메뉴 건너뛰기




Volumn 71, Issue 8, 2011, Pages 981-1001

New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis

Author keywords

Acetylcysteine; Anticoagulants; Azathioprine; Bosentan; Corticosteroids; Etanercept; Idiopathic pulmonary fibrosis; Imatinib; Interferon; Interferon gamma; Oxygen; Pirfenidone; Prednisone; Sildenafil.

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCYSTEINE; ANTICOAGULANT AGENT; ANTIOXIDANT; AZATHIOPRINE; BOSENTAN; CORTICOSTEROID; ETANERCEPT; FASUDIL; GAMMA1B INTERFERON; IMATINIB; LOW MOLECULAR WEIGHT HEPARIN; METHYLPREDNISOLONE; MICRORNA; PIRFENIDONE; PLACEBO; PREDNISONE; PROTEIN KINASE INHIBITOR; RHO KINASE INHIBITOR; SILDENAFIL; SLX 2119; UNCLASSIFIED DRUG; WARFARIN;

EID: 79958788032     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/11591490-000000000-00000     Document Type: Review
Times cited : (52)

References (188)
  • 1
    • 0037080547 scopus 로고    scopus 로고
    • This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors
    • American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias June 2001 and by the ERS Executive Committee, June 2001
    • American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 2002; 165 (2): 277-304.
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.2 , pp. 277-304
  • 3
    • 0029929285 scopus 로고    scopus 로고
    • Predictors of survival in patients receiving domiciliary oxygen therapy or mechanical ventilation: A 10-year analysis of ANTADIR observatory
    • Chailleux E, Fauroux B, Binet F, et al. Predictors of survival in patients receiving domiciliary oxygen therapy or mechanical ventilation: a 10-year analysis of ANTADIR Observatory. Chest 1996; 109 (3): 741-9. (Pubitemid 26086943)
    • (1996) Chest , vol.109 , Issue.3 , pp. 741-749
    • Chailleux, E.1    Fauroux, B.2    Binet, F.3    Dautzenberg, B.4    Polu, J.-M.5
  • 4
    • 17144401893 scopus 로고    scopus 로고
    • Evaluation of health-related quality-of-life and dyspnea scales in patients with idiopathic pulmonary fibrosis. Correlation with pulmonary function tests
    • DOI 10.1016/j.ejim.2004.09.013
    • Tzanakis N, Samiou M, Lambiri I, et al. Evaluation of healthrelated quality-of-life and dyspnea scales in patients with idiopathic pulmonary fibrosis: correlation with pulmonary function tests. Eur J Intern Med 2005; 16 (2): 105-12. (Pubitemid 40523053)
    • (2005) European Journal of Internal Medicine , vol.16 , Issue.2 , pp. 105-112
    • Tzanakis, N.1    Samiou, M.2    Lambiri, I.3    Antoniou, K.4    Siafakas, N.5    Bouros, D.6
  • 6
  • 9
    • 33645124084 scopus 로고    scopus 로고
    • Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: A case series
    • Raghu G, Yang ST, Spada C, et al. Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: a case series. Chest 2006; 129 (3): 794-800.
    • (2006) Chest , vol.129 , Issue.3 , pp. 794-800
    • Raghu, G.1    Yang, S.T.2    Spada, C.3
  • 10
    • 70049102004 scopus 로고    scopus 로고
    • Obstructive sleep apnea is common in idiopathic pulmonary fibrosis
    • Lancaster LH, Mason WR, Parnell JA, et al. Obstructive sleep apnea is common in idiopathic pulmonary fibrosis. Chest 2009; 136 (3): 772-8.
    • (2009) Chest , vol.136 , Issue.3 , pp. 772-778
    • Lancaster, L.H.1    Mason, W.R.2    Parnell, J.A.3
  • 11
    • 57149114526 scopus 로고    scopus 로고
    • The association between idiopathic pulmonary fibrosis and vascular disease: A population-based study
    • Hubbard RB, Smith C, Le Jeune I, et al. The association between idiopathic pulmonary fibrosis and vascular disease: a population-based study. Am J Respir Crit Care Med 2008; 178 (12): 1257-61.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.12 , pp. 1257-1261
    • Hubbard, R.B.1    Smith, C.2    Le Jeune, I.3
  • 12
    • 77952882026 scopus 로고    scopus 로고
    • Prevalence and impact of coronary artery disease in idiopathic pulmonary fibrosis
    • Nathan SD, Basavaraj A, Reichner C, et al. Prevalence and impact of coronary artery disease in idiopathic pulmonary fibrosis. Respir Med 2010; 104 (7): 1035-41.
    • (2010) Respir Med , vol.104 , Issue.7 , pp. 1035-1041
    • Nathan, S.D.1    Basavaraj, A.2    Reichner, C.3
  • 13
    • 33645118315 scopus 로고    scopus 로고
    • Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis
    • Lettieri CJ, Nathan SD, Barnett SD, et al. Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis. Chest 2006; 129 (3): 746-52.
    • (2006) Chest , vol.129 , Issue.3 , pp. 746-752
    • Lettieri, C.J.1    Nathan, S.D.2    Barnett, S.D.3
  • 15
    • 0034011982 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment. International consensus statement
    • American Thoracic Society American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 2000; 161 (2 Pt 1): 646-64.
    • (2000) Am J Respir Crit Care Med , vol.161 , Issue.2 PART 1 , pp. 646-664
  • 20
    • 37849012578 scopus 로고    scopus 로고
    • BUILD-1: A randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
    • King Jr TE, Behr J, Brown KK, et al. BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 177 (1): 75-81.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.1 , pp. 75-81
    • King Jr., T.E.1    Behr, J.2    Brown, K.K.3
  • 21
    • 55549147184 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with etanercept: An exploratory, placebo-controlled trial
    • Raghu G, Brown KK, Costabel U, et al. Treatment of idiopathic pulmonary fibrosis with etanercept: an exploratory, placebo-controlled trial. Am J Respir Crit Care Med 2008; 178 (9): 948-55.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.9 , pp. 948-955
    • Raghu, G.1    Brown, K.K.2    Costabel, U.3
  • 22
    • 67650349068 scopus 로고    scopus 로고
    • Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebo-controlled trial
    • King Jr TE, Albera C, Bradford WZ, et al. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet 2009; 374 (9685): 222-8.
    • (2009) Lancet , vol.374 , Issue.9685 , pp. 222-228
    • King Jr., T.E.1    Albera, C.2    Bradford, W.Z.3
  • 23
    • 77749324295 scopus 로고    scopus 로고
    • Imatinib treatment for idiopathic pulmonary fibrosis: Randomized placebo- controlled trial results
    • Daniels CE, Lasky JA, Limper AH, et al. Imatinib treatment for idiopathic pulmonary fibrosis: randomized placebo- controlled trial results. Am J Respir Crit Care Med 2010; 181 (6): 604-10.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.6 , pp. 604-610
    • Daniels, C.E.1    Lasky, J.A.2    Limper, A.H.3
  • 24
    • 79956341531 scopus 로고    scopus 로고
    • Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials
    • for the CAPACITY Study Group. Epub 2011 May 13
    • Noble PW, Albera C, Bradford WZ, et al., for the CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet. Epub 2011 May 13.
