-
1
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
Zon LI, Peterson RT. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov. 2005;4:35-44.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
-
2
-
-
33749208496
-
Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant
-
Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast. 2000;17:294-301.
-
(2000)
Yeast
, vol.17
, pp. 294-301
-
-
Nasevicius, A.1
Larson, J.2
Ekker, S.C.3
-
4
-
-
0037143447
-
Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis
-
Habeck H, Odenthal J, Walderich B, Maischein H, Schulte-Merker S, Tubingen 2000 Screen Consortium. Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol. 2002;12:1405-1412.
-
(2002)
Curr Biol
, vol.12
, pp. 1405-1412
-
-
Habeck, H.1
Odenthal, J.2
Walderich, B.3
Maischein, H.4
Schulte-Merker, S.5
-
5
-
-
0038624399
-
Phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development
-
Lawson ND, Mugford JW, Diamond BA, Weinstein BM. Phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev. 2003;17:1346-1351.
-
(2003)
Genes Dev
, vol.17
, pp. 1346-1351
-
-
Lawson, N.D.1
Mugford, J.W.2
Diamond, B.A.3
Weinstein, B.M.4
-
6
-
-
0042510315
-
bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish
-
Leung T, Bischof J, Soll I, et al. bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish. Development. 2003;130:3639-3649.
-
(2003)
Development
, vol.130
, pp. 3639-3649
-
-
Leung, T.1
Bischof, J.2
Soll, I.3
-
7
-
-
0037044854
-
Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS)
-
Tanimoto T, Jin ZG, Berk BC. Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). J Biol Chem. 2002;277:42997-43001.
-
(2002)
J Biol Chem
, vol.277
, pp. 42997-43001
-
-
Tanimoto, T.1
Jin, Z.G.2
Berk, B.C.3
-
8
-
-
0037738524
-
Transactivation of KDR/Flk-1 by the B2 receptor induces tube formation in human coronary endothelial cells
-
Miura S, Matsuo Y, Saku K. Transactivation of KDR/Flk-1 by the B2 receptor induces tube formation in human coronary endothelial cells. Hypertension. 2003;41:1118-1123.
-
(2003)
Hypertension
, vol.41
, pp. 1118-1123
-
-
Miura, S.1
Matsuo, Y.2
Saku, K.3
-
10
-
-
1542411718
-
Angiotensin II potentiates vascular endothelial growth factor-induced proliferation and network formation of endothelial progenitor cells
-
Imanishi T, Hano T, Nishio I. Angiotensin II potentiates vascular endothelial growth factor-induced proliferation and network formation of endothelial progenitor cells. Hypertens Res. 2004;27:101-108.
-
(2004)
Hypertens Res
, vol.27
, pp. 101-108
-
-
Imanishi, T.1
Hano, T.2
Nishio, I.3
-
11
-
-
0038407691
-
Emerging role of endothelin-1 in tumor angiogenesis
-
Bagnato A, Spinella F. Emerging role of endothelin-1 in tumor angiogenesis. Trends Endocrinol Metab. 2003;14:44-50.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 44-50
-
-
Bagnato, A.1
Spinella, F.2
-
12
-
-
0031015426
-
Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency
-
Offermanns S, Mancino V, Revel JP, Simon MI. Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency. Science. 1997;275:533-536.
-
(1997)
Science
, vol.275
, pp. 533-536
-
-
Offermanns, S.1
Mancino, V.2
Revel, J.P.3
Simon, M.I.4
-
13
-
-
20444423842
-
Essential role for G13 in endothelial cells during embryonic development
-
U S A
-
Ruppel KM, Willison D, Kataoka H, et al. Essential role for G13 in endothelial cells during embryonic development. Proc Natl Acad Sci U S A. 2005;102:8281-8286.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 8281-8286
-
-
Ruppel, K.M.1
Willison, D.2
Kataoka, H.3
-
14
-
-
0035979691
-
A role for thrombin receptor signaling in endothelial cells during embryonic development
-
Griffin CT, Srinivasan Y, Zheng YW, Huang W, Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science. 2001;293:1666-1670.
