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Volumn 29, Issue 2, 2013, Pages 146-152

Indoleamine 2,3 dioxygenase in intestinal disease

Author keywords

biomarker; cancer; colitis; IDO; kynurenine; tryptophan

Indexed keywords

ABATACEPT; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INTERLEUKIN 27; KYNURENINE; TOLL LIKE RECEPTOR 9; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 84873413184     PISSN: 02671379     EISSN: 15317056     Source Type: Journal    
DOI: 10.1097/MOG.0b013e32835c9cb3     Document Type: Review
Times cited : (108)

References (70)
  • 1
    • 34249295962 scopus 로고    scopus 로고
    • Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
    • Ball HJ, Sanchez-Perez A, Weiser S, et al. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene 2007; 396:203-213.
    • (2007) Gene , vol.396 , pp. 203-213
    • Ball, H.J.1    Sanchez-Perez, A.2    Weiser, S.3
  • 2
    • 34547643025 scopus 로고    scopus 로고
    • Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    • Metz R, Duhadaway JB, Kamasani U, et al. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res 2007; 67:7082-7087.
    • (2007) Cancer Res , vol.67 , pp. 7082-7087
    • Metz, R.1    Duhadaway, J.B.2    Kamasani, U.3
  • 3
    • 84872015298 scopus 로고    scopus 로고
    • Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: The absence of IDO1 upregulates IDO2 expression in the epididymis
    • Fukunaga M, Yamamoto Y, Kawasoe M, et al. Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: The absence of IDO1 upregulates IDO2 expression in the epididymis. J Histochem Cytochem 2012.
    • (2012) J Histochem Cytochem
    • Fukunaga, M.1    Yamamoto, Y.2    Kawasoe, M.3
  • 4
    • 84868220730 scopus 로고    scopus 로고
    • Tryptophan catabolism in cancer: Beyond IDO and tryptophan depletion
    • Platten M, Wick W, Van den Eynde BJ. Tryptophan catabolism in cancer: Beyond IDO and tryptophan depletion. Cancer Res 2012; 72:5435-5440.
    • (2012) Cancer Res , vol.72 , pp. 5435-5440
    • Platten, M.1    Wick, W.2    Van Den Eynde, B.J.3
  • 5
    • 80054041992 scopus 로고    scopus 로고
    • An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    • Opitz CA, Litzenburger UM, Sahm F, et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 2011; 478:197-203.
    • (2011) Nature , vol.478 , pp. 197-203
    • Opitz, C.A.1    Litzenburger, U.M.2    Sahm, F.3
  • 6
    • 0033519278 scopus 로고    scopus 로고
    • Inhibition of T cell proliferation by macrophage tryptophan catabolism
    • Munn DH, Shafizadeh E, Attwood JT, et al. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med 1999; 189:1363-1372.
    • (1999) J Exp Med , vol.189 , pp. 1363-1372
    • Munn, D.H.1    Shafizadeh, E.2    Attwood, J.T.3
  • 7
    • 0032555614 scopus 로고    scopus 로고
    • Prevention of allogeneic fetal rejection by tryptophan catabolism
    • Munn DH, ZhouM, Attwood JT, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998; 281:1191-1193.
    • (1998) Science , vol.28 , pp. 11191-1193
    • Munn, D.H.1    Zhou, M.2    Attwood, J.T.3
  • 8
    • 80052020183 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
    • Pallotta MT, Orabona C, Volpi C, et al. Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol 2011; 12:870-878.
    • (2011) Nat Immunol , vol.12 , pp. 870-878
    • Pallotta, M.T.1    Orabona, C.2    Volpi, C.3
  • 9
    • 0036244045 scopus 로고    scopus 로고
    • Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: Implications for inflammatory bowel diseases
    • Barcelo-Batllori S, Andre M, Servis C, et al. Proteomic analysis of cytokine induced proteins in human intestinal epithelial cells: Implications for inflammatory bowel diseases. Proteomics 2002; 2:551-560.