    • Lancet
    • Noble, P.W.1    Walbera, C.2    Bradford, W.Z.3
  • 25
    • 77951160564 scopus 로고    scopus 로고
    • Pirfenidone in idiopathic pulmonary fibrosis
    • Taniguchi H, Ebina M, Kondoh Y, et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 2010; 35 (4): 821-9.
    • (2010) Eur Respir J , vol.35 , Issue.4 , pp. 821-829
    • Taniguchi, H.1    Ebina, M.2    Kondoh, Y.3
  • 26
    • 77956640423 scopus 로고    scopus 로고
    • A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis
    • Zisman DA, Schwarz M, Anstrom KJ, et al. A controlled trial of sildenafil in advanced idiopathic pulmonary fibrosis. N Engl J Med 2010; 363 (7): 620-8.
    • (2010) N Engl J Med , vol.363 , Issue.7 , pp. 620-628
    • Zisman, D.A.1    Schwarz, M.2    Anstrom, K.J.3
  • 27
    • 20544443765 scopus 로고    scopus 로고
    • The clinical course of patients with idiopathic pulmonary fibrosis
    • Martinez FJ, Safrin S, Weycker D, et al. The clinical course of patients with idiopathic pulmonary fibrosis. Ann Intern Med 2005; 142 (12 Pt 1): 963-7.
    • (2005) Ann Intern Med , vol.142 , Issue.12 PART 1 , pp. 963-967
    • Martinez, F.J.1    Safrin, S.2    Weycker, D.3
  • 31
    • 84857108790 scopus 로고    scopus 로고
    • Pulmonary-Allergy Drugs Advisory Committee [Accessed 2011 May 25]
    • Pulmonary-Allergy Drugs Advisory Committee. Pirfenidone NDA 22-535 [online]. Available from URL: http://www.fda.gov/downloads/AdvisoryCommittees/ CommitteesMeetingMaterials/Drugs/Pulmonary-AllergyDrugsAdvisoryCommittee/ UCM206399.pdf [Accessed 2011 May 25].
    • Pirfenidone NDA 22-535 [Online]
  • 32
    • 0025012363 scopus 로고
    • What causes cryptogenic fibrosing alveolitis? A case-control study of environmental exposure to dust
    • Scott J, Johnston I, Britton J. What causes cryptogenic fibrosing alveolitis? A case-control study of environmental exposure to dust. BMJ 1990; 301 (6759): 1015-7. (Pubitemid 20381075)
    • (1990) British Medical Journal , vol.301 , Issue.6759 , pp. 1015-1017
    • Scott, J.1    Johnston, I.2    Britton, J.3
  • 33
    • 0030034711 scopus 로고    scopus 로고
    • Occupational exposure to metal or wood dust and aetiology of cryptogenic fibrosing alveolitis
    • DOI 10.1016/S0140-6736(96)90465-1
    • Hubbard R, Lewis S, Richards K, et al. Occupational exposure tometal or wood dust and aetiology of cryptogenic fibrosing alveolitis. Lancet 1996; 347 (8997): 284-9. (Pubitemid 26041039)
    • (1996) Lancet , vol.347 , Issue.8997 , pp. 284-289
    • Hubbard, R.1    Lewis, S.2    Richards, K.3    Johnston, I.4    Britton, J.5
  • 40
    • 34547418228 scopus 로고    scopus 로고
    • Inhalation of inorganic particles as a risk factor for idiopathic pulmonary fibrosis-Elemental microanalysis of pulmonary lymph nodes obtained at autopsy cases
    • DOI 10.1016/j.prp.2007.04.008, PII S0344033807000891
    • Kitamura H, Ichinose S, Hosoya T, et al. Inhalation of inorganic particles as a risk factor for idiopathic pulmonary fibrosis: elemental microanalysis of pulmonary lymph nodes obtained at autopsy cases. Pathol Res Pract 2007; 203 (8): 575-85. (Pubitemid 47163498)
    • (2007) Pathology Research and Practice , vol.203 , Issue.8 , pp. 575-585
    • Kitamura, H.1    Ichinose, S.2    Hosoya, T.3    Ando, T.4    Ikushima, S.5    Oritsu, M.6    Takemura, T.7
  • 41
    • 0037790724 scopus 로고    scopus 로고
    • Diabetes mellitus may increase risk for idiopathic pulmonary fibrosis
    • DOI 10.1378/chest.123.6.2007
    • Enomoto T, Usuki J, Azuma A, et al. Diabetes mellitus may increase risk for idiopathic pulmonary fibrosis. Chest 2003; 123 (6): 2007-11. (Pubitemid 36706726)
    • (2003) Chest , vol.123 , Issue.6 , pp. 2007-2011
    • Enomoto, T.1    Usuki, J.2    Azuma, A.3    Nakagawa, T.4    Kudoh, S.5
  • 43
    • 33744908816 scopus 로고    scopus 로고
    • Is idiopathic pulmonary fibrosis an environmental disease?
    • DOI 10.1513/pats.200512-131TK
    • Taskar VS, Coultas DB. Is idiopathic pulmonary fibrosis an environmental disease? Proc Am Thorac Soc 2006; 3 (4): 293-8. (Pubitemid 43845405)
    • (2006) Proceedings of the American Thoracic Society , vol.3 , Issue.4 , pp. 293-298
    • Taskar, V.S.1    Coultas, D.B.2
  • 44
    • 73749083315 scopus 로고    scopus 로고
    • Risk factors for idiopathic pulmonary fibrosis in a Mexican population: A case-control study
    • Garcia-Sancho Figueroa MC, Carrillo G, Perez-Padilla R, et al. Risk factors for idiopathic pulmonary fibrosis in a Mexican population: a case-control study. Respir Med 2010; 104 (2): 305-9.
    • (2010) Respir Med , vol.104 , Issue.2 , pp. 305-309
    • Garcia-Sancho Figueroa, M.C.1    Carrillo, G.2    Perez-Padilla, R.3
  • 45
    • 38349039634 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Outcome in relation to smoking status
    • Antoniou KM, Hansell DM, Rubens MB, et al. Idiopathic pulmonary fibrosis: outcome in relation to smoking status. Am J Respir Crit Care Med 2008; 177 (2): 190-4.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.2 , pp. 190-194
    • Antoniou, K.M.1    Hansell, D.M.2    Rubens, M.B.3
  • 48
    • 67349242705 scopus 로고    scopus 로고
    • Role of diabetes mellitus and gastro-oesophageal reflux in the aetiology of idiopathic pulmonary fibrosis
    • Gribbin J, Hubbard R, Smith C. Role of diabetes mellitus and gastro-oesophageal reflux in the aetiology of idiopathic pulmonary fibrosis. Respir Med 2009; 103 (6): 927-31.
    • (2009) Respir Med , vol.103 , Issue.6 , pp. 927-931
    • Gribbin, J.1    Hubbard, R.2    Smith, C.3
  • 49
    • 63349106611 scopus 로고    scopus 로고
    • Gastroesophageal reflux and pulmonary fibrosis in scleroderma: A study using pH-impedance monitoring
    • Savarino E, Bazzica M, Zentilin P, et al. Gastroesophageal reflux and pulmonary fibrosis in scleroderma: a study using pH-impedance monitoring. Am J Respir Crit Care Med 2009; 179 (5): 408-13.
