Sox9 drives columnar differentiation of esophageal squamous epithelium: A possible role in the pathogenesis of Barrett's esophagus

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 12, 2012, Pages

  Clemons, Nicholas J ^a,b   Wang, David H ^c   Croagh, Daniel ^a,b   Tikoo, Anjali ^a,b   Fennell, Christina M ^a   Murone, Carmel ^d   Scott, Andrew M ^d   Neil Watkins, D ^e   Phillips, Wayne A ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

Barrett's esophagus; Bone morphogenetic protein 4; Columnar metaplasia; Sonic hedgehog; Sox9

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CYTOKERATIN 8; GLYCOPROTEIN; INTESTINAL SPECIFIC GLYCOPROTEIN A33; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; ESOPHAGUS MUCOSA; ESOPHAGUS SQUAMOUS EPITHELIUM; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BARRETT ESOPHAGUS; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE SUSCEPTIBILITY; EPITHELIAL CELLS; EPITHELIUM; ESOPHAGUS; HUMANS; MICE; MICE, INBRED C57BL; SOX9 TRANSCRIPTION FACTOR;

EID: 84871336830     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00291.2012     Document Type: Article

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