-
(2001)
Science
, vol.293
, pp. 1666-1670
-
-
Griffin, C.T.1
Srinivasan, Y.2
Zheng, Y.W.3
Huang, W.4
Coughlin, S.R.5
-
15
-
-
0242474429
-
Functional genomic dissection of multimeric protein families in zebrafish
-
Cheng KC, Levenson R, Robishaw JD. Functional genomic dissection of multimeric protein families in zebrafish. Dev Dyn. 2003;228:555-567.
-
(2003)
Dev Dyn
, vol.228
, pp. 555-567
-
-
Cheng, K.C.1
Levenson, R.2
Robishaw, J.D.3
-
16
-
-
0032480009
-
Embryonic cardiomyocyte hypoplasia and craniofacial defects in Gαq/11 mutant mice
-
Offermanns S, Zhao LP, Gohla A, Sarosi I, Simon MI, Wilkie TM. Embryonic cardiomyocyte hypoplasia and craniofacial defects in Gαq/11 mutant mice. EMBO J. 1998;17:4304-4312.
-
(1998)
EMBO J
, vol.17
, pp. 4304-4312
-
-
Offermanns, S.1
Zhao, L.P.2
Gohla, A.3
Sarosi, I.4
Simon, M.I.5
Wilkie, T.M.6
-
17
-
-
0038757626
-
Heterotrimeric Gαq/11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling
-
Zeng H, Zhao D, Yang S, Datta K, Mukhopadhyay D. Heterotrimeric Gα-q/11 proteins function upstream of vascular endothelial growth factor (VEGF) receptor-2 (KDR) phosphorylation in vascular permeability factor/VEGF signaling. J Biol Chem. 2003;278:20738-20745.
-
(2003)
J Biol Chem
, vol.278
, pp. 20738-20745
-
-
Zeng, H.1
Zhao, D.2
Yang, S.3
Datta, K.4
Mukhopadhyay, D.5
-
18
-
-
0037458639
-
Loss of G protein γ7 alters behavior and reduces striatal Gαo level and cAMP production
-
Schwindinger WF, Betz KS, Giger KE, Sabol A, Bronson SK, Robishaw JD. Loss of G protein γ7 alters behavior and reduces striatal Gαo level and cAMP production. J Biol Chem. 2003;278:6575-6579.
-
(2003)
J Biol Chem
, vol.278
, pp. 6575-6579
-
-
Schwindinger, W.F.1
Betz, K.S.2
Giger, K.E.3
Sabol, A.4
Bronson, S.K.5
Robishaw, J.D.6
-
19
-
-
4344684893
-
Mice with deficiency of G protein γ3 are lean and have seizures
-
Schwindinger WF, Giger KE, Betz KS, et al. Mice with deficiency of G protein γ3 are lean and have seizures. Mol Cell Biol. 2004;24:7758-7768.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7758-7768
-
-
Schwindinger, W.F.1
Giger, K.E.2
Betz, K.S.3
-
20
-
-
0035952766
-
Heterotrimeric G-protein betagamma-dimers in growth and differentiation
-
Schwindinger WF, Robishaw JD. Heterotrimeric G-protein betagamma-dimers in growth and differentiation. Oncogene. 2001;20:1653-1660.
-
(2001)
Oncogene
, vol.20
, pp. 1653-1660
-
-
Schwindinger, W.F.1
Robishaw, J.D.2
-
21
-
-
2942623922
-
Translating G protein subunit diversity into functional specificity
-
Robishaw JD, Berlot CH. Translating G protein subunit diversity into functional specificity. Curr Opin Cell Biol. 2004;6:206-209.
-
(2004)
Curr Opin Cell Biol
, vol.6
, pp. 206-209
-
-
Robishaw, J.D.1
Berlot, C.H.2
-
22
-
-
0033780376
-
Effective targeted gene "knockdown" in zebrafish
-
Nasevicius A, Ekker SC. Effective targeted gene "knockdown" in zebrafish. Nat Genet. 2000;26:216-220.
-
(2000)
Nat Genet
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
23
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer. 2003;3:401-410.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
24
-
-
0031040497
-
The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation
-
Liao W, Bisgrove BW, Sawyer H, et al. The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiation. Development. 1997;124:381-389.