    • (2009) Am J Respir Crit Care Med , vol.179 , Issue.5 , pp. 408-413
    • Savarino, E.1    Bazzica, M.2    Zentilin, P.3
  • 51
    • 56449105355 scopus 로고    scopus 로고
    • Prevalence of gastroesophageal reflux in lung transplant candidates with advanced lung disease
    • FortunatoGA, Machado MM, Andrade CF, et al. Prevalence of gastroesophageal reflux in lung transplant candidates with advanced lung disease. J Bras Pneumol 2008; 34 (10): 772-8.
    • (2008) J Bras Pneumol , vol.34 , Issue.10 , pp. 772-778
    • Fortunato, G.A.1    MacHado, M.M.2    Andrade, C.F.3
  • 53
    • 70249113403 scopus 로고    scopus 로고
    • Blockade of advanced glycation end product formation attenuates bleomycininduced pulmonary fibrosis in rats
    • Chen L, Wang T, Wang X, et al. Blockade of advanced glycation end product formation attenuates bleomycininduced pulmonary fibrosis in rats. Respir Res 2009; 10: 55.
    • (2009) Respir Res , vol.10 , pp. 55
    • Chen, L.1    Wang, T.2    Wang, X.3
  • 55
    • 51249114838 scopus 로고    scopus 로고
    • Loss of RAGE in pulmonary fibrosis: Molecular relations to functional changes in pulmonary cell types
    • Queisser MA, Kouri FM, Konigshoff M, et al. Loss of RAGE in pulmonary fibrosis: molecular relations to functional changes in pulmonary cell types. Am J Respir Cell Mol Biol 2008; 39 (3): 337-45.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , Issue.3 , pp. 337-345
    • Queisser, M.A.1    Kouri, F.M.2    Konigshoff, M.3
  • 56
    • 0037102396 scopus 로고    scopus 로고
    • A rearranged form of Epstein-Barr virus DNA is associated with idiopathic pulmonary fibrosis
    • Kelly BG, Lok SS, Hasleton PS, et al. A rearranged form of Epstein-Barr virus DNA is associated with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2002; 166 (4): 510-3.
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.4 , pp. 510-513
    • Kelly, B.G.1    Lok, S.S.2    Hasleton, P.S.3
  • 57
  • 60
    • 48949119341 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection
    • Lawson WE, Crossno PF, Polosukhin VV, et al. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol 2008; 294 (6): L1119-26.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , Issue.6
    • Lawson, W.E.1    Crossno, P.F.2    Polosukhin, V.V.3
  • 61
    • 0037373514 scopus 로고    scopus 로고
    • Lack of evidence for a role of Epstein-Barr virus in the increase of lung cancer in idiopathic pulmonary fibrosis
    • DOI 10.1053/rmed.2003.1398
    • Hayakawa H, Shirai M, Uchiyama H, et al. Lack of evidence for a role of Epstein-Barr virus in the increase of lung cancer in idiopathic pulmonary fibrosis. Respir Med 2003; 97 (3): 281-4. (Pubitemid 36266885)
    • (2003) Respiratory Medicine , vol.97 , Issue.3 , pp. 281-284
    • Hayakawa, H.1    Shirai, M.2    Uchiyama, H.3    Imokawa, S.4    Suda, T.5    Chida, K.6    Muro, H.7
  • 65
    • 0021077452 scopus 로고
    • Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorder
    • Bitterman PB, Adelberg S, Crystal RG. Mechanisms of pulmonary fibrosis: spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. J Clin Invest 1983; 72 (5): 1801-13. (Pubitemid 14229060)
    • (1983) Journal of Clinical Investigation , vol.72 , Issue.5 , pp. 1801-1813
    • Bitterman, P.B.1    Adelberg, S.2    Crystal, R.G.3
  • 66
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • SelmanM,King TE, PardoA. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann InternMed 2001; 134 (2): 136-51. (Pubitemid 32096342)
    • (2001) Annals of Internal Medicine , vol.134 , Issue.2 , pp. 136-151
    • Selman, M.1    King Jr., T.E.2    Pardo, A.3
  • 67
    • 0042171695 scopus 로고    scopus 로고
    • A clinical study of idiopathic pulmonary fibrosis based on autopsy studies in elderly patients
    • Araki T, Katsura H, Sawabe M, et al. A clinical study of idiopathic pulmonary fibrosis based on autopsy studies in elderly patients. Intern Med 2003; 42 (6): 483-9. (Pubitemid 36926809)
    • (2003) Internal Medicine , vol.42 , Issue.6 , pp. 483-489
    • Araki, T.1    Katsura, H.2    Sawabe, M.3    Kida, K.4
  • 68
    • 71149086939 scopus 로고    scopus 로고
    • Short telomeres are sufficient to cause the degenerative defects associated with aging
    • Armanios M, Alder JK, Parry EM, et al. Short telomeres are sufficient to cause the degenerative defects associated with aging. Am J Hum Genet 2009; 85 (6): 823-32.
    • (2009) Am J Hum Genet , vol.85 , Issue.6 , pp. 823-832
    • Armanios, M.1    Alder, J.K.2    Parry, E.M.3
  • 69
    • 34548667973 scopus 로고    scopus 로고
    • Telomere length, stem cells and aging
    • DOI 10.1038/nchembio.2007.38, PII NCHEMBIO200738
    • Blasco MA. Telomere length, stem cells and aging. Nat Chem Biol 2007; 3 (10): 640-9. (Pubitemid 47417712)
    • (2007) Nature Chemical Biology , vol.3 , Issue.10 , pp. 640-649
    • Blasco, M.A.1
  • 71
    • 51349113450 scopus 로고    scopus 로고
    • Short telomeres are a risk factor for idiopathic pulmonary fibrosis
    • Alder JK, Chen JJ, Lancaster L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci USA 2008; 105 (35): 13051-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.35 , pp. 13051-6
    • Alder, J.K.1    Chen, J.J.2    Lancaster, L.3
  • 72
    • 52749083873 scopus 로고    scopus 로고
    • Telomere shortening in familial and sporadic pulmonary fibrosis
    • Cronkhite JT, Xing C, RaghuG, et al. Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 178 (7): 729-37.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.7 , pp. 729-737
    • Cronkhite, J.T.1    Xing, C.2    Raghu, G.3
  • 73
    • 52749089332 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: A disorder of lung regeneration?
    • Thannickal VJ, Loyd JE. Idiopathic pulmonary fibrosis: a disorder of lung regeneration?Am J Respir Crit Care Med 2008; 178 (7): 663-5.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.7 , pp. 663-665
    • Thannickal, V.J.1    Loyd, J.E.2
  • 74
    • 0021705255 scopus 로고
    • Chronic cigarette smoke inhalation and aging in mice: 1. Morphologic and functional lung abnormalities
    • Matulionis DH. Chronic cigarette smoke inhalation and aging in mice: 1, morphologic and functional lung abnormalities. Exp Lung Res 1984; 7 (3-4): 237-56. (Pubitemid 15173751)
    • (1984) Experimental Lung Research , vol.7 , Issue.3-4 , pp. 237-256
    • Matulionis, D.H.1
  • 76
    • 73449140168 scopus 로고    scopus 로고
    • Molecular pathogenesis of liver fibrosis
    • Brenner DA. Molecular pathogenesis of liver fibrosis. Trans Am Clin Climatol Assoc 2009; 120: 361-8.
