-
1
-
-
34447543913
-
Cellular senescence in cancer and aging
-
M. Collado, M.A. Blasco, and M. Serrano Cellular senescence in cancer and aging Cell 130 2007 223 233
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
2
-
-
18044398540
-
Telomeres as biomarkers for ageing and age-related diseases
-
T. von Zglinicki, and C.M. Martin-Ruiz Telomeres as biomarkers for ageing and age-related diseases Curr Mol Med 5 2005 197 203
-
(2005)
Curr Mol Med
, vol.5
, pp. 197-203
-
-
Von Zglinicki, T.1
Martin-Ruiz, C.M.2
-
3
-
-
34548660457
-
Global initiative for chronic obstructive lung disease: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
K.F. Rabe, S. Hurd, and A. Anzueto Global initiative for chronic obstructive lung disease: global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary Am J Respir Crit Care Med 176 2007 532 555
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 532-555
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
-
4
-
-
82755161052
-
Idiopathic pulmonary fibrosis
-
T.E. King Jr., A. Pardo, and M. Selman Idiopathic pulmonary fibrosis Lancet 378 2011 1949 1961
-
(2011)
Lancet
, vol.378
, pp. 1949-1961
-
-
King, Jr.T.E.1
Pardo, A.2
Selman, M.3
-
5
-
-
70350223450
-
Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study
-
J. Koshiol, M. Rotunno, and D. Consonni Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study PLoS One 4 2009 e7380
-
(2009)
PLoS One
, vol.4
, pp. 7380
-
-
Koshiol, J.1
Rotunno, M.2
Consonni, D.3
-
6
-
-
0033983168
-
Lung cancer and cryptogenic fibrosing alveolitis: A population-based cohort study
-
R. Hubbard, A. Venn, S. Lewis, and J. Britton Lung cancer and cryptogenic fibrosing alveolitis: a population-based cohort study Am J Respir Crit Care Med 161 2000 5 8
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 5-8
-
-
Hubbard, R.1
Venn, A.2
Lewis, S.3
Britton, J.4
-
7
-
-
84855614159
-
The pathogenesis of COPD and IPF: Distinct horns of the same devil?
-
M. Chilosi, V. Poletti, and A. Rossi The pathogenesis of COPD and IPF: distinct horns of the same devil? Respir Res 13 2012 3
-
(2012)
Respir Res
, vol.13
, pp. 3
-
-
Chilosi, M.1
Poletti, V.2
Rossi, A.3
-
8
-
-
84865121012
-
Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
-
R. Faner, M. Rojas, W. Macnee, and A. Agustí Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis Am J Respir Crit Care Med 186 2012 306 313
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 306-313
-
-
Faner, R.1
Rojas, M.2
Macnee, W.3
Agustí, A.4
-
9
-
-
70349129549
-
Accelerated lung aging: A novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)
-
W. MacNee Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD) Biochem Soc Trans 37 2009 819 823
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 819-823
-
-
Macnee, W.1
-
10
-
-
80051720737
-
Idiopathic pulmonary fibrosis: Update on genetic discoveries
-
C.K. Garcia Idiopathic pulmonary fibrosis: update on genetic discoveries Proc Am Thorac Soc 8 2011 158 162
-
(2011)
Proc Am Thorac Soc
, vol.8
, pp. 158-162
-
-
Garcia, C.K.1
-
11
-
-
79958788032
-
New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis
-
Q. Ding, T. Luckhardt, and L. Hecker New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis Drugs 71 2011 981 1001
-
(2011)
Drugs
, vol.71
, pp. 981-1001
-
-
Ding, Q.1
Luckhardt, T.2
Hecker, L.3
-
12
-
-
0034133548
-
American Thoracic Society. Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS)
-
American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS) Am J Respir Crit Care Med 161 2000 646 664
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 646-664
-
-
-
13
-
-
0035931973
-
A mutation in the surfactant protein C gene associated with familial interstitial lung disease
-
L.M. Nogee, A.E. Dunbar 3rd, S.E. Wert, F. Askin, A. Hamvas, and J.A. Whitsett A mutation in the surfactant protein C gene associated with familial interstitial lung disease N Engl J Med 344 2001 573 579
-
(2001)
N Engl J Med
, vol.344
, pp. 573-579
-
-
Nogee, L.M.1
Dunbar III, A.E.2
Wert, S.E.3
Askin, F.4
Hamvas, A.5
Whitsett, J.A.6
-
14
-
-
0036570052
-
Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred
-
A.Q. Thomas, K. Lane, and J. Phillips 3rd Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred Am J Respir Crit Care Med 165 2002 1322 1328
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1322-1328
-
-
Thomas, A.Q.1
Lane, K.2
Phillips III, J.3
-
15
-
-
58149159548
-
Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer
-
Y. Wang, P.J. Kuan, and C. Xing Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer Am J Hum Genet 84 2009 52 59
-
(2009)
Am J Hum Genet
, vol.84
, pp. 52-59
-
-
Wang, Y.1
Kuan, P.J.2
Xing, C.3
-
16
-
-
0242690510
-
Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis
-
M. Selman, H.M. Lin, and M. Montaño Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis Hum Genet 113 2003 542 550
-
(2003)
Hum Genet
, vol.113
, pp. 542-550
-
-
Selman, M.1
Lin, H.M.2
Montaño, M.3
-
17
-
-
8544245673
-
Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF
-
W.E. Lawson, S.W. Grant, and V. Ambrosini Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF Thorax 59 2004 977 980
-
(2004)
Thorax
, vol.59
, pp. 977-980
-
-
Lawson, W.E.1
Grant, S.W.2
Ambrosini, V.3
-
18
-
-
33846236874
-
Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias
-
P. Markart, C. Ruppert, and M. Wygrecka Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias Eur Respir J 29 2007 134 137
-
(2007)
Eur Respir J
, vol.29
, pp. 134-137
-
-
Markart, P.1
Ruppert, C.2
Wygrecka, M.3
-
19
-
-
34047188508
-
Telomerase mutations in families with idiopathic pulmonary fibrosis
-
M.Y. Armanios, J.J. Chen, and J.D. Cogan Telomerase mutations in families with idiopathic pulmonary fibrosis N Engl J Med 356 2007 1317 1326
-
(2007)
N Engl J Med
, vol.356
, pp. 1317-1326
-
-
Armanios, M.Y.1
Chen, J.J.2
Cogan, J.D.3
-
20
-
-
34250614359
-
Adult-onset pulmonary fibrosis caused by mutations in telomerase
-
K.D. Tsakiri, J.T. Cronkhite, and P.J. Kuan Adult-onset pulmonary fibrosis caused by mutations in telomerase Proc Natl Acad Sci U S A 104 2007 7552 7557
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7552-7557
-
-
Tsakiri, K.D.1
Cronkhite, J.T.2
Kuan, P.J.3
-
21
-
-
51349113450
-
Short telomeres are a risk factor for idiopathic pulmonary fibrosis
-
J.K. Alder, J.J. Chen, and L. Lancaster Short telomeres are a risk factor for idiopathic pulmonary fibrosis Proc Natl Acad Sci U S A 105 2008 13051 13056
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13051-13056
-
-
Alder, J.K.1
Chen, J.J.2
Lancaster, L.3
-
22
-
-
52749083873
-
Telomere shortening in familial and sporadic pulmonary fibrosis
-
J.T. Cronkhite, C. Xing, and G. Raghu Telomere shortening in familial and sporadic pulmonary fibrosis Am J Respir Crit Care Med 178 2008 729 737
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 729-737
-
-
Cronkhite, J.T.1
Xing, C.2
Raghu, G.3
-
23
-
-
84860882713
-
HTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms
-
A.R. Tsang, H.D. Wyatt, N.S. Ting, and T.L. Beattie hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms Aging Cell 11 2012 482 490
-
(2012)
Aging Cell
, vol.11
, pp. 482-490
-
-
Tsang, A.R.1
Wyatt, H.D.2
Ting, N.S.3
Beattie, T.L.4
-
24
-
-
33744935773
-
The genetic approach in pulmonary fibrosis: Can it provide clues to this complex disease?
-
W.E. Lawson, and J.E. Loyd The genetic approach in pulmonary fibrosis: can it provide clues to this complex disease? Proc Am Thorac Soc 3 2006 345 349
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 345-349
-
-
Lawson, W.E.1
Loyd, J.E.2
-
25
-
-
84872054447
-
Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
-
J.A. Kropski, W.E. Lawson, L.R. Young, and T.S. Blackwell Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis Dis Model Mech 6 2013 9 17
-
(2013)
Dis Model Mech
, vol.6
, pp. 9-17
-
-
Kropski, J.A.1
Lawson, W.E.2
Young, L.R.3
Blackwell, T.S.4
-
27
-
-
70949087815
-
A spectrum of severe familial liver disorders associated with telomerase mutations
-
R.T. Calado, J.A. Regal, and D.E. Kleiner A spectrum of severe familial liver disorders associated with telomerase mutations PLoS One 4 2009 e7926
-
(2009)
PLoS One
, vol.4
, pp. 7926
-
-
Calado, R.T.1
Regal, J.A.2
Kleiner, D.E.3
-
29
-
-
64249090973
-
Dyskeratosis congenita, stem cells and telomeres
-
M. Kirwan, and I. Dokal Dyskeratosis congenita, stem cells and telomeres Biochim Biophys Acta 1792 2009 371 379
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 371-379
-
-
Kirwan, M.1
Dokal, I.2
-
30
-
-
0033518188
-
A telomerase component is defective in the human disease dyskeratosis congenita
-
J.R. Mitchell, E. Wood, and K. Collins A telomerase component is defective in the human disease dyskeratosis congenita Nature 402 1999 551 555
-
(1999)
Nature
, vol.402
, pp. 551-555
-
-
Mitchell, J.R.1
Wood, E.2
Collins, K.3
-
32
-
-
79959282291
-
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
-
L.F. Batista, M.F. Pech, and F.L. Zhong Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells Nature 474 2011 399 402
-
(2011)
Nature
, vol.474
, pp. 399-402
-
-
Batista, L.F.1
Pech, M.F.2
Zhong, F.L.3
-
33
-
-
27644548532
-
Dyskeratosis congenita: A disorder of defective telomere maintenance?
