-
1
-
-
84855166051
-
Facing a "slow-motion disaster" - The UN meeting on noncommunicable diseases
-
Rosenbaum L, Lamas D. Facing a "slow-motion disaster" - the UN meeting on noncommunicable diseases. N Engl J Med. 2011;365(25):2345-2348.
-
(2011)
N Engl J Med
, vol.365
, Issue.25
, pp. 2345-2348
-
-
Rosenbaum, L.1
Lamas, D.2
-
2
-
-
77957705828
-
Chronic obstructive pulmonary disease phenotypes: The future of COPD
-
Han MK, et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med. 2010;182(5):598-604.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, Issue.5
, pp. 598-604
-
-
Han, M.K.1
-
3
-
-
0035218679
-
Oxidants/antioxidants and chronic obstructive pulmonary disease: Pathogenesis to therapy
-
MacNee W. Oxidants/antioxidants and chronic obstructive pulmonary disease: pathogenesis to therapy. Novartis Found Symp. 2001;234:169-185.
-
(2001)
Novartis Found Symp
, vol.234
, pp. 169-185
-
-
MacNee, W.1
-
4
-
-
0028856840
-
Dietary antioxidants and cigarette smoke-induced biomolecular damage: A complex interaction
-
Eiserich JP, van der Vliet A, Handelman GJ, Halliwell B, Cross CE. Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. Am J Clin Nutr. 1995;62(6 suppl):1490S-1500S.
-
(1995)
Am J Clin Nutr
, vol.62
, Issue.6 SUPPL.
-
-
Eiserich, J.P.1
Van Der Vliet, A.2
Handelman, G.J.3
Halliwell, B.4
Cross, C.E.5
-
5
-
-
0024438957
-
The effect of cigarette smoking on neutrophil kinetics in human lungs
-
MacNee W, Wiggs B, Belzberg AS, Hogg JC. The effect of cigarette smoking on neutrophil kinetics in human lungs. N Engl J Med. 1989;321(14):924-928. (Pubitemid 19244050)
-
(1989)
New England Journal of Medicine
, vol.321
, Issue.14
, pp. 924-928
-
-
MacNee, W.1
Wiggs, B.2
Belzberg, A.S.3
Hogg, J.C.4
-
6
-
-
77954470662
-
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smokeinduced pulmonary injury and emphysema
-
Yoshida T, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smokeinduced pulmonary injury and emphysema. Nat Med. 2010;16(7):767-773.
-
(2010)
Nat Med
, vol.16
, Issue.7
, pp. 767-773
-
-
Yoshida, T.1
-
7
-
-
82855181155
-
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: Role of oxidative stress and ceramides
-
Schweitzer KS, et al. Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. Am J Physiol Lung Cell Mol Physiol. 2011;301(6):L836-L846.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
, Issue.6
-
-
Schweitzer, K.S.1
-
8
-
-
80052478316
-
Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact
-
Presson RG Jr, et al. Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. Am J Pathol. 2011;179(1):75-82.
-
(2011)
Am J Pathol
, vol.179
, Issue.1
, pp. 75-82
-
-
Presson Jr., R.G.1
-
9
-
-
33750620057
-
Oxidative stress and redox regulation of lung inflammation in COPD
-
DOI 10.1183/09031936.06.00053805
-
Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J. 2006;28(1):219-242. (Pubitemid 44914279)
-
(2006)
European Respiratory Journal
, vol.28
, Issue.1
, pp. 219-242
-
-
Rahman, I.1
Adcock, I.M.2
-
10
-
-
34447556991
-
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
-
DOI 10.1152/physrev.00048.2006
-
Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev. 2007;87(3):1047-1082. (Pubitemid 47084676)
-
(2007)
Physiological Reviews
, vol.87
, Issue.3
, pp. 1047-1082
-
-
Yoshida, T.1
Tuder, R.M.2
-
11
-
-
74949088495
-
Targeted disruption of NF-{kappa} B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: A critical role of p50 in chromatin remodeling
-
Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I. Targeted disruption of NF-{kappa} B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol. 2010;298(2):L197-L209.
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.298
, Issue.2
-
-
Rajendrasozhan, S.1
Chung, S.2
Sundar, I.K.3
Yao, H.4
Rahman, I.5
-
12
-
-
80054696408
-
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice
-
Seimetz M, et al. Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice. Cell. 2011;147(2):293-305.