    • (2009) Trans Am Clin Climatol Assoc , vol.120 , pp. 361-368
    • Brenner, D.A.1
  • 78
    • 0031761169 scopus 로고    scopus 로고
    • 8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases
    • Montuschi P, Ciabattoni G, Paredi P, et al. 8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases. Am J Respir Crit Care Med 1998; 158 (5 Pt 1): 1524-7.
    • (1998) Am J Respir Crit Care Med , vol.158 , Issue.5 PART 1 , pp. 1524-1527
    • Montuschi, P.1    Ciabattoni, G.2    Paredi, P.3
  • 80
    • 34347257042 scopus 로고    scopus 로고
    • Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
    • DOI 10.1016/j.freeradbiomed.2007.03.027, PII S0891584907002225
    • Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med 2007; 43 (3): 332-47. (Pubitemid 46992767)
    • (2007) Free Radical Biology and Medicine , vol.43 , Issue.3 , pp. 332-347
    • Lambeth, J.D.1
  • 81
    • 33845345975 scopus 로고    scopus 로고
    • Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements
    • DOI 10.1158/0008-5472.CAN-06-1236
    • Dasari A, Bartholomew JN, Volonte D, et al. Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogenactivated protein kinase/Sp1-mediated activation of two GC-rich promoter elements. Cancer Res 2006; 66 (22): 10805-14. (Pubitemid 44876976)
    • (2006) Cancer Research , vol.66 , Issue.22 , pp. 10805-10814
    • Dasari, A.1    Bartholomew, J.N.2    Volonte, D.3    Galbiati, F.4
  • 82
    • 70349129549 scopus 로고    scopus 로고
    • Accelerated lung aging: A novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)
    • MacNee W. Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD). Biochem Soc Trans 2009; 37 (Pt 4): 819-23.
    • (2009) Biochem Soc Trans , vol.37 , Issue.PART 4 , pp. 819-823
    • MacNee, W.1
  • 83
    • 0029023626 scopus 로고
    • Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved
    • Wang E. Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. Cancer Res 1995; 55 (11): 2284-92.
    • (1995) Cancer Res , vol.55 , Issue.11 , pp. 2284-2292
    • Wang, E.1
  • 84
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: When bad things happen to good cells
    • DOI 10.1038/nrm2233, PII NRM2233
    • Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007; 8 (9): 729-40. (Pubitemid 47312822)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 729-740
    • Campisi, J.1    D'Adda Di Fagagna, F.2
  • 85
    • 0033732110 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
    • Toussaint O, Medrano EE, von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol 2000; 35 (8): 927-45.
    • (2000) Exp Gerontol , vol.35 , Issue.8 , pp. 927-945
    • Toussaint, O.1    Medrano, E.E.2    Von Zglinicki, T.3
  • 86
    • 18144371956 scopus 로고    scopus 로고
    • Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts
    • DOI 10.1096/fj.04-2882fje
    • Waghray M, Cui Z, Horowitz JC, et al. Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts. FASEB J 2005; 19 (7): 854-6. (Pubitemid 40617407)
    • (2005) FASEB Journal , vol.19 , Issue.7 , pp. 854-856
    • Waghray, M.1    Cui, Z.2    Horowitz, J.C.3    Subramanian, I.M.4    Martinez, F.J.5    Toews, G.B.6    Thannickal, V.J.7
  • 87
    • 0035907349 scopus 로고    scopus 로고
    • Oxidative protein cross-linking reactions involving L-tyrosine in transforming growth factor-beta1-stimulated fibroblasts
    • Larios JM, Budhiraja R, Fanburg BL, et al. Oxidative protein cross-linking reactions involving L-tyrosine in transforming growth factor-beta1-stimulated fibroblasts. J Biol Chem 2001; 276 (20): 17437-41.
    • (2001) J Biol Chem , vol.276 , Issue.20 , pp. 17437-41
    • Larios, J.M.1    Budhiraja, R.2    Fanburg, B.L.3
  • 88
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • DOI 10.1172/JCI26373
    • Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. JClin Invest 2005; 115 (10): 2656-64. (Pubitemid 41434389)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 89
    • 54049115076 scopus 로고    scopus 로고
    • Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
    • Korfei M, Ruppert C, Mahavadi P, et al. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 178 (8): 838-46.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.8 , pp. 838-846
    • Korfei, M.1    Ruppert, C.2    Mahavadi, P.3
  • 91
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-β1: Potential role in idiopathic pulmonary fibrosis
    • Willis BC, Liebler JM, Luby-Phelps K, et al. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 2005; 166 (5): 1321-32. (Pubitemid 40586504)
    • (2005) American Journal of Pathology , vol.166 , Issue.5 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    Du Bois, R.M.6    Borok, Z.7
  • 93
    • 70349441112 scopus 로고    scopus 로고
    • Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
    • Tanjore H, Xu XC, Polosukhin VV, et al. Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med 2009; 180 (7): 657-65.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.7 , pp. 657-665
    • Tanjore, H.1    Xu, X.C.2    Polosukhin, V.V.3
  • 95
    • 33746977705 scopus 로고    scopus 로고
    • Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis
    • Chilosi M, Zamo A, Doglioni C, et al. Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis. Respir Res 2006; 7: 95.
    • (2006) Respir Res , vol.7 , pp. 95
    • Chilosi, M.1    Zamo, A.2    Doglioni, C.3
  • 96
    • 77955481200 scopus 로고    scopus 로고
    • Endothelialmesenchymal transition in bleomycin-induced pulmonary fibrosis
    • Hashimoto N, Phan SH, Imaizumi K, et al. Endothelialmesenchymal transition in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 2009; 43 (2): 161-72.
    • (2009) Am J Respir Cell Mol Biol , vol.43 , Issue.2 , pp. 161-172
    • Hashimoto, N.1    Phan, S.H.2    Imaizumi, K.3
  • 97
    • 0037378123 scopus 로고    scopus 로고
    • Unique structural features that influence neutrophil emigration into the lung
    • Burns AR, Smith CW, Walker DC. Unique structural features that influence neutrophil emigration into the lung. Physiol Rev 2003; 83 (2): 309-36. (Pubitemid 36378675)
    • (2003) Physiological Reviews , vol.83 , Issue.2 , pp. 309-336
    • Burns, A.R.1    Smith, C.W.2    Walker, D.C.3
  • 101
    • 3242797250 scopus 로고    scopus 로고
    • Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-β in response to fibrogenic stimuli
    • Zhou Y, Hagood JS, Murphy-Ullrich JE. Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-beta in response to fibrogenic stimuli. Am J Pathol 2004; 165 (2): 659-69. (Pubitemid 38971395)
    • (2004) American Journal of Pathology , vol.165 , Issue.2 , pp. 659-669
    • Zhou, Y.1    Hagood, J.S.2    Murphy-Ullrich, J.E.3
  • 102
    • 33749077290 scopus 로고    scopus 로고
    • Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses
    • DOI 10.1016/j.bbamcr.2006.08.008, PII S0167488906002230
    • Rege TA, Hagood JS. Thy-1, a versatile modulator of signaling affecting cellular adhesion, proliferation, survival, and cytokine/growth factor responses. Biochim Biophys Acta 2006; 1763 (10): 991-9. (Pubitemid 44466122)
    • (2006) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1763 , Issue.10 , pp. 991-999
    • Rege, T.A.1    Hagood, J.S.2
  • 103
    • 58249098406 scopus 로고    scopus 로고
    • Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin
    • Zhou Y, Koli K, Hagood JS, et al. Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin. Am J Pathol 2009; 174 (1): 21-33.
