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Volumn 25, Issue 5, 2009, Pages 1235-1245

Progression of chronic obstructive pulmonary disease: Impact of inflammation, comorbidities and therapeutic intervention

Author keywords

Chronic obstructive pulmonary disease; Comorbidity; Disease progression; Inflammation; Inhaled corticosteroid; Long acting beta agonist

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CORTICOSTEROID; FLUTICASONE PROPIONATE PLUS SALMETEROL; FORMOTEROL; INFLIXIMAB; INTERLEUKIN 6; INTERLEUKIN 8; LONG ACTING DRUG; SALMETEROL; TIOTROPIUM BROMIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 67649224269     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007990902868971     Document Type: Review
Times cited : (63)

References (118)
  • 1
    • 67649414712 scopus 로고    scopus 로고
    • Available at: [Last accessed 18 February 2009]
    • Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2007. Available at: www.goldcopd.com [Last accessed 18 February 2009]
    • (2007)
  • 2
    • 77249136293 scopus 로고    scopus 로고
    • Available at: [Last accessed 18 February 2009]
    • World Health Organization (WHO). Chronic Obstructive Pulmonary Disease. 2007. Available at: www.who.int/respiratory/ copd/ [Last accessed 18 February 2009]
    • (2007) Chronic Obstructive Pulmonary Disease
  • 3
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997;349:1498-1504
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 5
    • 33748782303 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: The disease and its burden to society
    • DOI 10.1513/pats.200603-093SS
    • Halpin DM, Miravitlles M. Chronic obstructive pulmonary disease: the disease and its burden to society. ProcAm Thoracic Soc 2006;3:619-623 (Pubitemid 44411630)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.7 , pp. 619-623
    • Halpin, D.M.G.1    Miravitlles, M.2
  • 6
    • 0037336007 scopus 로고    scopus 로고
    • Costs of chronic bronchitis and COPD: A 1-year follow-up study
    • on behalf of the DAFNE Study Group
    • Miravitlles M, Murio C, Guerrero T et al, on behalf of the DAFNE Study Group. Costs of chronic bronchitis and COPD: a 1-year follow-up study. Chest 2003;123:784-791
    • (2003) Chest , vol.123 , pp. 784-791
    • Miravitlles, M.1    Murio, C.2    Guerrero, T.3
  • 7
    • 0037372035 scopus 로고    scopus 로고
    • Economic analysis of the Confronting COPD survey: An overview of results
    • DOI 10.1016/S0954-6111(03)80010-0
    • Wouters EF. Economic analysis of the Confronting COPD Survey: an overview of results. Respir Med 2003;97(Suppl. C):S3-14 (Pubitemid 36266865)
    • (2003) Respiratory Medicine , vol.97 , Issue.SUPPL. C
    • Wouters, E.F.M.1
  • 8
    • 0036739118 scopus 로고    scopus 로고
    • The costs of exacerbations in chronic obstructive pulmonary disease (COPD)
    • Andersson F, Borg S, Jansson SA, et al. The costs of exacerbations in chronic obstructive pulmonary disease (COPD). Respir Med 2002;96:700-708
    • (2002) Respir Med , vol.96 , pp. 700-708
    • Andersson, F.1    Borg, S.2    Jansson, S.A.3
  • 9
    • 33845677918 scopus 로고    scopus 로고
    • The workplace impact of acute exacerbations of chronic bronchitis (AECB): A literature review
    • Halpern MT, Polzin J, Higashi MK, et al. The workplace impact of acute exacerbations of chronic bronchitis (AECB): a literature review. COPD 2004;1:249-254
    • (2004) COPD , vol.1 , pp. 249-254
    • Halpern, M.T.1    Polzin, J.2    Higashi, M.K.3
  • 10
    • 7944238611 scopus 로고    scopus 로고
    • Living with severe chronic obstructive pulmonary disease (COPD): Perceptions of patients and their carers. An interpretative phenomenological analysis
    • Seamark DA, Blake SD, Seamark CJ, et al. Living with severe chronic obstructive pulmonary disease (COPD): perceptions of patients and their carers. An interpretative phenomenological analysis. Palliat Med 2004;18:619-625
    • (2004) Palliat Med , vol.18 , pp. 619-625
    • Seamark, D.A.1    Blake, S.D.2    Seamark, C.J.3
  • 11
    • 0036798971 scopus 로고    scopus 로고
    • Impact of COPD in North America and Europe in 2000: Subjects' perspective of Confronting COPD International Survey
    • Rennard S, Decramer M, Calverley PM, et al. Impact of COPD in North America and Europe in 2000: subjects' perspective of Confronting COPD International Survey. Eur Respir J 2002;20:799-805
    • (2002) Eur Respir J , vol.20 , pp. 799-805
    • Rennard, S.1    Decramer, M.2    Calverley, P.M.3
  • 14
    • 0141483616 scopus 로고    scopus 로고