-
(2011)
Cell
, vol.147
, Issue.2
, pp. 293-305
-
-
Seimetz, M.1
-
13
-
-
33644828187
-
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
-
DOI 10.1038/nm1361, PII N1361
-
Weathington NM, et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med. 2006;12(3):317-323. (Pubitemid 43355080)
-
(2006)
Nature Medicine
, vol.12
, Issue.3
, pp. 317-323
-
-
Weathington, N.M.1
Van Houwelingen, A.H.2
Noerager, B.D.3
Jackson, P.L.4
Kraneveld, A.D.5
Galin, F.S.6
Folkerts, G.7
Nijkamp, F.P.8
Blalock, J.E.9
-
14
-
-
43049083361
-
Cells, mediators and Toll-like receptors in COPD
-
Sarir H, Henricks PAJ, van Houwelingen AH, Nijkamp FP, Folkerts G. Cells, mediators and Toll-like receptors in COPD. Eur J Pharmacol. 2008;585(2-3):346-353.
-
(2008)
Eur J Pharmacol
, vol.585
, Issue.2-3
, pp. 346-353
-
-
Sarir, H.1
Henricks, P.A.J.2
Van Houwelingen, A.H.3
Nijkamp, F.P.4
Folkerts, G.5
-
15
-
-
33750580556
-
Toll-like receptor 4 deficiency causes pulmonary emphysema
-
DOI 10.1172/JCI28139
-
Zhang X, Shan P, Jiang G, Cohn L, Lee PJ. Toll-like receptor 4 deficiency causes pulmonary emphysema. J Clin Invest. 2006;116(11):3050-3059. (Pubitemid 44684490)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3050-3059
-
-
Zhang, X.1
Shan, P.2
Jiang, G.3
Cohn, L.4
Lee, P.J.5
-
16
-
-
0036863624
-
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
-
DOI 10.1016/S1097-2765(02)00706-2
-
Ellisen LW, et al. REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol Cell. 2002;10(5):995-1005. (Pubitemid 35453821)
-
(2002)
Molecular Cell
, vol.10
, Issue.5
, pp. 995-1005
-
-
Ellisen, L.W.1
Ramsayer, K.D.2
Johannessen, C.M.3
Yang, A.4
Beppu, H.5
Minda, K.6
Oliner, J.D.7
McKeon, F.8
Haber, D.A.9
-
17
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis
-
DOI 10.1128/MCB.22.7.2283-2293.2002
-
Shoshani T, et al. Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol. 2002;22(7):2283-2293. (Pubitemid 34224633)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
Kalinski, H.11
Kamer, I.12
Rozen, A.13
Mor, O.14
Keshet, E.15
Leshkowitz, D.16
Einat, P.17
Skaliter, R.18
Feinstein, E.19
-
18
-
-
10044276783
-
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
-
DOI 10.1101/gad.1256804
-
Brugarolas J, et al. Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev. 2004;18(23):2893-2904. (Pubitemid 39602308)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2893-2904
-
-
Brugarolas, J.1
Lei, K.2
Hurley, R.L.3
Manning, B.D.4
Reiling, J.H.5
Hafen, E.6
Witters, L.A.7
Ellisen, L.W.8
Kaelin Jr., W.G.9
-
19
-
-
77957237159
-
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
-
Malhotra D, et al. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res. 2010;38(17):5718-5734.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.17
, pp. 5718-5734
-
-
Malhotra, D.1
-
20
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
DOI 10.1172/JCI200421146
-
Rangasamy T, et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest. 2004;114(9):1248-1259. (Pubitemid 40385296)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
21
-
-
0013828812
-
Studies in alpha-1-atitrypsin
-
Eriksson S. Studies in alpha-1-atitrypsin. Acta Med Scand Suppl. 1965;432:1-85.
-
(1965)
Acta Med Scand Suppl
, vol.432
, pp. 1-85
-
-
Eriksson, S.1
-
22
-
-
0017127862
-
The induction of emphysema with elastase. II. Changes in connective tissue
-
Kuhn C, Yu SY, Chraplyvy M, Linder HE, Senior RM. The induction of emphysema with elastase. II. Changes in connective tissue. Lab Invest. 1976;34(4):372-380.
-
(1976)
Lab Invest
, vol.34
, Issue.4
, pp. 372-380
-
-
Kuhn, C.1
Yu, S.Y.2
Chraplyvy, M.3
Linder, H.E.4
Senior, R.M.5
-
23
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
DOI 10.1126/science.277.5334.2002
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science. 1997;277(5334):2002-2004. (Pubitemid 27449144)
-
(1997)
Science
, vol.277
, Issue.5334
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
24
-
-
0041740002
-
Pathobiology of chronic bronchitis and emphysema
-
Voelkel NF, MacNee W, eds. Hamilton, Ontario, Canada: BC Decker Inc.
-
Tuder RM, Voelkel NF. Pathobiology of chronic bronchitis and emphysema. In: Voelkel NF, MacNee W, eds. Chronic Obstructive Lung Disease. Hamilton, Ontario, Canada: BC Decker Inc.; 2001:63-76.