    • (2009) Am J Pathol , vol.174 , Issue.1 , pp. 21-33
    • Zhou, Y.1    Koli, K.2    Hagood, J.S.3
  • 104
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
    • Bartel DP, Chen CZ. Micromanagers of gene expression: the potentially widespread influence of metazoan micro- RNAs. Nat Rev Genet 2004; 5 (5): 396-400. (Pubitemid 38529411)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.-Z.2
  • 105
    • 51349141401 scopus 로고    scopus 로고
    • Dysregulation ofmicroRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
    • van Rooij E, Sutherland LB, Thatcher JE, et al. Dysregulation ofmicroRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA 2008; 105 (35): 13027-32.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.35 , pp. 13027-32
    • Van Rooij, E.1    Sutherland, L.B.2    Thatcher, J.E.3
  • 106
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008; 456 (7224): 980-4.
    • (2008) Nature , vol.456 , Issue.7224 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 107
    • 77955399498 scopus 로고    scopus 로고
    • Inhibition and role of let-7d in idiopathic pulmonary fibrosis
    • Pandit KV, Corcoran D, Yousef H, et al. Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010; 182 (2): 220-9.
    • (2010) Am J Respir Crit Care Med , vol.182 , Issue.2 , pp. 220-229
    • Pandit, K.V.1    Corcoran, D.2    Yousef, H.3
  • 108
    • 77955373730 scopus 로고    scopus 로고
    • MiR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
    • Liu G, Friggeri A, Yang Y, et al. miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med 2010; 207 (8): 1589-97.
    • (2010) J Exp Med , vol.207 , Issue.8 , pp. 1589-1597
    • Liu, G.1    Friggeri, A.2    Yang, Y.3
  • 110
    • 67651111989 scopus 로고    scopus 로고
    • Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines
    • Shan H, Zhang Y, Lu Y, et al. Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines. Cardiovasc Res 2009; 83 (3): 465-72.
    • (2009) Cardiovasc Res , vol.83 , Issue.3 , pp. 465-472
    • Shan, H.1    Zhang, Y.2    Lu, Y.3
  • 111
    • 59849128881 scopus 로고    scopus 로고
    • MiR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling
    • 6p following 178
    • Duisters RF, Tijsen AJ, Schroen B, et al. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res 2009; 104 (2): 170-8, 6p following 178.
    • (2009) Circ Res , vol.104 , Issue.2 , pp. 170-178
    • Duisters, R.F.1    Tijsen, A.J.2    Schroen, B.3
  • 112
    • 80051655553 scopus 로고    scopus 로고
    • MIR-29 is a major regulator of genes associated with pulmonary fibrosis
    • Epub 2010 Oct 22
    • Cushing L, Kuang PP, Qian J, et al. MIR-29 is a major regulator of genes associated with pulmonary fibrosis. Am J Respir Cell Mol Biol. Epub 2010 Oct 22.
    • Am J Respir Cell Mol Biol
    • Cushing, L.1    Kuang, P.P.2    Qian, J.3
  • 113
    • 75649113377 scopus 로고    scopus 로고
    • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
    • Sheedy FJ, Palsson-McDermott E, Hennessy EJ, et al. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol 2010; 11 (2): 141-7.
    • (2010) Nat Immunol , vol.11 , Issue.2 , pp. 141-147
    • Sheedy, F.J.1    Palsson-Mcdermott, E.2    Hennessy, E.J.3
  • 114
    • 77954797933 scopus 로고    scopus 로고
    • Ischaemic preconditioningregulated miR-21 protects heart against ischaemia/ reperfusion injury via anti-apoptosis through its target PDCD4
    • Cheng Y, Zhu P, Yang J, et al. Ischaemic preconditioningregulated miR-21 protects heart against ischaemia/ reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res 2010; 87 (3): 431-9.
    • (2010) Cardiovasc Res , vol.87 , Issue.3 , pp. 431-439
    • Cheng, Y.1    Zhu, P.2    Yang, J.3
  • 115
    • 77956501846 scopus 로고    scopus 로고
    • Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21
    • Hatley ME, Patrick DM, Garcia MR, et al. Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell 2010; 18 (3): 282-93.
    • (2010) Cancer Cell , vol.18 , Issue.3 , pp. 282-293
    • Hatley, M.E.1    Patrick, D.M.2    Garcia, M.R.3
  • 116
    • 62349141343 scopus 로고    scopus 로고
    • MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
    • Roy S, Khanna S, Hussain SR, et al. MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc Res 2009; 82 (1): 21-9.
    • (2009) Cardiovasc Res , vol.82 , Issue.1 , pp. 21-29
    • Roy, S.1    Khanna, S.2    Hussain, S.R.3
  • 117
    • 67650085171 scopus 로고    scopus 로고
    • TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
    • Kato M, Putta S, Wang M, et al. TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat Cell Biol 2009; 11 (7): 881-9.
    • (2009) Nat Cell Biol , vol.11 , Issue.7 , pp. 881-889
    • Kato, M.1    Putta, S.2    Wang, M.3
  • 118
    • 68249126627 scopus 로고    scopus 로고
    • MicroRNA MiR-17 retards tissue growth and represses fibronectin expression
    • Shan SW, Lee DY, Deng Z, et al. MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol 2009; 11 (8): 1031-8.
    • (2009) Nat Cell Biol , vol.11 , Issue.8 , pp. 1031-1038
    • Shan, S.W.1    Lee, D.Y.2    Deng, Z.3
  • 119
    • 68449097267 scopus 로고    scopus 로고
    • MiR-145 and miR-143 regulate smooth muscle cell fate and plasticity
    • Cordes KR, Sheehy NT, White MP, et al. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature 2009; 460 (7256): 705-10.
    • (2009) Nature , vol.460 , Issue.7256 , pp. 705-710
    • Cordes, K.R.1    Sheehy, N.T.2    White, M.P.3
  • 120
    • 69249202575 scopus 로고    scopus 로고
    • Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: Implication in epithelial-mesenchymal interactions
    • Pottier N, Maurin T, Chevalier B, et al. Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions. PLoS One 2009; 4 (8): e6718.