    • Management of COPD according to guidelines. A national survey among Belgian physicians
    • Decramer M, Bartsch P, Pauwels R, et al. Management of COPD according to guidelines. A national survey among Belgian physicians. Monaldi Arch Chest Dis 2003;59:62-80
    • (2003) Monaldi Arch Chest Dis , vol.59 , pp. 62-80
    • Decramer, M.1    Bartsch, P.2    Pauwels, R.3
  • 15
    • 0037362029 scopus 로고    scopus 로고
    • Approaches to slowing the progression of COPD
    • DOI 10.1097/00063198-200303000-00006
    • Altose MD. Approaches to slowing the progression of COPD. Curr Opin Pulm Med 2003;9:125-130 (Pubitemid 36184563)
    • (2003) Current Opinion in Pulmonary Medicine , vol.9 , Issue.2 , pp. 125-130
    • Altose, M.D.1
  • 16
    • 18244367647 scopus 로고    scopus 로고
    • COPD, a multicomponent disease: Implications for management
    • DOI 10.1016/j.rmed.2004.11.006, PII S0954611104004330
    • Agusti AG. COPD, a multicomponent disease: implications for management. Respir Med 2005;99:670-682 (Pubitemid 40631293)
    • (2005) Respiratory Medicine , vol.99 , Issue.6 , pp. 670-682
    • Agusti, A.G.N.1
  • 18
    • 3142517968 scopus 로고    scopus 로고
    • Association between chronic obstructive pulmonary disease and systemic inflammation: A systematic review and a meta-analysis
    • DOI 10.1136/thx.2003.019588
    • Gan WQ, Man SFP, Senthilselvan A, et al. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and meta-analysis. Thorax 2004;59:574-580 (Pubitemid 38901515)
    • (2004) Thorax , vol.59 , Issue.7 , pp. 574-580
    • Gan, W.Q.1    Man, S.F.P.2    Senthilselvan, A.3    Sin, D.D.4
  • 20
    • 33745209743 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease, inflammation and co-morbidity - A common inflammatory phenotype?
    • Sevenoaks MJ, Stockley RA. Chronic obstructive pulmonary disease, inflammation and co-morbidity - a common inflammatory phenotype? Respir Res 2006;7:70
    • (2006) Respir Res , vol.7 , pp. 70
    • Sevenoaks, M.J.1    Stockley, R.A.2
  • 22
    • 23144463566 scopus 로고    scopus 로고
    • Are patients with COPD psychologically distressed?
    • Wagena EJ, Arrindell WA, Wouters EF, et al. Are patients with COPD psychologically distressed? Eur Respir J 2005;26:242-248
    • (2005) Eur Respir J , vol.26 , pp. 242-248
    • Wagena, E.J.1    Arrindell, W.A.2    Wouters, E.F.3
  • 23
    • 17644397560 scopus 로고    scopus 로고
    • Local and systemic inflammation in chronic obstructive pulmonary disease
    • DOI 10.1513/pats.200408-039MS
    • Wouters EF. Local and systemic inflammation in chronic obstructive pulmonary disease. Proc Am Thoracic Soc 2005;2:26-33 (Pubitemid 40562960)
    • (2005) Proceedings of the American Thoracic Society , vol.2 , Issue.1 , pp. 26-33
    • Wouters, E.F.M.1
  • 24
    • 10644266789 scopus 로고    scopus 로고
    • Mediators of chronic obstructive pulmonary disease
    • DOI 10.1124/pr.56.4.2
    • Barnes PJ. Mediators of chronic obstructive pulmonary disease. Pharmacol Rev 2004;56:515-548 (Pubitemid 39658462)
    • (2004) Pharmacological Reviews , vol.56 , Issue.4 , pp. 515-548
    • Barnes, P.J.1
  • 25
    • 24944464002 scopus 로고    scopus 로고
    • Remodelling and inflammation of bronchia in asthma and chronic obstructive pulmonary disease
    • Jeffery PK. Remodelling and inflammation of bronchia in asthma and chronic obstructive pulmonary disease. Proc Am Thoracic Soc 2004;1:176-183
    • (2004) Proc Am Thoracic Soc , vol.1 , pp. 176-183
    • Jeffery, P.K.1
  • 26
    • 21744448376 scopus 로고    scopus 로고
    • Alveolar macrophages in chronic obstructive pulmonary disease (COPD)
    • Online Pub: OL627-37
    • Barnes PJ. Alveolar macrophages in chronic obstructive pulmonary disease (COPD). Cell Mol Biol 2004;50:Online Pub: OL627-37
    • (2004) Cell Mol Biol , vol.50
    • Barnes, P.J.1
  • 27
    • 33750627155 scopus 로고    scopus 로고
    • Alveolar macrophages as orchestrators of COPD
    • Barnes PJ. Alveolar macrophages as orchestrators of COPD. COPD 2004;1:59-70
    • (2004) COPD , vol.1 , pp. 59-70
    • Barnes, P.J.1
  • 28
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
    • DOI 10.1016/S0140-6736(04)16900-6, PII S0140673604169006
    • Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004;364:709-721 (Pubitemid 39140629)
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 709-721
    • Hogg, J.C.1
  • 30
    • 0036264599 scopus 로고    scopus 로고
    • Neutrophils and the pathogenesis of COPD
    • Stockley RA. Neutrophils and the pathogenesis of COPD. Chest 2002;121:151S-5S (Pubitemid 34497333)
    • (2002) Chest , vol.121 , Issue.5 SUPPL.
