The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism

Journal of Steroid Biochemistry and Molecular Biology

Volumn 128, Issue 3-5, 2012, Pages 154-164

  Hessvik, Nina Pettersen ^a   Bakke, Siril Skaret ^a   Smith, Robert ^a   Ravna, Aina Westrheim ^b   Sylte, Ingebrigt ^b   Rustan, Arild Christian ^a   Thoresen, G Hege ^a   Kase, Eili Tranheim ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Human cell models; Lipogenesis; Liver X receptors; Nuclear receptors; Oxysterols

Indexed keywords

22 HYDROXYCHOLESTEROL; FATTY ACID SYNTHASE; GLUCOSE; LINOLEIC ACID; LIPID; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADULT; ARTICLE; CELL STRAIN HEPG2; CELL TYPE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CRYSTAL STRUCTURE; DOWN REGULATION; EXPERIMENTAL MODEL; FATTY ACID OXIDATION; GENE EXPRESSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; LIGAND BINDING; LIPID METABOLISM; LIPOGENESIS; MOLECULAR DOCKING; MYOTUBE; NORMAL HUMAN; PROTEIN DOMAIN; UPREGULATION;

ADIPOCYTES; ANTICHOLESTEREMIC AGENTS; BINDING SITES; CELL LINE; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; ENTEROCYTES; GENE EXPRESSION REGULATION; GLUCOSE; HEPATOCYTES; HUMANS; HYDROXYCHOLESTEROLS; LIPID METABOLISM; MODELS, MOLECULAR; MOLECULAR CONFORMATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY; ORPHAN NUCLEAR RECEPTORS; RNA, MESSENGER; SATELLITE CELLS, SKELETAL MUSCLE;

EID: 84855649098     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.10.006     Document Type: Article

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