    • (2009) PLoS One , vol.4 , Issue.8
    • Pottier, N.1    Maurin, T.2    Chevalier, B.3
  • 123
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • DOI 10.1101/gad.1640608
    • Park SM, Gaur AB, Lengyel E, et al. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22 (7): 894-907. (Pubitemid 351482843)
    • (2008) Genes and Development , vol.22 , Issue.7 , pp. 894-907
    • Park, S.-M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 124
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, et al. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283 (22): 14910-4.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-4
    • Korpal, M.1    Lee, E.S.2    Hu, G.3
  • 125
    • 65649146879 scopus 로고    scopus 로고
    • The mechanical integrin cycle
    • Puklin-Faucher E, Sheetz MP. The mechanical integrin cycle. J Cell Sci 2009; 122 (Pt 2): 179-86.
    • (2009) J Cell Sci , vol.122 , Issue.PART 2 , pp. 179-186
    • Puklin-Faucher, E.1    Sheetz, M.P.2
  • 126
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
    • DOI 10.1083/jcb.200704042
    • Wipff PJ, Rifkin DB, Meister JJ, et al. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol 2007; 179 (6): 1311-23. (Pubitemid 350277747)
    • (2007) Journal of Cell Biology , vol.179 , Issue.6 , pp. 1311-1323
    • Wipff, P.-J.1    Rifkin, D.B.2    Meister, J.-J.3    Hinz, B.4
  • 127
    • 0028906190 scopus 로고
    • Processing of transforming growth factor beta 1 precursor by human furin convertase
    • Dubois CM, Laprise MH, Blanchette F, et al. Processing of transforming growth factor beta 1 precursor by human furin convertase. J Biol Chem 1995; 270 (18): 10618-24.
    • (1995) J Biol Chem , vol.270 , Issue.18 , pp. 10618-24
    • Dubois, C.M.1    Laprise, M.H.2    Blanchette, F.3
  • 129
    • 0022335318 scopus 로고
    • Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions
    • Lawrence DA, Pircher R, Jullien P. Conversion of a high molecular weight latent beta-TGF from chicken embryo fibroblasts into a low molecular weight active beta-TGF under acidic conditions. Biochem Biophys Res Commun 1985; 133 (3): 1026-34. (Pubitemid 16142882)
    • (1985) Biochemical and Biophysical Research Communications , vol.133 , Issue.3 , pp. 1026-1034
    • Lawrence, D.A.1    Pircher, R.2    Jullien, P.3
  • 130
    • 0034865421 scopus 로고    scopus 로고
    • Novel non-TGF-β-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-β deposition
    • Koli K, Saharinen J, Karkkainen M, et al. Novel non- TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition. J Cell Sci 2001; 114 (Pt 15): 2869-78. (Pubitemid 32785465)
    • (2001) Journal of Cell Science , vol.114 , Issue.15 , pp. 2869-2878
    • Koli, K.1    Saharinen, J.2    Karkkainen, M.3    Keski-Oja, J.4
  • 131
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGFβ activation
    • DOI 10.1242/jcs.00229
    • Annes JP, Munger JS, Rifkin DB. Making sense of latent TGFbeta activation. J Cell Sci 2003; 116 (Pt 2): 217-24. (Pubitemid 36163863)
    • (2003) Journal of Cell Science , vol.116 , Issue.2 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 132
    • 3042838388 scopus 로고    scopus 로고
    • Latent TGF-β binding proteins: Extracellular matrix association and roles in TGF-β activation
    • DOI 10.1080/10408360490460933
    • Hyytiainen M, Penttinen C, Keski-Oja J. Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation. Crit Rev Clin Lab Sci 2004; 41 (3): 233-64. (Pubitemid 38888060)
    • (2004) Critical Reviews in Clinical Laboratory Sciences , vol.41 , Issue.3 , pp. 233-264
    • Hyytiainen, M.1    Penttinen, C.2    Keski-Oja, J.3
  • 135
    • 0030800795 scopus 로고    scopus 로고
    • Adenovector-mediated gene transfer of active transforming growth factor- β1 induces prolonged severe fibrosis in rat lung
    • Sime PJ, Xing Z, Graham FL, et al. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 1997; 100 (4): 768-76. (Pubitemid 27371693)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.4 , pp. 768-776
    • Sime, P.J.1    Xing, Z.2    Graham, F.L.3    Csaky, K.G.4    Gauldie, J.5
  • 136
    • 0032886794 scopus 로고    scopus 로고
    • Activation of rat alveolar macrophage-derived latent transforming growth factor β-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36
    • Yehualaeshet T, O'Connor R, Green-Johnson J, et al. Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36. Am J Pathol 1999; 155 (3): 841-51. (Pubitemid 29426830)
    • (1999) American Journal of Pathology , vol.155 , Issue.3 , pp. 841-851
    • Yehualaeshet, T.1    O'Connor, R.2    Green-Johnson, J.3    Mai, S.4    Silverstein, R.5    Murphy-Ullrich, J.E.6    Khalil, N.7
  • 138
    • 0026210618 scopus 로고
    • Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis
    • Khalil N, O'Connor RN, Unruh HW, et al. Increased production and immunohistochemical localization of transforming growth factor-beta in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 1991; 5 (2): 155-62.
    • (1991) Am J Respir Cell Mol Biol , vol.5 , Issue.2 , pp. 155-162
    • Khalil, N.1    O'Connor, R.N.2    Unruh, H.W.3
  • 139
    • 67749132419 scopus 로고    scopus 로고
    • TGF-beta and fibrosis in different organs: Molecular pathway imprints
    • Pohlers D, Brenmoehl J, Loffler I, et al. TGF-beta and fibrosis in different organs: molecular pathway imprints. Biochim Biophys Acta 2009; 1792 (8): 746-56.
    • (2009) Biochim Biophys Acta , vol.1792 , Issue.8 , pp. 746-756
    • Pohlers, D.1    Brenmoehl, J.2    Loffler, I.3
  • 140
  • 141
    • 55749109860 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1
    • Ahamed J, Burg N, Yoshinaga K, et al. In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1. Blood 2008; 112 (9): 3650-60.
    • (2008) Blood , vol.112 , Issue.9 , pp. 3650-3660
    • Ahamed, J.1    Burg, N.2    Yoshinaga, K.3
  • 142
    • 68949162163 scopus 로고    scopus 로고
    • In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1
    • Ahamed J, Janczak CA, Wittkowski KM, et al. In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. PLoS One 2009; 4 (8): e6608.
    • (2009) PLoS One , vol.4 , Issue.8
    • Ahamed, J.1    Janczak, C.A.2    Wittkowski, K.M.3
  • 143
    • 0030058699 scopus 로고    scopus 로고
    • Association of the small latent transforming growth factor-β with an eight cysteine repeat of its binding protein LTBP-1
    • Saharinen J, Taipale J, Keski-Oja J. Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1. EMBO J 1996; 15 (2): 245-53. (Pubitemid 26029204)
    • (1996) EMBO Journal , vol.15 , Issue.2 , pp. 245-253
    • Saharinen, J.1    Taipale, J.2    Keski-Oja, J.3
  • 144
    • 0035153291 scopus 로고    scopus 로고
    • Latent TGF-β binding protein LTBP-1 contains three potential extracellular matrix interacting domains
    • Unsold C, Hyytiainen M, Bruckner-Tuderman L, et al. Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains. J Cell Sci 2001; 114 (Pt 1): 187-97. (Pubitemid 32118068)
    • (2001) Journal of Cell Science , vol.114 , Issue.1 , pp. 187-197
    • Unsold, C.1    Hyytiainen, M.2    Bruckner-Tuderman, L.3    Keski-Oja, J.4
  • 146
    • 33745183811 scopus 로고    scopus 로고
    • Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury
    • Jenkins RG, Su X, Su G, et al. Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest 2006; 116 (6): 1606-14.
