Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 1, 2013, Pages 156-164

  Davidovich, Nurit ^a   DiPaolo, Brian C ^a   Lawrence, Gladys G ^a   Chhour, Peter ^a   Yehya, Nadir ^a   Margulies, Susan S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Acute lung injury; MAPK; Mechanical deformation; P65; Ventilator induced lung injury

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANTIOXIDANT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; I KAPPA B; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; OUABAIN; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; TIRON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CELL ACTIVATION; CELL CULTURE; CELL ISOLATION; CELL STIMULATION; CELL TYPE; CONTROLLED STUDY; DRUG EFFECT; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS; LUNG ALVEOLUS EPITHELIUM; MALE; MONOLAYER CULTURE; NONHUMAN; OXIDATIVE STRESS; PERMEABILITY; PHOSPHORYLATION; RAT; TIGHT JUNCTION; VENTILATOR INDUCED LUNG INJURY; WNT SIGNALING PATHWAY;

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT; ANIMALS; ANTIOXIDANTS; BUTADIENES; CELL MEMBRANE PERMEABILITY; EPITHELIAL CELLS; LEUPEPTINS; MALE; NF-KAPPA B; NITRIC OXIDE; NITRILES; OXIDATIVE STRESS; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; SIGNAL TRANSDUCTION; SUPEROXIDES; VENTILATOR-INDUCED LUNG INJURY;

EID: 84882927097     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0252OC     Document Type: Article

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