Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 6, 2008, Pages

  Lawson, William E ^a,b   Crossno, Peter F ^a   Polosukhin, Vasiliy V ^a   Roldan, Juan ^a,c   Cheng, Dong Sheng ^a   Lane, Kirk B ^a   Blackwell, Thomas R ^a   Xu, Carol ^a   Markin, Cheryl ^a   Ware, Lorraine B ^a   Miller, Geraldine G ^a   Loyd, James E ^a   Blackwell, Timothy S ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Lung; Surfactant protein C; Unfolded protein response; Usual interstitial pneumonia

Indexed keywords

SURFACTANT PROTEIN C; VIRUS PROTEIN; ALPHA MANNOSIDASE; CHAPERONE; DNA BINDING PROTEIN; EDEM2 PROTEIN, HUMAN; GLYCOPROTEIN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; NUCLEAR PROTEIN; SFTPC PROTEIN, HUMAN; TRE BINDING PROTEIN; TRE-BINDING PROTEIN; VIRUS ANTIGEN;

ARTICLE; CELL STRESS; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM; FIBROSING ALVEOLITIS; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL PNEUMONIA; LUNG ALVEOLUS EPITHELIUM; LUNG BIOPSY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; SFTPC GENE; VIRUS INFECTION; BIOSYNTHESIS; CELL CULTURE; GENETICS; HERPES VIRUS INFECTION; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS; LUNG FIBROSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN FOLDING; STRESS; ULTRASTRUCTURE;

ALPHA-MANNOSIDASE; ANTIGENS, VIRAL; CELLS, CULTURED; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; GLYCOPROTEINS; HEAT-SHOCK PROTEINS; HERPESVIRIDAE INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; PROTEIN FOLDING; PULMONARY ALVEOLI; PULMONARY FIBROSIS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; STRESS;

EID: 48949119341     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00382.2007     Document Type: Article

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