The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action

Pharmacological Reviews

Volumn 65, Issue 2, 2013, Pages 545-577

  Khan, Shahriar M ^a   Sleno, Rory ^a   Gora, Sarah ^a   Zylbergold, Peter ^a   Laverdure, Jean Philippe ^b   Labbé, Jean Claude ^b,c   Miller, Gregory J ^a,d   Hébert, Terence E ^a  

^a MCGILL UNIVERSITY   (Canada)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d CATHOLIC UNIVERSITY OF AMERICA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOLAMINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; MITOGEN ACTIVATED PROTEIN KINASE; MORPHINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; ADENYLATE CYCLASE; CATION CHANNEL; DOPAMINE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT 1; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT 2; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT 3; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT 4; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT 5; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT 1; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT 2; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT 3; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT 7; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; ISOENZYME; KIR3 CHANNEL; PHOSDUCIN LIKE PROTEIN 1; POTASSIUM CHANNEL; PROTEIN; RGS PROTEIN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT CALCIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CAENORHABDITIS ELEGANS; CELL ORGANELLE; DICTYOSTELIUM; DROSOPHILA MELANOGASTER; DRUG MECHANISM; ENDOPLASMIC RETICULUM; FEMALE FERTILITY; FISH; GENE MUTATION; GENE STRUCTURE; HUMAN; NEUROSPORA CRASSA; NONHUMAN; PHYLOGENY; PLANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; BIODIVERSITY; CELL DIVISION; CYTOSKELETON; DRUG TARGETING; ENDOSOME; ENZYME SPECIFICITY; EUKARYOTE; GENE INACTIVATION; GENE SILENCING; GENE TARGETING; GENETIC POLYMORPHISM; GOLGI COMPLEX; INVERTEBRATE; MITOCHONDRION; MOLECULAR PHYLOGENY; PHENOTYPE; PROTEIN ASSEMBLY; PROTEIN SUBUNIT;

ANIMALS; BINDING SITES; DRUG DISCOVERY; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; MODELS, MOLECULAR; ORGANELLES; PHYLOGENY; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; SPECIES SPECIFICITY;

EID: 84873912942     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.111.005603     Document Type: Article

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