Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 181, Issue 3, 2010, Pages 254-263

  Sisson, Thomas H ^a   Mendez, Michael ^b   Choi, Karen ^a   Subbotina, Natalya ^a   Courey, Anthony ^a   Cunningham, Andrew ^a   Dave, Aditi ^a   Engelhardt, John F ^c   Liu, Xiaoming ^c   White, Eric S ^a   Thannickal, Victor J ^a   Moore, Bethany B ^a   Christensen, Paul J ^b   Simon, Richard H ^a  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

Collagen; Diphtheria toxin; Lung; Scarring

Indexed keywords

COLLAGEN; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN RECEPTOR; HYDROXYPROLINE; RECEPTOR; SURFACTANT PROTEIN C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DAMAGE; CONTROLLED STUDY; DISEASE ASSOCIATION; GENETIC TRANSFECTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS EPITHELIUM TYPE II; LUNG FIBROSIS; MEASUREMENT; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; SCAR FORMATION; SURVIVAL; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GENOTYPE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDES; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 76749165460     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200810-1615OC     Document Type: Article

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