    • (2002) Proteomics , vol.2 , pp. 551-560
    • Barcelo-Batllori, S.1    Andre, M.2    Servis, C.3
  • 10
    • 47249131189 scopus 로고    scopus 로고
    • Inflamed intestinal mucosa features a specific epithelial expression pattern of indoleamine 2,3-dioxygenase
    • Ferdinande L, Demetter P, Perez-Novo C, et al. Inflamed intestinal mucosa features a specific epithelial expression pattern of indoleamine 2,3-dioxygenase. Int J Immunopathol Pharmacol 2008; 21:289-295.
    • (2008) Int J Immunopathol Pharmacol , vol.21 , pp. 289-295
    • Ferdinande, L.1    Demetter, P.2    Perez-Novo, C.3
  • 11
    • 0034626682 scopus 로고    scopus 로고
    • Analysis of mucosal gene expression in inflammatory bowel disease by parallel oligonucleotide arrays
    • Dieckgraefe BK, Stenson WF, Korzenik JR, et al. Analysis of mucosal gene expression in inflammatory bowel disease by parallel oligonucleotide arrays. Physiol Genomics 2000; 4:1-11.
    • (2000) Physiol Genomics , vol.4 , pp. 1-11
    • Dieckgraefe, B.K.1    Stenson, W.F.2    Korzenik, J.R.3
  • 12
    • 6044219766 scopus 로고    scopus 로고
    • Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease
    • Wolf AM, Wolf D, Rumpold H, et al. Overexpression of indoleamine 2,3-dioxygenase in human inflammatory bowel disease. Clin Immunol 2004; 113:47-55.
    • (2004) Clin Immunol , vol.113 , pp. 47-55
    • Wolf, A.M.1    Wolf, D.2    Rumpold, H.3
  • 13
    • 67650225283 scopus 로고    scopus 로고
    • Gene expression patterns in experimental colitis in IL-10-deficient mice
    • Hansen JJ, Holt L, Sartor RB. Gene expression patterns in experimental colitis in IL-10-deficient mice. Inflamm Bowel Dis 2009; 15:890-899.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 890-899
    • Hansen, J.J.1    Holt, L.2    Sartor, R.B.3
  • 14
    • 0345490963 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice
    • Gurtner GJ, Newberry RD, Schloemann SR, et al. Inhibition of indoleamine 2,3-dioxygenase augments trinitrobenzene sulfonic acid colitis in mice. Gastroenterology 2003; 125:1762-1773.
    • (2003) Gastroenterology , vol.125 , pp. 1762-1773
    • Gurtner, G.J.1    Newberry, R.D.2    Schloemann, S.R.3
  • 15
    • 77951737056 scopus 로고    scopus 로고
    • Gut CD103 dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction
    • Matteoli G, Mazzini E, Iliev ID, et al. Gut CD103 dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction. Gut 2010; 59:595-604.
    • (2010) Gut , vol.59 , pp. 595-604
    • Matteoli, G.1    Mazzini, E.2    Iliev, I.D.3
  • 16
    • 84863230541 scopus 로고    scopus 로고
    • Goblet cells deliver luminal antigen to CD103 dendritic cells in the small intestine
    • McDole JR, Wheeler LW, McDonald KG, et al. Goblet cells deliver luminal antigen to CD103 dendritic cells in the small intestine. Nature 2012; 483:345-349.
    • (2012) Nature , vol.483 , pp. 345-349
    • McDole, J.R.1    Wheeler, L.W.2    McDonald, K.G.3
  • 17
    • 79952604556 scopus 로고    scopus 로고
    • Regulation of colonic epithelial cell turnover by IDO contributes to the innate susceptibility of SCID mice to Trichuris muris infection
    • Bell LV, Else KJ. Regulation of colonic epithelial cell turnover by IDO contributes to the innate susceptibility of SCID mice to Trichuris muris infection. Parasite Immunol 2011; 33:244-249.
