Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition

Critical Care Medicine

Volumn 40, Issue 2, 2012, Pages 510-517

  Cabrera Benítez, Nuria E ^a,b,c   Parotto, Matteo ^a,d,e,f   Post, Martin ^a,d,e,f   Han, Bing ^a,d,e   Spieth, Peter M ^a,d,e   Cheng, Wei Erh ^a,d,e   Valladares, Francisco ^b,g   Villar, Jesús ^a,b,c   Liu, Mingayo ^d   Sato, Masaaki ^d   Zhang, Haibo ^a,d,e,h   Slutsky, Arthur S ^a,e,i  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f HOSPITAL FOR SICK CHILDREN   (Canada)

^g UNIVERSIDAD DE LA LAGUNA   (Spain)

^h GUANGZHOU MEDICAL UNIVERSITY   (China)

ⁱ KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

acute lung injury; extracellular matrix; ventilatorinduced lung injury

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; CYTOKERATIN 8; HYDROCHLORIC ACID; HYDROXYPROLINE; SURFACTANT PROTEIN B; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VIMENTIN;

ACID ASPIRATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG MECHANICS; MALE; MECHANICAL STRESS; MOUSE; NONHUMAN; PATHOGENESIS; PEAK INSPIRATORY FLOW; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT DURATION;

ANIMALS; BIOPSY, NEEDLE; BLOTTING, WESTERN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EPITHELIAL-MESENCHYMAL TRANSITION; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; POSITIVE-PRESSURE RESPIRATION; PULMONARY FIBROSIS; RANDOM ALLOCATION; REFERENCE VALUES; RESPIRATORY MECHANICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STRESS, MECHANICAL; VENTILATOR-INDUCED LUNG INJURY;

EID: 84856133737     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31822f09d7     Document Type: Article

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