-
A.J. Walne, A. Marrone, and I. Dokal Dyskeratosis congenita: a disorder of defective telomere maintenance? Int J Hematol 82 2005 184 189
-
(2005)
Int J Hematol
, vol.82
, pp. 184-189
-
-
Walne, A.J.1
Marrone, A.2
Dokal, I.3
-
34
-
-
0028412593
-
Dyskeratosis congenita showing usual interstitial pneumonia
-
S. Imokawa, A. Sato, and M. Toyoshima Dyskeratosis congenita showing usual interstitial pneumonia Intern Med 33 1994 226 230
-
(1994)
Intern Med
, vol.33
, pp. 226-230
-
-
Imokawa, S.1
Sato, A.2
Toyoshima, M.3
-
35
-
-
20044379963
-
Usual interstitial pneumonia complicating dyskeratosis congenita
-
J.P. Utz, J.H. Ryu, J.L. Myers, and V.V. Michels Usual interstitial pneumonia complicating dyskeratosis congenita Mayo Clin Proc 80 2005 817 821
-
(2005)
Mayo Clin Proc
, vol.80
, pp. 817-821
-
-
Utz, J.P.1
Ryu, J.H.2
Myers, J.L.3
Michels, V.V.4
-
36
-
-
67749086830
-
Genetic and environmental factors influencing human diseases with telomere dysfunction
-
H. Ly Genetic and environmental factors influencing human diseases with telomere dysfunction Int J Clin Exp Med 2 2009 114 130
-
(2009)
Int J Clin Exp Med
, vol.2
, pp. 114-130
-
-
Ly, H.1
-
37
-
-
77956289135
-
Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations
-
A. Diaz de Leon, J.T. Cronkhite, and A.L. Katzenstein Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations PLoS One 5 2010 e10680
-
(2010)
PLoS One
, vol.5
, pp. 10680
-
-
Diaz De Leon, A.1
Cronkhite, J.T.2
Katzenstein, A.L.3
-
39
-
-
0034530337
-
Telomerase in alveolar epithelial development and repair
-
B. Driscoll, S. Buckley, K.C. Bui, K.D. Anderson, and D. Warburton Telomerase in alveolar epithelial development and repair Am J Physiol Lung Cell Mol Physiol 279 2000 L1191 L1198
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Driscoll, B.1
Buckley, S.2
Bui, K.C.3
Anderson, K.D.4
Warburton, D.5
-
40
-
-
75949125865
-
Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosis
-
D.R. Waisberg, J.V. Barbas-Filho, and E.R. Parra Abnormal expression of telomerase/apoptosis limits type II alveolar epithelial cell replication in the early remodeling of usual interstitial pneumonia/idiopathic pulmonary fibrosis Hum Pathol 41 2010 385 391
-
(2010)
Hum Pathol
, vol.41
, pp. 385-391
-
-
Waisberg, D.R.1
Barbas-Filho, J.V.2
Parra, E.R.3
-
41
-
-
48949119341
-
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection
-
W.E. Lawson, P.F. Crossno, and V.V. Polosukhin Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection Am J Physiol Lung Cell Mol Physiol 294 2008 L1119 L1126
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Lawson, W.E.1
Crossno, P.F.2
Polosukhin, V.V.3
-
42
-
-
79960570500
-
Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs
-
W.E. Lawson, D.S. Cheng, and A.L. Degryse Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs Proc Natl Acad Sci U S A 108 2011 10562 10567
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 10562-10567
-
-
Lawson, W.E.1
Cheng, D.S.2
Degryse, A.L.3
-
43
-
-
13844314302
-
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis
-
M. Plataki, A.V. Koutsopoulos, K. Darivianaki, G. Delides, N.M. Siafakas, and D. Bouros Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis Chest 127 2005 266 274
-
(2005)
Chest
, vol.127
, pp. 266-274
-
-
Plataki, M.1
Koutsopoulos, A.V.2
Darivianaki, K.3
Delides, G.4
Siafakas, N.M.5
Bouros, D.6
-
44
-
-
80052540057
-
Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: Effects of misfolded surfactant protein
-
Q. Zhong, B. Zhou, and D.K. Ann Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein Am J Respir Cell Mol Biol 45 2011 498 509
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 498-509
-
-
Zhong, Q.1
Zhou, B.2
Ann, D.K.3
-
45
-
-
54049115076
-
Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
-
M. Korfei, C. Ruppert, and P. Mahavadi Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis Am J Respir Crit Care Med 178 2008 838 846
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 838-846
-
-
Korfei, M.1
Ruppert, C.2
Mahavadi, P.3
-
46
-
-
79955789007
-
Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs
-
M. Korfei, S. Schmitt, and C. Ruppert Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs J Proteome Res 10 2011 2185 2205
-
(2011)
J Proteome Res
, vol.10
, pp. 2185-2205
-
-
Korfei, M.1
Schmitt, S.2
Ruppert, C.3
-
47
-
-
51049112958
-
Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells
-
E. Jorgensen, A. Stinson, L. Shan, J. Yang, D. Gietl, and A.P. Albino Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells BMC Cancer 8 2008 229
-
(2008)
BMC Cancer
, vol.8
, pp. 229
-
-
Jorgensen, E.1
Stinson, A.2
Shan, L.3
Yang, J.4
Gietl, D.5
Albino, A.P.6
-
48
-
-
42949118737
-
Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach
-
S.G. Kelsen, X. Duan, R. Ji, O. Perez, C. Liu, and S. Merali Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach Am J Respir Cell Mol Biol 38 2008 541 550
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 541-550
-
-
Kelsen, S.G.1
Duan, X.2
Ji, R.3
Perez, O.4
Liu, C.5
Merali, S.6
-
49
-
-
39949085603
-
Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival
-
A. Hengstermann, and T. Müller Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival Free Radic Biol Med 44 2008 1097 1107
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1097-1107
-
-
Hengstermann, A.1
Müller, T.2
-
50
-
-
9744272376
-
Cigarette smoke induces senescence in alveolar epithelial cells
-
T. Tsuji, K. Aoshiba, and A. Nagai Cigarette smoke induces senescence in alveolar epithelial cells Am J Respir Cell Mol Biol 31 2004 643 649
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 643-649
-
-
Tsuji, T.1
Aoshiba, K.2
Nagai, A.3
-
51
-
-
0031030088
-
Cigarette smoking: A risk factor for idiopathic pulmonary fibrosis
-
K.B. Baumgartner, J.M. Samet, C.A. Stidley, T.V. Colby, and J.A. Waldron Cigarette smoking: a risk factor for idiopathic pulmonary fibrosis Am J Respir Crit Care Med 155 1997 242 248
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 242-248
-
-
Baumgartner, K.B.1
Samet, J.M.2
Stidley, C.A.3
Colby, T.V.4
Waldron, J.A.5
-
52
-
-
84857758730
-
Right place, right time: The evolving role of herpesvirus infection as a "second hit" in idiopathic pulmonary fibrosis
-
J.A. Kropski, W.E. Lawson, and T.S. Blackwell Right place, right time: the evolving role of herpesvirus infection as a "second hit" in idiopathic pulmonary fibrosis Am J Physiol Lung Cell Mol Physiol 302 2012 L441 L444
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
-
-
Kropski, J.A.1
Lawson, W.E.2
Blackwell, T.S.3
-
53
-
-
22544487197
-
HHV-8 and EBV are not commonly found in idiopathic pulmonary fibrosis
-
A. Zamò, V. Poletti, and D. Reghellin HHV-8 and EBV are not commonly found in idiopathic pulmonary fibrosis Sarcoidosis Vasc Diffuse Lung Dis 22 2005 123 128
-
(2005)
Sarcoidosis Vasc Diffuse Lung Dis
, vol.22
, pp. 123-128
-
-
Zamò, A.1
Poletti, V.2
Reghellin, D.3
-
54
-
-
84860573175
-
Idiopathic pulmonary fibrosis may be a disease of recurrent, tractional injury to the periphery of the aging lung: A unifying hypothesis regarding etiology and pathogenesis
-
K.O. Leslie Idiopathic pulmonary fibrosis may be a disease of recurrent, tractional injury to the periphery of the aging lung: a unifying hypothesis regarding etiology and pathogenesis Arch Pathol Lab Med 136 2012 591 600
-
(2012)
Arch Pathol Lab Med
, vol.136
, pp. 591-600
-
-
Leslie, K.O.1
-
55
-
-
27144559930
-
Cyclic mechanical strain increases reactive oxygen species production in pulmonary epithelial cells
-
K.E. Chapman, S.E. Sinclair, D. Zhuang, A. Hassid, L.P. Desai, and C.M. Waters Cyclic mechanical strain increases reactive oxygen species production in pulmonary epithelial cells Am J Physiol Lung Cell Mol Physiol 289 2005 L834 L841
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Chapman, K.E.1
Sinclair, S.E.2
Zhuang, D.3
Hassid, A.4
Desai, L.P.5
Waters, C.M.6
-
56
-
-
79961042772
-
Cyclic stretch induces alveolar epithelial barrier dysfunction via calpain-mediated degradation of p120-catenin
-
Y. Wang, R.D. Minshall, D.E. Schwartz, and G. Hu Cyclic stretch induces alveolar epithelial barrier dysfunction via calpain-mediated degradation of p120-catenin Am J Physiol Lung Cell Mol Physiol 301 2011 L197 L206
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
-
-
Wang, Y.1
Minshall, R.D.2
Schwartz, D.E.3
Hu, G.4
-
57
-
-
84882927097
-
Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability
-
N. Davidovich, B.C. Dipaolo, G.G. Lawrence, P. Chhour, N. Yehya, and S.S. Margulies Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability Am J Respir Cell Mol Biol 49 2013 156 164
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 156-164
-
-
Davidovich, N.1
Dipaolo, B.C.2
Lawrence, G.G.3
Chhour, P.4
Yehya, N.5
Margulies, S.S.6
-
58
-
-
72149113857
-
Recent advances and new opportunities in lung mechanobiology
-
D.J. Tschumperlin, F. Boudreault, and F. Liu Recent advances and new opportunities in lung mechanobiology J Biomech 43 2010 99 107
-
(2010)
J Biomech
, vol.43
, pp. 99-107
-
-
Tschumperlin, D.J.1
Boudreault, F.2
Liu, F.3
-
59
-
-
84878221108
-
Heterogeneous distribution of mechanical stress in human lung: A mathematical approach to evaluate abnormal remodeling in IPF
-
Carloni A, Poletti V, Bellomo N, Fermo L, Chilosi M. Heterogeneous distribution of mechanical stress in human lung: a mathematical approach to evaluate abnormal remodeling in IPF. J Theor Biol 2013;332:136-40.