    • (2011) Parasite Immunol , vol.33 , pp. 244-249
    • Bell, L.V.1    Else, K.J.2
  • 18
    • 77951635953 scopus 로고    scopus 로고
    • Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis
    • Ciorba MA, Bettonville EE, McDonald KG, et al. Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis. J Immunol 2010; 184:3907-3916.
    • (2010) J Immunol , vol.184 , pp. 3907-3916
    • Ciorba, M.A.1    Bettonville, E.E.2    McDonald, K.G.3
  • 19
    • 42449097698 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality
    • Jasperson LK, Bucher C, Panoskaltsis-Mortari A, et al. Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality. Blood 2008; 111:3257-3265.
    • (2008) Blood , vol.111 , pp. 3257-3265
    • Jasperson, L.K.1    Bucher, C.2    Panoskaltsis-Mortari, A.3
  • 20
    • 73949103808 scopus 로고    scopus 로고
    • Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
    • Jasperson LK, Bucher C, Panoskaltsis-Mortari A, et al. Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood 2009; 114:5062-5070.
    • (2009) Blood , vol.114 , pp. 5062-5070
    • Jasperson, L.K.1    Bucher, C.2    Panoskaltsis-Mortari, A.3
  • 21
    • 46449090988 scopus 로고    scopus 로고
    • Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis
    • Harrington L, Srikanth CV, Antony R, et al. Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis. Infect Immun 2008; 76:3045-3053.
    • (2008) Infect Immun , vol.76 , pp. 3045-3053
    • Harrington, L.1    Srikanth, C.V.2    Antony, R.3
  • 22
    • 70449727864 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation
    • Cherayil BJ. Indoleamine 2,3-dioxygenase in intestinal immunity and inflammation. Inflamm Bowel Dis 2009; 15:1391-1396.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1391-1396
    • Cherayil, B.J.1
  • 23
    • 14644403009 scopus 로고    scopus 로고
    • Toll-like receptor 9-induced type I IFN protects mice from experimental colitis
    • Katakura K, Lee J, Rachmilewitz D, et al. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest 2005; 115:695-702.
    • (2005) J Clin Invest , vol.115 , pp. 695-702
    • Katakura, K.1    Lee, J.2    Rachmilewitz, D.3
  • 24
    • 70349320134 scopus 로고    scopus 로고
    • Anti-CTLA-4 treatment induces IL-10-producing ICOS regulatory T cells displaying IDO-dependent antiinflammatory properties in a mouse model of colitis
    • Coquerelle C, Oldenhove G, Acolty V, et al. Anti-CTLA-4 treatment induces IL-10-producing ICOS regulatory T cells displaying IDO-dependent antiinflammatory properties in a mouse model of colitis. Gut 2009; 58:1363-1373.
    • (2009) Gut , vol.58 , pp. 1363-1373
    • Coquerelle, C.1    Oldenhove, G.2    Acolty, V.3
  • 25
    • 37249033780 scopus 로고    scopus 로고
    • Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction
    • Davis PM, Nadler SG, Stetsko DK, Suchard SJ. Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction. Clin Immunol 2008; 126:38-47.
    • (2008) Clin Immunol , vol.126 , pp. 38-47
    • Davis, P.M.1    Nadler, S.G.2    Stetsko, D.K.3    Suchard, S.J.4
  • 26
  • 27
    • 0037090313 scopus 로고    scopus 로고
    • Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses
    • Mellor AL, Keskin DB, Johnson T, et al. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. J Immunol 2002; 168:3771-3776.
    • (2002) J Immunol , vol.168 , pp. 3771-3776
    • Mellor, A.L.1    Keskin, D.B.2    Johnson, T.3
  • 28
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor AL, Munn DH. IDO expression by dendritic cells: Tolerance and tryptophan catabolism. Nat Rev Immunol 2004; 4:762-774.