-
(2001)
Chronic Obstructive Lung Disease
, pp. 63-76
-
-
Tuder, R.M.1
Voelkel, N.F.2
-
26
-
-
0037348961
-
The pathobiological mechanisms of emphysema models: What do they have in common?
-
DOI 10.1016/S1094-5539(02)00099-8
-
Tuder RM, McGrath S, Neptune E. The pathobiological mechanisms of emphysema models: what do they have in common? Pulm Pharmacol Ther. 2003;16(2):67-78. (Pubitemid 36369397)
-
(2003)
Pulmonary Pharmacology and Therapeutics
, vol.16
, Issue.2
, pp. 67-78
-
-
Tuder, R.M.1
McGrath, S.2
Neptune, E.3
-
27
-
-
0033660171
-
Inhibition of vascular endothelial growth factor receptors causes lung cell apoptosis and emphysema
-
Kasahara Y, et al. Inhibition of vascular endothelial growth factor receptors causes lung cell apoptosis and emphysema. J Clin Invest. 2000;106(11):1311-1319.
-
(2000)
J Clin Invest
, vol.106
, Issue.11
, pp. 1311-1319
-
-
Kasahara, Y.1
-
28
-
-
79952731002
-
Regenerative pathways and emphysema: A new paradigm?
-
Lam AP, Gottardi CJ, Tuder R. Regenerative pathways and emphysema: a new paradigm? Am J Respir Crit Care Med. 2011;183(6):688-690.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, Issue.6
, pp. 688-690
-
-
Lam, A.P.1
Gottardi, C.J.2
Tuder, R.3
-
29
-
-
79955519064
-
Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: Implications for therapy
-
Nakanishi K, et al. Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy. Am J Respir Crit Care Med. 2011;183(9):1164-1175.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, Issue.9
, pp. 1164-1175
-
-
Nakanishi, K.1
-
30
-
-
84862833566
-
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
-
McDonough JE, et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med. 2011;365(17):1567-1575.
-
(2011)
N Engl J Med
, vol.365
, Issue.17
, pp. 1567-1575
-
-
McDonough, J.E.1
-
31
-
-
0038070232
-
Apoptosis and emphysema: The missing link
-
DOI 10.1165/rcmb.F269
-
Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. Am J Resp Cell Mol Biol. 2003;28(5):551-554. (Pubitemid 36543401)
-
(2003)
American Journal of Respiratory Cell and Molecular Biology
, vol.28
, Issue.5
, pp. 551-554
-
-
Tuder, R.M.1
Petrache, I.2
Elias, J.A.3
Voelkel, N.F.4
Henson, P.M.5
-
32
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med. 2001;163(3 pt 1):737-744. (Pubitemid 32230838)
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.163
, Issue.3 I
, pp. 737-744
-
-
Kasahara, Y.1
Tuder, R.M.2
Cool, C.D.3
Lynch, D.A.4
Flores, S.C.5
Voelkel, N.F.6
-
33
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
DOI 10.1038/nm1238
-
Petrache I, et al. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med. 2005;11(5):491-498. (Pubitemid 40685971)
-
(2005)
Nature Medicine
, vol.11
, Issue.5
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
Cho, C.6
Hubbard, W.C.7
Berdyshev, E.V.8
Tuder, R.M.9
-
35
-
-
49049112707
-
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
-
Petrache I, et al. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol. 2008;295(1):L44-L53.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
, Issue.1
-
-
Petrache, I.1
-
36
-
-
79957880378
-
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smokeinduced emphysema in mice
-
Clauss M, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smokeinduced emphysema in mice. J Clin Invest. 2011;121(6):2470-2479.
-
(2011)
J Clin Invest
, vol.121
, Issue.6
, pp. 2470-2479
-
-
Clauss, M.1
-
37
-
-
69249216689
-
Combinatorial ligand-directed lung targeting
-
Giordano RJ, Edwards JK, Tuder RM, Arap W, Pasqualini R. Combinatorial ligand-directed lung targeting. Proc Am Thorac Soc. 2009;6(5):411-415.
-
(2009)
Proc Am Thorac Soc
, vol.6
, Issue.5
, pp. 411-415
-
-
Giordano, R.J.1
Edwards, J.K.2
Tuder, R.M.3
Arap, W.4
Pasqualini, R.5
-
38
-
-
72549115279
-
Heightened endoplasmic reticulum stress in COPD lungs: The role of Nrf2-regulated proteasomal activity
-
Malhotra D, et al. Heightened endoplasmic reticulum stress in COPD lungs: The role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med. 2009;180(12):1196-1207.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, Issue.12
, pp. 1196-1207
-
-
Malhotra, D.1
-
39
-
-
64749097430
-
Oxidative damage to nucleic acids in severe emphysema
-
Deslee G, et al. Oxidative damage to nucleic acids in severe emphysema. Chest. 2009;135(4):965-974.