-
(2013)
J Theor Biol
, vol.332
, pp. 136-140
-
-
Carloni, A.1
Poletti, V.2
Bellomo, N.3
Fermo, L.4
Chilosi, M.5
-
60
-
-
65549114494
-
Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate
-
E.J. Arnsdorf, P. Tummala, and C.R. Jacobs Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate PLoS One 4 2009 e5388
-
(2009)
PLoS One
, vol.4
, pp. 5388
-
-
Arnsdorf, E.J.1
Tummala, P.2
Jacobs, C.R.3
-
61
-
-
77951465571
-
Mechanical factors activate beta-catenin-dependent oncogene expression in APC mouse colon
-
J. Whitehead, D. Vignjevic, C. Fütterer, E. Beaurepaire, S. Robine, and E. Farge Mechanical factors activate beta-catenin-dependent oncogene expression in APC mouse colon HFSP J 2 2008 286 294
-
(2008)
HFSP J
, vol.2
, pp. 286-294
-
-
Whitehead, J.1
Vignjevic, D.2
Fütterer, C.3
Beaurepaire, E.4
Robine, S.5
Farge, E.6
-
62
-
-
84856133737
-
Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition
-
N.E. Cabrera-Benítez, M. Parotto, and M. Post Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition Crit Care Med 40 2012 510 517
-
(2012)
Crit Care Med
, vol.40
, pp. 510-517
-
-
Cabrera-Benítez, N.E.1
Parotto, M.2
Post, M.3
-
63
-
-
79955967161
-
Mechanical stretch induces epithelial-mesenchymal transition in alveolar epithelia via hyaluronan activation of innate immunity
-
R.L. Heise, V. Stober, C. Cheluvaraju, J.W. Hollingsworth, and S. Garantziotis Mechanical stretch induces epithelial-mesenchymal transition in alveolar epithelia via hyaluronan activation of innate immunity J Biol Chem 286 2011 17435 17444
-
(2011)
J Biol Chem
, vol.286
, pp. 17435-17444
-
-
Heise, R.L.1
Stober, V.2
Cheluvaraju, C.3
Hollingsworth, J.W.4
Garantziotis, S.5
-
64
-
-
77953501417
-
Mechanical stretching induces osteoprotegerin in differentiating C2C12 precursor cells through noncanonical Wnt pathways
-
H.C. Yu, T.C. Wu, M.R. Chen, S.W. Liu, J.H. Chen, and K.M. Lin Mechanical stretching induces osteoprotegerin in differentiating C2C12 precursor cells through noncanonical Wnt pathways J Bone Miner Res 25 2010 1128 1137
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1128-1137
-
-
Yu, H.C.1
Wu, T.C.2
Chen, M.R.3
Liu, S.W.4
Chen, J.H.5
Lin, K.M.6
-
65
-
-
84886943235
-
Role of TAZ as mediator of Wnt signaling
-
L. Azzolin, F. Zanconato, and S. Bresolin Role of TAZ as mediator of Wnt signaling Cell 151 2012 1443 1456
-
(2012)
Cell
, vol.151
, pp. 1443-1456
-
-
Azzolin, L.1
Zanconato, F.2
Bresolin, S.3
-
66
-
-
84865411430
-
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
-
G. Halder, S. Dupont, and S. Piccolo Transduction of mechanical and cytoskeletal cues by YAP and TAZ Nat Rev Mol Cell Biol 13 2012 591 600
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 591-600
-
-
Halder, G.1
Dupont, S.2
Piccolo, S.3
-
67
-
-
84879094799
-
YAP/TEAD-mediated transcription controls cellular senescence
-
Q. Xie, J. Chen, and H. Feng YAP/TEAD-mediated transcription controls cellular senescence Cancer Res 73 2013 3615 3624
-
(2013)
Cancer Res
, vol.73
, pp. 3615-3624
-
-
Xie, Q.1
Chen, J.2
Feng, H.3
-
68
-
-
0242500879
-
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
-
M. Chilosi, V. Poletti, and A. Zamò Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis Am J Pathol 162 2003 1495 1502
-
(2003)
Am J Pathol
, vol.162
, pp. 1495-1502
-
-
Chilosi, M.1
Poletti, V.2
Zamò, A.3
-
69
-
-
47749101725
-
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis
-
M. Königshoff, N. Balsara, and E.M. Pfaff Functional Wnt signaling is increased in idiopathic pulmonary fibrosis PLoS One 3 2008 e2142
-
(2008)
PLoS One
, vol.3
, pp. 2142
-
-
Königshoff, M.1
Balsara, N.2
Pfaff, E.M.3
-
70
-
-
65249088418
-
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
-
M. Königshoff, M. Kramer, and N. Balsara WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis J Clin Invest 119 2009 772 787
-
(2009)
J Clin Invest
, vol.119
, pp. 772-787
-
-
Königshoff, M.1
Kramer, M.2
Balsara, N.3
-
71
-
-
33750030758
-
The regulation of INK4/ARF in cancer and aging
-
W.Y. Kim, and N.E. Sharpless The regulation of INK4/ARF in cancer and aging Cell 127 2006 265 275
-
(2006)
Cell
, vol.127
, pp. 265-275
-
-
Kim, W.Y.1
Sharpless, N.E.2
-
72
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
J. Campisi Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors Cell 120 2005 513 522
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
73
-
-
34548211521
-
The DNA damage signaling pathway connects oncogenic stress to cellular senescence
-
F.A. Mallette, and G. Ferbeyre The DNA damage signaling pathway connects oncogenic stress to cellular senescence Cell Cycle 6 2007 1831 1836
-
(2007)
Cell Cycle
, vol.6
, pp. 1831-1836
-
-
Mallette, F.A.1
Ferbeyre, G.2
-
74
-
-
45849099050
-
Living on a break: Cellular senescence as a DNA-damage response
-
F. d'Adda di Fagagna Living on a break: cellular senescence as a DNA-damage response Nat Rev Cancer 8 2008 512 522
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 512-522
-
-
D'Adda Di Fagagna, F.1
-
76
-
-
7044231343
-
The p16INK4a-RB pathway: Molecular link between cellular senescence and tumor suppression
-
N. Ohtani, K. Yamakoshi, A. Takahashi, and E. Hara The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression J Med Invest 51 2004 146 153
-
(2004)
J Med Invest
, vol.51
, pp. 146-153
-
-
Ohtani, N.1
Yamakoshi, K.2
Takahashi, A.3
Hara, E.4
-
77
-
-
78549268199
-
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo
-
S. Takeuchi, A. Takahashi, and N. Motoi Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo Cancer Res 70 2010 9381 9390
-
(2010)
Cancer Res
, vol.70
, pp. 9381-9390
-
-
Takeuchi, S.1
Takahashi, A.2
Motoi, N.3
-
78
-
-
79955047394
-
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
-
S. Minagawa, J. Araya, and T. Numata Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells Am J Physiol Lung Cell Mol Physiol 300 2011 L391 L401
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
-
-
Minagawa, S.1
Araya, J.2
Numata, T.3
-
79
-
-
0030215822
-
P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis
-
K. Kuwano, R. Kunitake, and M. Kawasaki P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis Am J Respir Crit Care Med 154 1996 477 483
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 477-483
-
-
Kuwano, K.1
Kunitake, R.2
Kawasaki, M.3
-
80
-
-
84856706398
-
Idiopathic pulmonary fibrosis: Immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic markers
-
N.J. Lomas, K.L. Watts, K.M. Akram, N.R. Forsyth, and M.A. Spiteri Idiopathic pulmonary fibrosis: immunohistochemical analysis provides fresh insights into lung tissue remodelling with implications for novel prognostic markers Int J Clin Exp Pathol 5 2012 58 71
-
(2012)
Int J Clin Exp Pathol
, vol.5
, pp. 58-71
-
-
Lomas, N.J.1
Watts, K.L.2
Akram, K.M.3
Forsyth, N.R.4
Spiteri, M.A.5
-
81
-
-
33746977705
-
Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis
-
M. Chilosi, A. Zamò, and C. Doglioni Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis Respir Res 7 2006 95
-
(2006)
Respir Res
, vol.7
, pp. 95
-
-
Chilosi, M.1
Zamò, A.2
Doglioni, C.3
-
82
-
-
76749165460
-
Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis
-
T.H. Sisson, M. Mendez, and K. Choi Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis Am J Respir Crit Care Med 181 2010 254 263
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 254-263
-
-
Sisson, T.H.1
Mendez, M.2
Choi, K.3
-
84
-
-
79951542163
-
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2
-
E.T. Domyan, E. Ferretti, K. Throckmorton, Y. Mishina, S.K. Nicolis, and X. Sun Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2 Development 138 2011 971 981
-
(2011)
Development
, vol.138
, pp. 971-981
-
-
Domyan, E.T.1
Ferretti, E.2
Throckmorton, K.3
Mishina, Y.4
Nicolis, S.K.5
Sun, X.6
-
85
-
-
41549108935
-
Idiopathic pulmonary fibrosis: Aberrant recapitulation of developmental programs?
-
M. Selman, A. Pardo, and N. Kaminski Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs? PLoS Med 5 2008 e62
-
(2008)
PLoS Med
, vol.5
, pp. 62
-
-
Selman, M.1
Pardo, A.2
Kaminski, N.3
-
87
-
-
77956288500
-
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
-
W.R. Henderson Jr., E.Y. Chi, and X. Ye Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis Proc Natl Acad Sci U S A 107 2010 14309 14314
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14309-14314
-
-
Henderson, Jr.W.R.1
Chi, E.Y.2
Ye, X.3
-
88
-
-
79958822662
-
Blockade of the Wnt/β-catenin pathway attenuates bleomycin-induced pulmonary fibrosis
-
T.H. Kim, S.H. Kim, and J.Y. Seo Blockade of the Wnt/β-catenin pathway attenuates bleomycin-induced pulmonary fibrosis Tohoku J Exp Med 223 2011 45 54
-
(2011)
Tohoku J Exp Med
, vol.223
, pp. 45-54
-
-
Kim, T.H.1
Kim, S.H.2
Seo, J.Y.3
-
89
-
-
77949881221
-
The senescence-associated secretory phenotype: The dark side of tumor suppression
-
J.P. Coppé, P.Y. Desprez, A. Krtolica, and J. Campisi The senescence-associated secretory phenotype: the dark side of tumor suppression Annu Rev Pathol 5 2010 99 118
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 99-118
-
-
Coppé, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
90
-
-
58849154235
-
Senescence-messaging secretome: SMS-ing cellular stress
-
T. Kuilman, and D.S. Peeper Senescence-messaging secretome: SMS-ing cellular stress Nat Rev Cancer 9 2009 81 94
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 81-94
-
-
Kuilman, T.1
Peeper, D.S.2
-
91
-
-
68249096784
-
Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion
-
F. Rodier, J.P. Coppé, and C.K. Patil Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion Nat Cell Biol 11 2009 973 979
-
(2009)
Nat Cell Biol
, vol.11
, pp. 973-979
-
-
Rodier, F.1
Coppé, J.P.2
Patil, C.K.3
-
92
-
-
84876100085
-
Molecular basis for the tissue specificity of β-catenin oncogenesis
-
A. Sharma, and J.M. Sen Molecular basis for the tissue specificity of β-catenin oncogenesis Oncogene 32 2013 1901 1909
-
(2013)
Oncogene
, vol.32
, pp. 1901-1909
-
-
Sharma, A.1
Sen, J.M.2
-
93
-
-
40749092119
-
Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo
-
M. Xu, Q. Yu, R. Subrahmanyam, M.J. Difilippantonio, T. Ried, and J.M. Sen Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo Mol Cell Biol 28 2008 1713 1723
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1713-1723
-
-
Xu, M.1
Yu, Q.2
Subrahmanyam, R.3
Difilippantonio, M.J.4
Ried, T.5
Sen, J.M.6
-
94
-
-
80052196384
-
Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress
-
H. Tanjore, D.S. Cheng, and A.L. Degryse Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress J Biol Chem 286 2011 30972 30980