    • Stockley, R.A.1
  • 31
    • 0038434032 scopus 로고    scopus 로고
    • Obstructive and restrictive lung disease and markers of inflammation: Data from the third national health and nutrition examination
    • DOI 10.1016/S0002-9343(03)00185-2
    • Mannino DM, Ford ES, Redd SC. Obstructive and restrictive lung disease and markers of inflammation: data from the Third National Health and Nutrition Examination. Am J Med 2003;114:758-762 (Pubitemid 36776358)
    • (2003) American Journal of Medicine , vol.114 , Issue.9 , pp. 758-762
    • Mannino, D.M.1    Ford, E.S.2    Redd, S.C.3
  • 32
    • 0033865911 scopus 로고    scopus 로고
    • Acute exacerbations of COPD are accompanied by elevations of plasma fibrinogen and serum IL-6 levels
    • Wedzicha JA, Seemungal TA, MacCallum PK, et al. Acute exacerbations of COPD are accompanied by elevations of plasma fibrinogen and serum IL-6 levels. Thromb Haemost 2000;84:210-215
    • (2000) Thromb Haemost , vol.84 , pp. 210-215
    • Wedzicha, J.A.1    Seemungal, T.A.2    MacCallum, P.K.3
  • 33
    • 33646554531 scopus 로고    scopus 로고
    • Inflammatory cells in the airways in COPD
    • DOI 10.1136/thx.2004.024463
    • O'Donnell R, Breen D, Wilson S, et al. Inflammatory cells in the airways in COPD. Thorax 2006;61:448-454 (Pubitemid 43723331)
    • (2006) Thorax , vol.61 , Issue.5 , pp. 448-454
    • O'Donnell, R.1    Breen, D.2    Wilson, S.3    Djukanovic, R.4
  • 34
    • 20144372491 scopus 로고    scopus 로고
    • A two-stage logistic model based on the measurement of pro-inflammatory cytokines in bronchial secretions for assessing bacterial, viral, and non-infectious origin of COPD exacerbations
    • DOI 10.1081/COPD-200050680
    • Dal Negro RW, Micheletto C, Tognella S, et al. A two-stage logistic model based on the measurement of pro-inflammatory cytokines in bronchial secretions for assessing bacterial, viral, and non-infectious origin of COPD exacerbations. COPD 2005;2:7-16 (Pubitemid 40776217)
    • (2005) COPD: Journal of Chronic Obstructive Pulmonary Disease , vol.2 , Issue.1 , pp. 7-16
    • Dal Negro, R.W.1    Micheletto, C.2    Tognella, S.3    Visconti, M.4    Guerriero, M.5    Sandri, M.F.6
  • 36
    • 0018651591 scopus 로고
    • 1-antitrypsin and leukocyte elastase in infected and noninfected sputum
    • Stockley RA, Burnett D. Alpha,-antitrypsin and leukocyte elastase in infected and noninfected sputum. Am Rev Respir Dis 1979;120:1081-1086 (Pubitemid 10218496)
    • (1979) American Review of Respiratory Disease , vol.120 , Issue.5 , pp. 1081-1086
    • Stockley, R.A.1    Burnett, D.2
  • 40
    • 0034047904 scopus 로고    scopus 로고
    • Relationship of sputum color to nature and outpatient management of acute exacerbations of COPD
    • Stockley RA, O'Brien C, Pye A, et al. Relationship of sputum color to nature and outpatient management of acute exacerbations of COPD. Chest 2000;117:1638-1645 (Pubitemid 30413357)
    • (2000) Chest , vol.117 , Issue.6 , pp. 1638-1645
    • Stockley, R.A.1    O'Brien, C.2    Pye, A.3    Hill, S.L.4
  • 41
    • 0034883814 scopus 로고    scopus 로고
    • Changes in bronchial inflammation during acute exacerbations of chronic bronchitis
    • DOI 10.1183/09031936.01.99114901
    • Gompertz S, O'Brien C, Bayley DL, et al. Changes in bronchial inflammation during acute exacerbations of chronic bronchitis. Eur Respir J 2001;17:1112-1119 (Pubitemid 32717466)
    • (2001) European Respiratory Journal , vol.17 , Issue.6 , pp. 1112-1119
    • Gompertz, S.1    O'Brien, C.2    Bayley, D.L.3    Hill, S.L.4    Stockley, R.A.5
  • 45
    • 34748863974 scopus 로고    scopus 로고
    • Analysis of systemic biomarkers in COPD patients