-
(2009)
Chest
, vol.135
, Issue.4
, pp. 965-974
-
-
Deslee, G.1
-
40
-
-
78149476302
-
Identification of an autophagy defect in smokers' alveolar macrophages
-
Monick MM, et al. Identification of an autophagy defect in smokers' alveolar macrophages. J Immunol. 2010;185(9):5425-5435.
-
(2010)
J Immunol
, vol.185
, Issue.9
, pp. 5425-5435
-
-
Monick, M.M.1
-
41
-
-
78650057959
-
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages
-
Petrusca DN, et al. Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem. 2010;285(51):40322-40332.
-
(2010)
J Biol Chem
, vol.285
, Issue.51
, pp. 40322-40332
-
-
Petrusca, D.N.1
-
42
-
-
2942729796
-
Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity
-
Monick MM, et al. Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. J Immunol. 2004;173(1):123-135. (Pubitemid 38797333)
-
(2004)
Journal of Immunology
, vol.173
, Issue.1
, pp. 123-135
-
-
Monick, M.M.1
Mallampalli, R.K.2
Bradford, M.3
McCoy, D.4
Gross, T.J.5
Flaherty, D.M.6
Powers, L.S.7
Cameron, K.8
Kelly, S.9
Merrill Jr., A.H.10
Hunninghake, G.W.11
-
43
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS ONE. 2008;3(10):e3316.
-
(2008)
PLoS ONE
, vol.3
, Issue.10
-
-
Chen, Z.H.1
-
44
-
-
80052895371
-
Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells
-
Csordas A, et al. Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells. Cardiovasc Res. 2011;92(1):141-148.
-
(2011)
Cardiovasc Res
, vol.92
, Issue.1
, pp. 141-148
-
-
Csordas, A.1
-
45
-
-
77954623119
-
Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD
-
Hwang JW, et al. Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys. 2010;500(2):203-209.
-
(2010)
Arch Biochem Biophys
, vol.500
, Issue.2
, pp. 203-209
-
-
Hwang, J.W.1
-
46
-
-
53549090696
-
Autophagic proteins regulate cigarette smoke-induced apoptosis: Protective role of heme oxygenase-1
-
Kim HP, et al. Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy. 2008;4(7):887-895.
-
(2008)
Autophagy
, vol.4
, Issue.7
, pp. 887-895
-
-
Kim, H.P.1
-
47
-
-
32544436757
-
Why does airway inflammation persist after the smoking stops?
-
DOI 10.1136/thx.2005.049502
-
Hogg JC. Why does airway inflammation persist after the smoking stops? Thorax. 2006;61(2):96-97. (Pubitemid 43235422)
-
(2006)
Thorax
, vol.61
, Issue.2
, pp. 96-97
-
-
Hogg, J.C.1
-
48
-
-
79952227062
-
Neutral sphingomyelinase 2: A novel target in cigarette smoke-induced apoptosis and lung injury
-
Filosto S, et al. Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. Am J Respir Cell Mol Biol. 2011;44(3):350-360.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, Issue.3
, pp. 350-360
-
-
Filosto, S.1
-
49
-
-
20444368841
-
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-γ-induced alveolar remodeling and pulmonary emphysema
-
Zheng T, et al. Role of cathepsin S-dependent epithelial cell apoptosis in IFN-γ-induced alveolar remodeling and pulmonary emphysema. J Immunol. 2005;174(12):8106-8115. (Pubitemid 40806322)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 8106-8115
-
-
Zheng, T.1
Kang, M.J.2
Crothers, K.3
Zhu, Z.4
Liu, W.5
Lee, C.G.6
Rabach, L.A.7
Chapman, H.A.8
Homer, R.J.9
Aldous, D.10
DeSanctis, G.11
Underwood, S.12
Graupe, M.13
Flavell, R.A.14
Schmidt, J.A.15
Elias, J.A.16
-
50
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
DOI 10.1165/rcmb.2002-0228OC
-
Tuder RM, et al. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol. 2003;29(1):88-97. (Pubitemid 36783320)
-
(2003)
American Journal of Respiratory Cell and Molecular Biology
, vol.29
, Issue.1
, pp. 88-97
-
-
Tuder, R.M.1
Zhen, L.2
Cho, C.Y.3
Taraseviciene-Stewart, L.4
Kasahara, Y.5
Salvemini, D.6
Voelkel, N.F.7
Flores, S.C.8
-
51
-
-
66249127897
-
Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA
-
Richens TR, et al. Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA. Am J Respir Crit Care Med. 2009;179(11):1011-1021.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, Issue.11
, pp. 1011-1021
-
-
Richens, T.R.1
-
52
-
-
66649127821
-
Immunologic aspects of chronic obstructive pulmonary disease
-
Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med. 2009;360(23):2445-2454.