-
(2011)
J Biol Chem
, vol.286
, pp. 30972-30980
-
-
Tanjore, H.1
Cheng, D.S.2
Degryse, A.L.3
-
95
-
-
84859740294
-
Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis
-
H. Tanjore, T.S. Blackwell, and W.E. Lawson Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis Am J Physiol Lung Cell Mol Physiol 302 2012 L721 L729
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
-
-
Tanjore, H.1
Blackwell, T.S.2
Lawson, W.E.3
-
96
-
-
17844384822
-
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
-
B.C. Willis, J.M. Liebler, and K. Luby-Phelps Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis Am J Pathol 166 2005 1321 1332
-
(2005)
Am J Pathol
, vol.166
, pp. 1321-1332
-
-
Willis, B.C.1
Liebler, J.M.2
Luby-Phelps, K.3
-
97
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
J.P. Thiery, H. Acloque, and R.Y. Huang Epithelial-mesenchymal transitions in development and disease Cell 139 2009 871 890
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
-
98
-
-
77955497665
-
The role of the miR-200 family in epithelial-mesenchymal transition
-
P.S. Mongroo, and A.K. Rustgi The role of the miR-200 family in epithelial-mesenchymal transition Cancer Biol Ther 10 2010 219 222
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 219-222
-
-
Mongroo, P.S.1
Rustgi, A.K.2
-
99
-
-
84856006423
-
Participation of miR-200 in pulmonary fibrosis
-
S. Yang, S. Banerjee, and A. de Freitas Participation of miR-200 in pulmonary fibrosis Am J Pathol 180 2012 484 493
-
(2012)
Am J Pathol
, vol.180
, pp. 484-493
-
-
Yang, S.1
Banerjee, S.2
De Freitas, A.3
-
100
-
-
0035026949
-
Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expression
-
C. Ramos, M. Montaño, and J. García-Alvarez Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expression Am J Respir Cell Mol Biol 24 2001 591 598
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 591-598
-
-
Ramos, C.1
Montaño, M.2
García-Alvarez, J.3
-
101
-
-
33748685796
-
Fibroblast foci are not discrete sites of lung injury or repair: The fibroblast reticulum
-
C.D. Cool, S.D. Groshong, P.R. Rai, P.M. Henson, J.S. Stewart, and K.K. Brown Fibroblast foci are not discrete sites of lung injury or repair: the fibroblast reticulum Am J Respir Crit Care Med 174 2006 654 658
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 654-658
-
-
Cool, C.D.1
Groshong, S.D.2
Rai, P.R.3
Henson, P.M.4
Stewart, J.S.5
Brown, K.K.6
-
102
-
-
84859015820
-
STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF
-
D.V. Pechkovsky, C.M. Prêle, and J. Wong STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF Am J Pathol 180 2012 1398 1412
-
(2012)
Am J Pathol
, vol.180
, pp. 1398-1412
-
-
Pechkovsky, D.V.1
Prêle, C.M.2
Wong, J.3
-
103
-
-
84865824048
-
Idiopathic pulmonary fibrosis: An altered fibroblast proliferation linked to cancer biology
-
C. Vancheri Idiopathic pulmonary fibrosis: an altered fibroblast proliferation linked to cancer biology Proc Am Thorac Soc 9 2012 153 157
-
(2012)
Proc Am Thorac Soc
, vol.9
, pp. 153-157
-
-
Vancheri, C.1
-
104
-
-
84875985279
-
FoxO3a (forkhead box O3a) deficiency protects idiopathic pulmonary fibrosis (IPF) fibroblasts from type i polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas
-
R.S. Nho, M. Peterson, P. Hergert, and C.A. Henke FoxO3a (forkhead box O3a) deficiency protects idiopathic pulmonary fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas PLoS One 8 2013 e61017
-
(2013)
PLoS One
, vol.8
, pp. 61017
-
-
Nho, R.S.1
Peterson, M.2
Hergert, P.3
Henke, C.A.4
-
105
-
-
84865121019
-
Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction
-
X. Huang, N. Yang, and V.F. Fiore Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction Am J Respir Cell Mol Biol 47 2012 340 348
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, pp. 340-348
-
-
Huang, X.1
Yang, N.2
Fiore, V.F.3
-
106
-
-
84874609382
-
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
-
Y. Zhou, X. Huang, and L. Hecker Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis J Clin Invest 123 2013 1096 1108
-
(2013)
J Clin Invest
, vol.123
, pp. 1096-1108
-
-
Zhou, Y.1
Huang, X.2
Hecker, L.3
-
107
-
-
33845899411
-
Caveolin-1: A critical regulator of lung fibrosis in idiopathic pulmonary fibrosis
-
X.M. Wang, Y. Zhang, and H.P. Kim Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis J Exp Med 203 2006 2895 2906
-
(2006)
J Exp Med
, vol.203
, pp. 2895-2906
-
-
Wang, X.M.1
Zhang, Y.2
Kim, H.P.3
-
108
-
-
77953188523
-
Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis
-
H. Xia, W. Khalil, J. Kahm, J. Jessurun, J. Kleidon, and C.A. Henke Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis Am J Pathol 176 2010 2626 2637
-
(2010)
Am J Pathol
, vol.176
, pp. 2626-2637
-
-
Xia, H.1
Khalil, W.2
Kahm, J.3
Jessurun, J.4
Kleidon, J.5
Henke, C.A.6
-
110
-
-
84879171327
-
Knock down of caveolin-1 affects morphological and functional hallmarks of human endothelial cells
-
L. Madaro, F. Antonangeli, and A. Favia Knock down of caveolin-1 affects morphological and functional hallmarks of human endothelial cells J Cell Biochem 114 2013 1843 1851
-
(2013)
J Cell Biochem
, vol.114
, pp. 1843-1851
-
-
Madaro, L.1
Antonangeli, F.2
Favia, A.3
-
111
-
-
84855893320
-
Caveolin-1, cellular senescence and age-related diseases
-
H. Zou, E. Stoppani, D. Volonte, and F. Galbiati Caveolin-1, cellular senescence and age-related diseases Mech Ageing Dev 132 2011 533 542
-
(2011)
Mech Ageing Dev
, vol.132
, pp. 533-542
-
-
Zou, H.1
Stoppani, E.2
Volonte, D.3
Galbiati, F.4
-
112
-
-
66149127739
-
Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway
-
J.N. Bartholomew, D. Volonte, and F. Galbiati Caveolin-1 regulates the antagonistic pleiotropic properties of cellular senescence through a novel Mdm2/p53-mediated pathway Cancer Res 69 2009 2878 2886
-
(2009)
Cancer Res
, vol.69
, pp. 2878-2886
-
-
Bartholomew, J.N.1
Volonte, D.2
Galbiati, F.3
-
113
-
-
33845345975
-
Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements
-
A. Dasari, J.N. Bartholomew, D. Volonte, and F. Galbiati Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements Cancer Res 66 2006 10805 10814
-
(2006)
Cancer Res
, vol.66
, pp. 10805-10814
-
-
Dasari, A.1
Bartholomew, J.N.2
Volonte, D.3
Galbiati, F.4
-
114
-
-
34548238224
-
Downregulation of caveolin-1 affects bleomycin-induced growth arrest and cellular senescence in A549 cells
-
A. Linge, K. Weinhold, R. Bläsche, M. Kasper, and K. Barth Downregulation of caveolin-1 affects bleomycin-induced growth arrest and cellular senescence in A549 cells Int J Biochem Cell Biol 39 2007 1964 1974
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1964-1974
-
-
Linge, A.1
Weinhold, K.2
Bläsche, R.3
Kasper, M.4
Barth, K.5
-
115
-
-
84863799096
-
Caveolin-1 deficiency protects from pulmonary fibrosis by modulating epithelial cell senescence in mice
-
P. Shivshankar, C. Brampton, S. Miyasato, M. Kasper, V.J. Thannickal, and C.J. Le Saux Caveolin-1 deficiency protects from pulmonary fibrosis by modulating epithelial cell senescence in mice Am J Respir Cell Mol Biol 47 2012 28 36
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, pp. 28-36
-
-
Shivshankar, P.1
Brampton, C.2
Miyasato, S.3
Kasper, M.4
Thannickal, V.J.5
Le Saux, C.J.6
-
116
-
-
0036798845
-
Abnormal re-epithelialization and lung remodeling in idiopathic pulmonary fibrosis: The role of deltaN-p63
-
M. Chilosi, V. Poletti, and B. Murer Abnormal re-epithelialization and lung remodeling in idiopathic pulmonary fibrosis: the role of deltaN-p63 Lab Invest 82 2002 1335 1345
-
(2002)
Lab Invest
, vol.82
, pp. 1335-1345
-
-
Chilosi, M.1
Poletti, V.2
Murer, B.3
-
117
-
-
77957589550
-
Usual interstitial pneumonia
-
S. Zander, H.H. Popper, J. Jagirdar, A.K. Haque, P.T. Cagle, R. Barrios, Springer
-
M. Chilosi, B. Murer, and V. Poletti Usual interstitial pneumonia S. Zander, H.H. Popper, J. Jagirdar, A.K. Haque, P.T. Cagle, R. Barrios, Molecular pathology of lung diseases 2008 Springer 607 615
-
(2008)
Molecular Pathology of Lung Diseases
, pp. 607-615
-
-
Chilosi, M.1
Murer, B.2
Poletti, V.3
-
118
-
-
80054030182
-
Epithelial progenitor cells in lung development, maintenance, repair, and disease
-
J.R. Rock, and B.L. Hogan Epithelial progenitor cells in lung development, maintenance, repair, and disease Annu Rev Cell Dev Biol 27 2011 493 512
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 493-512
-
-
Rock, J.R.1
Hogan, B.L.2
-
119
-
-
0141994029
-
Beta-catenin is required for specification of proximal/distal cell fate during lung morphogenesis
-
M.L. Mucenski, S.E. Wert, and J.M. Nation Beta-catenin is required for specification of proximal/distal cell fate during lung morphogenesis J Biol Chem 278 2003 40231 40238
-
(2003)
J Biol Chem
, vol.278
, pp. 40231-40238
-
-
Mucenski, M.L.1
Wert, S.E.2
Nation, J.M.3
-
120
-
-
20444445954
-
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung
-
W. Shu, S. Guttentag, and Z. Wang Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung Dev Biol 283 2005 226 239
-
(2005)
Dev Biol
, vol.283
, pp. 226-239
-
-
Shu, W.1
Guttentag, S.2
Wang, Z.3
-
121
-
-
0035071913
-
Constitutive p63 expression in airway basal cells: A molecular target in diffuse lung diseases
-
M. Chilosi, and C. Doglioni Constitutive p63 expression in airway basal cells: a molecular target in diffuse lung diseases Sarcoidosis Vasc Diffuse Lung Dis 18 2001 23 26
-
(2001)
Sarcoidosis Vasc Diffuse Lung Dis
, vol.18
, pp. 23-26
-
-
Chilosi, M.1
Doglioni, C.2
-
122
-
-
69149106207
-
Basal cells as stem cells of the mouse trachea and human airway epithelium
-
J.R. Rock, M.W. Onaitis, and E.L. Rawlins Basal cells as stem cells of the mouse trachea and human airway epithelium Proc Natl Acad Sci U S A 106 2009 12771 12775
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12771-12775
-
-
Rock, J.R.1
Onaitis, M.W.2
Rawlins, E.L.3
-
123
-
-
77956538031
-
Airway basal stem cells: A perspective on their roles in epithelial homeostasis and remodeling
-
J.R. Rock, S.H. Randell, and B.L. Hogan Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling Dis Model Mech 3 2010 545 556
-
(2010)
Dis Model Mech
, vol.3
, pp. 545-556
-
-
Rock, J.R.1
Randell, S.H.2
Hogan, B.L.3
-
124
-
-
1542319868
-
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium
-
K.U. Hong, S.D. Reynolds, and S. Watkins Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium Am J Pathol 164 2004 577 588
-
(2004)
Am J Pathol
, vol.164
, pp. 577-588
-
-
Hong, K.U.1
Reynolds, S.D.2
Watkins, S.3
-
125
-
-
84856692365
-
β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial- mesenchymal transition
-