    • (2004) Nat Rev Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 29
    • 27144552597 scopus 로고    scopus 로고
    • Cutting edge: CpG oligonucleotides induce splenic CD19 dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling
    • Mellor AL, Baban B, Chandler PR, et al. Cutting edge: CpG oligonucleotides induce splenic CD19 dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling. J Immunol 2005; 175:5601-5605.
    • (2005) J Immunol , vol.175 , pp. 5601-5605
    • Mellor, A.L.1    Baban, B.2    Chandler, P.R.3
  • 30
    • 84862174198 scopus 로고    scopus 로고
    • Serum analysis of tryptophan catabolism pathway: Correlation with Crohn's disease activity
    • Gupta NK, Thaker AI, Kanuri N, et al. Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity. Inflamm Bowel Dis 2012; 18:1214-1220.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1214-1220
    • Gupta, N.K.1    Thaker, A.I.2    Kanuri, N.3
  • 31
    • 34247202224 scopus 로고    scopus 로고
    • Role of indoleamine 2,3-dioxygenase in antimicrobial defence and immuno-regulation: Tryptophan depletion versus production of toxic kynurenines
    • MacKenzie CR, Heseler K, Muller A, Daubener W. Role of indoleamine 2,3-dioxygenase in antimicrobial defence and immuno-regulation: Tryptophan depletion versus production of toxic kynurenines. Curr Drug Metab 2007; 8:237-244.
    • (2007) Curr Drug Metab , vol.8 , pp. 237-244
    • MacKenzie, C.R.1    Heseler, K.2    Muller, A.3    Daubener, W.4
  • 32
    • 33845995125 scopus 로고    scopus 로고
    • Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
    • Zeissig S, Burgel N, Gunzel D, et al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 2007; 56:61-72.
    • (2007) Gut , vol.56 , pp. 61-72
    • Zeissig, S.1    Burgel, N.2    Gunzel, D.3
  • 33
    • 84855272274 scopus 로고    scopus 로고
    • A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins
    • Diegelmann J, Olszak T, Goke B, et al. A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins. J Biol Chem 2012; 287:286-298.
    • (2012) J Biol Chem , vol.287 , pp. 286-298
    • Diegelmann, J.1    Olszak, T.2    Goke, B.3
  • 34
    • 84864270714 scopus 로고    scopus 로고
    • ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
    • Hashimoto T, Perlot T, Rehman A, et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature 2012; 487:477-481.
    • (2012) Nature , vol.487 , pp. 477-481
    • Hashimoto, T.1    Perlot, T.2    Rehman, A.3
  • 35
    • 84858386087 scopus 로고    scopus 로고
    • Biomarkers in inflammatory bowel disease: Current practices and recent advances
    • Iskandar HN, Ciorba MA. Biomarkers in inflammatory bowel disease: current practices and recent advances. Transl Res 2012; 159:313-325.
    • (2012) Transl Res , vol.159 , pp. 313-325
    • Iskandar, H.N.1    Ciorba, M.A.2
  • 36
    • 79951664238 scopus 로고    scopus 로고
    • Biological markers in inflammatory bowel disease: Practical consideration for clinicians
    • Mendoza JL, Abreu MT. Biological markers in inflammatory bowel disease: practical consideration for clinicians. Gastroenterol Clin Biol 2009; 33 (Suppl. 3):S158-S173.
    • (2009) Gastroenterol Clin Biol , vol.33 , Issue.SUPPL. 3
    • Mendoza, J.L.1    Abreu, M.T.2
  • 38
    • 34247872887 scopus 로고    scopus 로고
    • Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease
    • Torres MI, Lopez-Casado MA, Lorite P, Rios A. Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease. Clin Exp Immunol 2007; 148:419-424.
    • (2007) Clin Exp Immunol , vol.148 , pp. 419-424
    • Torres, M.I.1    Lopez-Casado, M.A.2    Lorite, P.3    Rios, A.4
  • 39
    • 0017166692 scopus 로고
    • Serum tryptophan in Crohn's disease
    • Beeken WL. Serum tryptophan in Crohn's disease. Scand J Gastroenterol 1976; 11:735-740.
