROTEIN DEFICIENCY; PTCH1 GENE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; CELL MOTION; CELL TRANSFORMATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOUSE MUTANT; STEM CELL;

ERINACEIDAE; MUS;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CEREBELLUM; GAP-43 PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; MEDULLOBLASTOMA; MICE; MICE, MUTANT STRAINS; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84859259642     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002572     Document Type: Article

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