-
(2009)
N Engl J Med
, vol.360
, Issue.23
, pp. 2445-2454
-
-
Cosio, M.G.1
Saetta, M.2
Agusti, A.3
-
54
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
DOI 10.1056/NEJMoa041892
-
Ito K, et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med. 2005;352(19):1967-1976. (Pubitemid 40638367)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.19
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
Cosio, B.4
Caramori, G.5
Onn, M.K.6
Barczyk, A.7
Hayashi, S.8
Adcock, I.M.9
Hogg, J.C.10
Barnes, P.J.11
-
55
-
-
42649146208
-
SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
-
DOI 10.1164/rccm.200708-1269OC
-
Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177(8):861-870. (Pubitemid 351600664)
-
(2008)
American Journal of Respiratory and Critical Care Medicine
, vol.177
, Issue.8
, pp. 861-870
-
-
Rajendrasozhan, S.1
Yang, S.-R.2
Kinnula, V.L.3
Rahman, I.4
-
56
-
-
70149110900
-
Smoking-dependent reprogramming of alveolar macrophage polarization: Implication for pathogenesis of chronic obstructive pulmonary disease
-
Shaykhiev R, et al. Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J Immunol. 2009;183(4):2867-2883.
-
(2009)
J Immunol
, vol.183
, Issue.4
, pp. 2867-2883
-
-
Shaykhiev, R.1
-
57
-
-
0034949094
-
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
-
DOI 10.1183/09031936.01.17509460
-
Majo J, Ghezzo H, Cosio MG. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J. 2001;17(5):946-953. (Pubitemid 32600344)
-
(2001)
European Respiratory Journal
, vol.17
, Issue.5
, pp. 946-953
-
-
Majo, J.1
Ghezzo, H.2
Cosio, M.G.3
-
58
-
-
24144433461
-
+ T cells in the lungs of patients with severe emphysema
-
DOI 10.1164/rccm.200410-1332OC
-
Sullivan AK, et al. Oligoclonal CD4+ T cells in the lungs of patients with severe emphysema. Am J Respir Crit Care Med. 2005;172(5):590-596. (Pubitemid 41232970)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.172
, Issue.5
, pp. 590-596
-
-
Sullivan, A.K.1
Simonian, P.L.2
Falta, M.T.3
Mitchell, J.D.4
Cosgrove, G.P.5
Brown, K.K.6
Kotzin, B.L.7
Voelkel, N.F.8
Fontenot, A.P.9
-
59
-
-
65649102628
-
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease
-
Borchers MT, et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J Clin Invest. 2009;119(3):636-649.
-
(2009)
J Clin Invest
, vol.119
, Issue.3
, pp. 636-649
-
-
Borchers, M.T.1
-
60
-
-
51849129227
-
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of Its positive regulator, DJ-1
-
Malhotra D, et al. Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of Its positive regulator, DJ-1. Am J Respir Crit Care Med. 2008;178(6):592-604.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, Issue.6
, pp. 592-604
-
-
Malhotra, D.1
-
61
-
-
79954542852
-
Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model
-
Harvey CJ, et al. Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model. Sci Transl Med. 2011;3(78):78ra32.
-
(2011)
Sci Transl Med
, vol.3
, Issue.78
-
-
Harvey, C.J.1
-
62
-
-
48749097634
-
Cigarette smoke selectively enhances viral PAMP and viruses-induced pulmonary innate immunity and remodeling responses
-
Kang MJ, et al. Cigarette smoke selectively enhances viral PAMP and viruses-induced pulmonary innate immunity and remodeling responses. J Clin Invest. 2008;118(8):2771-2784.
-
(2008)
J Clin Invest
, vol.118
, Issue.8
, pp. 2771-2784
-
-
Kang, M.J.1
-
63
-
-
77952307233
-
Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
-
Ferhani N, et al. Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010;181(9):917-927.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.9
, pp. 917-927
-
-
Ferhani, N.1
-
64
-
-
33644643244
-
Elastin fragments drive disease progression in a murine model of emphysema
-
DOI 10.1172/JCI25617
-
Houghton AM, et al. Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest. 2006;116(3):753-759. (Pubitemid 43326884)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 753-759
-
-
Houghton, A.M.1
Quintero, P.A.2
Perkins, D.L.3
Kobayashi, D.K.4
Kelley, D.G.5
Marconcini, L.A.6
Mecham, R.P.7
Senior, R.M.8
Shapiro, S.D.9
-
65
-
-
10444263068
-
Peripheral lung remodelling in asthma and chronic obstructive pulmonary disease
-
DOI 10.1183/09031936.04.00110704
-
Hogg J. Peripheral lung remodelling in asthma and chronic obstructive pulmonary disease. Eur Respir J. 2004;24(6):893-894. (Pubitemid 39642273)
-
(2004)
European Respiratory Journal
, vol.24
, Issue.6
, pp. 893-894
-
-
Hogg, J.1
-
66
-
-
33646540731
-
Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers
-
DOI 10.1164/rccm.200508-1330OC
-
Cantin AM, et al. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med. 2006;173(10):1139-1144. (Pubitemid 43726895)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.10
, pp. 1139-1144
-
-
Cantin, A.M.1
Hanrahan, J.W.2
Bilodeau, G.3
Ellis, L.4
Dupuis, A.5
Liao, J.6
Zielenski, J.7
Durie, P.8
-
67
-
-
80655125176
-
Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease
-
Lee CG, et al. Studies of vascular endothelial growth factor in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2011;8(6):512-515.
