Accelerated variant of idiopathic pulmonary fibrosis: Clinical behavior and gene expression pattern

PLoS ONE

Volumn 2, Issue 5, 2007, Pages

  Selman, Moisés ^a   Carrillo, Guillermo ^a   Estrada, Andrea ^a   Mejia, Mayra ^a   Becerril, Carina ^a   Cisneros, José ^a   Gaxiola, Miguel ^a   Pérez Padilla, Rogelio ^a   Navarro, Carmen ^a   Richards, Thomas ^b   Dauber, James ^b   King Jr , Talmadge E ^c   Pardo, Annie ^d   Kaminski, Naftali ^b  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c SAN FRANCISCO GENERAL HOSPITAL   (United States)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE 2B RECEPTOR; ADENOSINE RECEPTOR; AZATHIOPRINE; BECLOMETASONE; CD133 ANTIGEN; COLCHICINE; GELATINASE B; PREDNISONE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FIBROSING ALVEOLITIS; FOLLOW UP; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MORPHOGENESIS; OXIDATIVE STRESS; PHENOTYPE; PROPORTIONAL HAZARDS MODEL; SMOKING; SMOOTH MUSCLE FIBER; SURVIVAL RATE; SURVIVAL TIME; TISSUE MICROARRAY; UPREGULATION; AGED; DNA MICROARRAY; GENETIC TRANSCRIPTION; GENETICS; LUNG FIBROSIS; LUNG FUNCTION TEST; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; PATHOPHYSIOLOGY; WESTERN BLOTTING;

AGED; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PULMONARY FIBROSIS; RESPIRATORY FUNCTION TESTS; SURVIVAL RATE; TRANSCRIPTION, GENETIC;

EID: 37549060070     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000482     Document Type: Article

References (45)