    • Aldonyte R, Eriksson S, Piitulainen E, et al. Analysis of systemic biomarkers in COPD patients. COPD 2004;1:155-164
    • (2004) COPD , vol.1 , pp. 155-164
    • Aldonyte, R.1    Eriksson, S.2    Piitulainen, E.3
  • 46
    • 33646251821 scopus 로고    scopus 로고
    • Genetic association analysis of functional impairment in chronic obstructive pulmonary disease
    • Hersh CP, Demeo DL, Lazarus R, et al. Genetic association analysis of functional impairment in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006;173:977-984
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 977-984
    • Hersh, C.P.1    Demeo, D.L.2    Lazarus, R.3
  • 48
    • 33745021680 scopus 로고    scopus 로고
    • Systemic inflammation in COPD: Is genetic susceptibility a key factor?
    • Yanbaeva DG, Dentener MA, Creutzberg EC, et al. Systemic inflammation in COPD: is genetic susceptibility a key factor? COPD 2006;3:51-61
    • (2006) COPD , vol.3 , pp. 51-61
    • Yanbaeva, D.G.1    Dentener, M.A.2    Creutzberg, E.C.3
  • 49
    • 33646338189 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: Linking outcomes and pathobiology of disease modification
    • DOI 10.1513/pats.200512-129SF
    • Rennard SI. Chronic obstructive pulmonary disease: linking outcomes and pathobiology of disease modification. Proc Am Thoracic Soc 2006;3:276-280 (Pubitemid 43668194)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.3 , pp. 276-280
    • Rennard, S.I.1
  • 51
    • 33749998694 scopus 로고    scopus 로고
    • C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease
    • DOI 10.1136/thx.2006.059808
    • Man SF, Connett JE, Anthonisen NR, et al. C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease. Thorax 2006;61:849-853 (Pubitemid 44570304)
    • (2006) Thorax , vol.61 , Issue.10 , pp. 849-853
    • Man, S.F.P.1    Connett, J.E.2    Anthonisen, N.R.3    Wise, R.A.4    Tashkin, D.P.5    Sin, D.D.6
  • 52
    • 33845505080 scopus 로고    scopus 로고
    • Inflammation in sputum relates to progression of disease in subjects with COPD: A prospective descriptive study
    • DOI 10.1186/1465-9921-7-136
    • Parr DG, White AJ, Bayley DL, et al. Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study. Respir Res 2006;7:136 (Pubitemid 44911885)
    • (2006) Respiratory Research , vol.7 , pp. 136
    • Parr, D.G.1    White, A.J.2    Bayley, D.L.3    Guest, P.J.4    Stockley, R.A.5
  • 54
    • 33644985112 scopus 로고    scopus 로고
    • Markers of disease severity in chronic obstructive pulmonary disease
    • Franciosi LG, Page CP, Celli BR, et al. Markers of disease severity in chronic obstructive pulmonary disease. Pulm Pharmacol Ther 2006;19:189-199
    • (2006) Pulm Pharmacol Ther , vol.19 , pp. 189-199
    • Franciosi, L.G.1    Page, C.P.2    Celli, B.R.3
  • 55
    • 30844447198 scopus 로고    scopus 로고
    • Raised CRP levels mark metabolic and functional impairment in advanced COPD
    • DOI 10.1136/thx.2005.041996
    • Broekhuizen R, Wouters EF, Creutzberg EC, Schols AM. Raised CRP levels mark metabolic and functional impairment in advanced COPD. Thorax 2006;61:17-22 (Pubitemid 43106972)
    • (2006) Thorax , vol.61 , Issue.1 , pp. 17-22
    • Broekhuizen, R.1    Wouters, E.F.M.2    Creutzberg, E.C.3    Schols, A.M.W.J.4
  • 56
    • 0034018102 scopus 로고    scopus 로고
    • Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations
    • DOI 10.1136/thorax.55.2.114
    • Bhowmik A, Seemungal TA, Sapsford RJ, Wedzicha JA. Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000;55:114-120 (Pubitemid 30245950)
    • (2000) Thorax , vol.55 , Issue.2 , pp. 114-120
    • Bhowmik, A.1    Seemungal, T.A.R.2    Sapsford, R.J.3    Wedzicha, J.A.4
  • 59
    • 33847287411 scopus 로고    scopus 로고
    • Relationship between airway colonization, inflammation and exacerbation frequency in COPD
    • DOI 10.1016/j.rmed.2006.08.020, PII S0954611106004367
    • Tumkaya M, Atis S, Ozge C, et al. Relationship between airway colonization, inflammation and exacerbation frequency in COPD. Respir Med 2007;101:729-737 (Pubitemid 46317242)
    • (2007) Respiratory Medicine , vol.101 , Issue.4 , pp. 729-737
    • Tumkaya, M.1    Atis, S.2    Ozge, C.3    Delialioglu, N.4    Polat, G.5    Kanik, A.6
  • 64
    • 33744821605 scopus 로고    scopus 로고
    • Chemokine receptors in chronic obstructive pulmonary disease (COPD)
    • DOI 10.2174/138945006777435272
    • Panina P, Mariani M, D'Ambrosio D. Chemokine receptors in chronic obstructive pulmonary disease (COPD). Curr Drug Targets 2006;7:669-674 (Pubitemid 43827262)
    • (2006) Current Drug Targets , vol.7 , Issue.6 , pp. 669-674
    • Panina, P.1    Mariani, M.2    D'Ambrosio, D.3
  • 65
    • 0033835782 scopus 로고    scopus 로고
    • Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis
    • Hill AT, Campbell EJ, Hill SL, et al. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis. Am J Med 2000;109:288-295
    • (2000) Am J Med , vol.109 , pp. 288-295
    • Hill, A.T.1    Campbell, E.J.2    Hill, S.L.3
  • 67
    • 33750081753 scopus 로고    scopus 로고
    • Skeletal muscles in chronic obstructive pulmonary disease: Deconditioning, or myopathy?
    • DOI 10.1111/j.1440-1843.2006.00939.x
    • Wagner PD. Skeletal muscles in chronic obstructive pulmonary disease: deconditioning, or myopathy? Respirology 2006;11:681-686 (Pubitemid 44581430)
    • (2006) Respirology , vol.11 , Issue.6 , pp. 681-686
    • Wagner, P.D.1
  • 69
    • 8344234108 scopus 로고    scopus 로고
    • Cachexia in cancer - Zeroing in on myosin
    • DOI 10.1056/NEJMcibr042889
    • Chamberlain JS. Cachexia in cancer - zeroing in on myosin. N Engl J Med 2004;351:2124-2125 (Pubitemid 39482508)
    • (2004) New England Journal of Medicine , vol.351 , Issue.20 , pp. 2124-2125
    • Chamberlain, J.S.1
  • 72
    • 42949146028 scopus 로고    scopus 로고
    • Evaluation of COPD longitudinally to identify predictive surrogate end-points (ECLIPSE)
    • Vestbo J, Anderson W, Coxson HO, et al. Evaluation of COPD longitudinally to identify predictive surrogate end-points (ECLIPSE). Eur Respir J 2008;31:869-873
    • (2008) Eur Respir J , vol.31 , pp. 869-873
    • Vestbo, J.1    Anderson, W.2    Coxson, H.O.3
  • 73
    • 42649088839 scopus 로고    scopus 로고
    • Complex chronic comorbidities of COPD
    • Fabbri LM, Luppi F, Beghé B, et al. Complex chronic comorbidities of COPD. Eur Respir J 2008;31:204-212
    • (2008) Eur Respir J , vol.31 , pp. 204-212
    • Fabbri, L.M.1    Luppi, F.2    Beghé, B.3
  • 74
    • 35148893108 scopus 로고    scopus 로고
    • Systemic effects of chronic obstructive pulmonary disease: What we know and what we don't know (but should)
    • DOI 10.1513/pats.200701-004FM
    • Agusti A. Systemic effects of chronic obstructive pulmonary disease: what we know and what we don't know (but should). Proc Am Thorac Soc 2007;4:522-525 (Pubitemid 47547846)
    • (2007) Proceedings of the American Thoracic Society , vol.4 , Issue.7 , pp. 522-525
    • Agusti, A.1
  • 75
    • 0242720157 scopus 로고    scopus 로고
    • What do chronic obstructive pulmonary disease patients die from? a multiple cause coding analysis
    • DOI 10.1183/09031936.03.00031403
    • Hansell AL, Walk JA, Soriano JB. What do chronic obstructive pulmonary disease patients die from? A multiple cause coding analysis. Eur Respir J 2003;22:809-814 (Pubitemid 37369571)
    • (2003) European Respiratory Journal , vol.22 , Issue.5 , pp. 809-814
    • Hansell, A.L.1    Walk, J.A.2    Soriano, J.B.3