-
(2011)
Proc Am Thorac Soc
, vol.8
, Issue.6
, pp. 512-515
-
-
Lee, C.G.1
-
69
-
-
84855441194
-
Angiotensin receptor blockade attenuates cigarette smoke induced lung injury and rescues lung architecture in a murine model
-
Podowski M, et al. Angiotensin receptor blockade attenuates cigarette smoke induced lung injury and rescues lung architecture in a murine model. J Clin Invest. 2011;122(1):229-240.
-
(2011)
J Clin Invest
, vol.122
, Issue.1
, pp. 229-240
-
-
Podowski, M.1
-
70
-
-
63349099346
-
The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling
-
Churg A, Zhou S, Wang X, Wang R, Wright JL. The role of interleukin-1beta in murine cigarette smoke-induced emphysema and small airway remodeling. Am J Respir Cell Mol Biol. 2009;40(4):482-490.
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, Issue.4
, pp. 482-490
-
-
Churg, A.1
Zhou, S.2
Wang, X.3
Wang, R.4
Wright, J.L.5
-
71
-
-
13844266182
-
Correlation of lung surface area to apoptosis and proliferation in human emphysema
-
DOI 10.1183/09031936.05.00023704
-
Imai K, Mercer BA, Schulman LL, Sonett JR, D'Armiento JM. Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J. 2005;25(2):250-258. (Pubitemid 40246524)
-
(2005)
European Respiratory Journal
, vol.25
, Issue.2
, pp. 250-258
-
-
Imai, K.1
Mercer, B.A.2
Schulman, L.L.3
Sonett, J.R.4
D'Armiento, J.M.5
-
72
-
-
0038506712
-
Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha-converting enzyme and amphiregulin
-
DOI 10.1074/jbc.M207018200
-
Lemjabbar H, Li D, Gallup M, Sidhu S, Drori E, Basbaum C. Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha-converting enzyme and amphiregulin. J Biol Chem. 2003;278(28):26202-26207. (Pubitemid 36835389)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.28
, pp. 26202-26207
-
-
Lemjabbar, H.1
Li, D.2
Gallup, M.3
Sidhu, S.4
Drori, E.5
Basbaum, C.6
-
73
-
-
73649112422
-
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation
-
Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell. 2010;17(1):89-97.
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 89-97
-
-
Takahashi, H.1
Ogata, H.2
Nishigaki, R.3
Broide, D.H.4
Karin, M.5
-
74
-
-
64749083599
-
Lung cancer and chronic obstructive pulmonary disease: Needs and opportunities for integrated research
-
Punturieri A, Szabo E, Croxton TL, Shapiro SD, Dubinett SM. Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. J Natl Cancer Inst. 2009;101(8):554-559.
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.8
, pp. 554-559
-
-
Punturieri, A.1
Szabo, E.2
Croxton, T.L.3
Shapiro, S.D.4
Dubinett, S.M.5
-
75
-
-
33947525131
-
Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress
-
DOI 10.1254/jphs.FP0061055
-
Yamaguchi Y, Nasu F, Harada A, Kunitomo M. Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress. J Pharmacol Sci. 2007;103(3):275-282. (Pubitemid 46465770)
-
(2007)
Journal of Pharmacological Sciences
, vol.103
, Issue.3
, pp. 275-282
-
-
Yamaguchi, Y.1
Nasu, F.2
Harada, A.3
Kunitomo, M.4
-
76
-
-
58549105575
-
Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
-
Sussan TE, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci U S A. 2009;106(1):250-255.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.1
, pp. 250-255
-
-
Sussan, T.E.1
-
77
-
-
0036212004
-
Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD
-
DOI 10.1183/09031936.02.00245902
-
Santos S, et al. Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD. Eur Respir J. 2002;19(4):632-638. (Pubitemid 34285159)
-
(2002)
European Respiratory Journal
, vol.19
, Issue.4
, pp. 632-638
-
-
Santos, S.1
Peinado, V.I.2
Ramirez, J.3
Melgosa, T.4
Roca, J.5
Rodriguez-Roisin, R.6
Barbera, J.A.7
-
78
-
-
45149117722
-
Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: Analysis using guinea pig precision cut lung slices
-
Wright JL, Churg A. Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: analysis using guinea pig precision cut lung slices. J Appl Physiol. 2008;104(5):1462-1469.
