Oxysterols and redox signaling in the pathogenesis of non-alcoholic fatty liver disease

Free Radical Research

Volumn 47, Issue 11, 2013, Pages 881-893

  Serviddio, G ^a   Blonda, M ^a   Bellanti, F ^a   Villani, R ^a   Iuliano, L ^b   Vendemiale, G ^a,c  

^a UNIVERSITY OF FOGGIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

Mitochondria; NASH; Oxysterols; Steatosis

Indexed keywords

25 HYDROXYCHOLESTEROL; 7 OXOCHOLESTEROL; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; EPOXIDE HYDROLASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYSTEROL; OZONE; PEROXY RADICAL; PREGNENOLONE; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ATHEROGENESIS; ATHEROSCLEROSIS; AUTOOXIDATION; BILE ACID SYNTHESIS; BIOENERGY; BIOSYNTHESIS; CELL DEATH; CELL VIABILITY; CHOLESTEROL INTAKE; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DNA FRAGMENTATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOTHELIAL DYSFUNCTION; FATTY LIVER; FOOD PROCESSING; GENE EXPRESSION; GENETIC TRANSCRIPTION; GOLGI COMPLEX; HEPATITIS; HUMAN; HUMAN TISSUE; HYDROXYLATION; HYPERLIPIDEMIA; IMMUNOREGULATION; INFLAMMATORY INFILTRATE; INSULIN RESISTANCE; INTRACELLULAR TRANSPORT; JEJUNOILEAL BYPASS; LIPID METABOLISM; LIPID PEROXIDATION; LIPID STORAGE; LIPOGENESIS; LIVER BIOPSY; LIVER FIBROSIS; LIVER INJURY; LIVER MITOCHONDRION; MACROPHAGE; METABOLIC REGULATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MOUSE; NEGATIVE FEEDBACK; NERVE CELL; NERVE DEGENERATION; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGENATION; PATHOGENESIS; RAT; REVIEW; RISK FACTOR; STEROL EXCRETION; STEROL SYNTHESIS; THROMBOCYTE AGGREGATION; TRANSCRIPTION INITIATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; VIRUS HEPATITIS; WEIGHT REDUCTION;

ANIMALS; FATTY LIVER; HUMANS; LIPID METABOLISM; OXIDATION-REDUCTION; RECEPTORS, STEROID; SIGNAL TRANSDUCTION;

EID: 84885897322     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2013.835048     Document Type: Review

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