A better way forward: Targeting hedgehog signaling in liver cancer

Frontiers in Bioscience - Scholar

Volumn 4 S, Issue 1, 2012, Pages 277-286

  Kappler, Roland ^a   Von Schweinitz, Dietrich ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Apoptosis; Hedgehog; Hepatoblastoma; Hepatocellular carcinoma; Inhibitor; Liver cancer; Methylation; Review; Therapy

Indexed keywords

CARBAMOYL PHOSPHATE SYNTHASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOPAMINE; G PROTEIN COUPLED RECEPTOR KINASE 2; GLYCOGEN SYNTHASE KINASE 3BETA; SMOOTHENED PROTEIN; TYROSINE AMINOTRANSFERASE; VISMODEGIB; SONIC HEDGEHOG PROTEIN;

ALCOHOL CONSUMPTION; AMINO TERMINAL SEQUENCE; ARTICLE; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; BILE DUCT CARCINOMA; BILE DUCT LIGATION; BINDING AFFINITY; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL POPULATION; CELL VIABILITY; CPG ISLAND; DNA BINDING; EMBRYO DEVELOPMENT; ENDODERM; FATTY LIVER; FLUORESCENCE ACTIVATED CELL SORTING; GENE MUTATION; GENETIC CONSERVATION; HEDGEHOG; HEPATITIS C; HEPATOBLASTOMA; HIGH THROUGHPUT SCREENING; HOMEOSTASIS; HUMAN; HYPONATREMIA; IN VITRO STUDY; INTRACELLULAR SIGNALING; KNOCKOUT MOUSE; LIVER CANCER; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DEVELOPMENT; LUNG CANCER; MEDULLOBLASTOMA; MENINGIOMA; MOLECULARLY TARGETED THERAPY; NEGATIVE FEEDBACK; NONHUMAN; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PROSTATE CANCER; PROTEIN PHOSPHORYLATION; RHABDOMYOSARCOMA; SIGNAL TRANSDUCTION; STELLATE CELL; STOMACH CANCER; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR GROWTH; ANIMAL; LIVER TUMOR; METABOLISM; PATHOLOGY; REVIEW;

ERINACEIDAE;

ANIMALS; HEDGEHOG PROTEINS; HUMANS; LIVER NEOPLASMS; MOLECULAR TARGETED THERAPY; SIGNAL TRANSDUCTION;

EID: 84869443469     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/s268     Document Type: Article

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