    • (1976) Scand J Gastroenterol , vol.11 , pp. 735-740
    • Beeken, W.L.1
  • 40
    • 84856420259 scopus 로고    scopus 로고
    • Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease
    • Hisamatsu T, Okamoto S, Hashimoto M, et al. Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease. PLoS One 2012; 7:e31131.
    • (2012) PLoS One , vol.7
    • Hisamatsu, T.1    Okamoto, S.2    Hashimoto, M.3
  • 41
    • 79959895766 scopus 로고    scopus 로고
    • GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium
    • Shiomi Y, Nishiumi S, Ooi M, et al. GCMS-based metabolomic study in mice with colitis induced by dextran sulfate sodium. Inflamm Bowel Dis 2011; 17:2261-2274.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 2261-2274
    • Shiomi, Y.1    Nishiumi, S.2    Ooi, M.3
  • 42
    • 1042268012 scopus 로고    scopus 로고
    • Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease
    • Forrest CM, Gould SR, Darlington LG, Stone TW. Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. Adv Exp Med Biol 2003; 527:395-400.
    • (2003) Adv Exp Med Biol , vol.527 , pp. 395-400
    • Forrest, C.M.1    Gould, S.R.2    Darlington, L.G.3    Stone, T.W.4
  • 43
    • 0036730844 scopus 로고    scopus 로고
    • Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease
    • Forrest CM, Youd P, Kennedy A, et al. Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease. J Biomed Sci 2002; 9:436-442.
    • (2002) J Biomed Sci , vol.9 , pp. 436-442
    • Forrest, C.M.1    Youd, P.2    Kennedy, A.3
  • 44
    • 77950658599 scopus 로고    scopus 로고
    • Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease
    • Lin HM, Barnett MP, Roy NC, et al. Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease. J Proteome Res 2010; 9:1965-1975.
    • (2010) J Proteome Res , vol.9 , pp. 1965-1975
    • Lin, H.M.1    Barnett, M.P.2    Roy, N.C.3
  • 45
    • 65249184431 scopus 로고    scopus 로고
    • Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease
    • Lin HM, Edmunds SI, Helsby NA, et al. Nontargeted urinary metabolite profiling of a mouse model of Crohn's disease. J Proteome Res 2009; 8:2045-2057.
    • (2009) J Proteome Res , vol.8 , pp. 2045-2057
    • Lin, H.M.1    Edmunds, S.I.2    Helsby, N.A.3
  • 46
    • 79251572623 scopus 로고    scopus 로고
    • Identification of urinary biomarkers of colon inflammation in IL10-/- mice using short-column LCMS metabolomics
    • Otter D, Cao M, Lin HM, et al. Identification of urinary biomarkers of colon inflammation in IL10-/- mice using short-column LCMS metabolomics. J Biomed Biotechnol 2011; 2011:974701.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 974701
    • Otter, D.1    Cao, M.2    Lin, H.M.3
  • 48
    • 77953278068 scopus 로고    scopus 로고
    • Value of mucosal assessment and biomarkers in inflammatory bowel disease
    • Stidham RW, Higgins PD. Value of mucosal assessment and biomarkers in inflammatory bowel disease. Expert Rev Gastroenterol Hepatol 2010; 4:285-291.
    • (2010) Expert Rev Gastroenterol Hepatol , vol.4 , pp. 285-291
    • Stidham, R.W.1    Higgins, P.D.2
  • 49
    • 34547503869 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel disease: Results from a Norwegian population-based cohort
    • Froslie KF, Jahnsen J, Moum BA, Vatn MH. Mucosal healing in inflammatory bowel disease: Results from a Norwegian population-based cohort. Gastroenterology 2007; 133:412-422.