-
(2008)
J Appl Physiol
, vol.104
, Issue.5
, pp. 1462-1469
-
-
Wright, J.L.1
Churg, A.2
-
79
-
-
77958464493
-
Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking
-
Schweitzer KS, et al. Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking. Am J Respir Crit Care Med. 2011;183(2):215-225.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, Issue.2
, pp. 215-225
-
-
Schweitzer, K.S.1
-
80
-
-
33644856620
-
Circulating haemopoietic and endothelial progenitor cells are decreased in COPD
-
DOI 10.1183/09031936.06.00120604
-
Palange P, et al. Circulating haemopoietic and endothelial progenitor cells are decreased in COPD. Eur Respir J. 2006;27(3):529-541. (Pubitemid 43372527)
-
(2006)
European Respiratory Journal
, vol.27
, Issue.3
, pp. 529-541
-
-
Palange, P.1
Testa, U.2
Huertas, A.3
Calabro, L.4
Antonucci, R.5
Petrucci, E.6
Pelosi, E.7
Pasquini, L.8
Satta, A.9
Morici, G.10
Vignola, M.A.11
Bonsignore, M.R.12
-
81
-
-
0037102380
-
Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease
-
Agusti AG, et al. Skeletal muscle apoptosis and weight loss in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2002;166(4):485-489.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, Issue.4
, pp. 485-489
-
-
Agusti, A.G.1
-
82
-
-
33845455679
-
Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation
-
DOI 10.1165/rcmb.2006-0103OC
-
Langen RC, Schols AM, Kelders MC, van der Velden JL, Wouters EF, Janssen-Heininger YM. Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation. Am J Respir Cell Mol Biol. 2006;35(6):689-696. (Pubitemid 44901858)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.35
, Issue.6
, pp. 689-696
-
-
Langen, R.C.J.1
Schols, A.M.W.J.2
Kelders, M.C.J.M.3
Van Der, V.J.L.J.4
Wouters, E.F.M.5
Janssen-Heininger, Y.M.W.6
-
83
-
-
27744516443
-
Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers
-
DOI 10.1183/09031936.05.00108904
-
Willemse BW, ten Hacken NH, Rutgers B, Lesman-Leegte IG, Postma DS, Timens W. Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers. Eur Respir J. 2005;26(5):835-845. (Pubitemid 41632040)
-
(2005)
European Respiratory Journal
, vol.26
, Issue.5
, pp. 835-845
-
-
Willemse, B.W.M.1
Ten, H.N.H.T.2
Rutgers, B.3
Lesman-Leegte, I.G.A.T.4
Postma, D.S.5
Timens, W.6
-
84
-
-
77249094660
-
Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines
-
Moriyama C, et al. Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines. Am J Respir Cell Mol Biol. 2010;42(3):304-311.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, Issue.3
, pp. 304-311
-
-
Moriyama, C.1
-
85
-
-
33747833375
-
Cellular and molecular mechanisms of alveolar destruction in emphysema: An evolutionary perspective
-
DOI 10.1513/pats.200603-054MS
-
Tuder RM, Yoshida T, Arap W, Pasqualini R, Petrache I. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective. Proc Am Thorac Soc. 2006;3(6):503-510. (Pubitemid 44285536)
-
(2006)
Proceedings of the American Thoracic Society
, vol.3
, Issue.6
, pp. 503-510
-
-
Tuder, R.M.1
Yoshida, T.2
Arap, W.3
Pasqualini, R.4
Petrache, I.5
-
86
-
-
79952218099
-
P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema
-
Lucattelli M, et al. P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema. Am J Respir Cell Mol Biol. 2011;44(3):423-429.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, Issue.3
, pp. 423-429
-
-
Lucattelli, M.1
-
87
-
-
80052482830
-
P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke
-
Eltom S, et al. P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke. PLoS One. 2011;6(9):e24097.
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Eltom, S.1
-
88
-
-
71849094775
-
Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema
-
Motz GT, et al. Persistence of lung CD8 T cell oligoclonal expansions upon smoking cessation in a mouse model of cigarette smoke-induced emphysema. J Immunol. 2008;181(11):8036-8043.
-
(2008)
J Immunol
, vol.181
, Issue.11
, pp. 8036-8043
-
-
Motz, G.T.1
-
89
-
-
38349070654
-
Autoantibodies in patients with chronic obstructive pulmonary disease
-
Feghali-Bostwick CA, et al. Autoantibodies in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008;177(2):156-163.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, Issue.2
, pp. 156-163
-
-
Feghali-Bostwick, C.A.1
-
90
-
-
80053428842
-
Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease
-
Kirkham PA, et al. Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011;184(7):796-802.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, Issue.7
, pp. 796-802
-
-
Kirkham, P.A.1
-
91
-
-
78649956146
-
Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice
-
Brandsma CA, et al. Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice. BMC Pulm Med. 2010;10:64.