A. Giangreco, L. Lu, and C. Vickers β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition J Pathol 226 2012 575 587
-
(2012)
J Pathol
, vol.226
, pp. 575-587
-
-
Giangreco, A.1
Lu, L.2
Vickers, C.3
-
126
-
-
73349088166
-
TAp63 induces senescence and suppresses tumorigenesis in vivo
-
X. Guo, W.M. Keyes, and C. Papazoglu TAp63 induces senescence and suppresses tumorigenesis in vivo Nat Cell Biol 11 2009 1451 1457
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1451-1457
-
-
Guo, X.1
Keyes, W.M.2
Papazoglu, C.3
-
127
-
-
34247511981
-
P63 Is essential for the proliferative potential of stem cells in stratified epithelia
-
M. Senoo, F. Pinto, C.P. Crum, and F. McKeon p63 Is essential for the proliferative potential of stem cells in stratified epithelia Cell 129 2007 523 536
-
(2007)
Cell
, vol.129
, pp. 523-536
-
-
Senoo, M.1
Pinto, F.2
Crum, C.P.3
McKeon, F.4
-
128
-
-
34347379049
-
P63: Revving up epithelial stem-cell potential
-
C. Blanpain, and E. Fuchs p63: revving up epithelial stem-cell potential Nat Cell Biol 9 2007 731 733
-
(2007)
Nat Cell Biol
, vol.9
, pp. 731-733
-
-
Blanpain, C.1
Fuchs, E.2
-
129
-
-
2942677539
-
Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium
-
Y. Daniely, G. Liao, and D. Dixon Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium Am J Physiol Cell Physiol 287 2004 C171 C181
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Daniely, Y.1
Liao, G.2
Dixon, D.3
-
130
-
-
10744221856
-
Significance of p63 amplification and overexpression in lung cancer development and prognosis
-
P.P. Massion, P.M. Taflan, and S.M. Jamshedur Rahman Significance of p63 amplification and overexpression in lung cancer development and prognosis Cancer Res 63 2003 7113 7121
-
(2003)
Cancer Res
, vol.63
, pp. 7113-7121
-
-
Massion, P.P.1
Taflan, P.M.2
Jamshedur Rahman, S.M.3
-
131
-
-
79551607574
-
Δnp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis
-
W.M. Keyes, M. Pecoraro, and V. Aranda ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis Cell Stem Cell 8 2011 164 176
-
(2011)
Cell Stem Cell
, vol.8
, pp. 164-176
-
-
Keyes, W.M.1
Pecoraro, M.2
Aranda, V.3
-
132
-
-
32244434160
-
P63: A new link between senescence and aging
-
W.M. Keyes, and A.A. Mills p63: a new link between senescence and aging Cell Cycle 5 2006 260 265
-
(2006)
Cell Cycle
, vol.5
, pp. 260-265
-
-
Keyes, W.M.1
Mills, A.A.2
-
133
-
-
24344447780
-
P63 Deficiency activates a program of cellular senescence and leads to accelerated aging
-
W.M. Keyes, Y. Wu, H. Vogel, X. Guo, S.W. Lowe, and A.A. Mills p63 Deficiency activates a program of cellular senescence and leads to accelerated aging Genes Dev 19 2005 1986 1999
-
(2005)
Genes Dev
, vol.19
, pp. 1986-1999
-
-
Keyes, W.M.1
Wu, Y.2
Vogel, H.3
Guo, X.4
Lowe, S.W.5
Mills, A.A.6
-
135
-
-
84875456720
-
A localized Wnt signal orients asymmetric stem cell division in vitro
-
S.J. Habib, B.C. Chen, and F.C. Tsai A localized Wnt signal orients asymmetric stem cell division in vitro Science 339 2013 1445 1448
-
(2013)
Science
, vol.339
, pp. 1445-1448
-
-
Habib, S.J.1
Chen, B.C.2
Tsai, F.C.3
-
136
-
-
80054793413
-
Wnt/Myc interactions in intestinal cancer: Partners in crime
-
K. Myant, and O.J. Sansom Wnt/Myc interactions in intestinal cancer: partners in crime Exp Cell Res 317 2011 2725 2731
-
(2011)
Exp Cell Res
, vol.317
, pp. 2725-2731
-
-
Myant, K.1
Sansom, O.J.2
-
138
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
T.C. He, C.A.B. Sparks, and C.H. Rago Identification of c-MYC as a target of the APC pathway Science 281 1998 1509 1512
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, C.A.B.2
Rago, C.H.3
-
139
-
-
0029840701
-
C-Myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways
-
G. Packham, C.W. Porter, and J.L. Cleveland c-Myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways Oncogene 13 1996 461 469
-
(1996)
Oncogene
, vol.13
, pp. 461-469
-
-
Packham, G.1
Porter, C.W.2
Cleveland, J.L.3
-
140
-
-
2642510818
-
Cancer cell biology: Myc wins the competition
-
T.D. Donaldson, and R.J. Duronio Cancer cell biology: Myc wins the competition Curr Biol 14 2004 R425 R427
-
(2004)
Curr Biol
, vol.14
-
-
Donaldson, T.D.1
Duronio, R.J.2
-
141
-
-
1842665674
-
DMyc transforms cells into super-competitors
-
E. Moreno, and K. Basler dMyc transforms cells into super-competitors Cell 117 2004 117 129
-
(2004)
Cell
, vol.117
, pp. 117-129
-
-
Moreno, E.1
Basler, K.2
-
142
-
-
1842816486
-
Drosophila myc regulates organ size by inducing cell competition
-
C. de la Cova, M. Abril, P. Bellosta, P. Gallant, and L.A. Johnston Drosophila myc regulates organ size by inducing cell competition Cell 117 2004 107 116
-
(2004)
Cell
, vol.117
, pp. 107-116
-
-
De La Cova, C.1
Abril, M.2
Bellosta, P.3
Gallant, P.4
Johnston, L.A.5
-
143
-
-
84875729306
-
Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation
-
G. Wettstein, P.S. Bellaye, and M. Kolb Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation FASEB J 27 2013 1549 1560
-
(2013)
FASEB J
, vol.27
, pp. 1549-1560
-
-
Wettstein, G.1
Bellaye, P.S.2
Kolb, M.3
-
144
-
-
0034512869
-
The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis
-
S.J. Charette, and J. Landry The interaction of HSP27 with Daxx identifies a potential regulatory role of HSP27 in Fas-induced apoptosis Ann N Y Acad Sci 926 2000 126 131
-
(2000)
Ann N y Acad Sci
, vol.926
, pp. 126-131
-
-
Charette, S.J.1
Landry, J.2
-
145
-
-
0034282104
-
Hsp27 negatively regulates cell death by interacting with cytochrome c
-
J.M. Bruey, C. Ducasse, and P. Bonniaud Hsp27 negatively regulates cell death by interacting with cytochrome c Nat Cell Biol 2: 2000 645 652
-
(2000)
Nat Cell Biol
, vol.2
, pp. 645-652
-
-
Bruey, J.M.1
Ducasse, C.2
Bonniaud, P.3
-
146
-
-
70349507340
-
The shock of aging: Molecular chaperones and the heat shock response in longevity and aging: A mini-review
-
S.K. Calderwood, A. Murshid, and T. Prince The shock of aging: molecular chaperones and the heat shock response in longevity and aging: a mini-review Gerontology 55 2009 550 558
-
(2009)
Gerontology
, vol.55
, pp. 550-558
-
-
Calderwood, S.K.1
Murshid, A.2
Prince, T.3
-
148
-
-
37549025455
-
Hsp27 modulates p53 signaling and suppresses cellular senescence
-
C. O'Callaghan-Sunol, V.L. Gabai, and M.Y. Sherman Hsp27 modulates p53 signaling and suppresses cellular senescence Cancer Res 67 2007 11779 11788
-
(2007)
Cancer Res
, vol.67
, pp. 11779-11788
-
-
O'Callaghan-Sunol, C.1
Gabai, V.L.2
Sherman, M.Y.3
-
149
-
-
77956518441
-
Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: Implications for age-related macular degeneration
-
M. Pons, S.W. Cousins, K.G. Csaky, G. Striker, and M.E. Marin-Castaño Cigarette smoke-related hydroquinone induces filamentous actin reorganization and heat shock protein 27 phosphorylation through p38 and extracellular signal-regulated kinase 1/2 in retinal pigment epithelium: implications for age-related macular degeneration Am J Pathol 177 2010 1198 1213
-
(2010)
Am J Pathol
, vol.177
, pp. 1198-1213
-
-
Pons, M.1
Cousins, S.W.2
Csaky, K.G.3
Striker, G.4
Marin-Castaño, M.E.5
-
150
-
-
0033516660
-
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation
-
T. Rogalla, M. Ehrnsperger, and X. Preville Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation J Biol Chem 274 1999 18947 18956
-
(1999)
J Biol Chem
, vol.274
, pp. 18947-18956
-
-
Rogalla, T.1
Ehrnsperger, M.2
Preville, X.3
-
151
-
-
0028176312
-
The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin
-
C.M. Niessen, F. Hogervorst, and L.H. Jaspars The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin Exp Cell Res 211 1994 360 367
-
(1994)
Exp Cell Res
, vol.211
, pp. 360-367
-
-
Niessen, C.M.1
Hogervorst, F.2
Jaspars, L.H.3
-
152
-
-
3042749811
-
Epithelial cell motility on laminin-5: Regulation by matrix assembly, proteolysis, integrins and erbB receptors
-
E. Hintermann, and V. Quaranta Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors Matrix Biol 23 2004 75 85
-
(2004)
Matrix Biol
, vol.23
, pp. 75-85
-
-
Hintermann, E.1
Quaranta, V.2
-
153
-
-
0036787804
-
Distribution of laminin 5, integrin receptors, and branching morphogenesis during human fetal lung development
-
C. Coraux, G. Meneguzzi, P. Rousselle, E. Puchelle, and D. Gaillard Distribution of laminin 5, integrin receptors, and branching morphogenesis during human fetal lung development Dev Dyn 225 2002 176 185
-
(2002)
Dev Dyn
, vol.225
, pp. 176-185
-
-
Coraux, C.1
Meneguzzi, G.2
Rousselle, P.3
Puchelle, E.4
Gaillard, D.5
-
154
-
-
0035890760
-
Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin
-
F. Hlubek, A. Jung, N. Kotzor, T. Kirchner, and T. Brabletz Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin Cancer Res 61 2001 8089 8093
-
(2001)
Cancer Res
, vol.61
, pp. 8089-8093
-
-
Hlubek, F.1
Jung, A.2
Kotzor, N.3
Kirchner, T.4
Brabletz, T.5
-
155
-
-
0028173385
-
The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers
-
C. Pyke, J. Romer, and P. Kallunki The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers Am J Pathol 145 1994 782 791
-
(1994)
Am J Pathol
, vol.145
, pp. 782-791
-
-
Pyke, C.1
Romer, J.2
Kallunki, P.3
-
156
-
-
33744732501
-
A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence
-
E. Natarajan, J.D. Omobono II, and Z. Guo A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence Am J Pathol 168 2006 1821 1837
-
(2006)
Am J Pathol
, vol.168
, pp. 1821-1837
-
-
Natarajan, E.1
Omobono, I.I.J.D.2
Guo, Z.3
-
157
-
-
79955146233
-
A common MUC5B promoter polymorphism and pulmonary fibrosis
-
M.A. Seibold, A.L. Wise, and M.C. Speer A common MUC5B promoter polymorphism and pulmonary fibrosis N Engl J Med 364 2011 1503 1512
-
(2011)
N Engl J Med
, vol.364
, pp. 1503-1512
-
-
Seibold, M.A.1
Wise, A.L.2
Speer, M.C.3
-
158
-
-
79960612606
-
Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis
-
L. Plantier, B. Crestani, and S.E. Wert Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis Thorax 66 2011 651 657
-
(2011)
Thorax
, vol.66
, pp. 651-657
-
-
Plantier, L.1
Crestani, B.2
Wert, S.E.3
-
159
-
-
84875176842
-
The idiopathic pulmonary fibrosis honeycomb cyst contains a mucociliary pseudostratified epithelium
-
M.A. Seibold, R.W. Smith, and C. Urbanek The idiopathic pulmonary fibrosis honeycomb cyst contains a mucociliary pseudostratified epithelium PLoS One 8 2013 e58658
-
(2013)
PLoS One
, vol.8
, pp. 58658
-
-
Seibold, M.A.1
Smith, R.W.2
Urbanek, C.3
-
160
-
-
37549060070
-
Accelerated variant of idiopathic pulmonary fibrosis: Clinical behavior and gene expression pattern
-
M. Selman, G. Carrillo, and A. Estrada Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern PLoS One 2 2007 e482
