메뉴 건너뛰기




Volumn 5, Issue 1, 2006, Pages 111-117

Hedgehog signaling in human hepatocellular carcinoma

Author keywords

Cyclopamine; HCC; Hedgehog

Indexed keywords

CYCLIN D; CYCLOPAMINE; HEDGEHOG INTERACTING PROTEIN 1; MYC PROTEIN; PROTEIN; SMOOTHENED TRANSMEMBRANE PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG;

EID: 32544437230     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.1.2379     Document Type: Article
Times cited : (92)

References (48)
  • 1
    • 0035467993 scopus 로고    scopus 로고
    • Global cancer statistics in the year 2000
    • Parkin DM. Global cancer statistics in the year 2000. Lancet Oncol 2001; 2:533-43.
    • (2001) Lancet Oncol , vol.2 , pp. 533-543
    • Parkin, D.M.1
  • 2
    • 0023933449 scopus 로고
    • Hepatitis B virus. The major etiology of hepatocellular carcinoma
    • Beasley RP. Hepatitis B virus. The major etiology of hepatocellular carcinoma. Cancer 1988; 61:1942-56.
    • (1988) Cancer , vol.61 , pp. 1942-1956
    • Beasley, R.P.1
  • 4
    • 0034722741 scopus 로고    scopus 로고
    • Risk factors for the rising rates of primary liver cancer in the United States
    • El-Serag HB and Mason AC. Risk factors for the rising rates of primary liver cancer in the United States. Arch Intern Med 2000; 160:3227-30.
    • (2000) Arch Intern Med , vol.160 , pp. 3227-3230
    • El-Serag, H.B.1    Mason, A.C.2
  • 5
    • 0033867475 scopus 로고    scopus 로고
    • Genetics of hepatocellular carcinoma
    • Buendia MA. Genetics of hepatocellular carcinoma. Semin Cancer Biol 2000; 10:185-200.
    • (2000) Semin Cancer Biol , vol.10 , pp. 185-200
    • Buendia, M.A.1
  • 6
    • 0023611945 scopus 로고
    • Role of surgery in the treatment of primary carcinoma of the liver: A 31-year experience
    • Lin TY, Lee CS, Chen KM and Chen CC. Role of surgery in the treatment of primary carcinoma of the liver: a 31-year experience. Br J Surg 1987; 74:839-42.
    • (1987) Br J Surg , vol.74 , pp. 839-842
    • Lin, T.Y.1    Lee, C.S.2    Chen, K.M.3    Chen, C.C.4
  • 8
    • 0032532086 scopus 로고    scopus 로고
    • Treatment of hepatocellular carcinoma associated with cirrhosis in the era of liver transplantation
    • Mor E, Kaspa RT, Sheiner P and SchwartzM. Treatment of hepatocellular carcinoma associated with cirrhosis in the era of liver transplantation. Ann Intern Med 1998; 129:643-53.
    • (1998) Ann Intern Med , vol.129 , pp. 643-653
    • Mor, E.1    Kaspa, R.T.2    Sheiner, P.3    Schwartz, M.4
  • 9
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nusslein-Volhard C and Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature 1980; 287:795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 10
    • 0142227025 scopus 로고    scopus 로고
    • Developmental biology informs cancer: The emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers
    • Xie K and Abbruzzese JL. Developmental biology informs cancer: the emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers. Cancer Cell 2003; 4:245-7.
    • (2003) Cancer Cell , vol.4 , pp. 245-247
    • Xie, K.1    Abbruzzese, J.L.2
  • 11
    • 0037390802 scopus 로고    scopus 로고
    • How a Hedgehog might see holoprosencephaly
    • Roessler E and Muenke M. How a Hedgehog might see holoprosencephaly. Hum Mol Genet 2003; 12:R15-25.
    • (2003) Hum Mol Genet , vol.12
    • Roessler, E.1    Muenke, M.2
  • 12
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: Tumours, embryos and stem cells
    • Ruiz i Altaba A, Sanchez P and Dahmane N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer 2002; 2:361-72.
    • (2002) Nat Rev Cancer , vol.2 , pp. 361-372
    • Ruiz I Altaba, A.1    Sanchez, P.2    Dahmane, N.3
  • 13
    • 0036778132 scopus 로고    scopus 로고
    • Hedgehog signal transduction: Recent findings
    • Nybakken K and Perrimon N. Hedgehog signal transduction: recent findings. Curr Opin Genet Dev 2002; 12:503-11.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 503-511
    • Nybakken, K.1    Perrimon, N.2
  • 14
    • 0036899614 scopus 로고    scopus 로고
    • Pathways and consequences: Hedgehog signaling in human disease
    • Mullor JL, Sanchez P and Altaba AR. Pathways and consequences: Hedgehog signaling in human disease. Trends Cell Biol 2002; 12:562-9.
    • (2002) Trends Cell Biol , vol.12 , pp. 562-569
    • Mullor, J.L.1    Sanchez, P.2    Altaba, A.R.3
  • 15
    • 0032780648 scopus 로고    scopus 로고
    • The patched signaling pathway in tumorigenesis and development: Lessons from animal models
    • Hahn H, Wojnowski L, Miller G and Zimmer A. The patched signaling pathway in tumorigenesis and development: lessons from animal models. J Mol Med 1999; 77:459-68.
    • (1999) J Mol Med , vol.77 , pp. 459-468
