STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF

American Journal of Pathology

Volumn 180, Issue 4, 2012, Pages 1398-1412

  Pechkovsky, Dmitri V ^a,b   Prêle, Cecilia M ^c   Wong, John ^a   Hogaboam, Cory M ^d   McAnulty, Robin J ^e   Laurent, Geoffrey J ^e   Zhang, Samuel S M ^f   Selman, Moisés ^g   Mutsaers, Steven E ^c   Knight, Darryl A ^a,b  

^a ST PAUL S HOSPITAL   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f PENN STATE COLLEGE OF MEDICINE   (United States)

^g INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA5 INTEGRIN; COLLAGEN TYPE 1; INTERLEUKIN 6; ONCOSTATIN M; SMAD3 PROTEIN; SMAD7 PROTEIN; STAT3 PROTEIN; STAUROSPORINE; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; VITRONECTIN RECEPTOR;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FIBROSING ALVEOLITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL PNEUMONIA; LUNG FIBROBLAST; MYOFIBROBLAST; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTINS; ANTIGENS, THY-1; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; DOWN-REGULATION; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; INTEGRIN ALPHAVBETA3; INTERLEUKIN-6; LUNG; MYOFIBROBLASTS; ONCOSTATIN M; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSDUCTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84859015820     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.12.022     Document Type: Article

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