Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease

Cell Metabolism

Volumn 15, Issue 5, 2012, Pages 665-674

  Min, Hae Ki ^a   Kapoor, Ashwani ^a   Fuchs, Michael ^a   Mirshahi, Faridoddin ^a   Zhou, Huiping ^a   Maher, James ^b   Kellum, John ^b   Warnick, Russell ^c   Contos, Melissa J ^a   Sanyal, Arun J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Health Diagnostics Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE 2; CHOLESTEROL ESTERASE; DESMOSTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR; MICRORNA 34A; SIRTUIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; DOWNSTREAM PROCESSING; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; NONALCOHOLIC FATTY LIVER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; SYNTHESIS; UPREGULATION;

ADENYLATE KINASE; ADULT; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CHOLESTEROL; CHOLESTEROL, LDL; DESMOSTEROL; FATTY LIVER; FEMALE; GENE EXPRESSION; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LIPID METABOLISM; LIVER; MALE; MICRORNAS; MIDDLE AGED; PHENOTYPE; PHOSPHORYLATION; RECEPTORS, LDL; SIRTUIN 1; STEROL ESTERASE; STEROL O-ACYLTRANSFERASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UP-REGULATION;

EID: 84860469242     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.04.004     Document Type: Article

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