    • (2006) J Clin Invest , vol.116 , Issue.6 , pp. 1606-1614
    • Jenkins, R.G.1    Su, X.2    Su, G.3
  • 147
    • 27644538315 scopus 로고    scopus 로고
    • Integrin-mediated activation of latent transforming growth factor β
    • DOI 10.1007/s10555-005-5131-6
    • Sheppard D. Integrin-mediated activation of latent transforming growth factor beta. Cancer Metastasis Rev 2005; 24 (3): 395-402. (Pubitemid 41569979)
    • (2005) Cancer and Metastasis Reviews , vol.24 , Issue.3 , pp. 395-402
    • Sheppard, D.1
  • 148
    • 77954568888 scopus 로고    scopus 로고
    • Thy-1-integrin alpha v beta5 interactions inhibit lung fibroblast contractioninduced latent transforming growth factor-beta1 activation and myofibroblast differentiation
    • Zhou Y, Hagood JS, Lu B, et al. Thy-1-integrin alpha v beta5 interactions inhibit lung fibroblast contractioninduced latent transforming growth factor-beta1 activation and myofibroblast differentiation. J Biol Chem 2010; 285 (29): 22382-93.
    • (2010) J Biol Chem , vol.285 , Issue.29 , pp. 22382-93
    • Zhou, Y.1    Hagood, J.S.2    Lu, B.3
  • 149
    • 38949089708 scopus 로고    scopus 로고
    • Focal adhesion kinase: Targeting adhesion signaling pathways for therapeutic intervention
    • DOI 10.1158/1078-0432.CCR-07-2220
    • Parsons JT, Slack-Davis J, Tilghman R, et al. Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention. Clin Cancer Res 2008; 14 (3): 627-32. (Pubitemid 351231140)
    • (2008) Clinical Cancer Research , vol.14 , Issue.3 , pp. 627-632
    • Parsons, J.T.1    Slack-Davis, J.2    Tilghman, R.3    Roberts, W.G.4
  • 151
    • 55249089456 scopus 로고    scopus 로고
    • Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner
    • Ding Q, Gladson CL, Wu H, et al. Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner. J Biol Chem 2008; 283 (40): 26839-49.
    • (2008) J Biol Chem , vol.283 , Issue.40 , pp. 26839-49
    • Ding, Q.1    Gladson, C.L.2    Wu, H.3
  • 152
    • 77952763874 scopus 로고    scopus 로고
    • Downregulation of FAKrelated non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts
    • Cai GQ, Zheng A, Tang Q, et al. Downregulation of FAKrelated non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts. Exp Cell Res 2010; 316 (9): 1600-9.
    • (2010) Exp Cell Res , vol.316 , Issue.9 , pp. 1600-1609
    • Cai, G.Q.1    Zheng, A.2    Tang, Q.3
  • 153
    • 33847171545 scopus 로고    scopus 로고
    • Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts
    • DOI 10.1016/j.cellsig.2006.10.001, PII S0898656806002701
    • Horowitz JC, Rogers DS, Sharma V, et al. Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts. Cell Signal 2007; 19 (4): 761-71. (Pubitemid 46290691)
    • (2007) Cellular Signalling , vol.19 , Issue.4 , pp. 761-771
    • Horowitz, J.C.1    Rogers, D.S.2    Sharma, V.3    Vittal, R.4    White, E.S.5    Cui, Z.6    Thannickal, V.J.7
  • 154
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: The first ten years
    • DOI 10.1242/jcs.00373
    • Parsons JT. Focal adhesion kinase: the first ten years. J Cell Sci 2003; 116 (Pt 8): 1409-16. (Pubitemid 36527488)
    • (2003) Journal of Cell Science , vol.116 , Issue.8 , pp. 1409-1416
    • Parsons, J.T.1
  • 156
    • 58149234456 scopus 로고    scopus 로고
    • Protein kinase inhibitors in the treatment of pulmonary fibrosis
    • Garneau-Tsodikova S, Thannickal VJ. Protein kinase inhibitors in the treatment of pulmonary fibrosis. Curr Med Chem 2008; 15 (25): 2632-40.
    • (2008) Curr Med Chem , vol.15 , Issue.25 , pp. 2632-2640
    • Garneau-Tsodikova, S.1    Thannickal, V.J.2
  • 157
    • 0034747099 scopus 로고    scopus 로고
    • TGF-β1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion
    • Kutz SM, Hordines J, McKeown-Longo PJ, et al. TGFbeta1- induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion. J Cell Sci 2001; 114 (Pt 21): 3905-14. (Pubitemid 33094705)
    • (2001) Journal of Cell Science , vol.114 , Issue.21 , pp. 3905-3914
    • Kutz, S.M.1    Hordines, J.2    McKeown-Longo, P.J.3    Higgins, P.J.4
  • 158
    • 0034023127 scopus 로고    scopus 로고
    • Role of Ras and Mapks in TGFβ signaling
    • DOI 10.1016/S1359-6101(99)00026-X, PII S135961019900026X
    • Mulder KM. Role of Ras and Mapks in TGFbeta signaling. Cytokine Growth Factor Rev 2000; 11 (1-2): 23-35. (Pubitemid 30169723)
    • (2000) Cytokine and Growth Factor Reviews , vol.11 , Issue.1-2 , pp. 23-35
    • Mulder, K.M.1
  • 161
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • Lanford RE, Hildebrandt-Eriksen ES, Petri A, et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 2010; 327 (5962): 198-201.
    • (2010) Science , vol.327 , Issue.5962 , pp. 198-201
    • Lanford, R.E.1    Hildebrandt-Eriksen, E.S.2    Petri, A.3
  • 162
    • 78651247933 scopus 로고    scopus 로고
    • Micro- RNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha- PU.1 pathway
    • Ponomarev ED, Veremeyko T, Barteneva N, et al. Micro- RNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha- PU.1 pathway. Nat Med 2010; 17 (1): 64-70.
    • (2010) Nat Med , vol.17 , Issue.1 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3
  • 163
    • 68049083397 scopus 로고    scopus 로고
    • MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
    • Cheng Y, Liu X, Yang J, et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res 2009; 105 (2): 158-66.
    • (2009) Circ Res , vol.105 , Issue.2 , pp. 158-166
    • Cheng, Y.1    Liu, X.2    Yang, J.3
  • 166
    • 0033615977 scopus 로고    scopus 로고
    • Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo
    • Kawano Y, Fukata Y, Oshiro N, et al. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol 1999; 147 (5): 1023-38.