  • 77
    • 34247854749 scopus 로고    scopus 로고
    • Ascertainment of cause-specific mortality in COPD: Operations of the TORCH Clinical Endpoint Committee
    • DOI 10.1136/thx.2006.072348
    • McGarvey LP, John M, Anderson JA, et al. Ascertainment of cause-specific mortality in COPD - Operations of the TORCH Clinical Endpoint Committee. Thorax 2007;62:411-415 (Pubitemid 46698390)
    • (2007) Thorax , vol.62 , Issue.5 , pp. 411-415
    • McGarvey, L.P.1    John, M.2    Anderson, J.A.3    Zvarich, M.4    Wise, R.A.5
  • 78
    • 67649397850 scopus 로고    scopus 로고
    • Unifying the genetics, co-morbidities and management of COPD
    • DOI 10.1177/1753465808092282
    • Wood AM, Stockley RA. Unifying the genetics, co-morbidities and management of COPD. Ther Adv Respir Dis 2008;2:113-117 (Pubitemid 351818736)
    • (2008) Therapeutic Advances in Respiratory Disease , vol.2 , Issue.3 , pp. 113-117
    • Wood, A.M.1    Stockley, R.A.2
  • 79
    • 33747600439 scopus 로고    scopus 로고
    • Systemic inflammation in patients with COPD and pulmonary hypertension
    • DOI 10.1378/chest.130.2.326
    • Joppa P, Petrasova D, Stancak B, et al. Systemic inflammation in patients with COPD and pulmonary hypertension. Chest 2006;130:326-333 (Pubitemid 44266997)
    • (2006) Chest , vol.130 , Issue.2 , pp. 326-333
    • Joppa, P.1    Petrasova, D.2    Stancak, B.3    Tkacova, R.4
  • 82
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C-reactive protein levels: The pravastatin inflammation/CRP evaluation (PRINCE): A randomized trial and cohort study
    • Albert MA, Danielson E, Rafai N, et al. Effect of statin therapy on C-reactive protein levels: the Pravastatin Inflammation/CRP Evaluation (PRINCE): a randomized trial and cohort study. JAMA 2001;286:64-70 (Pubitemid 32606333)
    • (2001) Journal of the American Medical Association , vol.286 , Issue.1 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3    Ridker, P.M.4
  • 84
    • 33846931592 scopus 로고    scopus 로고
    • Statin use is associated with reduced mortality in COPD
    • DOI 10.1183/09031936.00106406
    • Søyseth V, Brekke PH, Smith P, et al. Statin use is associated with reduced mortality in COPD. Eur Respir J 2007;29:279-283 (Pubitemid 46237383)
    • (2007) European Respiratory Journal , vol.29 , Issue.2 , pp. 279-283
    • Soyseth, V.1    Brekke, P.H.2    Smith, P.3    Omland, T.4
  • 87
    • 1842552109 scopus 로고    scopus 로고
    • Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper
    • ATS/ERS committee members
    • Celli BR, MacNee W, ATS/ERS committee members. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004;23:932-946
    • (2004) Eur Respir J , vol.23 , pp. 932-946
    • Celli, B.R.1    MacNee, W.2
  • 89
    • 27744516443 scopus 로고    scopus 로고
    • Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers
    • Willemse BW, ten Hacken NH, Rutgers B, et al. Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers. Eur Respir J 2005;26:835-845
    • (2005) Eur Respir J , vol.26 , pp. 835-845
    • Willemse, B.W.1    Ten Hacken, N.H.2    Rutgers, B.3
  • 92
    • 4544250529 scopus 로고    scopus 로고
    • Smoking cessation improves both direct and indirect airway hyperresponsiveness in COPD
    • Willemse BW, ten Hacken NH, Rutgers B, et al. Smoking cessation improves both direct and indirect airway hyperresponsiveness in COPD. Eur Respir J 2004;24:391-396
    • (2004) Eur Respir J , vol.24 , pp. 391-396
    • Willemse, B.W.1    Ten Hacken, N.H.2    Rutgers, B.3
  • 93
    • 33845310307 scopus 로고    scopus 로고
    • Exercise and the inflammatory response in chronic obstructive pulmonary disease (COPD) - Does training confer anti-inflammatory properties in COPD?