-
(1997)
Development
, vol.124
, pp. 381-389
-
-
Liao, W.1
Bisgrove, B.W.2
Sawyer, H.3
-
25
-
-
0034604096
-
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
-
Heisenberg CP, Tada M, Rauch GJ, et al. Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature. 2000;405:76-81.
-
(2000)
Nature
, vol.405
, pp. 76-81
-
-
Heisenberg, C.P.1
Tada, M.2
Rauch, G.J.3
-
26
-
-
0037672533
-
The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry
-
Long S, Ahmad N, Rebagliati M. The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry. Development. 2003;130:2303-2316.
-
(2003)
Development
, vol.130
, pp. 2303-2316
-
-
Long, S.1
Ahmad, N.2
Rebagliati, M.3
-
27
-
-
4644288188
-
+-ATPase in maintaining ventricular cardiomyocyte morphology and viability in zebrafish
-
+-ATPase in maintaining ventricular cardiomyocyte morphology and viability in zebrafish. Circ Res. 2004;95:595-603.
-
(2004)
Circ Res
, vol.95
, pp. 595-603
-
-
Yuan, S.1
Joseph, E.M.2
-
29
-
-
0035170549
-
Fgf signaling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos
-
Shinya M, Koshida S, Sawada A, Kuroiwa A, Takeda H. Fgf signaling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos. Development. 2001;128:4153-4164.
-
(2001)
Development
, vol.128
, pp. 4153-4164
-
-
Shinya, M.1
Koshida, S.2
Sawada, A.3
Kuroiwa, A.4
Takeda, H.5
-
30
-
-
0037326702
-
Signal transduction by vascular endothelial growth factor receptors
-
Claesson-Welsh L. Signal transduction by vascular endothelial growth factor receptors. Biochem Soc Trans. 2003;31:20-24.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 20-24
-
-
Claesson-Welsh, L.1
-
31
-
-
0035355472
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLCγ and DNA synthesis in vascular endothelial cells
-
Takahashi T, Yamaguchi S, Chida K, Shibuya M. A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLCγ and DNA synthesis in vascular endothelial cells. EMBO J. 2001;20:2768-2778.
-
(2001)
EMBO J
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
32
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells
-
Richard DE, Berra E, Pouyssegur J. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1α in vascular smooth muscle cells. J Biol Chem. 2000;275:26765-26771.
-
(2000)
J Biol Chem
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
33
-
-
0029061789
-
Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells
-
Williams B, Baker AQ, Gallacher B, Lodwick D. Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells. Hypertension. 1995;25:913-917.
-
(1995)
Hypertension
, vol.25
, pp. 913-917
-
-
Williams, B.1
Baker, A.Q.2
Gallacher, B.3
Lodwick, D.4
-
34
-
-
12844274258
-
Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signaling
-
Albig AR, Schiemann WP. Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signaling. Mol Biol Cell. 2005;16:609-625.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 609-625
-
-
Albig, A.R.1
Schiemann, W.P.2
-
35
-
-
0035958899
-
Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors: A novel platform for integrative signaling by these receptor classes in mammalian cells
-
Alderton F, Rakhit S, Kong KC, et al. Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors: a novel platform for integrative signaling by these receptor classes in mammalian cells. J Biol Chem. 2001;276:28578-28585.
-
(2001)
J Biol Chem
, vol.276
, pp. 28578-28585
-
-
Alderton, F.1
Rakhit, S.2
Kong, K.C.3
-
36
-
-
0032875363
-
Gαq/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes
-
Imamura T, Vollenweider P, Egawa K, et al. Gαq/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes. Mol Cell Biol. 1999;19:6765-6774.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6765-6774
-
-
Imamura, T.1
Vollenweider, P.2
Egawa, K.3
-
37
-
-
0035831492
-
Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gαi2 in human intestinal smooth muscle: Gβγ-dependent mitogen-activated protein kinase activation and growth
-
Kuemmerle JF, Murthy KS. Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gαi2 in human intestinal smooth muscle: Gβγ-dependent mitogen-activated protein kinase activation and growth. J Biol Chem. 2001;276:7187-7194.
