G-protein β3-subunit 825T allele is associated with enhanced human atrial inward rectifier potassium currents

Circulation

Volumn 102, Issue 6, 2000, Pages 692-697

  Dobrev, D ^a   Wettwer, E ^a   Himmel, H M ^a   Kortner, A ^a   Kuhlisch, E ^a   Schuler S ^a   Siffert, W ^b   Ravens, U ^a,c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c Institut für Pharmakologie und Toxikologie   (Germany)

Author keywords

Adenosine; Carbachol; Genes; Ions; Myocytes

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT;

ADULT; AGED; ALLELE; ARTICLE; BETA CHAIN; CORONARY ARTERY BYPASS SURGERY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HEART ATRIUM; HEART MUSCLE POTENTIAL; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POTASSIUM CURRENT; PRIORITY JOURNAL;

EID: 0034622577     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.102.6.692     Document Type: Article

References (22)

1. Role of sodium-hydrogen exchange in the proliferation of immortalized lymphoblasts from patients with essential hypertension and normotensive subjects
2. Sodium-proton exchange and primary hypertension
3. 3 subunit variant with hypertension
4. 3 subunit gene and lower renin and elevated diastolic blood pressure levels
5. 3 subunit gene variant and blood pressure variation in Canadian Oji-Cree
6. 3 subunit (GNB3) variant in causation of essential hypertension
7. + channel, I(K,ACh)
8. G protein regulation of potassium ion channels
9. The expanding spectrum of G protein diseases
10. Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle
11. Recommendations regarding quantification in M-mode echocardiographic measurements
12. Differences between outward currents of human atrial and subepicardial ventricular myocytes
13. JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements
14. Fundamentals of genetic epidemiology
15. Genetic variability of G protein reactivity as a risk factor for coronary artery disease and myocardial infarction
16. 3 subunit gene and myocardial infarction
17. Ionic mechanisms of electrical remodeling in human atrial fibrillation
18. + current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation
19. + channel response to acetylcholine and to G protein-mediated activation in atrial myocytes isolated from failing human hearts
20. G-protein diseases furnish a model for the turn-on switch
21. Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins
22. Functional characterisation of a novel splice variant of the human G protein subunit Gβ3