    • Garrod R, Ansley P, Canavan J, et al. Exercise and the inflammatory response in chronic obstructive pulmonary disease (COPD) - does training confer anti-inflammatory properties in COPD? Med Hypotheses 2007;68:291-298
    • (2007) Med Hypotheses , vol.68 , pp. 291-298
    • Garrod, R.1    Ansley, P.2    Canavan, J.3
  • 94
    • 33750115861 scopus 로고    scopus 로고
    • Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease
    • CD001104
    • Appleton S, Poole P, Smith B, et al. Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2006;3:CD001104
    • (2006) Cochrane Database Syst Rev , vol.3
    • Appleton, S.1    Poole, P.2    Smith, B.3
  • 96
    • 33750029372 scopus 로고    scopus 로고
    • Tiotropium for stable chronic obstructive pulmonary disease: A meta-analysis
    • DOI 10.1136/thx.2006.063271
    • Barr RG, Bourbeau J, Camargo CA, et al. Tiotropium for stable chronic obstructive pulmonary disease: A meta-analysis. Thorax 2006;61:854-862 (Pubitemid 44570305)
    • (2006) Thorax , vol.61 , Issue.10 , pp. 854-862
    • Barr, R.G.1    Bourbeau, J.2    Camargo, C.A.3    Ram, F.S.F.4
  • 97
    • 33947420902 scopus 로고    scopus 로고
    • 1 decline in COPD patients randomized to inhaled corticosteroids or placebo
    • 1 decline in COPD patients randomized to inhaled corticosteroids or placebo. Chest 2007;131:682-689
    • (2007) Chest , vol.131 , pp. 682-689
    • Soriano, J.B.1    Sin, D.D.2    Zhang, X.3
  • 98
    • 0036063208 scopus 로고    scopus 로고
    • The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: A systematic review of randomized placebo-controlled trials
    • DOI 10.1016/S0002-9343(02)01143-9, PII S0002934302011439
    • Alsaeedi A, Sin DD, McAlister FA. The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials. Am J Med 2002;113:59-65 (Pubitemid 34775161)
    • (2002) American Journal of Medicine , vol.113 , Issue.1 , pp. 59-65
    • Alsaeedi, A.1    Sin, D.D.2    McAlister, F.A.3
  • 100
    • 0028318612 scopus 로고
    • In chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial
    • COMBIVENT Inhalation Aerosol Study Group
    • COMBIVENT Inhalation Aerosol Study GroupIn chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial. Chest 1994;105:1411-1419
    • (1994) Chest , vol.105 , pp. 1411-1419
  • 101
    • 0031783283 scopus 로고    scopus 로고
    • Inhalation by nebulization of albuterol-ipratropium combination (Dey combination) is superior to either agent alone in the treatment of chronic obstructive pulmonary disease
    • DOI 10.1159/000029295
    • Gross N, Tashkin D, Miller R, et al. Inhalation by nebulization of albuterol-ipratropium combination (Dey combination) is superior to either agent alone in the treatment of chronic obstructive pulmonary disease. Dey Combination Solution Study Group. Respiration 1998;65:354-362 (Pubitemid 28491270)
    • (1998) Respiration , vol.65 , Issue.5 , pp. 354-362
    • Gross, N.1    Tashkin, D.2    Miller, R.3    Oren, J.4    Coleman, W.5    Linberg, S.6
  • 102
    • 16344392540 scopus 로고    scopus 로고
    • Eficacia broncodilatadora de la asociacion de salmeterol y tiotropio en pacientes con EPOC
    • DOI 10.1157/13071583, 75.153
    • Baloira Villar A, Vilarino Pombo C. Bronchodilator efficacy of combined salmeterol and tiotropium in patients with chronic obstructive pulmonary disease. Arch Bronconeumol 2005;41:130-134 (Pubitemid 40469297)
    • (2005) Archivos de Bronconeumologia , vol.41 , Issue.3 , pp. 130-134
    • Baloira Villar, A.1    Vilarino Pombo, C.2
  • 104
    • 40949119305 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
    • DOI 10.1002/14651858.CD003794.pub3
    • Nannini LJ, Cates CJ, Lasserson TJ, et al. Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2007;4:CD003794 (Pubitemid 351805196)
    • (2007) Cochrane Database of Systematic Reviews , Issue.4
    • Nannini, L.J.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 105
    • 38449104740 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta-agonist in one inhaler versus long-acting beta-agonists for chronic obstructive pulmonary disease