-
(2010)
BMC Pulm Med
, vol.10
, pp. 64
-
-
Brandsma, C.A.1
-
92
-
-
16344378429
-
An animal model of autoimmune emphysema
-
DOI 10.1164/rccm.200409-1275OC
-
Taraseviciene-Stewart L, et al. An animal model of autoimmune emphysema. Am J Respir Crit Care Med. 2005;171(7):734-742. (Pubitemid 40471144)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.7
, pp. 734-742
-
-
Taraseviciene-Stewart, L.1
Scerbavicius, R.2
Choe, K.-H.3
Moore, M.4
Sullivan, A.5
Nicolls, M.R.6
Fontenot, A.P.7
Tuder, R.M.8
Voelkel, N.F.9
-
93
-
-
34249652351
-
Antielastin autoimmunity in tobacco smoking-induced emphysema
-
Lee SH, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med. 2007;13(5):567-569.
-
(2007)
Nat Med
, vol.13
, Issue.5
, pp. 567-569
-
-
Lee, S.H.1
-
94
-
-
0033406743
-
Cellular and connective tissue changes in alveolar septal walls in emphysema
-
Vlahovic G, Russell ML, Mercer RR, Crapo JD. Cellular and connective tissue changes in alveolar septal walls in emphysema. Am J Respir Crit Care Med. 1999;160(6):2086-2092. (Pubitemid 30004723)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.160
, Issue.6
, pp. 2086-2092
-
-
Vlahovic, G.1
Russell, M.L.2
Mercer, R.R.3
Crapo, J.D.4
-
95
-
-
77954664861
-
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema
-
Shan M, et al. Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med. 2009;1(4):4ra10.
-
(2009)
Sci Transl Med
, vol.1
, Issue.4
-
-
Shan, M.1
-
96
-
-
79957613753
-
IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke
-
Chen K, et al. IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS One. 2011;6(5):e20333.
-
(2011)
PLoS One
, vol.6
, Issue.5
-
-
Chen, K.1
-
98
-
-
80053502247
-
Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences
-
Pastukh VM, et al. Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences. Int J Chron Obstruct Pulmon Dis. 2011;6:209-217.
-
(2011)
Int J Chron Obstruct Pulmon Dis
, vol.6
, pp. 209-217
-
-
Pastukh, V.M.1
-
99
-
-
0037102347
-
4-Hydroxy-2-Nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease
-
Rahman I, et al. 4-Hydroxy-2-Nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2002;166(4):490-495.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, Issue.4
, pp. 490-495
-
-
Rahman, I.1
-
100
-
-
33644861968
-
Telomere shortening in smokers with and without COPD
-
DOI 10.1183/09031936.06.00087005
-
Morla M, Busquets X, Pons J, Sauleda J, MacNee W, Agusti AG. Telomere shortening in smokers with and without COPD. Eur Respir J. 2006;27(3):525-528. (Pubitemid 43372526)
-
(2006)
European Respiratory Journal
, vol.27
, Issue.3
, pp. 525-528
-
-
Morla, M.1
Busquets, X.2
Pons, J.3
Sauleda, J.4
MacNee, W.5
Agusti, A.G.N.6
-
101
-
-
65249172518
-
Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease
-
Savale L, et al. Shortened telomeres in circulating leukocytes of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009;179(7):566-571.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, Issue.7
, pp. 566-571
-
-
Savale, L.1
-
102
-
-
80054715764
-
Telomere length is a determinant of emphysema susceptibility
-
Alder JK, et al. Telomere length is a determinant of emphysema susceptibility. Am J Respir Crit Care Med. 2011;184(8):904-912.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, Issue.8
, pp. 904-912
-
-
Alder, J.K.1
-
103
-
-
80052435472
-
Current controversies and future perspectives in chronic obstructive pulmonary disease
-
Agusti A, Vestbo J. Current controversies and future perspectives in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011;184(5):507-513.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, Issue.5
, pp. 507-513
-
-
Agusti, A.1
Vestbo, J.2
-
104
-
-
76149139431
-
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
-
Diab KJ, et al. Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. Am J Respir Crit Care Med. 2010;181(4):344-352.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, Issue.4
, pp. 344-352
-
-
Diab, K.J.1
-
105
-
-
16944366965
-
Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
-
DOI 10.1038/nm0697-675
-
Massaro GD, Massaro D. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med. 1997;3(6):675-677. (Pubitemid 27264979)
-
(1997)
Nature Medicine
, vol.3
, Issue.6
, pp. 675-677
-
-
De Carlo, M.G.1
Massaro, D.2
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