    • (1999) J Cell Biol , vol.147 , Issue.5 , pp. 1023-1038
    • Kawano, Y.1    Fukata, Y.2    Oshiro, N.3
  • 167
    • 31544433970 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effect of rho-kinase inhibitor in hypertensive glomerulosclerosis
    • DOI 10.1254/jphs.FMJ05003X5
    • Nishikimi T, Matsuoka H. Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of rho-kinase inhibitor in hypertensive glomerulosclerosis. J Pharmacol Sci 2006; 100 (1): 22-8. (Pubitemid 43161610)
    • (2006) Journal of Pharmacological Sciences , vol.100 , Issue.1 , pp. 22-28
    • Nishikimi, T.1    Matsuoka, H.2
  • 168
    • 34547666918 scopus 로고    scopus 로고
    • Rho kinase (ROCK) inhibitors
    • DOI 10.1097/FJC.0b013e318070d1bd, PII 0000534420070700000004
    • Liao JK, Seto M, Noma K. Rho kinase (ROCK) inhibitors. J Cardiovasc Pharmacol 2007; 50 (1): 17-24. (Pubitemid 47220442)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.1 , pp. 17-24
    • Liao, J.K.1    Seto, M.2    Noma, K.3
  • 169
    • 53849089211 scopus 로고    scopus 로고
    • Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
    • Oka M, Fagan KA, Jones PL, et al. Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension. Br J Pharmacol 2008; 155 (4): 444-54.
    • (2008) Br J Pharmacol , vol.155 , Issue.4 , pp. 444-454
    • Oka, M.1    Fagan, K.A.2    Jones, P.L.3
  • 170
    • 43049096072 scopus 로고    scopus 로고
    • Rho kinase inhibitors: A novel therapeutical intervention in asthma?
    • Schaafsma D, Gosens R, Zaagsma J, et al. Rho kinase inhibitors: a novel therapeutical intervention in asthma? Eur J Pharmacol 2008; 585 (2-3): 398-406.
    • (2008) Eur J Pharmacol , vol.585 , Issue.2-3 , pp. 398-406
    • Schaafsma, D.1    Gosens, R.2    Zaagsma, J.3
  • 172
    • 0034793893 scopus 로고    scopus 로고
    • Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells
    • DOI 10.1016/S0168-8278(01)00169-6, PII S0168827801001696
    • Murata T, Arii S, Nakamura T, et al. Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells. J Hepatol 2001; 35 (4): 474-81. (Pubitemid 32964446)
    • (2001) Journal of Hepatology , vol.35 , Issue.4 , pp. 474-481
    • Murata, T.1    Arii, S.2    Nakamura, T.3    Mori, A.4    Kaido, T.5    Furuyama, H.6    Furumoto, K.7    Nakao, T.8    Isobe, N.9    Imamura, M.10
  • 174
    • 55049134780 scopus 로고    scopus 로고
    • Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin
    • Boerma M, Fu Q, Wang J, et al. Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis 2008; 19 (7): 709-18.
    • (2008) Blood Coagul Fibrinolysis , vol.19 , Issue.7 , pp. 709-718
    • Boerma, M.1    Fu, Q.2    Wang, J.3
  • 176
    • 0037070964 scopus 로고    scopus 로고
    • 2-terminal peptide of α-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo
    • DOI 10.1083/jcb.200201049
    • Hinz B, Gabbiani G, Chaponnier C. The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol 2002; 157 (4): 657-63. (Pubitemid 34839793)
    • (2002) Journal of Cell Biology , vol.157 , Issue.4 , pp. 657-663
    • Hinz, B.1    Gabbiani, G.2    Chaponnier, C.3
  • 177
    • 0023263236 scopus 로고
    • Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis
    • Cantin AM, North SL, Fells GA, et al. Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J Clin Invest 1987; 79 (6): 1665-73. (Pubitemid 17117272)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.6 , pp. 1665-1673
    • Cantin, A.M.1    North, S.L.2    Fells, G.A.3
  • 178
    • 0024578662 scopus 로고
    • Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
    • Cantin AM, Hubbard RC, Crystal RG. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. AmRev Respir Dis 1989; 139 (2): 370-2. (Pubitemid 19057410)
    • (1989) American Review of Respiratory Disease , vol.139 , Issue.2 , pp. 370-372
    • Cantin, A.M.1    Hubbard, R.C.2    Crystal, R.G.3
  • 180
    • 69949114515 scopus 로고    scopus 로고
    • NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
    • Hecker L, Vittal R, Jones T, et al. NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med 2009; 15 (9): 1077-81.
    • (2009) Nat Med , vol.15 , Issue.9 , pp. 1077-1081
    • Hecker, L.1    Vittal, R.2    Jones, T.3
  • 181
    • 77953054445 scopus 로고    scopus 로고
    • The case for personalized medicine
    • Abrahams E, Silver M. The case for personalized medicine. J Diabetes Sci Technol 2009; 3 (4): 680-4.
    • (2009) J Diabetes Sci Technol , vol.3 , Issue.4 , pp. 680-684
    • Abrahams, E.1    Silver, M.2
  • 182
    • 67349165410 scopus 로고    scopus 로고
    • MICA polymorphisms and decreased expression of the MICAreceptorNKG2Dcontribute to idiopathic pulmonary fibrosis susceptibility
    • Aquino-Galvez A, Perez-Rodriguez M, Camarena A, et al. MICA polymorphisms and decreased expression of the MICAreceptorNKG2Dcontribute to idiopathic pulmonary fibrosis susceptibility. Hum Genet 2009; 125 (5-6): 639-48.
    • (2009) Hum Genet , vol.125 , Issue.5-6 , pp. 639-648
    • Aquino-Galvez, A.1    Perez-Rodriguez, M.2    Camarena, A.3
  • 183
    • 57049139310 scopus 로고    scopus 로고
    • MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis
    • Checa M, Ruiz V, Montano M, et al. MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis. Hum Genet 2008; 124 (5): 465-72.
    • (2008) Hum Genet , vol.124 , Issue.5 , pp. 465-472
    • Checa, M.1    Ruiz, V.2    Montano, M.3
  • 184
    • 43249084804 scopus 로고    scopus 로고
    • MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis
    • Rosas IO, Richards TJ, Konishi K, et al. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med 2008; 5 (4): e93.
    • (2008) PLoS Med , vol.5 , Issue.4
    • Rosas, I.O.1    Richards, T.J.2    Konishi, K.3
  • 185
    • 38049079133 scopus 로고    scopus 로고
    • Serumlevels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis
    • Daniil ZD, Papageorgiou E,KoutsokeraA, et al. Serumlevels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis. PulmPharmacol Ther 2008; 21 (1): 26-31.
    • (2008) PulmPharmacol Ther , vol.21 , Issue.1 , pp. 26-31
    • Daniil, Z.D.1    Papageorgiou, E.2    Koutsokera, A.3
  • 186
    • 63849228099 scopus 로고    scopus 로고
    • Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis
    • Kinder BW, Brown KK, McCormack FX, et al. Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis. Chest 2009; 135 (6): 1557-63.
    • (2009) Chest , vol.135 , Issue.6 , pp. 1557-1563
    • Kinder, B.W.1    Brown, K.K.2    McCormack, F.X.3
  • 187
    • 65249160219 scopus 로고    scopus 로고
    • Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis
    • Prasse A, Probst C, Bargagli E, et al. Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2009; 179 (8): 717-23.
    • (2009) Am J Respir Crit Care Med , vol.179 , Issue.8 , pp. 717-723
    • Prasse, A.1    Probst, C.2    Bargagli, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.