-
(2007)
PLoS One
, vol.2
, pp. 482
-
-
Selman, M.1
Carrillo, G.2
Estrada, A.3
-
161
-
-
0242467564
-
Acute exacerbation of idiopathic pulmonary fibrosis: Report of a series
-
V. Ambrosini, A. Cancellieri, and M. Chilosi Acute exacerbation of idiopathic pulmonary fibrosis: report of a series Eur Respir J 22 2003 821 826
-
(2003)
Eur Respir J
, vol.22
, pp. 821-826
-
-
Ambrosini, V.1
Cancellieri, A.2
Chilosi, M.3
-
162
-
-
34547132777
-
Immunosenescence: Deficits in adaptive immunity in the elderly
-
F.T. Hakim, and R.E. Gress Immunosenescence: deficits in adaptive immunity in the elderly Tissue Antigens 70 2007 179 189
-
(2007)
Tissue Antigens
, vol.70
, pp. 179-189
-
-
Hakim, F.T.1
Gress, R.E.2
-
163
-
-
84864017351
-
Role of CD8 T cell replicative senescence in human aging and in HIV-mediated immunosenescence
-
J.N. Dock, and R.B. Effros Role of CD8 T cell replicative senescence in human aging and in HIV-mediated immunosenescence Aging Dis 2 2011 382 397
-
(2011)
Aging Dis
, vol.2
, pp. 382-397
-
-
Dock, J.N.1
Effros, R.B.2
-
164
-
-
39649085837
-
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
-
C. Franceschi Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr Rev 65 2007 S173 S176
-
(2007)
Nutr Rev
, vol.65
-
-
Franceschi, C.1
-
165
-
-
84880998606
-
Aberrant innate immune sensing leads to the rapid progression of idiopathic pulmonary fibrosis
-
C.M. Hogaboam, G. Trujillo, and F.J. Martinez Aberrant innate immune sensing leads to the rapid progression of idiopathic pulmonary fibrosis Fibrogenesis Tissue Rep 5 2012 S3
-
(2012)
Fibrogenesis Tissue Rep
, vol.5
, pp. 3
-
-
Hogaboam, C.M.1
Trujillo, G.2
Martinez, F.J.3
-
166
-
-
78349285513
-
TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis
-
G. Trujillo, A. Meneghin, and K.R. Flaherty TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis Sci Transl Med 2 2010 57ra82
-
(2010)
Sci Transl Med
, vol.2
-
-
Trujillo, G.1
Meneghin, A.2
Flaherty, K.R.3
-
167
-
-
77952489797
-
CD28 down-regulation on circulating CD4 T-cells is associated with poor prognoses of patients with idiopathic pulmonary fibrosis
-
S.R. Gilani, L.J. Vuga, and K.O. Lindell CD28 down-regulation on circulating CD4 T-cells is associated with poor prognoses of patients with idiopathic pulmonary fibrosis PLoS One 5 2010 e8959
-
(2010)
PLoS One
, vol.5
, pp. 8959
-
-
Gilani, S.R.1
Vuga, L.J.2
Lindell, K.O.3
-
168
-
-
84875075526
-
Toll like receptor signaling in "inflammaging": MicroRNA as new players
-
F. Olivieri, M.R. Rippo, and F. Prattichizzo Toll like receptor signaling in "inflammaging": microRNA as new players Immun Ageing 10 2013 11
-
(2013)
Immun Ageing
, vol.10
, pp. 11
-
-
Olivieri, F.1
Rippo, M.R.2
Prattichizzo, F.3
-
169
-
-
84858019892
-
T-cell biology in aging, with a focus on lung disease
-
N. Lee, M.S. Shin, and I. Kang T-cell biology in aging, with a focus on lung disease J Gerontol A Biol Sci Med Sci 67 2012 254 263
-
(2012)
J Gerontol A Biol Sci Med Sci
, vol.67
, pp. 254-263
-
-
Lee, N.1
Shin, M.S.2
Kang, I.3
-
170
-
-
67649407892
-
CD28(-) T cells: Their role in the age-associated decline of immune function
-
N.P. Weng, A.N. Akbar, and J. Goronzy CD28(-) T cells: their role in the age-associated decline of immune function Trends Immunol 30 2009 306 312
-
(2009)
Trends Immunol
, vol.30
, pp. 306-312
-
-
Weng, N.P.1
Akbar, A.N.2
Goronzy, J.3
-
171
-
-
34848884629
-
Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis
-
C.A. Feghali-Bostwick, C.G. Tsai, and V.G. Valentine Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis J Immunol 179 2007 2592 2599
-
(2007)
J Immunol
, vol.179
, pp. 2592-2599
-
-
Feghali-Bostwick, C.A.1
Tsai, C.G.2
Valentine, V.G.3
-
172
-
-
47949115533
-
Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis
-
K. Kurosu, Y. Takiguchi, and O. Okada Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis J Immunol 181 2008 756 767
-
(2008)
J Immunol
, vol.181
, pp. 756-767
-
-
Kurosu, K.1
Takiguchi, Y.2
Okada, O.3
-
173
-
-
34548693221
-
Autoantibody to alanyl-tRNA synthetase in patients with idiopathic pulmonary fibrosis
-
T. Takahashi, I. Wada, Y. Ohtsuka, M. Munakata, Y. Homma, and Y. Kuroki Autoantibody to alanyl-tRNA synthetase in patients with idiopathic pulmonary fibrosis Respirology 12 2007 642 653
-
(2007)
Respirology
, vol.12
, pp. 642-653
-
-
Takahashi, T.1
Wada, I.2
Ohtsuka, Y.3
Munakata, M.4
Homma, Y.5
Kuroki, Y.6
-
174
-
-
84875864680
-
Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses
-
R.A. Kahloon, J. Xue, and A. Bhargava Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses Am J Respir Crit Care Med 187 2013 768 775
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 768-775
-
-
Kahloon, R.A.1
Xue, J.2
Bhargava, A.3
-
175
-
-
33646481327
-
Cutting edge: Nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis
-
J. Marchal-Sommé, Y. Uzunhan, and S. Marchand-Adam Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis J Immunol 176 2006 5735 5739
-
(2006)
J Immunol
, vol.176
, pp. 5735-5739
-
-
Marchal-Sommé, J.1
Uzunhan, Y.2
Marchand-Adam, S.3
-
176
-
-
84864776533
-
Pathogenesis of chronic obstructive pulmonary disease
-
R.M. Tuder, and I. Petrache Pathogenesis of chronic obstructive pulmonary disease J Clin Invest 122 2012 2749 2755
-
(2012)
J Clin Invest
, vol.122
, pp. 2749-2755
-
-
Tuder, R.M.1
Petrache, I.2
-
177
-
-
73149099640
-
Mechanisms of lung development: Contribution to adult lung disease and relevance to chronic obstructive pulmonary disease
-
W. Shi, F. Chen, and W.V. Cardoso Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease Proc Am Thorac Soc 6 2009 558 563
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 558-563
-
-
Shi, W.1
Chen, F.2
Cardoso, W.V.3
-
178
-
-
73449092528
-
Early life origins of chronic obstructive pulmonary disease
-
C. Svanes, J. Sunyer, and E. Plana Early life origins of chronic obstructive pulmonary disease Thorax 65 2010 14 20
-
(2010)
Thorax
, vol.65
, pp. 14-20
-
-
Svanes, C.1
Sunyer, J.2
Plana, E.3
-
179
-
-
84864604353
-
Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease
-
G.K. Acquaah-Mensah, D. Malhotra, M. Vulimiri, J.E. McDermott, and S. Biswal Suppressed expression of T-box transcription factors is involved in senescence in chronic obstructive pulmonary disease PLoS Comput Biol 8 2012 e1002597
-
(2012)
PLoS Comput Biol
, vol.8
, pp. 1002597
-
-
Acquaah-Mensah, G.K.1
Malhotra, D.2
Vulimiri, M.3
McDermott, J.E.4
Biswal, S.5
-
180
-
-
34547628244
-
Genetic predisposition to accelerated decline of lung function in COPD
-
N.A. Molfino Genetic predisposition to accelerated decline of lung function in COPD Int J Chron Obstruct Pulmon Dis 2 2007 117 119
-
(2007)
Int J Chron Obstruct Pulmon Dis
, vol.2
, pp. 117-119
-
-
Molfino, N.A.1
-
181
-
-
58249099942
-
COPD as a disease of accelerated lung aging
-
K. Ito, and P.J. Barnes COPD as a disease of accelerated lung aging Chest 135 2009 173 180
-
(2009)
Chest
, vol.135
, pp. 173-180
-
-
Ito, K.1
Barnes, P.J.2
-
182
-
-
71549166705
-
Telomere length and chronic obstructive pulmonary disease: Evidence of accelerated aging
-
T.S. Mui, J.M. Man, and J.E. McElhaney Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging J Am Geriatr Soc 57 2009 2372 2374
-
(2009)
J Am Geriatr Soc
, vol.57
, pp. 2372-2374
-
-
Mui, T.S.1
Man, J.M.2
McElhaney, J.E.3
-
183
-
-
58249084014
-
Telomere shortening in chronic obstructive pulmonary disease
-
J.M. Houben, E.M. Mercken, and H.B. Ketelslegers Telomere shortening in chronic obstructive pulmonary disease Respir Med 103 2009 230 236
-
(2009)
Respir Med
, vol.103
, pp. 230-236
-
-
Houben, J.M.1
Mercken, E.M.2
Ketelslegers, H.B.3
-
184
-
-
65249172518
-
Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease
-
L. Savale, A. Chaouat, and S. Bastuji-Garin Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 179 2009 566 571
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 566-571
-
-
Savale, L.1
Chaouat, A.2
Bastuji-Garin, S.3
-
185
-
-
78651431729
-
Systemic manifestations of COPD
-
Y. Nussbaumer-Ochsner, and K.F. Rabe Systemic manifestations of COPD Chest 139 2011 165 173
-
(2011)
Chest
, vol.139
, pp. 165-173
-
-
Nussbaumer-Ochsner, Y.1
Rabe, K.F.2
-
186
-
-
77955716077
-
Aging, telomeres and heart failure
-
L.S. Wong, P. van der Harst, R.A. de Boer, J. Huzen, W.H. van Gilst, and D.J. van Veldhuisen Aging, telomeres and heart failure Heart Fail Rev 15 2010 479 486
-
(2010)
Heart Fail Rev
, vol.15
, pp. 479-486
-
-
Wong, L.S.1
Van Der Harst, P.2
De Boer, R.A.3
Huzen, J.4
Van Gilst, W.H.5
Van Veldhuisen, D.J.6
-
187
-
-
84875847989
-
Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease
-
L.E. Vanfleteren, M.A. Spruit, and M. Groenen Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease Am J Respir Crit Care Med 187 2013 728 735
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 728-735
-
-
Vanfleteren, L.E.1
Spruit, M.A.2
Groenen, M.3
-
188
-
-
67649224269
-
Progression of chronic obstructive pulmonary disease: Impact of inflammation, comorbidities and therapeutic intervention
-
R.A. Stockley Progression of chronic obstructive pulmonary disease: impact of inflammation, comorbidities and therapeutic intervention Curr Med Res Opin 25 2009 1235 1245
-
(2009)
Curr Med Res Opin
, vol.25
, pp. 1235-1245
-
-
Stockley, R.A.1
-
189
-
-
33747876876
-
Telomere shortening and mood disorders: Preliminary support for a chronic stress model of accelerated aging
-
N.M. Simon, J.W. Smoller, and K.L. McNamara Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging Biol Psychiatry 60 2006 432 435
-
(2006)
Biol Psychiatry
, vol.60
, pp. 432-435
-
-
Simon, N.M.1
Smoller, J.W.2
McNamara, K.L.3
-
190
-
-
80054715764
-
Telomere length is a determinant of emphysema susceptibility
-
J.K. Alder, N. Guo, and F. Kembou Telomere length is a determinant of emphysema susceptibility Am J Respir Crit Care Med 184 2011 904 912
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 904-912
-
-
Alder, J.K.1
Guo, N.2
Kembou, F.3
-
191
-
-
84866145918
-
The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD)
-
J. Lee, A.J. Sandford, and J.E. Connett The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD) PLoS One 7 2012 e35567
-
(2012)
PLoS One
, vol.7
, pp. 35567
-
-
Lee, J.1
Sandford, A.J.2
Connett, J.E.3
-
193
-
-
33645781050
-
Lung fibroblasts from patients with emphysema show markers of senescence in vitro
-
K.C. Müller, L. Welker, and K. Paasch Lung fibroblasts from patients with emphysema show markers of senescence in vitro Respir Res 7 2006 32
-
(2006)
Respir Res
, vol.7
, pp. 32
-
-
Müller, K.C.1
