HDAC6 inhibition restores ciliary expression and decreases tumor growth

Cancer Research

Volumn 73, Issue 7, 2013, Pages 2259-2270

  Gradilone, Sergio A ^a   Radtke, Brynn N ^a   Bogert, Pamela S ^a   Huang, Bing Q ^a   Gajdos, Gabriella B ^a   LaRusso, Nicholas F ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HISTONE DEACETYLASE 6; MITOGEN ACTIVATED PROTEIN KINASE; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TUBASTATIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT CARCINOMA; CANCER INHIBITION; CELL PROLIFERATION; CELL REGENERATION; CILIARY BODY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HDAC6 GENE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MALE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ANIMALS; APOPTOSIS; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CHOLANGIOCARCINOMA; CILIA; FLUORESCENT ANTIBODY TECHNIQUE; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; INDOLES; MALE; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84876011387     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2938     Document Type: Article

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