-
(2001)
J Biol Chem
, vol.276
, pp. 7187-7194
-
-
Kuemmerle, J.F.1
Murthy, K.S.2
-
38
-
-
3142766112
-
Visualization of G protein βγ dimers using bimolecular fluorescence complementation demonstrates roles for both Gβ and Gγ in subcellular targeting
-
Hynes TR, Tang L, Mervine SM, et al. Visualization of G protein βγ dimers using bimolecular fluorescence complementation demonstrates roles for both Gβ and Gγ in subcellular targeting. J Biol Chem. 2004;279:30279-30286.
-
(2004)
J Biol Chem
, vol.279
, pp. 30279-30286
-
-
Hynes, T.R.1
Tang, L.2
Mervine, S.M.3
-
39
-
-
0034737450
-
Leukotriene D4 triggers an association between Gβγ subunits and phospholipase C-gamma1 in intestinal epithelial cells
-
Thodeti CK, Adolfsson J, Juhas M, Sjolander A. Leukotriene D4 triggers an association between Gβγ subunits and phospholipase C-gamma1 in intestinal epithelial cells. J Biol Chem. 2000;275:9849-9853.
-
(2000)
J Biol Chem
, vol.275
, pp. 9849-9853
-
-
Thodeti, C.K.1
Adolfsson, J.2
Juhas, M.3
Sjolander, A.4
-
40
-
-
15744363780
-
p84, a new Gβγ-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110γ
-
Suire S, Coadwell J, Ferguson GJ, Davidson K, Hawkins P, Stephens L. p84, a new Gβγ-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110γ. Curr Biol. 2005;15:566-570.
-
(2005)
Curr Biol
, vol.15
, pp. 566-570
-
-
Suire, S.1
Coadwell, J.2
Ferguson, G.J.3
Davidson, K.4
Hawkins, P.5
Stephens, L.6
-
41
-
-
29644446699
-
Specific role of p85/p110β in GTP-binding protein-mediated activation of Akt
-
Kubo H, Hazeki K, Takasuga S, Hazeki O. Specific role of p85/p110β in GTP-binding protein-mediated activation of Akt. Biochem J. 2005;392:607-614.
-
(2005)
Biochem J
, vol.392
, pp. 607-614
-
-
Kubo, H.1
Hazeki, K.2
Takasuga, S.3
Hazeki, O.4
-
42
-
-
0035952766
-
Heterotrimeric G protein βγ-dimers in growth and differentiation
-
Schwindinger WF, Robishaw JD. Heterotrimeric G protein βγ-dimers in growth and differentiation. Oncogene. 2001;20:1653-1660.
-
(2001)
Oncogene
, vol.20
, pp. 1653-1660
-
-
Schwindinger, W.F.1
Robishaw, J.D.2
-
43
-
-
0033546420
-
Ribozyme approach identifies a functional association between the G protein β1γ7 subunits in the beta-adrenergic receptor signaling pathway
-
Wang Q, Mullah BK, Robishaw JD. Ribozyme approach identifies a functional association between the G protein β1γ7 subunits in the beta-adrenergic receptor signaling pathway. J Biol Chem. 1999;274:17365-17371.
-
(1999)
J Biol Chem
, vol.274
, pp. 17365-17371
-
-
Wang, Q.1
Mullah, B.K.2
Robishaw, J.D.3
-
44
-
-
0033626331
-
Gβγ subunit combinations differentially modulate receptor and effector coupling in vivo
-
Robillard L, Ethier N, Lachance M, Hebert TE. Gβγ subunit combinations differentially modulate receptor and effector coupling in vivo. Cell Signal. 2000;12:673-682.
-
(2000)
Cell Signal
, vol.12
, pp. 673-682
-
-
Robillard, L.1
Ethier, N.2
Lachance, M.3
Hebert, T.E.4
-
45
-
-
0035807026
-
Receptor-G protein γ specificity: Gγ11 shows unique potency for A1 adenosine and 5-HT 1A receptors
-
Lim WK, Myung CS, Garrison JC, Neubig RR. Receptor-G protein γ specificity: Gγ11 shows unique potency for A1 adenosine and 5-HT 1A receptors. Biochemistry. 2001;40:10532-10541.
-
(2001)
Biochemistry
, vol.40
, pp. 10532-10541
-
-
Lim, W.K.1
Myung, C.S.2
Garrison, J.C.3
Neubig, R.R.4
|