Welker, L.2
Paasch, K.3
-
194
-
-
48249116344
-
Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms
-
S. Togo, O. Holz, and X. Liu Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms Am J Respir Crit Care Med 178 2008 248 260
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 248-260
-
-
Togo, S.1
Holz, O.2
Liu, X.3
-
195
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Y. Kasahara, R.M. Tuder, and L. Taraseviciene-Stewart Inhibition of VEGF receptors causes lung cell apoptosis and emphysema J Clin Invest 106 2000 1311 1319
-
(2000)
J Clin Invest
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
-
196
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Y. Kasahara, R.M. Tuder, C.D. Cool, D.A. Lynch, S.C. Flores, and N.F. Voelkel Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema Am J Respir Crit Care Med 163 2001 737 744
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 737-744
-
-
Kasahara, Y.1
Tuder, R.M.2
Cool, C.D.3
Lynch, D.A.4
Flores, S.C.5
Voelkel, N.F.6
-
198
-
-
0037823489
-
Different proliferative capacity of lung fibroblasts obtained from control subjects and patients with emphysema
-
J.A. Noordhoek, D.S. Postma, and L.L. Chong Different proliferative capacity of lung fibroblasts obtained from control subjects and patients with emphysema Exp Lung Res 29 2003 291 302
-
(2003)
Exp Lung Res
, vol.29
, pp. 291-302
-
-
Noordhoek, J.A.1
Postma, D.S.2
Chong, L.L.3
-
199
-
-
84857138582
-
59 Endothelial colony forming cells (ECFC) are senescent and dysfunctional in COPD due to reduced sirtuin-1 levels
-
K. Paschalaki, R.D. Starke, N. Mercado, D.O. Haskard, P.J. Barnes, and A.M. Randi 59 Endothelial colony forming cells (ECFC) are senescent and dysfunctional in COPD due to reduced sirtuin-1 levels Heart 97 2011 e7
-
(2011)
Heart
, vol.97
, pp. 7
-
-
Paschalaki, K.1
Starke, R.D.2
Mercado, N.3
Haskard, D.O.4
Barnes, P.J.5
Randi, A.M.6
-
200
-
-
57649221004
-
Targeted induction of lung endothelial cell apoptosis causes emphysemalike changes in the mouse
-
R.J. Giordano, J. Lahdenranta, and L. Zhen Targeted induction of lung endothelial cell apoptosis causes emphysemalike changes in the mouse J Biol Chem 283 2008 29447 29460
-
(2008)
J Biol Chem
, vol.283
, pp. 29447-29460
-
-
Giordano, R.J.1
Lahdenranta, J.2
Zhen, L.3
-
201
-
-
60549097786
-
Smad gene expression in pulmonary fibroblasts: Indications for defective ECM repair in COPD
-
A. Zandvoort, D.S. Postma, M.R. Jonker, J.A. Noordhoek, J.T. Vos, and W. Timens Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD Respir Res 9 2008 83
-
(2008)
Respir Res
, vol.9
, pp. 83
-
-
Zandvoort, A.1
Postma, D.S.2
Jonker, M.R.3
Noordhoek, J.A.4
Vos, J.T.5
Timens, W.6
-
202
-
-
77956672918
-
Altered fibroblast proteoglycan production in COPD
-
O. Hallgren, K. Nihlberg, and M. Dahlbäck Altered fibroblast proteoglycan production in COPD Respir Res 11 2010 55
-
(2010)
Respir Res
, vol.11
, pp. 55
-
-
Hallgren, O.1
Nihlberg, K.2
Dahlbäck, M.3
-
203
-
-
79954527594
-
Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD
-
R. Wang, J. Ahmed, and G. Wang Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD PLoS One 6 2011 e14793
-
(2011)
PLoS One
, vol.6
, pp. 14793
-
-
Wang, R.1
Ahmed, J.2
Wang, G.3
-
204
-
-
79952715657
-
Activation of the WNT/β-catenin pathway attenuates experimental emphysema
-
N. Kneidinger, A.Ö. Yildirim, and J. Callegari Activation of the WNT/β-catenin pathway attenuates experimental emphysema Am J Respir Crit Care Med 183 2011 723 733
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 723-733
-
-
Kneidinger, N.1
Yildirim, A.Ö.2
Callegari, J.3
-
206
-
-
84885938266
-
Decreased serum transforming growth factor-β1 concentration with aging is associated with the severity of emphysema in chronic obstructive pulmonary disease
-
K. Kamio, T. Ishii, and T. Motegi Decreased serum transforming growth factor-β1 concentration with aging is associated with the severity of emphysema in chronic obstructive pulmonary disease Geriatr Gerontol Int 2013
-
(2013)
Geriatr Gerontol Int
-
-
Kamio, K.1
Ishii, T.2
Motegi, T.3
-
207
-
-
0035891566
-
Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema
-
S. Kononov, K. Brewer, and H. Sakai Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema Am J Respir Crit Care Med 164 2001 1920 1926
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1920-1926
-
-
Kononov, S.1
Brewer, K.2
Sakai, H.3
-
208
-
-
63249129198
-
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease
-
A.E. Tilley, B.G. Harvey, and A. Heguy Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease Am J Respir Crit Care Med 179 2009 457 466
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 457-466
-
-
Tilley, A.E.1
Harvey, B.G.2
Heguy, A.3
-
209
-
-
59649100796
-
Wnt signaling controls the fate of mesenchymal stem cells
-
L. Ling, V. Nurcombe, and S.M. Cool Wnt signaling controls the fate of mesenchymal stem cells Gene 433 2009 1 7
-
(2009)
Gene
, vol.433
, pp. 1-7
-
-
Ling, L.1
Nurcombe, V.2
Cool, S.M.3
-
211
-
-
43049144313
-
Wnt signaling and stem cell control
-
R. Nusse Wnt signaling and stem cell control Cell Res 18 2008 523 527
-
(2008)
Cell Res
, vol.18
, pp. 523-527
-
-
Nusse, R.1
-
212
-
-
70450245198
-
Roles of Wnt/beta-catenin signaling in epithelial differentiation of mesenchymal stem cells
-
Y. Wang, Z. Sun, X. Qiu, Y. Li, J. Qin, and X. Han Roles of Wnt/beta-catenin signaling in epithelial differentiation of mesenchymal stem cells Biochem Biophys Res Commun 390 2009 1309 1314
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 1309-1314
-
-
Wang, Y.1
Sun, Z.2
Qiu, X.3
Li, Y.4
Qin, J.5
Han, X.6
-
213
-
-
34547908461
-
Augmented Wnt signaling in a mammalian model of accelerated aging
-
H. Liu, M.M. Fergusson, and R.M. Castilho Augmented Wnt signaling in a mammalian model of accelerated aging Science 317 2007 803 806
-
(2007)
Science
, vol.317
, pp. 803-806
-
-
Liu, H.1
Fergusson, M.M.2
Castilho, R.M.3
-
214
-
-
42049090788
-
Gone with the Wnt/Notch: Stem cells in laminopathies, progeria, and aging
-
E. Meshorer, and Y. Gruenbaum Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging J Cell Biol 181 2008 9 13
-
(2008)
J Cell Biol
, vol.181
, pp. 9-13
-
-
Meshorer, E.1
Gruenbaum, Y.2
-
215
-
-
77956636550
-
Caveolin-1, cellular senescence and pulmonary emphysema
-
D. Volonte, and F. Galbiati Caveolin-1, cellular senescence and pulmonary emphysema Aging (Albany NY) 1 2009 831 835
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 831-835
-
-
Volonte, D.1
Galbiati, F.2
-
216
-
-
65549125935
-
Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway
-
D. Volonte, B. Kahkonen, S. Shapiro, Y. Di, and F. Galbiati Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway J Biol Chem 284 2009 5462 5466
-
(2009)
J Biol Chem
, vol.284
, pp. 5462-5466
-
-
Volonte, D.1
Kahkonen, B.2
Shapiro, S.3
Di, Y.4
Galbiati, F.5
-
217
-
-
0036323674
-
Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
-
D. Volonte, K. Zhang, M.P. Lisanti, and F. Galbiati Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts Mol Biol Cell 13 2002 2502 2517
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2502-2517
-
-
Volonte, D.1
Zhang, K.2
Lisanti, M.P.3
Galbiati, F.4
-
218
-
-
66149093072
-
The pathology of chronic obstructive pulmonary disease
-
J.C. Hogg, and W. Timens The pathology of chronic obstructive pulmonary disease Annu Rev Pathol 4 2009 435 459
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 435-459
-
-
Hogg, J.C.1
Timens, W.2
-
219
-
-
33751207741
-
Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?
-
L. Taraseviciene-Stewart, I.S. Douglas, and P.S. Nana-Sinkam Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease? Proc Am Thorac Soc 3 2006 687 690
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 687-690
-
-
Taraseviciene-Stewart, L.1
Douglas, I.S.2
Nana-Sinkam, P.S.3
-
220
-
-
42949090409
-
Phenotypic characterisation of T-lymphocytes in COPD: Abnormal CD4+ CD25+ regulatory T-lymphocyte response to tobacco smoking
-
B. Barceló, J. Pons, J.M. Ferrer, J. Sauleda, A. Fuster, and A.G. Agustí Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4+ CD25+ regulatory T-lymphocyte response to tobacco smoking Eur Respir J 31 2008 555 562
-
(2008)
Eur Respir J
, vol.31
, pp. 555-562
-
-
Barceló, B.1
Pons, J.2
Ferrer, J.M.3
Sauleda, J.4
Fuster, A.5
Agustí, A.G.6
-
221
-
-
42949098935
-
To reg or not to reg: That is the question in COPD
-
S. Baraldo, and M. Saetta To reg or not to reg: that is the question in COPD Eur Respir J 31 2008 486 488
-
(2008)
Eur Respir J
, vol.31
, pp. 486-488
-
-
Baraldo, S.1
Saetta, M.2
-
222
-
-
77954722942
-
Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice
-
G.T. Motz, B.L. Eppert, S.C. Wesselkamper, J.L. Flury, and M.T. Borchers Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice Am J Respir Crit Care Med 181 2010 1223 1233
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 1223-1233
-
-
Motz, G.T.1
Eppert, B.L.2
Wesselkamper, S.C.3
Flury, J.L.4
Borchers, M.T.5
-
223
-
-
66649127821
-
Immunologic aspects of chronic obstructive pulmonary disease
-
M.G. Cosio, M. Saetta, and A. Agusti Immunologic aspects of chronic obstructive pulmonary disease N Engl J Med 360 2009 2445 2454
-
(2009)
N Engl J Med
, vol.360
, pp. 2445-2454
-
-
Cosio, M.G.1
Saetta, M.2
Agusti, A.3
-
224
-
-
84871916713
-
Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease
-
S. Fujii, H. Hara, and J. Araya Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease Oncoimmunology 1 2012 630 641
-
(2012)
Oncoimmunology
, vol.1
, pp. 630-641
-
-
Fujii, S.1
Hara, H.2
Araya, J.3
-
225
-
-
79958120387
-
Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury
-
F. Zhou, S. Onizawa, A. Nagai, and K. Aoshiba Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury Respir Res 12 2011 78
-
(2011)
Respir Res
, vol.12
, pp. 78
-
-
Zhou, F.1
Onizawa, S.2
Nagai, A.3
Aoshiba, K.4
-
226
-
-
13544249606
-
Human mesenchymal stem cells modulate allogeneic immune cell responses
-
S. Aggarwal, and M.F. Pittenger Human mesenchymal stem cells modulate allogeneic immune cell responses Blood 105 2005 1815 1822
-
(2005)
Blood
, vol.105
, pp. 1815-1822
-
-
Aggarwal, S.1
Pittenger, M.F.2
-
227
-
-
33745700343
-
Regenerative and immunomodulatory potential of mesenchymal stem cells
-
M. Krampera, A. Pasini, G. Pizzolo, L. Cosmi, S. Romagnani, and F. Annunziato Regenerative and immunomodulatory potential of mesenchymal stem cells Curr Opin Pharmacol 6 2006 435 441
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 435-441
-
-
Krampera, M.1
Pasini, A.2
Pizzolo, G.3
Cosmi, L.4
Romagnani, S.5