    • (2007) Gastroenterology , vol.133 , pp. 412-422
    • Froslie, K.F.1    Jahnsen, J.2    Moum, B.A.3    Vatn, M.H.4
  • 50
    • 84862788118 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease
    • Zhou L, Chen H, Wen Q, Zhang Y. Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease. Eur J Gastroenterol Hepatol 2012; 24:695-701.
    • (2012) Eur J Gastroenterol Hepatol , vol.24 , pp. 695-701
    • Zhou, L.1    Chen, H.2    Wen, Q.3    Zhang, Y.4
  • 51
    • 77951718214 scopus 로고    scopus 로고
    • Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
    • Liu X, Shin N, Koblish HK, et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood 2010; 115:3520-3530.
    • (2010) Blood , vol.115 , pp. 3520-3530
    • Liu, X.1    Shin, N.2    Koblish, H.K.3
  • 52
    • 0037024439 scopus 로고    scopus 로고
    • Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer
    • Huang A, Fuchs D, Widner B, et al. Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. Br J Cancer 2002; 86:1691-1696.
    • (2002) Br J Cancer , vol.86 , pp. 1691-1696
    • Huang, A.1    Fuchs, D.2    Widner, B.3
  • 53
    • 79960278867 scopus 로고    scopus 로고
    • Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells
    • Walczak K, Dabrowski W, Langner E, et al. Kynurenic acid synthesis and kynurenine aminotransferases expression in colon derived normal and cancer cells. Scand J Gastroenterol 2011; 46:903-912.
    • (2011) Scand J Gastroenterol , vol.46 , pp. 903-912
    • Walczak, K.1    Dabrowski, W.2    Langner, E.3
  • 54
    • 84860852600 scopus 로고    scopus 로고
    • Blocking IDO activity to enhance antitumor immunity
    • Munn DH. Blocking IDO activity to enhance antitumor immunity. Front Biosci (Elite Ed) 2012; 4:734-745.
    • (2012) Front Biosci (Elite Ed) , vol.4 , pp. 734-745
    • Munn, D.H.1
  • 55
    • 84855340494 scopus 로고    scopus 로고
    • Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
    • Ferdinande L, Decaestecker C, Verset L, et al. Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer. Br J Cancer 2012; 106:141-147.
    • (2012) Br J Cancer , vol.106 , pp. 141-147
    • Ferdinande, L.1    Decaestecker, C.2    Verset, L.3
  • 56
    • 33644775726 scopus 로고    scopus 로고
    • Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: Effect on tumor-infiltrating T cells
    • Brandacher G, Perathoner A, Ladurner R, et al. Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: Effect on tumor-infiltrating T cells. Clin Cancer Res 2006; 12:1144-1151.
    • (2006) Clin Cancer Res , vol.12 , pp. 1144-1151
    • Brandacher, G.1    Perathoner, A.2    Ladurner, R.3
  • 57
    • 70049096598 scopus 로고    scopus 로고
    • The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer
    • Gao YF, Peng RQ, Li J, et al. The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer. J Transl Med 2009; 7:71.
    • (2009) J Transl Med , vol.7 , pp. 71
    • Gao, Y.F.1    Peng, R.Q.2    Li, J.3
  • 58
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • Uyttenhove C, Pilotte L, Theate I, et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 2003; 9:1269-1274.
    • (2003) Nat Med , vol.9 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3
  • 59
    • 84055184913 scopus 로고    scopus 로고
    • Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase
    • Chang MY, Smith C, Duhadaway JB, et al. Cardiac and gastrointestinal liabilities caused by deficiency in the immune modulatory enzyme indoleamine 2,3-dioxygenase. Cancer Biol Ther 2011; 12:1050-1058.
    • (2011) Cancer Biol Ther , vol.12 , pp. 1050-1058
    • Chang, M.Y.1    Smith, C.2    Duhadaway, J.B.3
  • 60
    • 79960302320 scopus 로고    scopus 로고
    • Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide
    • Macho Fernandez E, Valenti V, Rockel C, et al. Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide. Gut 2011; 60:1050-1059.