    • DOI 10.1002/14651858.CD006829
    • Nannini LJ, Cates CJ, Lasserson TJ, et al. Combined corticosteroid and long-acting beta-agonist in one inhaler versus longacting beta-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2007;4:CD006829 (Pubitemid 351805194)
    • (2007) Cochrane Database of Systematic Reviews , Issue.4
    • Nannini, L.J.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 106
    • 38449087450 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease
    • DOI 10.1002/14651858.CD006826
    • Nannini LJ, Cates CJ, Lasserson TJ, et al. Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2007;4:CD006826 (Pubitemid 351805193)
    • (2007) Cochrane Database of Systematic Reviews , Issue.4
    • Nannini, L.J.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 107
    • 0037425745 scopus 로고    scopus 로고
    • Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: A randomised controlled trial
    • DOI 10.1016/S0140-6736(03)12459-2
    • Calverley P, Pauwels R, Vestbo J, et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2003;361:449-456 (Pubitemid 36173708)
    • (2003) Lancet , vol.361 , Issue.9356 , pp. 449-456
    • Calverley, P.1    Pauwels, R.2    Vestbo, J.3    Jones, P.4    Pride, N.5    Gulsvik, A.6    Anderson, J.7    Maden, C.8
  • 110
    • 48949103222 scopus 로고    scopus 로고
    • Effect of pharmacotherapy on rate of decline of lung function in COPD: Results from the TORCH study
    • Celli B, Thomas NE, Anderson JA, et al. Effect of pharmacotherapy on rate of decline of lung function in COPD: results from the TORCH study. Am J Respir Crit Care Med 2008;178:332-338
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 332-338
    • Celli, B.1    Thomas, N.E.2    Anderson, J.A.3
  • 111
    • 37549021118 scopus 로고    scopus 로고
    • The use of statins and lung function in current and former smokers
    • Keddissi JI, Younis WG, Chbeir EA, et al. The use of statins and lung function in current and former smokers. Chest 2007;132:1764-1771
    • (2007) Chest , vol.132 , pp. 1764-1771
    • Keddissi, J.I.1    Younis, W.G.2    Chbeir, E.A.3
  • 112
    • 33645304010 scopus 로고    scopus 로고
    • Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease
    • Barnes NC, Qiu YS, Pavord ID, et al. Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease. Am J Respir Crit Care Med 2006;173:736-743
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 736-743
    • Barnes, N.C.1    Qiu, Y.S.2    Pavord, I.D.3
  • 113
    • 36049046128 scopus 로고    scopus 로고
    • Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: A randomised controlled trial
    • DOI 10.1136/thx.2006.071068
    • Bourbeau J, Christodoulopoulos P, Maltais F, et al. Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomized controlled trial. Thorax 2007;62:938-943 (Pubitemid 350084490)
    • (2007) Thorax , vol.62 , Issue.11 , pp. 938-943
    • Bourbeau, J.1    Christodoulopoulos, P.2    Maltais, F.3    Yamauchi, Y.4    Olivenstein, R.5    Hamid, Q.6
  • 114
    • 4644230621 scopus 로고    scopus 로고
    • Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease
    • DOI 10.1164/rccm.200404-543OC
    • Sin DD, Lacy P, York E, et al. Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004;170:760-765 (Pubitemid 39298991)
    • (2004) American Journal of Respiratory and Critical Care Medicine , vol.170 , Issue.7 , pp. 760-765
    • Sin, D.D.1    Lacy, P.2    York, E.3    Man, S.F.P.4
  • 116
    • 33644763964 scopus 로고    scopus 로고
    • Corticosteroids and adrenoceptor agonists: The compliments for combination therapy in chronic airways diseases
    • DOI 10.1016/j.ejphar.2005.12.049, PII S0014299905013786, The Pharmacology of the Respiratory Tract
    • Sin DD, Man SF. Corticosteroids and adrenoceptor agonists: the compliments for combination therapy in chronic airways diseases. Eur J Pharmacol 2006;533:28-35 (Pubitemid 43340002)
    • (2006) European Journal of Pharmacology , vol.533 , Issue.1-3 , pp. 28-35
    • Sin, D.D.1    Man, S.F.P.2


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