Annunziato, F.6
-
228
-
-
50249158511
-
Mesenchymal stem cells in health and disease
-
A. Uccelli, L. Moretta, and V. Pistoia Mesenchymal stem cells in health and disease Nat Rev Immunol 8 2008 726 736
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 726-736
-
-
Uccelli, A.1
Moretta, L.2
Pistoia, V.3
-
229
-
-
36249009667
-
Immune regulation by mesenchymal stem cells derived from adult spleen and thymus
-
M. Krampera, S. Sartoris, and F. Liotta Immune regulation by mesenchymal stem cells derived from adult spleen and thymus Stem Cells Dev 16 2007 797 810
-
(2007)
Stem Cells Dev
, vol.16
, pp. 797-810
-
-
Krampera, M.1
Sartoris, S.2
Liotta, F.3
-
230
-
-
34548442823
-
Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation
-
K.A. Keyser, K.E. Beagles, and H.P. Kiem Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation Cell Transplant 16 2007 555 562
-
(2007)
Cell Transplant
, vol.16
, pp. 555-562
-
-
Keyser, K.A.1
Beagles, K.E.2
Kiem, H.P.3
-
231
-
-
84860437339
-
Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow
-
M. Ricciardi, G. Malpeli, and F. Bifari Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow PLoS One 7 2012 e35639
-
(2012)
PLoS One
, vol.7
, pp. 35639
-
-
Ricciardi, M.1
Malpeli, G.2
Bifari, F.3
-
232
-
-
47249135404
-
Airway epithelial cell senescence in the lung allograft
-
S.M. Parker, M.R. Goriwiec, and L.A. Borthwick Airway epithelial cell senescence in the lung allograft Am J Transplant 8 2008 1544 1549
-
(2008)
Am J Transplant
, vol.8
, pp. 1544-1549
-
-
Parker, S.M.1
Goriwiec, M.R.2
Borthwick, L.A.3
-
233
-
-
49449100143
-
Bronchiolitis
-
U. Costabel, R.M. du Bois, J.J. Egan, Karger Basel
-
V. Poletti, G. Casoni, M. Zompatori, and M. Chilosi Bronchiolitis U. Costabel, R.M. du Bois, J.J. Egan, Diffuse parenchymal lung disease 2007 Karger Basel 292 306
-
(2007)
Diffuse Parenchymal Lung Disease
, pp. 292-306
-
-
Poletti, V.1
Casoni, G.2
Zompatori, M.3
Chilosi, M.4
-
234
-
-
43049158102
-
An international collaborative pathologic study of surgical lung biopsies from mustard gas-exposed patients
-
M. Ghanei, H.D. Tazelaar, and M. Chilosi An international collaborative pathologic study of surgical lung biopsies from mustard gas-exposed patients Respir Med 102 2008 825 830
-
(2008)
Respir Med
, vol.102
, pp. 825-830
-
-
Ghanei, M.1
Tazelaar, H.D.2
Chilosi, M.3
-
235
-
-
58149141748
-
Constrictive bronchiolitis associated with paraneoplastic autoimmune multi-organ syndrome
-
F. Maldonado, M.R. Pittelkow, and J.H. Ryu Constrictive bronchiolitis associated with paraneoplastic autoimmune multi-organ syndrome Respirology 14 2009 129 133
-
(2009)
Respirology
, vol.14
, pp. 129-133
-
-
Maldonado, F.1
Pittelkow, M.R.2
Ryu, J.H.3
-
236
-
-
84455207428
-
Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease
-
V. Amsellem, G. Gary-Bobo, and E. Marcos Telomere dysfunction causes sustained inflammation in chronic obstructive pulmonary disease Am J Respir Crit Care Med 184 2011 1358 1366
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 1358-1366
-
-
Amsellem, V.1
Gary-Bobo, G.2
Marcos, E.3
-
237
-
-
84869879700
-
Repair of tracheal epithelium by basal cells after chlorine-induced injury
-
S. Musah, J. Chen, and G.W. Hoyle Repair of tracheal epithelium by basal cells after chlorine-induced injury Respir Res 13 2012 107
-
(2012)
Respir Res
, vol.13
, pp. 107
-
-
Musah, S.1
Chen, J.2
Hoyle, G.W.3
-
238
-
-
73149118480
-
The aging immune system and its relationship to the development of chronic obstructive pulmonary disease
-
G. Sharma, N.A. Hanania, and Y.M. Shim The aging immune system and its relationship to the development of chronic obstructive pulmonary disease Proc Am Thorac Soc 6 2009 573 580
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 573-580
-
-
Sharma, G.1
Hanania, N.A.2
Shim, Y.M.3
-
239
-
-
33747600439
-
Systemic inflammation in patients with COPD and pulmonary hypertension
-
P. Joppa, D. Petrasova, B. Stancak, and R. Tkacova Systemic inflammation in patients with COPD and pulmonary hypertension Chest 130 2006 326 333
-
(2006)
Chest
, vol.130
, pp. 326-333
-
-
Joppa, P.1
Petrasova, D.2
Stancak, B.3
Tkacova, R.4
-
240
-
-
84867162444
-
Role of histone deacetylase 2 in epigenetics and cellular senescence: Implications in lung inflammaging and COPD
-
H. Yao, and I. Rahman Role of histone deacetylase 2 in epigenetics and cellular senescence: implications in lung inflammaging and COPD Am J Physiol Lung Cell Mol Physiol 303 2012 L557 L566
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
-
-
Yao, H.1
Rahman, I.2
-
241
-
-
73149091434
-
Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease
-
K. Aoshiba, and A. Nagai Senescence hypothesis for the pathogenetic mechanism of chronic obstructive pulmonary disease Proc Am Thorac Soc 6 2009 596 601
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 596-601
-
-
Aoshiba, K.1
Nagai, A.2
-
242
-
-
26844449508
-
Combined pulmonary fibrosis and emphysema: A distinct underrecognised entity
-
V. Cottin, H. Nunes, and P.Y. Brillet Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity Eur Respir J 26 2005 586 593
-
(2005)
Eur Respir J
, vol.26
, pp. 586-593
-
-
Cottin, V.1
Nunes, H.2
Brillet, P.Y.3
-
243
-
-
75149155845
-
Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome
-
V. Cottin, J. Le Pavec, and G. Prévot Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome Eur Respir J 35 2010 105 111
-
(2010)
Eur Respir J
, vol.35
, pp. 105-111
-
-
Cottin, V.1
Le Pavec, J.2
Prévot, G.3
-
244
-
-
84867903345
-
Combined pulmonary fibrosis and emphysema syndrome in systemic sclerosis
-
C. Lubatti, S. Zeni, and F. Ingegnoli Combined pulmonary fibrosis and emphysema syndrome in systemic sclerosis Int J Rheum Dis 15 2012 e122 e123
-
(2012)
Int J Rheum Dis
, vol.15
-
-
Lubatti, C.1
Zeni, S.2
Ingegnoli, F.3
-
245
-
-
84864768081
-
Combined pulmonary fibrosis and emphysema associated with microscopic polyangiitis
-
A. Tzouvelekis, G. Zacharis, and A. Oikonomou Combined pulmonary fibrosis and emphysema associated with microscopic polyangiitis Eur Respir J 40 2012 505 507
-
(2012)
Eur Respir J
, vol.40
, pp. 505-507
-
-
Tzouvelekis, A.1
Zacharis, G.2
Oikonomou, A.3
-
246
-
-
84864869958
-
Combined pulmonary fibrosis and emphysema in connective tissue disease
-
V. Cottin, and J.F. Cordier Combined pulmonary fibrosis and emphysema in connective tissue disease Curr Opin Pulmon Med 18 2012 418 427
-
(2012)
Curr Opin Pulmon Med
, vol.18
, pp. 418-427
-
-
Cottin, V.1
Cordier, J.F.2
-
247
-
-
84880082256
-
Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis
-
C.J. Ryerson, T. Hartman, and B.M. Elicker Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis Chest 144 2013 234 240
-
(2013)
Chest
, vol.144
, pp. 234-240
-
-
Ryerson, C.J.1
Hartman, T.2
Elicker, B.M.3
-
248
-
-
84866111123
-
Characteristics of pulmonary inflammation in combined pulmonary fibrosis and emphysema
-
Y. Zhao, A. Cui, and F. Wang Characteristics of pulmonary inflammation in combined pulmonary fibrosis and emphysema Chin Med J (Engl) 125 2012 3015 3021
-
(2012)
Chin Med J (Engl)
, vol.125
, pp. 3015-3021
-
-
Zhao, Y.1
Cui, A.2
Wang, F.3
-
249
-
-
80053250869
-
Combined pulmonary fibrosis and emphysema syndrome associated with familial SFTPC mutation
-
V. Cottin, P. Reix, C. Khouatra, F. Thivolet-Béjui, D. Feldmann, and J.F. Cordier Combined pulmonary fibrosis and emphysema syndrome associated with familial SFTPC mutation Thorax 66 2011 918 919
-
(2011)
Thorax
, vol.66
, pp. 918-919
-
-
Cottin, V.1
Reix, P.2
Khouatra, C.3
Thivolet-Béjui, F.4
Feldmann, D.5
Cordier, J.F.6
-
250
-
-
84880571140
-
Reversing T cell immunosenescence: Why, who, and how
-
P.O. Lang, S. Govind, and R. Aspinall Reversing T cell immunosenescence: why, who, and how Age (Dordr) 35 2013 609 620
-
(2013)
Age (Dordr)
, vol.35
, pp. 609-620
-
-
Lang, P.O.1
Govind, S.2
Aspinall, R.3
-
251
-
-
84877064267
-
Redox regulation of SIRT1 in inflammation and cellular senescence
-
J.W. Hwang, H. Yao, S. Caito, I.K. Sundar, and I. Rahman Redox regulation of SIRT1 in inflammation and cellular senescence Free Radic Biol Med 61 2013 95 100
-
(2013)
Free Radic Biol Med
, vol.61
, pp. 95-100
-
-
Hwang, J.W.1
Yao, H.2
Caito, S.3
Sundar, I.K.4
Rahman, I.5
-
252
-
-
84876124887
-
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
-
I.K. Sundar, H. Yao, and I. Rahman Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases Antioxid Redox Signal 18 2013 1956 1971
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1956-1971
-
-
Sundar, I.K.1
Yao, H.2
Rahman, I.3
-
253
-
-
84860880317
-
SIRT1 as a therapeutic target in inflammaging of the pulmonary disease
-
I. Rahman, V.L. Kinnula, V. Gorbunova, and H. Yao SIRT1 as a therapeutic target in inflammaging of the pulmonary disease Prev Med 54 2012 S20 S28
-
(2012)
Prev Med
, vol.54
-
-
Rahman, I.1
Kinnula, V.L.2
Gorbunova, V.3
Yao, H.4
-
254
-
-
77956241957
-
Stem cells and cell therapy approaches in lung biology and diseases
-
V. Sueblinvong, and D.J. Weiss Stem cells and cell therapy approaches in lung biology and diseases Transl Res 156 2010 188 205
-
(2010)
Transl Res
, vol.156
, pp. 188-205
-
-
Sueblinvong, V.1
Weiss, D.J.2
-
255
-
-
79959461779
-
Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+ CD25+ forkhead box p3 (FOXP3)+ regulatory T cells and balancing anti- and pro-inflammatory factors
-
J. Sun, Z.B. Han, and W. Liao Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+ CD25+ forkhead box p3 (FOXP3)+ regulatory T cells and balancing anti- and pro-inflammatory factors Cell Physiol Biochem 27 2011 587 596
-
(2011)
Cell Physiol Biochem
, vol.27
, pp. 587-596
-
-
Sun, J.1
Han, Z.B.2
Liao, W.3
-
256
-
-
84875186801
-
Pluripotent stem cells and gene therapy
-
P. Simara, J.A. Motl, and D.S. Kaufman Pluripotent stem cells and gene therapy Transl Res 161 2013 284 292
-
(2013)
Transl Res
, vol.161
, pp. 284-292
-
-
Simara, P.1
Motl, J.A.2
Kaufman, D.S.3
-
257
-
-
84873116668
-
Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions
-
A.I. Papaioannou, C. Rossios, K. Kostikas, and K. Ito Can we delay the accelerated lung aging in COPD? Anti-aging molecules and interventions Curr Drug Targets 14 2013 149 157
-
(2013)
Curr Drug Targets
, vol.14
, pp. 149-157
-
-
Papaioannou, A.I.1
Rossios, C.2
Kostikas, K.3
Ito, K.4
-
258
-
-
84872231816
-
Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease
-
K. Ito, T. Colley, and N. Mercado Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease Int J Chron Obstruct Pulmon Dis 7 2012 641 652
-
(2012)
Int J Chron Obstruct Pulmon Dis
, vol.7
, pp. 641-652
-
-
Ito, K.1
Colley, T.2
Mercado, N.3
|