    • (2011) Gut , vol.60 , pp. 1050-1059
    • Macho Fernandez, E.1    Valenti, V.2    Rockel, C.3
  • 61
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous Clostridium species
    • Atarashi K, Tanoue T, Shima T, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011; 331:337-341.
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1    Tanoue, T.2    Shima, T.3
  • 62
    • 36849049268 scopus 로고    scopus 로고
    • Toxicology and pharmacokinetics of 1-methyl-D-tryptophan: Absence of toxicity due to saturating absorption
    • Jia L, Schweikart K, Tomaszewski J, et al. Toxicology and pharmacokinetics of 1-methyl-D-tryptophan: Absence of toxicity due to saturating absorption. Food Chem Toxicol 2008; 46:203-211.
    • (2008) Food Chem Toxicol , vol.46 , pp. 203-211
    • Jia, L.1    Schweikart, K.2    Tomaszewski, J.3
  • 63
    • 84873406980 scopus 로고    scopus 로고
    • A phase I study of 1-methyl-Dtryptophan in patients with advanced malignancies
    • suppl.; abstr. 2501)
    • Soliman HH, Neuger A, Noyes D, et al. A phase I study of 1-methyl-Dtryptophan in patients with advanced malignancies. J Clin Oncol 2012; 30(suppl.; abstr. 2501).
    • (2012) J Clin Oncol , vol.30
    • Soliman, H.H.1    Neuger, A.2    Noyes, D.3
  • 64
    • 76649088968 scopus 로고    scopus 로고
    • Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors
    • Koblish HK, Hansbury MJ, Bowman KJ, et al. Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors. Mol Cancer Ther 2010; 9:489-498.
    • (2010) Mol Cancer Ther , vol.9 , pp. 489-498
    • Koblish, H.K.1    Hansbury, M.J.2    Bowman, K.J.3
  • 65
    • 84870426822 scopus 로고    scopus 로고
    • Pharmacodynamic assessment of INCB024360, an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), in advanced cancer patients
    • (abstr. 2500)
    • Newton RC, Scherle PA, Bowman K, et al. Pharmacodynamic assessment of INCB024360, an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), in advanced cancer patients. J Clin Oncol 2012; 30:(abstr. 2500).
    • (2012) J Clin Oncol , vol.30
    • Newton, R.C.1    Scherle, P.A.2    Bowman, K.3
  • 66
    • 84875270910 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and metabolic control of immune responses
    • Munn DH, Mellor AL. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol 2012.
    • (2012) Trends Immunol
    • Munn, D.H.1    Mellor, A.L.2
  • 67
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: When the immune system subjugates the brain
    • Dantzer R, O'Connor JC, Freund GG, et al. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008; 9:46-56.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3
  • 68
    • 64849115090 scopus 로고    scopus 로고
    • Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior
    • O'Connor JC, Lawson MA, Andre C, et al. Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior. J Immunol 2009; 182:3202-3212.
    • (2009) J Immunol , vol.182 , pp. 3202-3212
    • O'Connor, J.C.1    Lawson, M.A.2    Andre, C.3
  • 69
    • 84864772397 scopus 로고    scopus 로고
    • Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression
    • Kim H, Chen L, Lim G, et al. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest 2012; 122:2940-2954.
    • (2012) J Clin Invest , vol.122 , pp. 2940-2954
    • Kim, H.1    Chen, L.2    Lim, G.3
  • 70
    • 0030845613 scopus 로고    scopus 로고
    • Inflammatory bowel disease: A study of the association between anxiety and depression, physical morbidity, and nutritional status
    • Addolorato G, Capristo E, Stefanini GF, Gasbarrini G. Inflammatory bowel disease: A study of the association between anxiety and depression, physical morbidity, and nutritional status. Scand J Gastroenterol 1997; 32:1013-1021.
    • (1997) Scand J Gastroenterol , vol.32 , pp. 1013-1021
    • Addolorato, G.1    Capristo, E.2    Stefanini, G.F.3    Gasbarrini, G.4


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