1. Gross TJ, Hunninghake GW (2001) Idiopathic pulmonary fibrosis. N Engl J Med 345: 517-525.
2. Collard HR, Ryu JH, Douglas WW, Schwarz MI, Curran-Everett D, et al. (2004) Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis. Chest 125: 2169-2174.
3. Selman M, King TE, Pardo A (2001) Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134: 136-151.
4. McCormack FX, King TE Jr, Bucher BL, Nielsen L, Mason RJ (1995) Surfactant protein A predicts survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 152: 751-759.
5. Martinez FJ, Safrin S, Weycker D, Starko KM, Bradford WZ, et al. (2005) The clinical course of patients with idiopathic pulmonary fibrosis. Ann Intern Med 142: 963-967.
6. Ambrosini V, Cancellieri A, Chilosi M, Zompatori M, Trisolini R, et al. (2003) Acute exacerbation of idiopathic pulmonary fibrosis: report of a series. Eur Respir J 22: 821-826.
7. American Thoracic Society (2000) Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS) and the European Respiratory Society (ERS) Am J Respir Crit Care Med 161: 646-664.
8. King TE Jr, Tooze JA, Schwarz MI, Brown KR, Cherniack RM (2001) Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. Am J Respir Crit Care Med 164: 1171-1181.
9. Selman M, Carrillo G, Salas J, Padilla RP, Perez-Chavira R, et al. (1998) Colchicine, D-penicillamine, and prednisone in the treatment of idiopathic pulmonary fibrosis: a controlled clinical trial. Chest 114: 507-512.
10. Kazerooni EA, Martinez FJ, Flint A, Jamadar DA, Gross BH, et al. (1997) Thin-section CT obtained at 10-mm increments versus limited three-level thin-section CT for idiopathic pulmonary fibrosis: correlation with pathologic scoring. AJR Am J Roentgenol 169: 977-983.
11. Pardo A, Gibson K, Cisneros J, Richards TJ, Yang Y, et al. (2005) Upregulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis. PLoS Med 2: e251.
12. Selman M, Ruiz V, Cabrera S, Segura L, Ramirez R, et al. (2000) TIMP 1, 2, 3, and 4 in idiopathic pulmonary fibrosis: a prevailing nondegradative lung microenvironment? Am J Physiol 279: L562-574.
13. Selman M, Pardo A, Barrera L, Estrada A, Watson SR, et al. (2006) Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis. Am J Respir Crit Care Med 173: 188-198.
14. Perez-Padilla R, Salas J, Chapela R, Sanchez M, Carrillo G, et al. (1993) Mortality in Mexican patients with chronic pigeon breeder's lung compared with those with usual interstitial pneumonia. Am Rev Respir Dis 148: 49-53.
15. Hyde DM, King TE Jr, McDermott T, Waldron JA Jr, Colby TV, et al. (1992) Idiopathic pulmonary fibrosis. Quantitative assessment of lung pathology. Comparison of a semiquantitative and a morphometric histopathologic scoring system. Am Rev Respir Dis 146: 1042-1047.
16. Cisneros-Lira J, Gaxiola M, Ramos C, Selman M, Pardo A (2003) Cigarette smoke exposure potentiates bleomycin-induced lung fibrosis in guinea pigs. Am J Physiol 285: L949-956.
17. Kaminski N, Friedman N (2002) Practical approaches to analyzing results of microarray experiments. Am J Respir Cell Mol Biol 27: 125-132.
18. Segal E, Friedman N, Kaminski N, Regev A, Koller D (2005) From signatures to models: understanding cancer using microarrays. Nat Genet 37 Suppl: S38-45.
19. Ben-Dor A, Bruhn L, Friedman N, Nachman I, Schummer M, et al. (2000) Tissue classification with gene expression profiles. J Comput Biol 7: 559-83.
20. Radom-Aizik S, Hayek S, Shahar I, Rechavi G, Kaminski N, et al. (2005) Effects of aerobic training on gene expression in skeletal muscle of elderly men. Med Sci Sports Exerc 37: 1680-1696.
21. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc B 57: 289-300.
22. Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 98: 5116-5121.
23. Hogan CM, Hammer SM (2001) Host determinants in HIV infection and disease. Part 1: cellular and humoral immune responses. Ann Intern Med 134: 761-776.
24. Marshall A, Rushbrook S, Morris LS, Scott IS, Vowler SL, et al. (2005) Hepatocyte expression of minichromosome maintenance protein-2 predicts fibrosis progression after transplantation for chronic hepatitis C virus: A pilot study. Liver Transpl 11: 427-433.
25. Bolton WK, Abdel-Rahman E (2001) Pathogenesis of focal glomerulosclerosis. Nephron 88: 6-13.
26. He JQ, Ruan J, Connett JE, Anthonisen NR, Pare PD, et al. (2002) Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers. Am J Respir Crit Care Med 166: 323-328.
27. Egan JJ, Martinez FJ, Wells AU, Williams T (2005) Lung function estimates in idiopathic pulmonary fibrosis: the potential for a simple classification. Thorax 60: 270-273.
28. Gay SE, Kazerooni EA, Toews GB, Lynch JP 3rd, Gross BH, et al. (1998) Idiopathic pulmonary fibrosis: predicting response to therapy and survival. Am J Respir Crit Care Med 157: 1063-1072.
29. Heguy A, O'Connor TP, Luettich K, Worgall S, Cieciuch A, et al. (2006) Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. J Mol Med 84: 318-328.
30. Woodruff PG, Koth LL, Yang YH, Rodriguez MW, Favoreto S, et al. (2005) A distinctive alveolar macrophage activation state induced by cigarette smoking. Am J Respir Crit Care Med 172: 1383-1392.
31. Ning W, Li CJ, Kaminski N, Feghali-Bostwick CA, Alber SM, et al. (2004) Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 101: 14895-14900.
32. Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, et al. (2007) Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med 85: 39-53.
33. Zhong H, Belardinelli L, Maa T, Zeng D (2005) Synergy between A2B adenosine receptors and hypoxia in activating human lung fibroblasts. Am J Respir Cell Mol Biol 32: 2-8.
34. Chunn JL, Mohsenin A, Young HW, Lee CG, Elias JA, et al. (2006) Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. Am J Physiol Lung Cell Mol Physiol 290: L579-587.
35. Kania G, Corbeil D, Fuchs J, Tarasov KV, Blyszczuk P, et al. (2005) Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors. Stem Cells 23: 791-804.
36. Shmelkov SV, St Clair R, Lyden D, Rafii S (2005) AC133/CD133/Prominin-1. Int J Biochem Cell Biol 37: 715-719.
37. Gahl WA, Brantly M, Troendle J, Avila NA, Padua A, et al. (2002) Effect of pirfenidone on the pulmonary fibrosis of Hermansky-Pudlak syndrome. Mol Genet Metab 76: 234-242.
38. Demling N, Ehrhardt C, Kasper M, Laue M, Knels L, et al. (2006) Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 323: 475-488.
39. Hanford LE, Fattman CL, Shaefer LM, Enghild JJ, Valnickova Z, et al. (2003) Regulation of receptor for advanced glycation end products during bleomycin-induced lung injury. Am J Respir Cell Mol Biol 29 (3 Suppl): S77-81.
40. Pardo A, Ruiz V, Arreola JL, Ramirez R, Cisneros-Lira J, et al. (2003) Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice. Am J Respir Crit Care Med 167: 925-932.
41. Fukuda Y, Ishizaki M, Kudoh S, Kitaichi M, Yamanaka N (1998) Localization of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases. Lab Invest 78: 687-698.
42. Atkinson JJ, Senior RM (2003) Matrix metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol 28: 12-24.
43. Yu Q, Stamenkovic I (2000) Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev 14: 163-176.
44. Carr BA, Wan J, Hines RN, Yost GS (2003) Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif. J Biol Chem 278: 15473-15483.
45. Raghu G, Brown KK, Bradford WZ, Starko K, Noble PW, et al. (2004) Idiopathic Pulmonary Fibrosis Study Group. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 350: 125-133.