    • Hahn, H.1    Wojnowski, L.2    Miller, G.3    Zimmer, A.4
  • 16
    • 0142153787 scopus 로고    scopus 로고
    • The hedgehog signaling network
    • Cohen MM Jr. The hedgehog signaling network. Am J Med Genet 2003; 123A:5-28.
    • (2003) Am J Med Genet , vol.123 A , pp. 5-28
    • Cohen Jr., M.M.1
  • 17
    • 0036471671 scopus 로고    scopus 로고
    • Sonic hedgehog in the nervous system: Functions, modifications and mechanisms
    • Ho KS and Scott MP. Sonic hedgehog in the nervous system: functions, modifications and mechanisms. Curr Opin Neurobiol 2002; 12:57-63.
    • (2002) Curr Opin Neurobiol , vol.12 , pp. 57-63
    • Ho, K.S.1    Scott, M.P.2
  • 20
    • 0036363951 scopus 로고    scopus 로고
    • Hedgehog-Gli signalling and the growth of the brain
    • Ruiz AA I, Palma V and Dahmane N. Hedgehog-Gli signalling and the growth of the brain. Nat Rev Neurosci 2002; 3:24-33.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 24-33
    • Ruiz I, A.A.1    Palma, V.2    Dahmane, N.3
  • 21
    • 0033580269 scopus 로고    scopus 로고
    • Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
    • Chuang PT and McMahon AP. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature 1999; 397:617-21.
    • (1999) Nature , vol.397 , pp. 617-621
    • Chuang, P.T.1    McMahon, A.P.2
  • 23
    • 13144298531 scopus 로고    scopus 로고
    • Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors
    • Olsen CL, Hsu PP, Glienke J, Rubanyi GM and Brooks AR. Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors. BMC Cancer 2004; 4:43.
    • (2004) BMC Cancer , vol.4 , pp. 43
    • Olsen, C.L.1    Hsu, P.P.2    Glienke, J.3    Rubanyi, G.M.4    Brooks, A.R.5
  • 24
    • 0030844141 scopus 로고    scopus 로고
    • Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
    • Dahmane N, Lee J, Robins P, Heller P and Ruiz i Altaba A. Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 1997; 389:876-81.
    • (1997) Nature , vol.389 , pp. 876-881
    • Dahmane, N.1    Lee, J.2    Robins, P.3    Heller, P.4    Ruiz I Altaba, A.5
  • 26
    • 1042278781 scopus 로고    scopus 로고
    • Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma
    • Williams JA. Hedgehog signaling pathway as a target for therapeutic intervention in basal cell carcinoma. Drug News Perspect 2003; 16:657-62.
    • (2003) Drug News Perspect , vol.16 , pp. 657-662
    • Williams, J.A.1
  • 27
    • 6344250799 scopus 로고    scopus 로고
    • Patched/Sonic Hedgehog pathway and basal cell carcinoma
    • Basset-Seguin N and Soufir N. Patched/Sonic Hedgehog pathway and basal cell carcinoma. Med Sci 2004; 20:899-903.
    • (2004) Med Sci , vol.20 , pp. 899-903
    • Basset-Seguin, N.1    Soufir, N.2
  • 31
    • 0242669237 scopus 로고    scopus 로고
    • Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
    • Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA and Baylin SB. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 2003; 422:313-7.
    • (2003) Nature , vol.422 , pp. 313-317
    • Watkins, D.N.1    Berman, D.M.2    Burkholder, S.G.3    Wang, B.4    Beachy, P.A.5    Baylin, S.B.6
  • 40
    • 0033775615 scopus 로고    scopus 로고
    • Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
    • Bustin SA. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 2000; 25:169-93.
    • (2000) J Mol Endocrinol , vol.25 , pp. 169-193
    • Bustin, S.A.1
  • 43
    • 0036829397 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
    • Chen JK, Taipale J, Cooper MK and Beachy PA. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev 2002; 16:2743-8.
    • (2002) Genes Dev , vol.16 , pp. 2743-2748
    • Chen, J.K.1    Taipale, J.2    Cooper, M.K.3    Beachy, P.A.4
  • 45
    • 0032919172 scopus 로고    scopus 로고
    • Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: Relationship to disease stage, tumor size, and cirrhosis
    • Wong N, Lai P, Lee SW, Fan S, Pang E, Liew CT, Sheng Z, Lau JW and Johnson PJ. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis. Am J Pathol 1999; 154:37-43.
    • (1999) Am J Pathol , vol.154 , pp. 37-43
    • Wong, N.1    Lai, P.2    Lee, S.W.3    Fan, S.4    Pang, E.5    Liew, C.T.6    Sheng, Z.7    Lau, J.W.8    Johnson, P.J.9
  • 46
    • 0032898742 scopus 로고    scopus 로고
    • Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization
    • Zimonjic DB, Keck CL, Thorgeirsson SS and Popescu NC. Novel recurrent genetic imbalances in human hepatocellular carcinoma cell lines identified by comparative genomic hybridization. Hepatology 1999; 29:1208-14.
    • (1999) Hepatology , vol.29 , pp. 1208-1214
    • Zimonjic, D.B.1    Keck, C.L.2    Thorgeirsson, S.S.3    Popescu, N.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.