The sonic hedgehog-GLI1 signaling pathway in brain tumor development

Expert Opinion on Therapeutic Targets

Volumn 16, Issue 12, 2012, Pages 1227-1238

  Shahi, Mehdi H ^a   Rey, Juan A ^b   Castresana, Javier S ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^c UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Astrocytoma; Brain tumors; Cancer stem cells; GLI1; Glioma; Medulloblastoma; Neuroblastoma; PTCH; SMO; Sonic hedgehog

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BMI1 PROTEIN; CYCLIN D2; CYCLOPAMINE; GLYCOPROTEIN; HEDGEHOG INTERACTING PROTEIN; PLAKOGLOBIN; PROTEIN PATCHED 1; SCAFFOLD PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SMALL INTERFERING RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; SUPPRESSOR OF FUSED PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ASTROCYTOMA; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; BRAIN TUMOR; BREAST CANCER; CANCER RECURRENCE; CANCER RESISTANCE; CANCER STEM CELL; CARCINOGENESIS; CELL MEMBRANE; CELL NUCLEUS; CHRONIC LYMPHATIC LEUKEMIA; DESMOPLASTIC MEDULLOBLASTOMA; ESOPHAGUS CANCER; EWING SARCOMA; HUMAN; LARGE CELL LYMPHOMA; MALIGNANT NEOPLASTIC DISEASE; MEDULLOBLASTOMA; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN NEOPLASMS; HEDGEHOG PROTEINS; HUMANS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84869382484     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2012.720975     Document Type: Review

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