Primary cilia attenuate hedgehog signalling in neoplastic chondrocytes

Oncogene

Volumn 32, Issue 47, 2013, Pages 5388-5396

  Ho, L ^a,b   Ali, S A ^a,b   Al Jazrawe, M ^a,b   Kandel, R ^b,c   Wunder, J S ^b,c   Alman, B A ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Cartilage; Chondrosarcoma; Enchondroma; Hedgehog pathway; Primary cilia

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CANCER INCIDENCE; CARTILAGE CELL; CARTILAGE TUMOR; CELL ORGANELLE; CELL PROLIFERATION; CHONDROSARCOMA; COL2A1 GENE; CONTROLLED STUDY; DEGENERATION; ENCHONDROMA; GENE; GLI2 GENE; GROWTH PLATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IFT88 GENE; MOUSE; NONHUMAN; PHENOTYPE; PRIMARY CILIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR GROWTH;

ANIMALS; APOPTOSIS; BONE NEOPLASMS; CARTILAGE, ARTICULAR; CELL PROLIFERATION; CHONDROCYTES; CHONDROSARCOMA; CILIA; COLLAGEN TYPE II; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

ERINACEIDAE; MUS;

EID: 84888345138     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.588     Document Type: Article

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