Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

Cell

Volumn 107, Issue 2, 2001, Pages 183-194

  Schaefer, Matthias ^a   Petronczki, Mark ^a   Dorner, Daniela ^a   Forte, Michael ^b   Knoblich, Juergen A ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PARTNER OF INSCUTEABLE PROTEIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTERIOR POSTERIOR AXIS; ARTICLE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; MITOSIS; NERVOUS SYSTEM; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SENSE ORGAN; STEM CELL;

ANIMALIA; HEXAPODA; INSECTA;

EID: 0035913905     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00521-9     Document Type: Article

References (50)

1. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
2. Asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation
3. Extrinsic cues, intrinsic cues and microfilaments regulate asymmetric protein localization in Drosophila neuroblasts
4. Cell polarity in yeast
5. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila
6. Asymmetric cell division: Fly neuroblast meets worm zygote
7. An eye-specific Gβ subunit essential for termination of the phototransduction cascade
8. Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila
9. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
10. Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
11. Asymmetric segregation of the homeodomain protein Prospero during Drosophila development
12. Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
13. Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions
14. Molecular analysis of EMS-induced frizzled mutations in Drosophila melanogaster
15. Heritable gene silencing in Drosophila using double-stranded RNA
16. Asymmetric cell division during animal development
17. Asymmetric segregation of Numb and Prospero during cell division
18. Deletion analysis of the Drosophila inscuteable protein reveals domains for cortical localization and asymmetric localization
19. Inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskeleton adaptor protein
20. Role of inscuteable in orienting asymmetric cell divisions in Drosophila
21. Control of spindle orientation in Drosophila by the Par-3-related PDZ- domain protein Bazooka
22. G Protein signaling from activated rat frizzled-1 to the beta-catenin- Lef-Tcf pathway
23. Mutations in the GTP-binding site of GSα alter stimulation of adenylyl cyclase
24. Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with Gαi2
25. AGS3 inhibits GDP dissociation from gα subunits of the Gi family and rhodopsin-dependent activation of transducin
26. Nucleocytoplasmic shuttling of the Cdc42p exchange factor Cdc24p
27. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
28. In vivo functions of heterotrimeric G proteins: Studies in Gα-deficient mice
29. A cell's sense of direction
30. The Drosophila gastrulation gene concertina encodes a G alpha-like protein
31. Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila
32. DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila
33. A Drosophila melanogaster G protein alpha subunit gene is expressed primarily in embryos and pupae
34. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
35. Ulcerative colitis and adenocarcinoma of the colon in G alpha i2- deficient mice
36. A protein complex containing inscuteable and the gα-binding protein pins orients asymmetric cell divisions in Drosophila
37. Bazooka recruits inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts
38. Miranda mediates asymmetric protein and RNA localization in the developing nervous system
39. Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations
40. Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila
41. The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila
42. Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos
43. Receptor-independent activators of heterotrimeric G protein signaling pathways
44. Immunological and molecular characterization of Gα-like proteins in the Drosophila central nervous system
45. Bazooka provides an apical cue for inscuteable localization in Drosophila neuroblasts
46. Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts
47. A Gβ protein in the Drosophila compound eye is different from that in the brain
48. Cloning of a Drosophila melanogaster guanine nucleotide regulatory protein beta-subunit gene and characterization of its expression during development
49. Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization
50. G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos